Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 109


Mapping the drivers of within-host pathogen evolution using massive data sets.

Palmer DS, Turner I, Fidler S, Frater J, Goedhals D, Goulder P, Huang KG, Oxenius A, Phillips R, Shapiro R, Vuuren CV, McLean AR, McVean G.

Nat Commun. 2019 Jul 9;10(1):3017. doi: 10.1038/s41467-019-10724-w.


Metabolic implications of exposure to wastewater effluent in bluegill sunfish.

Du SNN, Choi JA, McCallum ES, McLean AR, Borowiec BG, Balshine S, Scott GR.

Comp Biochem Physiol C Toxicol Pharmacol. 2019 Oct;224:108562. doi: 10.1016/j.cbpc.2019.108562. Epub 2019 Jun 26.


A restatement of the natural science evidence base on the effects of endocrine disrupting chemicals on wildlife.

Godfray HCJ, Stephens AEA, Jepson PD, Jobling S, Johnson AC, Matthiessen P, Sumpter JP, Tyler CR, McLean AR.

Proc Biol Sci. 2019 Feb 27;286(1897):20182416. doi: 10.1098/rspb.2018.2416.


Tragedy revisited.

Boyd R, Richerson PJ, Meinzen-Dick R, De Moor T, Jackson MO, Gjerde KM, Harden-Davies H, Frischmann BM, Madison MJ, Strandburg KJ, McLean AR, Dye C.

Science. 2018 Dec 14;362(6420):1236-1241. doi: 10.1126/science.aaw0911. Epub 2018 Dec 13. No abstract available.


Malaria elimination in remote communities requires integration of malaria control activities into general health care: an observational study and interrupted time series analysis in Myanmar.

McLean ARD, Wai HP, Thu AM, Khant ZS, Indrasuta C, Ashley EA, Kyaw TT, Day NPJ, Dondorp A, White NJ, Smithuis FM.

BMC Med. 2018 Oct 22;16(1):183. doi: 10.1186/s12916-018-1172-x.


Increased T cell trafficking as adjunct therapy for HIV-1.

Fryer HR, Wolinsky SM, McLean AR.

PLoS Comput Biol. 2018 Mar 2;14(3):e1006028. doi: 10.1371/journal.pcbi.1006028. eCollection 2018 Mar.


Investigating the effects of age-related spatial structuring on the transmission of a tick-borne virus in a colonially breeding host.

Wanelik KM, Burthe SJ, Harris MP, Nunn MA, Godfray HCJ, Sheldon BC, McLean AR, Wanless S.

Ecol Evol. 2017 Nov 12;7(24):10930-10940. doi: 10.1002/ece3.3612. eCollection 2017 Dec.


Lorenzo-Redondo et al. reply.

Lorenzo-Redondo R, Fryer HR, Bedford T, Kim EY, Archer J, Pond SLK, Chung YS, Penugonda S, Chipman JG, Fletcher CV, Schacker TW, Malim MH, Rambaut A, Haase AT, McLean AR, Wolinsky SM.

Nature. 2017 Nov 22;551(7681):E10. doi: 10.1038/nature24635. No abstract available.


P. falciparum infection and maternofetal antibody transfer in malaria-endemic settings of varying transmission.

McLean ARD, Stanisic D, McGready R, Chotivanich K, Clapham C, Baiwog F, Pimanpanarak M, Siba P, Mueller I, King CL, Nosten F, Beeson JG, Rogerson S, Simpson JA, Fowkes FJI.

PLoS One. 2017 Oct 13;12(10):e0186577. doi: 10.1371/journal.pone.0186577. eCollection 2017.


A restatement of the natural science evidence base concerning the health effects of low-level ionizing radiation.

McLean AR, Adlen EK, Cardis E, Elliott A, Goodhead DT, Harms-Ringdahl M, Hendry JH, Hoskin P, Jeggo PA, Mackay DJC, Muirhead CR, Shepherd J, Shore RE, Thomas GA, Wakeford R, Godfray HCJ.

Proc Biol Sci. 2017 Sep 13;284(1862). pii: 20171070. doi: 10.1098/rspb.2017.1070. Review.


Evolution, human-microbe interactions, and life history plasticity.

Rook G, Bäckhed F, Levin BR, McFall-Ngai MJ, McLean AR.

