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Items: 1 to 50 of 76

1.

Mouse Models for Use in Cryptosporidium Infection Studies and Quantification of Parasite Burden Using Flow Cytometry, qPCR, and Histopathology.

Sonzogni-Desautels K, Mead JR, Ndao M.

Methods Mol Biol. 2020;2052:229-251. doi: 10.1007/978-1-4939-9748-0_14.

PMID:
31452166
2.

Inflammasome components caspase-1 and adaptor protein apoptosis-associated speck-like proteins are important in resistance to Cryptosporidium parvum.

McNair NN, Bedi C, Shayakhmetov DM, Arrowood MJ, Mead JR.

Microbes Infect. 2018 Jun - Jul;20(6):369-375. doi: 10.1016/j.micinf.2018.04.006. Epub 2018 May 26.

PMID:
29842985
3.

The Existing Drug Vorinostat as a New Lead Against Cryptosporidiosis by Targeting the Parasite Histone Deacetylases.

Guo F, Zhang H, McNair NN, Mead JR, Zhu G.

J Infect Dis. 2018 Mar 13;217(7):1110-1117. doi: 10.1093/infdis/jix689.

4.

Auranofin and N-heterocyclic carbene gold-analogs are potent inhibitors of the bacteria Helicobacter pylori.

Owings JP, McNair NN, Mui YF, Gustafsson TN, Holmgren A, Contel M, Goldberg JB, Mead JR.

FEMS Microbiol Lett. 2016 Jul;363(14). pii: fnw148. doi: 10.1093/femsle/fnw148. Epub 2016 Jun 7.

PMID:
27279627
5.

A review of the global burden, novel diagnostics, therapeutics, and vaccine targets for cryptosporidium.

Checkley W, White AC Jr, Jaganath D, Arrowood MJ, Chalmers RM, Chen XM, Fayer R, Griffiths JK, Guerrant RL, Hedstrom L, Huston CD, Kotloff KL, Kang G, Mead JR, Miller M, Petri WA Jr, Priest JW, Roos DS, Striepen B, Thompson RC, Ward HD, Van Voorhis WA, Xiao L, Zhu G, Houpt ER.

Lancet Infect Dis. 2015 Jan;15(1):85-94. doi: 10.1016/S1473-3099(14)70772-8. Epub 2014 Sep 29. Review.

6.

IL-18 cytokine levels modulate innate immune responses and cryptosporidiosis in mice.

Bedi B, McNair NN, Förster I, Mead JR.

J Eukaryot Microbiol. 2015 Jan-Feb;62(1):44-50. doi: 10.1111/jeu.12164. Epub 2014 Oct 23.

PMID:
25155632
7.

Prospects for immunotherapy and vaccines against Cryptosporidium.

Mead JR.

Hum Vaccin Immunother. 2014;10(6):1505-13. doi: 10.4161/hv.28485. Epub 2014 Mar 17. Review.

8.

Validation of IMP dehydrogenase inhibitors in a mouse model of cryptosporidiosis.

Gorla SK, McNair NN, Yang G, Gao S, Hu M, Jala VR, Haribabu B, Striepen B, Cuny GD, Mead JR, Hedstrom L.

Antimicrob Agents Chemother. 2014;58(3):1603-14. doi: 10.1128/AAC.02075-13. Epub 2013 Dec 23.

9.

Dendritic cells play a role in host susceptibility to Cryptosporidium parvum infection.

Bedi B, McNair NN, Mead JR.

Immunol Lett. 2014 Mar-Apr;158(1-2):42-51. doi: 10.1016/j.imlet.2013.11.015. Epub 2013 Dec 1.

PMID:
24295591
10.

Amelioration of Cryptosporidium parvum infection in vitro and in vivo by targeting parasite fatty acyl-coenzyme A synthetases.

Guo F, Zhang H, Fritzler JM, Rider SD Jr, Xiang L, McNair NN, Mead JR, Zhu G.

J Infect Dis. 2014 Apr 15;209(8):1279-87. doi: 10.1093/infdis/jit645. Epub 2013 Nov 23.

11.

Discovery of sialyl Lewis A and Lewis X modified protein cancer biomarkers using high density antibody arrays.

Rho JH, Mead JR, Wright WS, Brenner DE, Stave JW, Gildersleeve JC, Lampe PD.

J Proteomics. 2014 Jan 16;96:291-9. doi: 10.1016/j.jprot.2013.10.030. Epub 2013 Nov 1.

12.

Microarray analysis of the human antibody response to synthetic Cryptosporidium glycopeptides.

