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A Markedly Improved Synthetic Approach for the Preparation of Multifunctional Au-DNA Nanoparticle Conjugates Modified with Optical and MR Imaging Probes.

Rotz MW, Holbrook RJ, MacRenaris KW, Meade TJ.

Bioconjug Chem. 2018 Nov 21;29(11):3544-3549. doi: 10.1021/acs.bioconjchem.8b00504. Epub 2018 Oct 10.


Effect of Magnetic Coupling on Water Proton Relaxivity in a Series of Transition Metal GdIII Complexes.

Lilley LM, Du K, Krzyaniak MD, Parigi G, Luchinat C, Harris TD, Meade TJ.

Inorg Chem. 2018 May 21;57(10):5810-5819. doi: 10.1021/acs.inorgchem.8b00120. Epub 2018 May 1.


Synthesis and evaluation of MR probes for targeted-reporter imaging.

Verma KD, Massing JO, Kamper SG, Carney CE, MacRenaris KW, Basilion JP, Meade TJ.

Chem Sci. 2017 Aug 1;8(8):5764-5768. doi: 10.1039/c7sc02217d. Epub 2017 Jun 13.


Calcium-Induced Morphological Transitions in Peptide Amphiphiles Detected by 19F-Magnetic Resonance Imaging.

Preslar AT, Lilley LM, Sato K, Zhang S, Chia ZK, Stupp SI, Meade TJ.

ACS Appl Mater Interfaces. 2017 Nov 22;9(46):39890-39894. doi: 10.1021/acsami.7b07828. Epub 2017 Nov 10.


Injectable biomimetic liquid crystalline scaffolds enhance muscle stem cell transplantation.

Sleep E, Cosgrove BD, McClendon MT, Preslar AT, Chen CH, Sangji MH, Pérez CMR, Haynes RD, Meade TJ, Blau HM, Stupp SI.

Proc Natl Acad Sci U S A. 2017 Sep 19;114(38):E7919-E7928. doi: 10.1073/pnas.1708142114. Epub 2017 Sep 5.


Shape-Dependent Relaxivity of Nanoparticle-Based T1 Magnetic Resonance Imaging Contrast Agents.

Culver KS, Shin YJ, Rotz MW, Meade TJ, Hersam MC, Odom TW.

J Phys Chem C Nanomater Interfaces. 2016 Sep 29;120(38):22103-22109. doi: 10.1021/acs.jpcc.6b08362. Epub 2016 Sep 13.


Nanodiamond-Gadolinium(III) Aggregates for Tracking Cancer Growth In Vivo at High Field.

Rammohan N, MacRenaris KW, Moore LK, Parigi G, Mastarone DJ, Manus LM, Lilley LM, Preslar AT, Waters EA, Filicko A, Luchinat C, Ho D, Meade TJ.

Nano Lett. 2016 Dec 14;16(12):7551-7564. Epub 2016 Nov 15.


Gd(III)-Gold Nanoconjugates Provide Remarkable Cell Labeling for High Field Magnetic Resonance Imaging.

Rammohan N, Holbrook RJ, Rotz MW, MacRenaris KW, Preslar AT, Carney CE, Reichova V, Meade TJ.

Bioconjug Chem. 2017 Jan 18;28(1):153-160. doi: 10.1021/acs.bioconjchem.6b00389. Epub 2016 Sep 1.


(19)F Magnetic Resonance Imaging Signals from Peptide Amphiphile Nanostructures Are Strongly Affected by Their Shape.

Preslar AT, Tantakitti F, Park K, Zhang S, Stupp SI, Meade TJ.

ACS Nano. 2016 Aug 23;10(8):7376-84. doi: 10.1021/acsnano.6b00267. Epub 2016 Jul 26.


Magnetic barcode imaging for contrast agents.

Hung AH, Lilley LM, Hu F, Harrison VS, Meade TJ.

Magn Reson Med. 2017 Mar;77(3):970-978. doi: 10.1002/mrm.26175. Epub 2016 Apr 8.


Gd(III)-Dithiolane Gold Nanoparticles for T1-Weighted Magnetic Resonance Imaging of the Pancreas.

Holbrook RJ, Rammohan N, Rotz MW, MacRenaris KW, Preslar AT, Meade TJ.

Nano Lett. 2016 May 11;16(5):3202-9. doi: 10.1021/acs.nanolett.6b00599. Epub 2016 Apr 20.


Cell-Permeable Esterase-Activated Ca(II)-Sensitive MRI Contrast Agent.

MacRenaris KW, Ma Z, Krueger RL, Carney CE, Meade TJ.

Bioconjug Chem. 2016 Feb 17;27(2):465-73. doi: 10.1021/acs.bioconjchem.5b00561. Epub 2016 Jan 6.