Lancet. 2017 Jul 29;390(10093):521-530. doi: 10.1016/S0140-6736(17)30566-4. Epub 2017 Jul 27. Review.


External Defibrillator Damage Associated With Attempted Synchronized Dual-Dose Cardioversion.

Gerstein NS, McLean AR, Stecker EC, Schulman PM.

Ann Emerg Med. 2018 Jan;71(1):109-112. doi: 10.1016/j.annemergmed.2017.04.005. Epub 2017 May 27.


Antibody Responses to Plasmodium falciparum and Plasmodium vivax and Prospective Risk of Plasmodium spp. Infection Postpartum.

McLean ARD, Boel M, McGready R, Ataide R, Drew D, Tsuboi T, Beeson JG, Nosten F, Simpson JA, Fowkes FJI.

Am J Trop Med Hyg. 2017 May;96(5):1197-1204. doi: 10.4269/ajtmh.16-0690.


Antibody responses to Plasmodium falciparum and Plasmodium vivax blood-stage and sporozoite antigens in the postpartum period.

McLean AR, Boel ME, McGready R, Ataide R, Drew D, Tsuboi T, Beeson JG, Nosten F, Simpson JA, Fowkes FJ.

Sci Rep. 2016 Aug 25;6:32159. doi: 10.1038/srep32159.


Persistent HIV-1 replication maintains the tissue reservoir during therapy.

Lorenzo-Redondo R, Fryer HR, Bedford T, Kim EY, Archer J, Pond SLK, Chung YS, Penugonda S, Chipman J, Fletcher CV, Schacker TW, Malim MH, Rambaut A, Haase AT, McLean AR, Wolinsky SM.

Nature. 2016 Feb 4;530(7588):51-56. doi: 10.1038/nature16933. Epub 2016 Jan 27.


The impact of antiretroviral therapy on population-level virulence evolution of HIV-1.

Roberts HE, Goulder PJ, McLean AR.

J R Soc Interface. 2015 Dec 6;12(113):20150888. doi: 10.1098/rsif.2015.0888.


A restatement of recent advances in the natural science evidence base concerning neonicotinoid insecticides and insect pollinators.

Godfray HC, Blacquière T, Field LM, Hails RS, Potts SG, Raine NE, Vanbergen AJ, McLean AR.

Proc Biol Sci. 2015 Nov 7;282(1818):20151821. doi: 10.1098/rspb.2015.1821. Review.


Seven challenges in modeling pathogen dynamics within-host and across scales.

Gog JR, Pellis L, Wood JL, McLean AR, Arinaminpathy N, Lloyd-Smith JO.

Epidemics. 2015 Mar;10:45-8. doi: 10.1016/j.epidem.2014.09.009. Epub 2014 Sep 30.


Nine challenges in modelling the emergence of novel pathogens.

Lloyd-Smith JO, Funk S, McLean AR, Riley S, Wood JL.

Epidemics. 2015 Mar;10:35-9. doi: 10.1016/j.epidem.2014.09.002. Epub 2014 Sep 19.


Five challenges in modelling interacting strain dynamics.

Wikramaratna PS, Kucharski A, Gupta S, Andreasen V, McLean AR, Gog JR.

Epidemics. 2015 Mar;10:31-4. doi: 10.1016/j.epidem.2014.07.005. Epub 2014 Oct 7.


Malaria and immunity during pregnancy and postpartum: a tale of two species.

McLean AR, Ataide R, Simpson JA, Beeson JG, Fowkes FJ.

Parasitology. 2015 Jul;142(8):999-1015. doi: 10.1017/S0031182015000074. Epub 2015 Mar 3. Review.


Structured observations reveal slow HIV-1 CTL escape.

Roberts HE, Hurst J, Robinson N, Brown H, Flanagan P, Vass L, Fidler S, Weber J, Babiker A, Phillips RE, McLean AR, Frater J; SPARTAC trial investigators.

PLoS Genet. 2015 Feb 2;11(2):e1004914. doi: 10.1371/journal.pgen.1004914. eCollection 2015 Feb.


Impact of HLA-driven HIV adaptation on virulence in populations of high HIV seroprevalence.

