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The relationship between cardiopulmonary exercise test variables, the systemic inflammatory response, and complications following surgery for colorectal cancer.

McSorley ST, Roxburgh CSD, Horgan PG, McMillan DC.

Perioper Med (Lond). 2018 Jun 15;7:11. doi: 10.1186/s13741-018-0093-8. eCollection 2018.


Comment on the Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA) project.

McSorley ST, Talwar D, McMillan DC.

Am J Clin Nutr. 2018 Jul 1;108(1):204-205. doi: 10.1093/ajcn/nqx071. No abstract available.


Multi-color flow cytometry for evaluating age-related changes in memory lymphocyte subsets in dogs.

Withers SS, Moore PF, Chang H, Choi JW, McSorley SJ, Kent MS, Monjazeb AM, Canter RJ, Murphy WJ, Sparger EE, Rebhun RB.

Dev Comp Immunol. 2018 May 31;87:64-74. doi: 10.1016/j.dci.2018.05.022. [Epub ahead of print]


The prognostic value of systemic inflammation in patients undergoing surgery for colon cancer: comparison of composite ratios and cumulative scores.

Dolan RD, McSorley ST, Park JH, Watt DG, Roxburgh CS, Horgan PG, McMillan DC.

Br J Cancer. 2018 Jul;119(1):40-51. doi: 10.1038/s41416-018-0095-9. Epub 2018 May 23.


Determinants of lymph node count and positivity in patients undergoing surgery for colon cancer.

Dolan RD, McSorley ST, Horgan PG, McMillan DC.

Medicine (Baltimore). 2018 Mar;97(13):e0185. doi: 10.1097/MD.0000000000010185.


The relationship between right-sided tumour location, tumour microenvironment, systemic inflammation, adjuvant therapy and survival in patients undergoing surgery for colon and rectal cancer.

Patel M, McSorley ST, Park JH, Roxburgh CSD, Edwards J, Horgan PG, McMillan DC.

Br J Cancer. 2018 Mar 6;118(5):705-712. doi: 10.1038/bjc.2017.441. Epub 2018 Jan 16.


The relationship between body mass index and short term postoperative outcomes in patients undergoing potentially curative surgery for colorectal cancer: A systematic review and meta-analysis.

Almasaudi AS, McSorley ST, Edwards CA, McMillan DC.

Crit Rev Oncol Hematol. 2018 Jan;121:68-73. doi: 10.1016/j.critrevonc.2017.12.004. Epub 2017 Dec 7. Review.


The role of the systemic inflammatory response in predicting outcomes in patients with operable cancer: Systematic review and meta-analysis.

Dolan RD, Lim J, McSorley ST, Horgan PG, McMillan DC.

Sci Rep. 2017 Dec 1;7(1):16717. doi: 10.1038/s41598-017-16955-5.


The relationship between 18 F-FDG-PETCT-derived markers of tumour metabolism and systemic inflammation in patients with recurrent disease following surgery for colorectal cancer.

McSorley ST, Khor BY, Tsang K, Colville D, Han S, Horgan PG, McMillan DC.

Colorectal Dis. 2018 May;20(5):407-415. doi: 10.1111/codi.13973.


Sacral neuromodulation for faecal incontinence - 10 years' experience at a Scottish tertiary centre.

Koh H, McSorley S, Hunt S, Quinn M, MacKay G, Anderson J.

Surgeon. 2017 Oct 25. pii: S1479-666X(17)30132-4. doi: 10.1016/j.surge.2017.08.006. [Epub ahead of print]


Staging the tumor and staging the host: A two centre, two country comparison of systemic inflammatory responses of patients undergoing resection of primary operable colorectal cancer.

Park JH, Ishizuka M, McSorley ST, Kubota K, Roxburgh CSD, Nagata H, Takagi K, Iwasaki Y, Aoki T, Horgan PG, McMillan DC.

Am J Surg. 2017 Sep 20. pii: S0002-9610(17)31190-X. doi: 10.1016/j.amjsurg.2017.08.044. [Epub ahead of print]


T cell expression of IL-18R and DR3 is essential for non-cognate stimulation of Th1 cells and optimal clearance of intracellular bacteria.

Pham OH, O'Donnell H, Al-Shamkhani A, Kerrinnes T, Tsolis RM, McSorley SJ.

PLoS Pathog. 2017 Aug 17;13(8):e1006566. doi: 10.1371/journal.ppat.1006566. eCollection 2017 Aug.


CCR7 Deficiency Allows Accelerated Clearance of Chlamydia from the Female Reproductive Tract.

Li LX, Labuda JC, Imai DM, Griffey SM, McSorley SJ.