DNA-gadolinium-gold nanoparticles for in vivo T1 MR imaging of transplanted human neural stem cells.

Nicholls FJ, Rotz MW, Ghuman H, MacRenaris KW, Meade TJ, Modo M.

Biomaterials. 2016 Jan;77:291-306. doi: 10.1016/j.biomaterials.2015.11.021. Epub 2015 Nov 14.


Correction to Gd(III)-Labeled Peptide Nanofibers for Reporting on Biomaterial Localization in Vivo.

Preslar AT, Parigi G, McClendon MT, Sefick SS, Moyer TJ, Haney CR, Waters EA, MacRenaris KW, Luchinat C, Stupp SI, Meade TJ.

ACS Nano. 2015 Nov 24;9(11):11502. doi: 10.1021/acsnano.5b06496. Epub 2015 Oct 30. No abstract available.


Targeted delivery of gold nanoparticle contrast agents for reporting gene detection by magnetic resonance imaging.

Vistain LF, Rotz MW, Rathore R, Preslar AT, Meade TJ.

Chem Commun (Camb). 2016 Jan 4;52(1):160-3. doi: 10.1039/c5cc06565h.


Tuning cobalt(III) Schiff base complexes as activated protein inhibitors.

Heffern MC, Reichova V, Coomes JL, Harney AS, Bajema EA, Meade TJ.

Inorg Chem. 2015 Sep 21;54(18):9066-74. doi: 10.1021/acs.inorgchem.5b01415. Epub 2015 Sep 2.


Targeted Inhibition of Snail Activity in Breast Cancer Cells by Using a Co(III) -Ebox Conjugate.

Vistain LF, Yamamoto N, Rathore R, Cha P, Meade TJ.

Chembiochem. 2015 Sep 21;16(14):2065-72. doi: 10.1002/cbic.201500289. Epub 2015 Aug 25.


Water-soluble lipophilic MR contrast agents for cell membrane labeling.

Carney CE, MacRenaris KW, Meade TJ.

J Biol Inorg Chem. 2015 Sep;20(6):971-7. doi: 10.1007/s00775-015-1280-4. Epub 2015 Jul 28.


Synthesis and Evaluation of Gd(III) -Based Magnetic Resonance Contrast Agents for Molecular Imaging of Prostate-Specific Membrane Antigen.

Banerjee SR, Ngen EJ, Rotz MW, Kakkad S, Lisok A, Pracitto R, Pullambhatla M, Chen Z, Shah T, Artemov D, Meade TJ, Bhujwalla ZM, Pomper MG.

Angew Chem Int Ed Engl. 2015 Sep 7;54(37):10778-82. doi: 10.1002/anie.201503417. Epub 2015 Jul 23.


Multimeric Near IR-MR Contrast Agent for Multimodal In Vivo Imaging.

Harrison VS, Carney CE, MacRenaris KW, Waters EA, Meade TJ.

J Am Chem Soc. 2015 Jul 22;137(28):9108-16. doi: 10.1021/jacs.5b04509. Epub 2015 Jul 14.


Theranostic Magnetic Nanostructures (MNS) for Cancer.

Nandwana V, De M, Chu S, Jaiswal M, Rotz M, Meade TJ, Dravid VP.

Cancer Treat Res. 2015;166:51-83. doi: 10.1007/978-3-319-16555-4_3. Review.


Nanodiscs as a Modular Platform for Multimodal MR-Optical Imaging.

Carney CE, Lenov IL, Baker CJ, MacRenaris KW, Eckermann AL, Sligar SG, Meade TJ.

Bioconjug Chem. 2015 May 20;26(5):899-905. doi: 10.1021/acs.bioconjchem.5b00107. Epub 2015 Apr 9.


High relaxivity Gd(III)-DNA gold nanostars: investigation of shape effects on proton relaxation.

Rotz MW, Culver KS, Parigi G, MacRenaris KW, Luchinat C, Odom TW, Meade TJ.

ACS Nano. 2015 Mar 24;9(3):3385-96. doi: 10.1021/nn5070953.


Light-activated protein inhibition through photoinduced electron transfer of a ruthenium(II)-cobalt(III) bimetallic complex.

Holbrook RJ, Weinberg DJ, Peterson MD, Weiss EA, Meade TJ.

J Am Chem Soc. 2015 Mar 11;137(9):3379-85. doi: 10.1021/jacs.5b00342. Epub 2015 Mar 2.


Graphene oxide enhances cellular delivery of hydrophilic small molecules by co-incubation.

Hung AH, Holbrook RJ, Rotz MW, Glasscock CJ, Mansukhani ND, MacRenaris KW, Manus LM, Duch MC, Dam KT, Hersam MC, Meade TJ.

