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Items: 1 to 50 of 59

1.

Anti-tumor activity and mechanistic characterization of APE1/Ref-1 inhibitors in bladder cancer.

Fishel ML, Xia H, McGeown J, McIlwain DW, Elbanna M, Craft AA, Kaimakliotis HZ, Sandusky GE, Zhang C, Pili R, Kelley MR, Jerde TJ.

Mol Cancer Ther. 2019 Aug 14. pii: molcanther.1166.2018. doi: 10.1158/1535-7163.MCT-18-1166. [Epub ahead of print]

PMID:
31413178
2.

Multiomics modeling of the immunome, transcriptome, microbiome, proteome and metabolome adaptations during human pregnancy.

Ghaemi MS, DiGiulio DB, Contrepois K, Callahan B, Ngo TTM, Lee-McMullen B, Lehallier B, Robaczewska A, Mcilwain D, Rosenberg-Hasson Y, Wong RJ, Quaintance C, Culos A, Stanley N, Tanada A, Tsai A, Gaudilliere D, Ganio E, Han X, Ando K, McNeil L, Tingle M, Wise P, Maric I, Sirota M, Wyss-Coray T, Winn VD, Druzin ML, Gibbs R, Darmstadt GL, Lewis DB, Partovi Nia V, Agard B, Tibshirani R, Nolan G, Snyder MP, Relman DA, Quake SR, Shaw GM, Stevenson DK, Angst MS, Gaudilliere B, Aghaeepour N.

Bioinformatics. 2019 Jan 1;35(1):95-103. doi: 10.1093/bioinformatics/bty537.

3.

Neurological, Cognitive, and Psychological Findings Among Survivors of Ebola Virus Disease From the 1995 Ebola Outbreak in Kikwit, Democratic Republic of Congo: A Cross-sectional Study.

Kelly JD, Hoff NA, Spencer D, Musene K, Bramble MS, McIlwain D, Okitundu D, Porco TC, Rutherford GW, Glymour MM, Bjornson Z, Mukadi P, Okitolonda-Wemakoy E, Nolan GP, Muyembe-Tamfum JJ, Rimoin AW.

Clin Infect Dis. 2019 Apr 8;68(8):1388-1393. doi: 10.1093/cid/ciy677.

4.

Blood-induced bone loss in murine hemophilic arthropathy is prevented by blocking the iRhom2/ADAM17/TNF-α pathway.

Haxaire C, Hakobyan N, Pannellini T, Carballo C, McIlwain D, Mak TW, Rodeo S, Acharya S, Li D, Szymonifka J, Song X, Monette S, Srivastava A, Salmon JE, Blobel CP.

Blood. 2018 Sep 6;132(10):1064-1074. doi: 10.1182/blood-2017-12-820571. Epub 2018 May 18.

5.

APE1/Ref-1 redox-specific inhibition decreases survivin protein levels and induces cell cycle arrest in prostate cancer cells.

McIlwain DW, Fishel ML, Boos A, Kelley MR, Jerde TJ.

Oncotarget. 2017 Dec 13;9(13):10962-10977. doi: 10.18632/oncotarget.23493. eCollection 2018 Feb 16.

6.

An immune clock of human pregnancy.

Aghaeepour N, Ganio EA, Mcilwain D, Tsai AS, Tingle M, Van Gassen S, Gaudilliere DK, Baca Q, McNeil L, Okada R, Ghaemi MS, Furman D, Wong RJ, Winn VD, Druzin ML, El-Sayed YY, Quaintance C, Gibbs R, Darmstadt GL, Shaw GM, Stevenson DK, Tibshirani R, Nolan GP, Lewis DB, Angst MS, Gaudilliere B.

Sci Immunol. 2017 Sep 1;2(15). pii: eaan2946. doi: 10.1126/sciimmunol.aan2946.

7.

The xenoestrogens biphenol-A and nonylphenol differentially regulate metalloprotease-mediated shedding of EGFR ligands.

Urriola-Muñoz P, Li X, Maretzky T, McIlwain DR, Mak TW, Reyes JG, Blobel CP, Moreno RD.

J Cell Physiol. 2018 Mar;233(3):2247-2256. doi: 10.1002/jcp.26097. Epub 2017 Aug 25.

8.

Hearing Loss and Tinnitus in Military Personnel with Deployment-Related Mild Traumatic Brain Injury.

Karch SJ, Capó-Aponte JE, McIlwain DS, Lo M, Krishnamurti S, Staton RN, Jorgensen-Wagers K.

