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Items: 44


The evolution of radiographic edema in ARDS and its association with clinical outcomes: A prospective cohort study in adult patients.

Kotok D, Yang L, Evankovich JW, Bain W, Dunlap DG, Shah F, Zhang Y, Manatakis DV, Benos PV, Barbash IJ, Rapport SF, Lee JS, Morris A, McVerry BJ, Kitsios GD.

J Crit Care. 2020 Jan 13;56:222-228. doi: 10.1016/j.jcrc.2020.01.012. [Epub ahead of print]


Clinical Characterization of E-cigarette, or Vaping, Product Use Associated Lung Injury in 36 Patients in Pittsburgh, PA.

Zou RH, Tiberio PJ, Triantafyllou GA, Lamberty PE, Lynch MJ, Kreit JW, McVerry BJ, Gladwin MT, Morris A, Chiarchiaro J, Fitzpatrick ME, Rose JJ.

Am J Respir Crit Care Med. 2020 Feb 5. doi: 10.1164/rccm.202001-0079LE. [Epub ahead of print] No abstract available.


The RNFT2/IL-3Rα axis regulates IL-3 signaling and innate immunity.

Tong Y, Lear TB, Evankovich J, Chen Y, Londino JD, Myerburg MM, Zhang Y, Popescu ID, McDyer JF, McVerry BJ, Lockwood KC, Jurczak MJ, Liu Y, Chen BB.

JCI Insight. 2020 Feb 13;5(3). pii: 133652. doi: 10.1172/jci.insight.133652.


Metagenomic identification of severe pneumonia pathogens in mechanically-ventilated patients: a feasibility and clinical validity study.

Yang L, Haidar G, Zia H, Nettles R, Qin S, Wang X, Shah F, Rapport SF, Charalampous T, Methé B, Fitch A, Morris A, McVerry BJ, O'Grady J, Kitsios GD.

Respir Res. 2019 Nov 27;20(1):265. doi: 10.1186/s12931-019-1218-4.


Host-Response Subphenotypes Offer Prognostic Enrichment in Patients With or at Risk for Acute Respiratory Distress Syndrome.

Kitsios GD, Yang L, Manatakis DV, Nouraie M, Evankovich J, Bain W, Dunlap DG, Shah F, Barbash IJ, Rapport SF, Zhang Y, DeSensi RS, Weathington NM, Chen BB, Ray P, Mallampalli RK, Benos PV, Lee JS, Morris A, McVerry BJ.

Crit Care Med. 2019 Dec;47(12):1724-1734. doi: 10.1097/CCM.0000000000004018.


KIAA0317 regulates pulmonary inflammation through SOCS2 degradation.

Lear TB, McKelvey AC, Evankovich JW, Rajbhandari S, Coon TA, Dunn SR, Londino JD, McVerry BJ, Zhang Y, Valenzi E, Burton CL, Gordon R, Gingras S, Lockwood KC, Jurczak MJ, Lafyatis R, Shlomchik MJ, Liu Y, Chen BB.

JCI Insight. 2019 Oct 3;4(19). pii: 129110. doi: 10.1172/jci.insight.129110.


Rectal Swabs from Critically Ill Patients Provide Discordant Representations of the Gut Microbiome Compared to Stool Samples.

Fair K, Dunlap DG, Fitch A, Bogdanovich T, Methé B, Morris A, McVerry BJ, Kitsios GD.

mSphere. 2019 Jul 24;4(4). pii: e00358-19. doi: 10.1128/mSphere.00358-19.


Therapeutic Effects of Endogenous Incretin Hormones and Exogenous Incretin-Based Medications in Sepsis.

Shah FA, Mahmud H, Gallego-Martin T, Jurczak MJ, O'Donnell CP, McVerry BJ.

J Clin Endocrinol Metab. 2019 Nov 1;104(11):5274-5284. doi: 10.1210/jc.2019-00296.


Rationale for and Design of the Study of Early Enteral Dextrose in Sepsis: A Pilot Placebo-Controlled Randomized Clinical Trial.

Shah FA, Kitsios GD, Zhang Y, Morris A, Yende S, Huang DT, O'Donnell CP, McVerry BJ.

JPEN J Parenter Enteral Nutr. 2019 May 30. doi: 10.1002/jpen.1608. [Epub ahead of print]


Closing the Loop: Engaging Leaders and Front-Line Physicians to Promote Physician Wellness.

Barbash IJ, Pilewski JM, McVerry BJ.