ACS Nano. 2014 Oct 28;8(10):10168-77. doi: 10.1021/nn502986e. Epub 2014 Sep 19.


A multimeric MR-optical contrast agent for multimodal imaging.

Harrison VS, Carney CE, Macrenaris KW, Meade TJ.

Chem Commun (Camb). 2014 Oct 9;50(78):11469-71. doi: 10.1039/c4cc05651e.


Progesterone-targeted magnetic resonance imaging probes.

Townsend TR, Moyle-Heyrman G, Sukerkar PA, MacRenaris KW, Burdette JE, Meade TJ.

Bioconjug Chem. 2014 Aug 20;25(8):1428-37. doi: 10.1021/bc500265h. Epub 2014 Jul 25.


Modulation of amyloid-β aggregation by histidine-coordinating Cobalt(III) Schiff base complexes.

Heffern MC, Velasco PT, Matosziuk LM, Coomes JL, Karras C, Ratner MA, Klein WL, Eckermann AL, Meade TJ.

Chembiochem. 2014 Jul 21;15(11):1584-9. doi: 10.1002/cbic.201402201. Epub 2014 Jun 24.


Gd(III)-labeled peptide nanofibers for reporting on biomaterial localization in vivo.

Preslar AT, Parigi G, McClendon MT, Sefick SS, Moyer TJ, Haney CR, Waters EA, MacRenaris KW, Luchinat C, Stupp SI, Meade TJ.

ACS Nano. 2014 Jul 22;8(7):7325-32. doi: 10.1021/nn502393u. Epub 2014 Jun 25. Erratum in: ACS Nano. 2015 Nov 24;9(11):11502.


Cell labeling via membrane-anchored lipophilic MR contrast agents.

Carney CE, MacRenaris KW, Mastarone DJ, Kasjanski DR, Hung AH, Meade TJ.

Bioconjug Chem. 2014 May 21;25(5):945-54. doi: 10.1021/bc500083t. Epub 2014 May 9.


Synthesis and characterization of a porphyrazine-Gd(III) MRI contrast agent and in vivo imaging of a breast cancer xenograft model.

Trivedi ER, Ma Z, Waters EA, Macrenaris KW, Subramanian R, Barrett AG, Meade TJ, Hoffman BM.

Contrast Media Mol Imaging. 2014 Jul-Aug;9(4):313-22. doi: 10.1002/cmmi.1577.


pH-Responsive Theranostic Polymer-Caged Nanobins (PCNs): Enhanced Cytotoxicity and T1 MRI Contrast by Her2-Targeting.

Hong BJ, Swindell EP, Macrenaris KW, Hankins PL, Chipre AJ, Mastarone DJ, Ahn RW, Meade TJ, O'Halloran TV, Nguyen ST.

Part Part Syst Charact. 2013 Sep;30(9):770-774.


Advances and innovations in brain arteriovenous malformation surgery.

Bendok BR, El Tecle NE, El Ahmadieh TY, Koht A, Gallagher TA, Carroll TJ, Markl M, Sabbagha R, Sabbagha A, Cella D, Nowinski C, Dewald JP, Meade TJ, Samson D, Batjer HH.

Neurosurgery. 2014 Feb;74 Suppl 1:S60-73. doi: 10.1227/NEU.0000000000000230. Review.


Lanthanide probes for bioresponsive imaging.

Heffern MC, Matosziuk LM, Meade TJ.

Chem Rev. 2014 Apr 23;114(8):4496-539. doi: 10.1021/cr400477t. Epub 2013 Dec 13. Review. No abstract available.


Mechanisms of Gadographene-Mediated Proton Spin Relaxation.

Hung AH, Duch MC, Parigi G, Rotz MW, Manus LM, Mastarone DJ, Dam KT, Gits CC, Macrenaris KW, Luchinat C, Hersam MC, Meade TJ.

J Phys Chem C Nanomater Interfaces. 2013 Aug 8;117(31). doi: 10.1021/jp406909b.


High dynamic range processing for magnetic resonance imaging.

Hung AH, Liang T, Sukerkar PA, Meade TJ.

PLoS One. 2013 Nov 8;8(11):e77883. doi: 10.1371/journal.pone.0077883. eCollection 2013.


Spectroscopic elucidation of the inhibitory mechanism of Cys2His2 zinc finger transcription factors by cobalt(III) Schiff base complexes.

Heffern MC, Kurutz JW, Meade TJ.

Chemistry. 2013 Dec 9;19(50):17043-53. doi: 10.1002/chem.201301659. Epub 2013 Nov 6.


Preface for the forum on metals in medicine and health: new opportunities and approaches to improving health.