US Army Med Dep J. 2016 Oct-Dec;(3-16):52-63.

PMID:
27613210
9.

RAIDD Mediates TLR3 and IRF7 Driven Type I Interferon Production.

Maney SK, Xu HC, Huang J, Pandyra AA, Ehlting C, Aguilar-Valenzuela R, Pozdeev VI, McIlwain DR, Zimmermann A, Bode JG, Hengel H, Kirschning CJ, Kim IR, Hiscott J, Brenner D, Häussinger D, Ohashi PS, Mak TW, Lang KS, Lang PA.

Cell Physiol Biochem. 2016;39(4):1271-80. doi: 10.1159/000447832. Epub 2016 Sep 8.

10.

iRhom2 regulates CSF1R cell surface expression and non-steady state myelopoiesis in mice.

Qing X, Rogers L, Mortha A, Lavin Y, Redecha P, Issuree PD, Maretzky T, Merad M, McIlwain D, Mak TW, Overall CM, Blobel CP, Salmon JE.

Eur J Immunol. 2016 Dec;46(12):2737-2748. doi: 10.1002/eji.201646482. Epub 2016 Sep 28.

11.

A qualitative comparison of needles and insulin pump use in children with type 1 diabetes.

Ferrari M, McIlwain DJ, Ambler G.

J Health Psychol. 2018 Sep;23(10):1332-1342. doi: 10.1177/1359105316653999. Epub 2016 Jun 22.

PMID:
27338629
12.

Coordinated induction of cell survival signaling in the inflamed microenvironment of the prostate.

McIlwain DW, Zoetemelk M, Myers JD, Edwards MT, Snider BM, Jerde TJ.

Prostate. 2016 Jun;76(8):722-34. doi: 10.1002/pros.23161. Epub 2016 Feb 24.

PMID:
27088546
13.

Deletions in the cytoplasmic domain of iRhom1 and iRhom2 promote shedding of the TNF receptor by the protease ADAM17.

Maney SK, McIlwain DR, Polz R, Pandyra AA, Sundaram B, Wolff D, Ohishi K, Maretzky T, Brooke MA, Evers A, Vasudevan AA, Aghaeepour N, Scheller J, Münk C, Häussinger D, Mak TW, Nolan GP, Kelsell DP, Blobel CP, Lang KS, Lang PA.

Sci Signal. 2015 Nov 3;8(401):ra109. doi: 10.1126/scisignal.aac5356.

PMID:
26535007
14.

iRhoms 1 and 2 are essential upstream regulators of ADAM17-dependent EGFR signaling.

Li X, Maretzky T, Weskamp G, Monette S, Qing X, Issuree PD, Crawford HC, McIlwain DR, Mak TW, Salmon JE, Blobel CP.

Proc Natl Acad Sci U S A. 2015 May 12;112(19):6080-5. doi: 10.1073/pnas.1505649112. Epub 2015 Apr 27.

15.

Caspase functions in cell death and disease.

McIlwain DR, Berger T, Mak TW.

Cold Spring Harb Perspect Biol. 2015 Apr 1;7(4). pii: a026716. doi: 10.1101/cshperspect.a026716. No abstract available.

16.

Deficiency of the B cell-activating factor receptor results in limited CD169+ macrophage function during viral infection.

Xu HC, Huang J, Khairnar V, Duhan V, Pandyra AA, Grusdat M, Shinde P, McIlwain DR, Maney SK, Gommerman J, Löhning M, Ohashi PS, Mak TW, Pieper K, Sic H, Speletas M, Eibel H, Ware CF, Tumanov AV, Kruglov AA, Nedospasov SA, Häussinger D, Recher M, Lang KS, Lang PA.

J Virol. 2015 May;89(9):4748-59. doi: 10.1128/JVI.02976-14. Epub 2015 Feb 11.

17.

The performative pleasure of imprecision: a diachronic study of entrainment in music performance.

Geeves A, McIlwain DJ, Sutton J.

Front Hum Neurosci. 2014 Oct 29;8:863. doi: 10.3389/fnhum.2014.00863. eCollection 2014.

18.

T-cell STAT3 is required for the maintenance of humoral immunity to LCMV.

McIlwain DR, Grusdat M, Pozdeev VI, Xu HC, Shinde P, Reardon C, Hao Z, Beyer M, Bergthaler A, Häussinger D, Nolan GP, Lang KS, Lang PA.