Ann Am Thorac Soc. 2019 Aug;16(8):970-973. doi: 10.1513/AnnalsATS.201812-866PS. No abstract available.


Improved Detection of Culprit Pathogens by Bacterial DNA Sequencing Affects Antibiotic Management Decisions in Severe Pneumonia.

Dunlap DG, Marshall CW, Fitch A, Rapport SF, Cooper VS, McVerry BJ, Morris A, Kitsios GD.

Am J Case Rep. 2018 Nov 26;19:1405-1409. doi: 10.12659/AJCR.912055.


Treatment with allogeneic mesenchymal stromal cells for moderate to severe acute respiratory distress syndrome (START study): a randomised phase 2a safety trial.

Matthay MA, Calfee CS, Zhuo H, Thompson BT, Wilson JG, Levitt JE, Rogers AJ, Gotts JE, Wiener-Kronish JP, Bajwa EK, Donahoe MP, McVerry BJ, Ortiz LA, Exline M, Christman JW, Abbott J, Delucchi KL, Caballero L, McMillan M, McKenna DH, Liu KD.

Lancet Respir Med. 2019 Feb;7(2):154-162. doi: 10.1016/S2213-2600(18)30418-1. Epub 2018 Nov 16.


Sleep phenotype in the Townes mouse model of sickle cell disease.

O'Donnell BJ, Guo L, Ghosh S, Shah FA, Strollo PJ Jr, McVerry BJ, Gladwin MT, Ofori-Acquah SF, Kato GJ, O'Donnell CP.

Sleep Breath. 2019 Mar;23(1):333-339. doi: 10.1007/s11325-018-1711-x. Epub 2018 Aug 29.


Respiratory Microbiome Profiling for Etiologic Diagnosis of Pneumonia in Mechanically Ventilated Patients.

Kitsios GD, Fitch A, Manatakis DV, Rapport SF, Li K, Qin S, Huwe J, Zhang Y, Doi Y, Evankovich J, Bain W, Lee JS, Methé B, Benos PV, Morris A, McVerry BJ.

Front Microbiol. 2018 Jul 10;9:1413. doi: 10.3389/fmicb.2018.01413. eCollection 2018.


The Lung Microbiome in Hematopoietic Stem Cell Transplant. Where the Money Lies.

McVerry BJ, Morris A.

Am J Respir Crit Care Med. 2018 Nov 15;198(10):1249-1251. doi: 10.1164/rccm.201806-1088ED. No abstract available.


Host-Microbiome Interactions in the Subglottic Space. Bacteria Ante Portas!

Kitsios GD, McVerry BJ.

Am J Respir Crit Care Med. 2018 Aug 1;198(3):294-297. doi: 10.1164/rccm.201802-0276ED. No abstract available.


Nocturnal Hypoxia Improves Glucose Disposal, Decreases Mitochondrial Efficiency, and Increases Reactive Oxygen Species in the Muscle and Liver of C57BL/6J Mice Independent of Weight Change.

Ioja S, Singamsetty S, Corey C, Guo L, Shah F, Jurczak MJ, McVerry BJ, Shiva S, O'Donnell CP.

Oxid Med Cell Longev. 2018 Feb 4;2018:9649608. doi: 10.1155/2018/9649608. eCollection 2018.


Stimulation of the endogenous incretin glucose-dependent insulinotropic peptide by enteral dextrose improves glucose homeostasis and inflammation in murine endotoxemia.

Shah FA, Singamsetty S, Guo L, Chuan BW, McDonald S, Cooper BA, O'Donnell BJ, Stefanovski D, Wice B, Zhang Y, O'Donnell CP, McVerry BJ.

Transl Res. 2018 Mar;193:1-12. doi: 10.1016/j.trsl.2017.11.001. Epub 2017 Nov 21.


Ketamine Infusion for Adjunct Sedation in Mechanically Ventilated Adults.

Groetzinger LM, Rivosecchi RM, Bain W, Bahr M, Chin K, McVerry BJ, Barbash I.

Pharmacotherapy. 2018 Feb;38(2):181-188. doi: 10.1002/phar.2065. Epub 2018 Jan 10.


Microbiome in lung explants of idiopathic pulmonary fibrosis: a case-control study in patients with end-stage fibrosis.

Kitsios GD, Rojas M, Kass DJ, Fitch A, Sembrat JC, Qin S, Veraldi KL, Gibson KF, Lindell K, Pilewski JM, Methe B, Li K, McDyer J, McVerry BJ, Morris A.

Thorax. 2018 May;73(5):481-484. doi: 10.1136/thoraxjnl-2017-210537. Epub 2017 Aug 11.