J Immunol. 2017 Oct 1;199(7):2547-2554. doi: 10.4049/jimmunol.1601314. Epub 2017 Aug 11.


Corpus of deaf speech for acoustic and speech production research.

Mendel LL, Lee S, Pousson M, Patro C, McSorley S, Banerjee B, Najnin S, Kapourchali MH.

J Acoust Soc Am. 2017 Jul;142(1):EL102. doi: 10.1121/1.4994288.


Attitudes of surgeons to the use of postoperative markers of the systemic inflammatory response following elective surgery.

Dolan RD, McSorley ST, McMillan DC, Horgan PG.

Ann Med Surg (Lond). 2017 Jul 20;21:14-19. doi: 10.1016/j.amsu.2017.07.046. eCollection 2017 Sep.


Dual Immunization with SseB/Flagellin Provides Enhanced Protection against Salmonella Infection Mediated by Circulating Memory Cells.

Lee SJ, Benoun J, Sheridan BS, Fogassy Z, Pham O, Pham QM, Puddington L, McSorley SJ.

J Immunol. 2017 Aug 15;199(4):1353-1361. doi: 10.4049/jimmunol.1601357. Epub 2017 Jul 14.


Clinicopathological Determinants of an Elevated Systemic Inflammatory Response Following Elective Potentially Curative Resection for Colorectal Cancer.

Watt DG, Ramanathan ML, McSorley ST, Walley K, Park JH, Horgan PG, McMillan DC.

Ann Surg Oncol. 2017 Sep;24(9):2588-2594. doi: 10.1245/s10434-017-5987-z. Epub 2017 Jul 10.


The role of the systemic inflammatory response in predicting outcomes in patients with advanced inoperable cancer: Systematic review and meta-analysis.

Dolan RD, McSorley ST, Horgan PG, Laird B, McMillan DC.

Crit Rev Oncol Hematol. 2017 Aug;116:134-146. doi: 10.1016/j.critrevonc.2017.06.002. Epub 2017 Jun 9. Review.


Interpreting iron studies.

Kelly AU, McSorley ST, Patel P, Talwar D.

BMJ. 2017 Jun 15;357:j2513. doi: 10.1136/bmj.j2513. No abstract available. Erratum in: BMJ. 2017 Jun 29;357:j3175.


The relationship between tumour stage, systemic inflammation, body composition and survival in patients with colorectal cancer.

McSorley ST, Black DH, Horgan PG, McMillan DC.

Clin Nutr. 2018 Aug;37(4):1279-1285. doi: 10.1016/j.clnu.2017.05.017. Epub 2017 May 19.


U-Omp19 from Brucella abortus Is a Useful Adjuvant for Vaccine Formulations against Salmonella Infection in Mice.

Risso GS, Carabajal MV, Bruno LA, Ibañez AE, Coria LM, Pasquevich KA, Lee SJ, McSorley SJ, Briones G, Cassataro J.

Front Immunol. 2017 Feb 17;8:171. doi: 10.3389/fimmu.2017.00171. eCollection 2017.


The Impact of Preoperative Dexamethasone on the Magnitude of the Postoperative Systemic Inflammatory Response and Complications Following Surgery for Colorectal Cancer.

McSorley ST, Roxburgh CSD, Horgan PG, McMillan DC.

Ann Surg Oncol. 2017 Aug;24(8):2104-2112. doi: 10.1245/s10434-017-5817-3. Epub 2017 Mar 1.


Examination of a CRP first approach for the detection of postoperative complications in patients undergoing surgery for colorectal cancer: A pragmatic study.

McSorley ST, Khor BY, MacKay GJ, Horgan PG, McMillan DC.

Medicine (Baltimore). 2017 Feb;96(7):e6133. doi: 10.1097/MD.0000000000006133.


A Protective Vaccine against Chlamydia Genital Infection Using Vault Nanoparticles without an Added Adjuvant.

Jiang J, Liu G, Kickhoefer VA, Rome LH, Li LX, McSorley SJ, Kelly KA.

Vaccines (Basel). 2017 Jan 19;5(1). pii: E3. doi: 10.3390/vaccines5010003.


Collateral Damage: Detrimental Effect of Antibiotics on the Development of Protective Immune Memory.

Benoun JM, Labuda JC, McSorley SJ.

MBio. 2016 Dec 20;7(6). pii: e01520-16. doi: 10.1128/mBio.01520-16. Review.


The relationship between systemic inflammation and stoma formation following anterior resection for rectal cancer: A cross-sectional study.

Khor BY, McSorley ST, Horgan PG, McMillan DC.

Int J Surg. 2017 Jan;37:79-84. doi: 10.1016/j.ijsu.2016.12.010. Epub 2016 Dec 9.