Crans DC, Meade TJ.

Inorg Chem. 2013 Nov 4;52(21):12181-3. doi: 10.1021/ic402341n. No abstract available.


Spherical nucleic acid nanoparticle conjugates as an RNAi-based therapy for glioblastoma.

Jensen SA, Day ES, Ko CH, Hurley LA, Luciano JP, Kouri FM, Merkel TJ, Luthi AJ, Patel PC, Cutler JI, Daniel WL, Scott AW, Rotz MW, Meade TJ, Giljohann DA, Mirkin CA, Stegh AH.

Sci Transl Med. 2013 Oct 30;5(209):209ra152. doi: 10.1126/scitranslmed.3006839.


Multimodal imaging enables early detection and characterization of changes in tumor permeability of brain metastases.

Thorsen F, Fite B, Mahakian LM, Seo JW, Qin S, Harrison V, Johnson S, Ingham E, Caskey C, Sundstrøm T, Meade TJ, Harter PN, Skaftnesmo KO, Ferrara KW.

J Control Release. 2013 Dec 28;172(3):812-22. doi: 10.1016/j.jconrel.2013.10.019. Epub 2013 Oct 29.


Pillar[5]arene as a co-factor in templating rotaxane formation.

Ke C, Strutt NL, Li H, Hou X, Hartlieb KJ, McGonigal PR, Ma Z, Iehl J, Stern CL, Cheng C, Zhu Z, Vermeulen NA, Meade TJ, Botros YY, Stoddart JF.

J Am Chem Soc. 2013 Nov 13;135(45):17019-30. doi: 10.1021/ja407229h. Epub 2013 Oct 30.


PSA enzymatic activity: a new biomarker for assessing prostate cancer aggressiveness.

Ahrens MJ, Bertin PA, Vonesh EF, Meade TJ, Catalona WJ, Georganopoulou D.

Prostate. 2013 Dec;73(16):1731-7. doi: 10.1002/pros.22714. Epub 2013 Aug 9.


Photoinduced electron transfer from PbS quantum dots to cobalt(III) Schiff base complexes: light activation of a protein inhibitor.

Peterson MD, Holbrook RJ, Meade TJ, Weiss EA.

J Am Chem Soc. 2013 Sep 4;135(35):13162-7. doi: 10.1021/ja4065393. Epub 2013 Aug 23.


Structural optimization of Zn(II)-activated magnetic resonance imaging probes.

Matosziuk LM, Leibowitz JH, Heffern MC, MacRenaris KW, Ratner MA, Meade TJ.

Inorg Chem. 2013 Nov 4;52(21):12250-61. doi: 10.1021/ic400681j. Epub 2013 Jun 18.


Extending the distance range accessed with continuous wave EPR with Gd3+ spin probes at high magnetic fields.

Edwards DT, Ma Z, Meade TJ, Goldfarb D, Han S, Sherwin MS.

Phys Chem Chem Phys. 2013 Jul 21;15(27):11313-26. doi: 10.1039/c3cp43787f. Epub 2013 Jun 4.


Optimization of pulsed DEER measurements for Gd-based labels: choice of operational frequencies, pulse durations and positions, and temperature.

Raitsimring A, Astashkin AV, Enemark JH, Kaminker I, Goldfarb D, Walter ED, Song Y, Meade TJ.

Appl Magn Reson. 2013 Jun;44(6):649-670.


Synthesis, Characterization, and in vitro Testing of a Bacteria-Targeted MR Contrast Agent.

Matosziuk LM, Harney AS, Macrenaris KW, Meade TJ.

Eur J Inorg Chem. 2012 Apr;2012(12):2099-2107.


Dielectric Resonator for Ka-Band Pulsed EPR Measurements at Cryogenic Temperatures: Probehead Construction and Applications.

Raitsimring A, Astashkin A, Enemark JH, Blank A, Twig Y, Song Y, Meade TJ.

Appl Magn Reson. 2012 Jun 1;42(4):441-452.


Rational design of [Co(acacen)L2]+ inhibitors of protein function.

Matosziuk LM, Holbrook RJ, Manus LM, Heffern MC, Ratner MA, Meade TJ.

Dalton Trans. 2013 Mar 21;42(11):4002-12. doi: 10.1039/c2dt32565a. Epub 2013 Jan 22.


Axial ligand exchange of N-heterocyclic cobalt(III) Schiff base complexes: molecular structure and NMR solution dynamics.

Manus LM, Holbrook RJ, Atesin TA, Heffern MC, Harney AS, Eckermann AL, Meade TJ.

Inorg Chem. 2013 Jan 18;52(2):1069-76. doi: 10.1021/ic302379j. Epub 2013 Jan 2.

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