Heimburg-Molinaro J, Priest JW, Live D, Boons GJ, Song X, Cummings RD, Mead JR.

Int J Parasitol. 2013 Oct;43(11):901-7. doi: 10.1016/j.ijpara.2013.05.012. Epub 2013 Jul 12.

13.

CD4⁺ effector and memory cell populations protect against Cryptosporidium parvum infection.

McNair NN, Mead JR.

Microbes Infect. 2013 Jul-Aug;15(8-9):599-606. doi: 10.1016/j.micinf.2013.04.009. Epub 2013 May 2.

PMID:
23644177
14.

Phthalazinone inhibitors of inosine-5'-monophosphate dehydrogenase from Cryptosporidium parvum.

Johnson CR, Gorla SK, Kavitha M, Zhang M, Liu X, Striepen B, Mead JR, Cuny GD, Hedstrom L.

Bioorg Med Chem Lett. 2013 Feb 15;23(4):1004-7. doi: 10.1016/j.bmcl.2012.12.037. Epub 2012 Dec 27.

15.

Cryptosporidium parvum antigens induce mouse and human dendritic cells to generate Th1-enhancing cytokines.

Bedi B, Mead JR.

Parasite Immunol. 2012 Oct;34(10):473-85. doi: 10.1111/j.1365-3024.2012.01382.x.

16.

Evaluation of DNA encoding acidic ribosomal protein P2 of Cryptosporidium parvum as a potential vaccine candidate for cryptosporidiosis.

Benitez A, Priest JW, Ehigiator HN, McNair N, Mead JR.

Vaccine. 2011 Nov 15;29(49):9239-45. doi: 10.1016/j.vaccine.2011.09.094. Epub 2011 Oct 1.

17.

Cloning and characterization of the acidic ribosomal protein P2 of Cryptosporidium parvum, a new 17-kilodalton antigen.

Priest JW, Kwon JP, Montgomery JM, Bern C, Moss DM, Freeman AR, Jones CC, Arrowood MJ, Won KY, Lammie PJ, Gilman RH, Mead JR.

Clin Vaccine Immunol. 2010 Jun;17(6):954-65. doi: 10.1128/CVI.00073-10. Epub 2010 Apr 21.

18.

Challenges and prospects for a Cryptosporidium vaccine.

Mead JR.

Future Microbiol. 2010 Mar;5(3):335-7. doi: 10.2217/fmb.09.115. No abstract available.

19.
20.

Functional characterization of the nucleotide binding domain of the Cryptosporidium parvum CpABC4 transporter: an iron-sulfur cluster transporter homolog.

Benitez AJ, Arrowood MJ, Mead JR.

Mol Biochem Parasitol. 2009 Jun;165(2):103-10. doi: 10.1016/j.molbiopara.2009.01.010. Epub 2009 Jan 30.

PMID:
19428657
21.

Induction of murine immune responses by DNA encoding a 23-kDa antigen of Cryptosporidium parvum.

Ehigiator HN, Romagnoli P, Priest JW, Secor WE, Mead JR.

Parasitol Res. 2007 Sep;101(4):943-50. Epub 2007 May 9.

PMID:
17487508
22.

Summary of research presentations on Cryptosporidium.

Mead JR.

J Eukaryot Microbiol. 2006;53 Suppl 1:S20-1. No abstract available.

PMID:
17169055
23.

The International Workshops on Opportunistic Protists.

Kaneshiro ES, Cali A, Cushion MT, Lindsay DS, Marciano-Cabral F, Mead JR, Weiss LM.

J Eukaryot Microbiol. 2006;53 Suppl 1:S1-7. No abstract available.

PMID:
17169013
24.

Cryptosporidium parvum: the contribution of Th1-inducing pathways to the resolution of infection in mice.

Ehigiator HN, McNair N, Mead JR.

Exp Parasitol. 2007 Feb;115(2):107-13. Epub 2006 Aug 22.

PMID:
16920103
25.

Use of Trichomonas vaginalis clinical isolates to evaluate correlation of gene expression and metronidazole resistance.

Mead JR, Fernadez M, Romagnoli PA, Secor WE.

J Parasitol. 2006 Feb;92(1):196-9.

PMID:
16629339
26.

Mucosal cytokine and antigen-specific responses to Cryptosporidium parvum in IL-12p40 KO mice.

Ehigiator HN, Romagnoli P, Borgelt K, Fernandez M, McNair N, Secor WE, Mead JR.

Parasite Immunol. 2005 Jan-Feb;27(1-2):17-28.

27.
28.

Cryptosporidium parvum: effect of multi-drug reversing agents on the expression and function of ATP-binding cassette transporters.