Dysbiosis in the intensive care unit: Microbiome science coming to the bedside.

Kitsios GD, Morowitz MJ, Dickson RP, Huffnagle GB, McVerry BJ, Morris A.

J Crit Care. 2017 Apr;38:84-91. doi: 10.1016/j.jcrc.2016.09.029. Epub 2016 Oct 11. Review.


RING finger E3 ligase PPP1R11 regulates TLR2 signaling and innate immunity.

McKelvey AC, Lear TB, Dunn SR, Evankovich J, Londino JD, Bednash JS, Zhang Y, McVerry BJ, Liu Y, Chen BB.

Elife. 2016 Nov 2;5. pii: e18496. doi: 10.7554/eLife.18496.


Full Spectrum of LPS Activation in Alveolar Macrophages of Healthy Volunteers by Whole Transcriptomic Profiling.

Pinilla-Vera M, Xiong Z, Zhao Y, Zhao J, Donahoe MP, Barge S, Horne WT, Kolls JK, McVerry BJ, Birukova A, Tighe RM, Foster WM, Hollingsworth J, Ray A, Mallampalli R, Ray P, Lee JS.

PLoS One. 2016 Jul 19;11(7):e0159329. doi: 10.1371/journal.pone.0159329. eCollection 2016.


Antibiotic de-escalation: observational causal inference and culture dependence.

Kitsios GD, Morris A, McVerry BJ.

Intensive Care Med. 2016 Oct;42(10):1647-1648. doi: 10.1007/s00134-016-4443-z. Epub 2016 Jul 18. No abstract available.


Early initiation of low-level parenteral dextrose induces an accelerated diabetic phenotype in septic C57BL/6J mice.

Singamsetty S, Shah FA, Guo L, Watanabe Y, McDonald S, Sharma R, Zhang Y, Alonso LC, O'Donnell CP, McVerry BJ.

Appl Physiol Nutr Metab. 2016 Jan;41(1):12-9. doi: 10.1139/apnm-2015-0213. Epub 2015 Sep 9.


The proinflammatory role of HECTD2 in innate immunity and experimental lung injury.

Coon TA, McKelvey AC, Lear T, Rajbhandari S, Dunn SR, Connelly W, Zhao JY, Han S, Liu Y, Weathington NM, McVerry BJ, Zhang Y, Chen BB.

Sci Transl Med. 2015 Jul 8;7(295):295ra109. doi: 10.1126/scitranslmed.aab3881.


Inorganic nitrite improves components of the metabolic syndrome independent of weight change in a murine model of obesity and insulin resistance.

Singamsetty S, Watanabe Y, Guo L, Corey C, Wang Y, Tejero J, McVerry BJ, Gladwin MT, Shiva S, O'Donnell CP.

J Physiol. 2015 Jul 15;593(14):3135-45. doi: 10.1113/JP270386. Epub 2015 Jun 25.


Nox2-dependent glutathionylation of endothelial NOS leads to uncoupled superoxide production and endothelial barrier dysfunction in acute lung injury.

Wu F, Szczepaniak WS, Shiva S, Liu H, Wang Y, Wang L, Wang Y, Kelley EE, Chen AF, Gladwin MT, McVerry BJ.

Am J Physiol Lung Cell Mol Physiol. 2014 Dec 15;307(12):L987-97. doi: 10.1152/ajplung.00063.2014. Epub 2014 Oct 17.


Aging mesenchymal stem cells fail to protect because of impaired migration and antiinflammatory response.

Bustos ML, Huleihel L, Kapetanaki MG, Lino-Cardenas CL, Mroz L, Ellis BM, McVerry BJ, Richards TJ, Kaminski N, Cerdenes N, Mora AL, Rojas M.

Am J Respir Crit Care Med. 2014 Apr 1;189(7):787-98. doi: 10.1164/rccm.201306-1043OC.


Activation of human mesenchymal stem cells impacts their therapeutic abilities in lung injury by increasing interleukin (IL)-10 and IL-1RN levels.

Bustos ML, Huleihel L, Meyer EM, Donnenberg AD, Donnenberg VS, Sciurba JD, Mroz L, McVerry BJ, Ellis BM, Kaminski N, Rojas M.

Stem Cells Transl Med. 2013 Nov;2(11):884-95. doi: 10.5966/sctm.2013-0033. Epub 2013 Oct 2.


Exogenous glucose administration impairs glucose tolerance and pancreatic insulin secretion during acute sepsis in non-diabetic mice.