Eur J Immunol. 2015 Feb;45(2):418-27. doi: 10.1002/eji.201445060. Epub 2014 Dec 15.

19.

IRF4 and BATF are critical for CD8⁺ T-cell function following infection with LCMV.

Grusdat M, McIlwain DR, Xu HC, Pozdeev VI, Knievel J, Crome SQ, Robert-Tissot C, Dress RJ, Pandyra AA, Speiser DE, Lang E, Maney SK, Elford AR, Hamilton SR, Scheu S, Pfeffer K, Bode J, Mittrücker HW, Lohoff M, Huber M, Häussinger D, Ohashi PS, Mak TW, Lang KS, Lang PA.

Cell Death Differ. 2014 Jul;21(7):1050-60. doi: 10.1038/cdd.2014.19. Epub 2014 Feb 14.

20.

Parity and breastfeeding among African-American women: differential effects on breast cancer risk by estrogen receptor status in the Women's Circle of Health Study.

Ambrosone CB, Zirpoli G, Ruszczyk M, Shankar J, Hong CC, McIlwain D, Roberts M, Yao S, McCann SE, Ciupak G, Hwang H, Khoury T, Jandorf L, Bovbjerg DH, Pawlish K, Bandera EV.

Cancer Causes Control. 2014 Feb;25(2):259-65. doi: 10.1007/s10552-013-0323-9. Epub 2013 Nov 19.

21.

iRhom2 controls the substrate selectivity of stimulated ADAM17-dependent ectodomain shedding.

Maretzky T, McIlwain DR, Issuree PD, Li X, Malapeira J, Amin S, Lang PA, Mak TW, Blobel CP.

Proc Natl Acad Sci U S A. 2013 Jul 9;110(28):11433-8. doi: 10.1073/pnas.1302553110. Epub 2013 Jun 25.

22.

Caspase functions in cell death and disease.

McIlwain DR, Berger T, Mak TW.

Cold Spring Harb Perspect Biol. 2013 Apr 1;5(4):a008656. doi: 10.1101/cshperspect.a008656. Review. Erratum in: Cold Spring Harb Perspect Biol. 2015 Apr;7(4). pii: a026716. doi: 10.1101/cshperspect.a026716.

23.

Involvement of Toso in activation of monocytes, macrophages, and granulocytes.

Lang KS, Lang PA, Meryk A, Pandyra AA, Boucher LM, Pozdeev VI, Tusche MW, Göthert JR, Haight J, Wakeham A, You-Ten AJ, McIlwain DR, Merches K, Khairnar V, Recher M, Nolan GP, Hitoshi Y, Funkner P, Navarini AA, Verschoor A, Shaabani N, Honke N, Penn LZ, Ohashi PS, Häussinger D, Lee KH, Mak TW.

Proc Natl Acad Sci U S A. 2013 Feb 12;110(7):2593-8. doi: 10.1073/pnas.1222264110. Epub 2013 Jan 28.

24.

iRHOM2 is a critical pathogenic mediator of inflammatory arthritis.

Issuree PD, Maretzky T, McIlwain DR, Monette S, Qing X, Lang PA, Swendeman SL, Park-Min KH, Binder N, Kalliolias GD, Yarilina A, Horiuchi K, Ivashkiv LB, Mak TW, Salmon JE, Blobel CP.

J Clin Invest. 2013 Feb;123(2):928-32. doi: 10.1172/JCI66168. Epub 2013 Jan 25.

25.

Reactive oxygen species delay control of lymphocytic choriomeningitis virus.

Lang PA, Xu HC, Grusdat M, McIlwain DR, Pandyra AA, Harris IS, Shaabani N, Honke N, Maney SK, Lang E, Pozdeev VI, Recher M, Odermatt B, Brenner D, Häussinger D, Ohashi PS, Hengartner H, Zinkernagel RM, Mak TW, Lang KS.

Cell Death Differ. 2013 Apr;20(4):649-58. doi: 10.1038/cdd.2012.167. Epub 2013 Jan 18.

26.

iRhom2 regulation of TACE controls TNF-mediated protection against Listeria and responses to LPS.

McIlwain DR, Lang PA, Maretzky T, Hamada K, Ohishi K, Maney SK, Berger T, Murthy A, Duncan G, Xu HC, Lang KS, Häussinger D, Wakeham A, Itie-Youten A, Khokha R, Ohashi PS, Blobel CP, Mak TW.

