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Items: 11

1.

Discovery and Validation of Pyridoxic Acid and Homovanillic Acid as Novel Endogenous Plasma Biomarkers of Organic Anion Transporter (OAT) 1 and OAT3 in Cynomolgus Monkeys.

Shen H, Nelson DM, Oliveira RV, Zhang Y, Mcnaney CA, Gu X, Chen W, Su C, Reily MD, Shipkova PA, Gan J, Lai Y, Marathe P, Humphreys WG.

Drug Metab Dispos. 2018 Feb;46(2):178-188. doi: 10.1124/dmd.117.077586. Epub 2017 Nov 21.

PMID:
29162614
2.

Beyond classical derivatization: analyte 'derivatives' in the bioanalysis of endogenous and exogenous compounds.

Barnaby OS, Benitex Y, Cantone JL, McNaney CA, Olah TV, Drexler DM.

Bioanalysis. 2015 Oct;7(19):2501-13. doi: 10.4155/bio.15.171. Epub 2015 Oct 15.

PMID:
26466806
3.

Bioanalysis of acetylcarnitine in cerebrospinal fluid by HILIC-mass spectrometry.

Holder BR, McNaney CA, Luchetti D, Schaeffer E, Drexler DM.

Biomed Chromatogr. 2015 Sep;29(9):1375-9. doi: 10.1002/bmc.3433. Epub 2015 Feb 24.

PMID:
25712252
4.

Labware additives identified to be selective monoamine oxidase-B inhibitors.

Stewart J, Drexler DM, Leet JE, McNaney CA, Herbst JJ.

J Biomol Screen. 2014 Dec;19(10):1409-14. doi: 10.1177/1087057114551523. Epub 2014 Oct 8.

PMID:
25296658
5.

Bioanalysis of (1R,4R,5S,6R)-4-amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid (LY379268) in rat plasma using derivatization liquid chromatography/mass spectrometry.

Benitex Y, Luan FN, Shields E, McNaney CA, Morgan DG, Olah TV, Drexler DM.

Bioanalysis. 2014;6(14):1901-5. doi: 10.4155/bio.14.103.

PMID:
25158962
6.

Analysis of L-serine-O-phosphate in cerebrospinal spinal fluid by derivatization-liquid chromatography/mass spectrometry.

McNaney CA, Benitex Y, Luchetti D, Labasi JM, Olah TV, Morgan DG, Drexler DM.

Anal Biochem. 2014 May 1;452:10-2. doi: 10.1016/j.ab.2014.02.007. Epub 2014 Feb 15.

PMID:
24534252
7.

Addressing the need for biomarker liquid chromatography/mass spectrometry assays: a protocol for effective method development for the bioanalysis of endogenous compounds in cerebrospinal fluid.

Benitex Y, McNaney CA, Luchetti D, Schaeffer E, Olah TV, Morgan DG, Drexler DM.

Rapid Commun Mass Spectrom. 2013 Aug 30;27(16):1882-6. doi: 10.1002/rcm.6639.

PMID:
23857934
8.

Metabolomic and transcriptomic changes induced by overnight (16 h) fasting in male and female Sprague-Dawley rats.

Robertson DG, Ruepp SU, Stryker SA, Hnatyshyn SY, Shipkova PA, Aranibar N, Mcnaney CA, Fiehn O, Reily MD.

Chem Res Toxicol. 2011 Apr 18;24(4):481-7. doi: 10.1021/tx200074f. Epub 2011 Mar 25.

PMID:
21381695
9.

An automated liquid chromatography-mass spectrometry process to determine metabolic stability half-life and intrinsic clearance of drug candidates by substrate depletion.

McNaney CA, Drexler DM, Hnatyshyn SY, Zvyaga TA, Knipe JO, Belcastro JV, Sanders M.

Assay Drug Dev Technol. 2008 Feb;6(1):121-9. doi: 10.1089/adt.2007.103.

PMID:
18336089
10.

An automated high throughput liquid chromatography-mass spectrometry process to assess the metabolic stability of drug candidates.

Drexler DM, Belcastro JV, Dickinson KE, Edinger KJ, Hnatyshyn SY, Josephs JL, Langish RA, McNaney CA, Santone KS, Shipkova PA, Tymiak AA, Zvyaga TA, Sanders M.

Assay Drug Dev Technol. 2007 Apr;5(2):247-64.

PMID:
17477833
11.

Simultaneous determination of tacrine and 1-hydroxy-, 2-hydroxy-, and 4-hydroxytacrine in human plasma by high-performance liquid chromatography with fluorescence detection.

Haughey DB, McNaney CA, Collis MS, Brown RR, Siedlik PH, Balogh L, Klockowski PM.

J Pharm Sci. 1994 Nov;83(11):1582-5.

PMID:
7891279

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