Bonafonte MT, Romagnoli PA, McNair N, Shaw AP, Scanlon M, Leitch GJ, Mead JR.

Exp Parasitol. 2004 Mar-Apr;106(3-4):126-34.

PMID:
15172220
29.

Efficacy of glycoconjugated dinitroanilines against Cryptosporidium parvum.

Mead JR, Fauq AH, Khan MA, McNair N.

J Eukaryot Microbiol. 2003;50 Suppl:550-2. No abstract available.

PMID:
14736158
30.

IL-12 knockout C57BL/6 mice are protected from re-infection with Cryptosporidium parvum after challenge.

Ehigiator HN, McNair N, Mead JR.

J Eukaryot Microbiol. 2003;50 Suppl:539-41. No abstract available.

PMID:
14736155
31.

Workshop summary of Cryptosporidium research from the VIII International Workshop on Opportunistic Protists (IWOP-8).

Mead JR.

J Eukaryot Microbiol. 2003;50 Suppl:527-8. No abstract available.

PMID:
14736151
33.

Lipoprotein lipase: structure, function, regulation, and role in disease.

Mead JR, Irvine SA, Ramji DP.

J Mol Med (Berl). 2002 Dec;80(12):753-69. Epub 2002 Oct 24. Review.

PMID:
12483461
34.

Susceptibility to Cryptosporidium parvum infections in cytokine- and chemokine-receptor knockout mice.

Campbell LD, Stewart JN, Mead JR.

J Parasitol. 2002 Oct;88(5):1014-6.

PMID:
12435147
35.

Comparison of in vitro cell culture and a mouse assay for measuring infectivity of Cryptosporidium parvum.

Rochelle PA, Marshall MM, Mead JR, Johnson AM, Korich DG, Rosen JS, De Leon R.

Appl Environ Microbiol. 2002 Aug;68(8):3809-17.

36.

Cryptosporidiosis and the challenges of chemotherapy.

Mead JR.

Drug Resist Updat. 2002 Feb;5(1):47-57. Review.

PMID:
12127863
37.

The pivotal role of lipoprotein lipase in atherosclerosis.

Mead JR, Ramji DP.

Cardiovasc Res. 2002 Aug 1;55(2):261-9. Review. No abstract available.

PMID:
12123765
38.

Cryptosporidium research 2001: workshop summary.

Mead JR.

J Eukaryot Microbiol. 2001;Suppl:15S-16S. No abstract available.

PMID:
11906042
39.

Identification of two putative ATP-cassette genes in Encephalitozoon intestinalis.

Bonafonte MT, Stewart J, Mead JR.

Int J Parasitol. 2001 Dec;31(14):1681-5.

PMID:
11730796
40.

Exogenous interleukin-12 (IL-12) exacerbates Cryptosporidium parvum infection in gamma interferon knockout mice.

Smith LM, Bonafonte MT, Campbell LD, Mead JR.

Exp Parasitol. 2001 Jul;98(3):123-33.

PMID:
11527435
41.

Human T and B cell immunoreactivity to a recombinant 23-kDa Cryptosporidium parvum antigen.

Smith LM, Priest JW, Lammie PJ, Mead JR.

J Parasitol. 2001 Jun;87(3):704-7.

PMID:
11426740
43.
44.

Cryptosporidium andersoni n. sp. (Apicomplexa: Cryptosporiidae) from cattle, Bos taurus.

Lindsay DS, Upton SJ, Owens DS, Morgan UM, Mead JR, Blagburn BL.

J Eukaryot Microbiol. 2000 Jan-Feb;47(1):91-5.

PMID:
10651302
45.

Lipoprotein lipase, a key role in atherosclerosis?

Mead JR, Cryer A, Ramji DP.

FEBS Lett. 1999 Nov 26;462(1-2):1-6. Review.

46.

Improved efficacy of dinitroaniline analogs for use as anti-cryptosporidial drugs.

Mead JR, Benbow JW, Garmon D, Stewart J.

J Eukaryot Microbiol. 1999 Sep-Oct;46(5):62S-63S. No abstract available.

PMID:
10519250
47.

Recent trends in Cryptosporidium research: workshop summary.

Mead JR.

J Eukaryot Microbiol. 1999 Sep-Oct;46(5):38S-39S. No abstract available.

PMID:
10519239
48.

Characterization of an alpha-tubulin gene of Cryptosporidium parvum.

Bonafonte MT, Garmon D, Mead JR.

J Eukaryot Microbiol. 1999 Sep-Oct;46(5):545-7.

PMID:
10519222
49.
50.

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