Payne R, Muenchhoff M, Mann J, Roberts HE, Matthews P, Adland E, Hempenstall A, Huang KH, Brockman M, Brumme Z, Sinclair M, Miura T, Frater J, Essex M, Shapiro R, Walker BD, Ndung'u T, McLean AR, Carlson JM, Goulder PJ.

Proc Natl Acad Sci U S A. 2014 Dec 16;111(50):E5393-400. doi: 10.1073/pnas.1413339111. Epub 2014 Dec 1.


Positive selection and compensatory adaptation interact to stabilize non-transmissible plasmids.

San Millan A, Peña-Miller R, Toll-Riera M, Halbert ZV, McLean AR, Cooper BS, MacLean RC.

Nat Commun. 2014 Oct 10;5:5208. doi: 10.1038/ncomms6208.


A restatement of the natural science evidence base concerning neonicotinoid insecticides and insect pollinators.

Godfray HC, Blacquière T, Field LM, Hails RS, Petrokofsky G, Potts SG, Raine NE, Vanbergen AJ, McLean AR.

Proc Biol Sci. 2014 Jul 7;281(1786). pii: 20140558. doi: 10.1098/rspb.2014.0558. Review.


Epidemiology. Coming to an airport near you.

McLean AR.

Science. 2013 Dec 13;342(6164):1330-1. doi: 10.1126/science.1247830. No abstract available.


A restatement of the natural science evidence base relevant to the control of bovine tuberculosis in Great Britain.

Godfray HC, Donnelly CA, Kao RR, Macdonald DW, McDonald RA, Petrokofsky G, Wood JL, Woodroffe R, Young DB, McLean AR.

Proc Biol Sci. 2013 Aug 7;280(1768):20131634. doi: 10.1098/rspb.2013.1634. Print 2013 Oct 7.


Towards the endgame and beyond: complexities and challenges for the elimination of infectious diseases.

Klepac P, Metcalf CJ, McLean AR, Hampson K.

Philos Trans R Soc Lond B Biol Sci. 2013 Jun 24;368(1623):20120137. doi: 10.1098/rstb.2012.0137. Print 2013 Aug 5.


Integrating genealogical and dynamical modelling to infer escape and reversion rates in HIV epitopes.

Palmer D, Frater J, Phillips R, McLean AR, McVean G.

Proc Biol Sci. 2013 May 15;280(1762):20130696. doi: 10.1098/rspb.2013.0696. Print 2013 Jul 7.


Cytotoxic T-lymphocyte escape mutations identified by HLA association favor those which escape and revert rapidly.

Fryer HR, Frater J, Duda A, Palmer D, Phillips RE, McLean AR.

J Virol. 2012 Aug;86(16):8568-80. doi: 10.1128/JVI.07020-11. Epub 2012 Jun 6.


Why was the 2009 influenza pandemic in England so small?

Kubiak RJ, McLean AR.

PLoS One. 2012;7(2):e30223. doi: 10.1371/journal.pone.0030223. Epub 2012 Feb 10.


Utility of routine follow-up head CT scanning after mild traumatic brain injury: a systematic review of the literature.

Stippler M, Smith C, McLean AR, Carlson A, Morley S, Murray-Krezan C, Kraynik J, Kennedy G.

Emerg Med J. 2012 Jul;29(7):528-32. doi: 10.1136/emermed-2011-200162. Epub 2012 Feb 3. Review.


Modelling the spread of HIV immune escape mutants in a vaccinated population.

Fryer HR, McLean AR.

PLoS Comput Biol. 2011 Dec;7(12):e1002289. doi: 10.1371/journal.pcbi.1002289. Epub 2011 Dec 1.


Athena SWAN awards: Bridging the gender gap in UK science.

Donald A, Harvey PH, McLean AR.

Nature. 2011 Oct 5;478(7367):36. doi: 10.1038/478036b. No abstract available.


There is no safe dose of prions.

Fryer HR, McLean AR.

PLoS One. 2011;6(8):e23664. doi: 10.1371/journal.pone.0023664. Epub 2011 Aug 15.


A mathematical framework for estimating pathogen transmission fitness and inoculum size using data from a competitive mixtures animal model.

McCaw JM, Arinaminpathy N, Hurt AC, McVernon J, McLean AR.

PLoS Comput Biol. 2011 Apr;7(4):e1002026. doi: 10.1371/journal.pcbi.1002026. Epub 2011 Apr 28.