Watanabe Y, Singamsetty S, Zou B, Guo L, Stefanovski D, Alonso LC, Garcia-Ocana A, O'Donnell CP, McVerry BJ.

PLoS One. 2013 Jun 24;8(6):e67716. doi: 10.1371/journal.pone.0067716. Print 2013.


A combinatorial F box protein directed pathway controls TRAF adaptor stability to regulate inflammation.

Chen BB, Coon TA, Glasser JR, McVerry BJ, Zhao J, Zhao Y, Zou C, Ellis B, Sciurba FC, Zhang Y, Mallampalli RK.

Nat Immunol. 2013 May;14(5):470-9. doi: 10.1038/ni.2565. Epub 2013 Mar 31.


Doppler-defined pulmonary hypertension in medical intensive care unit patients: Retrospective investigation of risk factors and impact on mortality.

Stamm JA, McVerry BJ, Mathier MA, Donahoe MP, Saul MI, Gladwin MT.

Pulm Circ. 2011 Jan-Mar;1(1):95-102. doi: 10.4103/2045-8932.78104.


Dynamic regulation of cardiolipin by the lipid pump Atp8b1 determines the severity of lung injury in experimental pneumonia.

Ray NB, Durairaj L, Chen BB, McVerry BJ, Ryan AJ, Donahoe M, Waltenbaugh AK, O'Donnell CP, Henderson FC, Etscheidt CA, McCoy DM, Agassandian M, Hayes-Rowan EC, Coon TA, Butler PL, Gakhar L, Mathur SN, Sieren JC, Tyurina YY, Kagan VE, McLennan G, Mallampalli RK.

Nat Med. 2010 Oct;16(10):1120-1127. doi: 10.1038/nm.2213. Epub 2010 Sep 19.


S1P2 receptor-dependent Rho-kinase activation mediates vasoconstriction in the murine pulmonary circulation induced by sphingosine 1-phosphate.

Szczepaniak WS, Pitt BR, McVerry BJ.

Am J Physiol Lung Cell Mol Physiol. 2010 Jul;299(1):L137-45. doi: 10.1152/ajplung.00233.2009. Epub 2010 Apr 30.


Hyperinsulinemia predicts survival in a hyperglycemic mouse model of critical illness.

Woodske ME, Yokoe T, Zou B, Romano LC, Rosa TC, Garcia-Ocana A, Alonso LC, O'Donnell CP, McVerry BJ.

Crit Care Med. 2009 Sep;37(9):2596-603. doi: 10.1097/CCM.0b013e3181a9338a.


Sphingosine 1-phosphate rescues canine LPS-induced acute lung injury and alters systemic inflammatory cytokine production in vivo.

Szczepaniak WS, Zhang Y, Hagerty S, Crow MT, Kesari P, Garcia JG, Choi AM, Simon BA, McVerry BJ.

Transl Res. 2008 Nov;152(5):213-24. doi: 10.1016/j.trsl.2008.09.002. Epub 2008 Oct 11.


Pre-B-cell colony-enhancing factor as a potential novel biomarker in acute lung injury.

Ye SQ, Simon BA, Maloney JP, Zambelli-Weiner A, Gao L, Grant A, Easley RB, McVerry BJ, Tuder RM, Standiford T, Brower RG, Barnes KC, Garcia JG.

Am J Respir Crit Care Med. 2005 Feb 15;171(4):361-70. Epub 2004 Dec 3.


Sphingosine 1-phosphate reduces vascular leak in murine and canine models of acute lung injury.

McVerry BJ, Peng X, Hassoun PM, Sammani S, Simon BA, Garcia JG.

Am J Respir Crit Care Med. 2004 Nov 1;170(9):987-93. Epub 2004 Jul 28.


Endothelial cell barrier regulation by sphingosine 1-phosphate.

McVerry BJ, Garcia JG.

J Cell Biochem. 2004 Aug 15;92(6):1075-85. Review.


Protective effects of sphingosine 1-phosphate in murine endotoxin-induced inflammatory lung injury.

Peng X, Hassoun PM, Sammani S, McVerry BJ, Burne MJ, Rabb H, Pearse D, Tuder RM, Garcia JG.

Am J Respir Crit Care Med. 2004 Jun 1;169(11):1245-51. Epub 2004 Mar 12.


Cardiac arrest research methodology.

McVerry BJ, Sayre MR.

Prehosp Emerg Care. 2002 Apr-Jun;6(2 Suppl):S57-62. Review. No abstract available.


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