Science. 2012 Jan 13;335(6065):229-32. doi: 10.1126/science.1214448.

27.

Marine Corps Breacher Training Study: auditory and vestibular findings.

St Onge P, McIlwain DS, Hill ME, Walilko TJ, Bardolf LB.

US Army Med Dep J. 2011 Jul-Sep:97-107.

PMID:
21805461
28.

Smg1 is required for embryogenesis and regulates diverse genes via alternative splicing coupled to nonsense-mediated mRNA decay.

McIlwain DR, Pan Q, Reilly PT, Elia AJ, McCracken S, Wakeham AC, Itie-Youten A, Blencowe BJ, Mak TW.

Proc Natl Acad Sci U S A. 2010 Jul 6;107(27):12186-91. doi: 10.1073/pnas.1007336107. Epub 2010 Jun 21.

29.

Dynamic leadership: essential for the 21st century.

McIlwain DS.

US Army Med Dep J. 2009 Oct-Dec:27-31. No abstract available.

PMID:
20073360
30.

Heritage of army audiology and the road ahead: the Army Hearing Program.

McIlwain DS, Gates K, Ciliax D.

Am J Public Health. 2008 Dec;98(12):2167-72. doi: 10.2105/AJPH.2007.128504. Epub 2008 Oct 15.

31.

Evolution of the Army Hearing Program.

McIlwain DS, Cave K, Gates K, Ciliax D.

US Army Med Dep J. 2008 Apr-Jun:62-6. No abstract available.

PMID:
20084731
33.

Differential inhibition of postnatal brain, spinal cord and body growth by a growth hormone antagonist.

McIlwain DL, Hoke VB, Kopchick JJ, Fuller CR, Lund PK.

BMC Neurosci. 2004 Feb 23;5:6.

34.

Neuron addition and enlargement in juvenile and adult animals.

Farel PB, McIlwain DL.

Brain Res Bull. 2000 Nov 15;53(5):537-46. Review.

PMID:
11165789
36.

Growth hormone, insulin-like growth factor I, and motoneuron size.

Chen L, Lund PK, Burgess SB, Rudisch BE, McIlwain DL.

J Neurobiol. 1997 Feb;32(2):202-12.

PMID:
9032662
37.

Synchronous, intersegmental responses in motoneurons to lumbar ventral root injury.

Burgess SB, McIlwain DL.

Neuroreport. 1994 Dec 20;5(18):2641-4.

PMID:
7696622
38.

Transcription and motoneuron size.

Sato S, Burgess SB, McIlwain DL.

J Neurochem. 1994 Nov;63(5):1609-15.

PMID:
7523596
39.

Radiolabeling motoneuron proteins in the isolated frog spinal cord preparation.

McIlwain DL, Hoke VB.

J Neurosci Methods. 1994 Jun;52(2):197-202.

PMID:
7967722
40.

Nuclear and cell body size in spinal motor neurons.

McIlwain DL.

Adv Neurol. 1991;56:67-74. No abstract available.

PMID:
1853783
41.

Isolation of motoneuron cell bodies from spinal cord stored at -70 degrees C in ethylene glycol.

Sinicropi DV, Hoke VB, McIlwain DL.

Anal Biochem. 1989 Aug 1;180(2):286-90.

PMID:
2817357
42.

Allocation of newly synthesized proteins in spinal motoneurons.

McIlwain DL, Hoke VB.

Rev Neurol (Paris). 1988;144(11):697-700.

PMID:
3231958
43.
44.
45.

Cholinergic enzyme activity in neurons of the developing anuran spinal cord.

Farel PB, McIlwain DL.

Brain Res. 1983 Jun;284(2-3):275-82.

PMID:
6603253
46.
47.

Acetylcholinesterase distribution in axotomized frog motoneurons.

Sinicropi DV, Michels K, McIlwain DL.

J Neurochem. 1982 Apr;38(4):1099-105.

PMID:
6977618
48.

Television-based densitometric analysis of proteins separated by two-dimensional gel electrophoresis.

Aycock BF, Weil DE, Sinicropi DV, McIlwain DL.

Comput Biomed Res. 1981 Aug;14(4):314-26. No abstract available.

PMID:
7261571
49.
50.

Initiation and time course of mitosis of non-neuronal cells after spinal motoneuron axotomy.

McIlwain DL, Farel PB.

Brain Res. 1979 Dec 14;178(2-3):519-28.

PMID:
315812

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