Modelling the evolution and spread of HIV immune escape mutants.

Fryer HR, Frater J, Duda A, Roberts MG; SPARTAC Trial Investigators, Phillips RE, McLean AR.

PLoS Pathog. 2010 Nov 18;6(11):e1001196. doi: 10.1371/journal.ppat.1001196.


Dynamic coinfection with multiple viral subtypes in acute hepatitis C.

Smith JA, Aberle JH, Fleming VM, Ferenci P, Thomson EC, Karayiannis P, McLean AR, Holzmann H, Klenerman P.

J Infect Dis. 2010 Dec 15;202(12):1770-9. doi: 10.1086/657317. Epub 2010 Nov 10.


Low rate of delayed deterioration requiring surgical treatment in patients transferred to a tertiary care center for mild traumatic brain injury.

Carlson AP, Ramirez P, Kennedy G, McLean AR, Murray-Krezan C, Stippler M.

Neurosurg Focus. 2010 Nov;29(5):E3. doi: 10.3171/2010.8.FOCUS10182.


Ultrasound determination of chest wall thickness: implications for needle thoracostomy.

McLean AR, Richards ME, Crandall CS, Marinaro JL.

Am J Emerg Med. 2011 Nov;29(9):1173-7. doi: 10.1016/j.ajem.2010.06.030. Epub 2010 Oct 13.


Insights into the evolution and emergence of a novel infectious disease.

Kubiak RJ, Arinaminpathy N, McLean AR.

PLoS Comput Biol. 2010 Sep 30;6(9). pii: e1000947. doi: 10.1371/journal.pcbi.1000947.


Assessing the viral fitness of oseltamivir-resistant influenza viruses in ferrets, using a competitive-mixtures model.

Hurt AC, Nor'e SS, McCaw JM, Fryer HR, Mosse J, McLean AR, Barr IG.

J Virol. 2010 Sep;84(18):9427-38. doi: 10.1128/JVI.00373-10. Epub 2010 Jul 14.


How fast could HIV change gene frequencies in the human population?

Cromer D, Wolinsky SM, McLean AR.

Proc Biol Sci. 2010 Jul 7;277(1690):1981-9. doi: 10.1098/rspb.2009.2073. Epub 2010 Mar 10.


No evidence for competition between cytotoxic T-lymphocyte responses in HIV-1 infection.

Fryer HR, Scherer A, Oxenius A, Phillips R, McLean AR.

Proc Biol Sci. 2009 Dec 22;276(1677):4389-97. doi: 10.1098/rspb.2009.1232. Epub 2009 Sep 23.


The effect of intrinsic stochasticity on transmitted HIV drug resistance patterns.

Marks AJ, Pillay D, McLean AR.

J Theor Biol. 2010 Jan 7;262(1):1-13. doi: 10.1016/j.jtbi.2009.09.017. Epub 2009 Sep 17.


Evolution and emergence of novel human infections.

Arinaminpathy N, McLean AR.

Proc Biol Sci. 2009 Nov 22;276(1675):3937-43. doi: 10.1098/rspb.2009.1059. Epub 2009 Aug 19.


Logistics of control for an influenza pandemic.

Arinaminpathy N, McLean AR.

Epidemics. 2009 Jun;1(2):83-8. doi: 10.1016/j.epidem.2009.04.001. Epub 2009 Apr 14.


HLA-associated clinical progression correlates with epitope reversion rates in early human immunodeficiency virus infection.

Duda A, Lee-Turner L, Fox J, Robinson N, Dustan S, Kaye S, Fryer H, Carrington M, McClure M, McLean AR, Fidler S, Weber J, Phillips RE, Frater AJ; SPARTAC Trial Investigators.

J Virol. 2009 Feb;83(3):1228-39. doi: 10.1128/JVI.01545-08. Epub 2008 Nov 19.


Antiviral treatment for the control of pandemic influenza: some logistical constraints.

Arinaminpathy N, McLean AR.

J R Soc Interface. 2008 May 6;5(22):545-53.


Understanding the impact of Hib conjugate vaccine on transmission, immunity and disease in the United Kingdom.

McVernon J, Ramsay ME, McLean AR.

Epidemiol Infect. 2008 Jun;136(6):800-12. Epub 2007 Aug 3.

Supplemental Content

Loading ...
Support Center