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Items: 22

1.

A potential treatment for pandemic influenza using siRNAs targeting conserved regions of influenza A.

McSwiggen JA, Seth S.

Expert Opin Biol Ther. 2008 Mar;8(3):299-313. doi: 10.1517/14712598.8.3.299 . Review.

PMID:
18294101
2.

Activity of stabilized short interfering RNA in a mouse model of hepatitis B virus replication.

Morrissey DV, Blanchard K, Shaw L, Jensen K, Lockridge JA, Dickinson B, McSwiggen JA, Vargeese C, Bowman K, Shaffer CS, Polisky BA, Zinnen S.

Hepatology. 2005 Jun;41(6):1349-56.

PMID:
15880588
3.

High-throughput ribozyme-based assays for detection of viral nucleic acids.

Kossen K, Vaish NK, Jadhav VR, Pasko C, Wang H, Jenison R, McSwiggen JA, Polisky B, Seiwert SD.

Chem Biol. 2004 Jun;11(6):807-15.

4.

Development and validation of a sensitive, specific, and rapid hybridization-ELISA assay for determination of concentrations of a ribozyme in biological matrices.

Brown-Augsburger P, Yue XM, Lockridge JA, McSwiggen JA, Kamboj D, Hillgren KM.

J Pharm Biomed Anal. 2004 Jan 27;34(1):129-39.

PMID:
14738927
5.

Zeptomole detection of a viral nucleic acid using a target-activated ribozyme.

Vaish NK, Jadhav VR, Kossen K, Pasko C, Andrews LE, McSwiggen JA, Polisky B, Seiwert SD.

RNA. 2003 Sep;9(9):1058-72.

6.

Characterization of nuclease-resistant ribozymes directed against hepatitis B virus RNA.

Morrissey DV, Lee PA, Johnson DA, Overly SL, McSwiggen JA, Beigelman L, Mokler VR, Maloney L, Vargeese C, Bowman K, O'Brien JT, Shaffer CS, Conrad A, Schmid P, Morrey JD, Macejak DG, Pavco PA, Blatt LM.

J Viral Hepat. 2002 Nov;9(6):411-8.

PMID:
12431202
7.
8.

Quantitation of ribozyme target abundance by QCPCR.

Beaudry AA, McSwiggen JA.

Methods Mol Biol. 1997;74:325-39. No abstract available.

PMID:
9204447
9.

Optimizing the cell efficacy of synthetic ribozymes. Site selection and chemical modifications of ribozymes targeting the proto-oncogene c-myb.

Jarvis TC, Wincott FE, Alby LJ, McSwiggen JA, Beigelman L, Gustofson J, DiRenzo A, Levy K, Arthur M, Matulic-Adamic J, Karpeisky A, Gonzalez C, Woolf TM, Usman N, Stinchcomb DT.

J Biol Chem. 1996 Nov 15;271(46):29107-12.

10.

Chemically modified hammerhead ribozymes with improved catalytic rates.

Burgin AB Jr, Gonzalez C, Matulic-Adamic J, Karpeisky AM, Usman N, McSwiggen JA, Beigelman L.

Biochemistry. 1996 Nov 12;35(45):14090-7.

PMID:
8916894
11.

Hammerhead ribozyme engineering.

Usman N, Beigelman L, McSwiggen JA.

Curr Opin Struct Biol. 1996 Aug;6(4):527-33. Review.

PMID:
8794164
12.

Inhibition of vascular smooth muscle cell proliferation by ribozymes that cleave c-myb mRNA.

Jarvis TC, Alby LJ, Beaudry AA, Wincott FE, Beigelman L, McSwiggen JA, Usman N, Stinchcomb DT.

RNA. 1996 May;2(5):419-28.

13.

Chemical modification of hammerhead ribozymes. Catalytic activity and nuclease resistance.

Beigelman L, McSwiggen JA, Draper KG, Gonzalez C, Jensen K, Karpeisky AM, Modak AS, Matulic-Adamic J, DiRenzo AB, Haeberli P, et al.

J Biol Chem. 1995 Oct 27;270(43):25702-8.

14.

HIV-1 TAR RNA has an intrinsic ability to activate interferon-inducible enzymes.

Maitra RK, McMillan NA, Desai S, McSwiggen J, Hovanessian AG, Sen G, Williams BR, Silverman RH.

Virology. 1994 Nov 1;204(2):823-7.

PMID:
7524241
15.
16.

Functional characterization of ribozymes expressed using U1 and T7 vectors for the intracellular cleavage of ANF mRNA.

De Young MB, Kincade-Denker J, Boehm CA, Riek RP, Mamone JA, McSwiggen JA, Graham RM.

Biochemistry. 1994 Oct 11;33(40):12127-38.

PMID:
7918434
17.

Direct measurement of oligonucleotide substrate binding to wild-type and mutant ribozymes from Tetrahymena.

Pyle AM, McSwiggen JA, Cech TR.

Proc Natl Acad Sci U S A. 1990 Nov;87(21):8187-91.

18.
19.

Interactions of Escherichia coli transcription termination factor rho with RNA. II. Electron microscopy and nuclease protection experiments.

Bear DG, Hicks PS, Escudero KW, Andrews CL, McSwiggen JA, von Hippel PH.

J Mol Biol. 1988 Feb 20;199(4):623-35.

PMID:
2451029
20.
21.

Cooperative and noncooperative binding of protein ligands to nucleic acid lattices: experimental approaches to the determination of thermodynamic parameters.

Kowalczykowski SC, Paul LS, Lonberg N, Newport JW, McSwiggen JA, von Hippel PH.

Biochemistry. 1986 Mar 25;25(6):1226-40. Erratum in: Biochemistry 1986 Dec 30;25(26):8473.

PMID:
3486003
22.

Protein-nucleic acid interactions in transcription: a molecular analysis.

von Hippel PH, Bear DG, Morgan WD, McSwiggen JA.

Annu Rev Biochem. 1984;53:389-446. Review. No abstract available.

PMID:
6206781

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