The Pretreatment Systemic Inflammatory Response is an Important Determinant of Poor Pathologic Response for Patients Undergoing Neoadjuvant Therapy for Rectal Cancer.

Dreyer SB, Powell AG, McSorley ST, Waterston A, Going JJ, Edwards J, McMillan DC, Horgan PG.

Ann Surg Oncol. 2017 May;24(5):1295-1303. doi: 10.1245/s10434-016-5684-3. Epub 2016 Nov 21.


A Postoperative Systemic Inflammation Score Predicts Short- and Long-Term Outcomes in Patients Undergoing Surgery for Colorectal Cancer.

Watt DG, McSorley ST, Park JH, Horgan PG, McMillan DC.

Ann Surg Oncol. 2017 Apr;24(4):1100-1109. doi: 10.1245/s10434-016-5659-4. Epub 2016 Nov 7.


Comment on "The Important Role for Intravenous Iron in Perioperative Patient Blood Management in Major Abdominal Surgery: A Randomized Controlled Trial".

McSorley ST, Mansouri D, Horgan PG, McMillan DC.

Ann Surg. 2018 Mar;267(3):e49. doi: 10.1097/SLA.0000000000002053. No abstract available.


Salmonella Infection Enhances Erythropoietin Production by the Kidney and Liver, Which Correlates with Elevated Bacterial Burdens.

Li LX, Benoun JM, Weiskopf K, Garcia KC, McSorley SJ.

Infect Immun. 2016 Sep 19;84(10):2833-41. doi: 10.1128/IAI.00337-16. Print 2016 Oct.


Quantitative data on the magnitude of the systemic inflammatory response and its relationship with serum measures of iron status.

McSorley ST, Jones I, McMillan DC, Talwar D.

Transl Res. 2016 Oct;176:119-26. doi: 10.1016/j.trsl.2016.05.004. Epub 2016 Jun 6.


Adhesion Molecules Associated with Female Genital Tract Infection.

Qualai J, Cantero J, Li LX, Carrascosa JM, Cabré E, Dern O, Sumoy L, Requena G, McSorley SJ, Genescà M.

PLoS One. 2016 Jun 7;11(6):e0156605. doi: 10.1371/journal.pone.0156605. eCollection 2016.


Expression of CD11c Is Associated with Unconventional Activated T Cell Subsets with High Migratory Potential.

Qualai J, Li LX, Cantero J, Tarrats A, Fernández MA, Sumoy L, Rodolosse A, McSorley SJ, Genescà M.

PLoS One. 2016 Apr 27;11(4):e0154253. doi: 10.1371/journal.pone.0154253. eCollection 2016.


Postoperative Systemic Inflammatory Response, Complication Severity, and Survival Following Surgery for Colorectal Cancer.

McSorley ST, Watt DG, Horgan PG, McMillan DC.

Ann Surg Oncol. 2016 Sep;23(9):2832-40. doi: 10.1245/s10434-016-5204-5. Epub 2016 Mar 25.


NOD1 and NOD2 signalling links ER stress with inflammation.

Keestra-Gounder AM, Byndloss MX, Seyffert N, Young BM, Chávez-Arroyo A, Tsai AY, Cevallos SA, Winter MG, Pham OH, Tiffany CR, de Jong MF, Kerrinnes T, Ravindran R, Luciw PA, McSorley SJ, Bäumler AJ, Tsolis RM.

Nature. 2016 Apr 21;532(7599):394-7. doi: 10.1038/nature17631. Epub 2016 Mar 23.


The impact of preoperative corticosteroids on the systemic inflammatory response and postoperative complications following surgery for gastrointestinal cancer: A systematic review and meta-analysis.

McSorley ST, Horgan PG, McMillan DC.

Crit Rev Oncol Hematol. 2016 May;101:139-50. doi: 10.1016/j.critrevonc.2016.03.011. Epub 2016 Mar 10. Review.


Absence of TLR11 in Mice Does Not Confer Susceptibility to Salmonella Typhi.

Song J, Wilhelm CL, Wangdi T, Maira-Litran T, Lee SJ, Raetz M, Sturge CR, Mirpuri J, Pei J, Grishin NV, McSorley SJ, Gewirtz AT, Bäumler AJ, Pier GB, Galán JE, Yarovinsky F.

Cell. 2016 Feb 25;164(5):827-8. doi: 10.1016/j.cell.2016.02.015. No abstract available.


Contaminated water delivery as a simple and effective method of experimental Salmonella infection.

O'Donnell H, Pham OH, Benoun JM, Ravesloot-Chávez MM, McSorley SJ.

Future Microbiol. 2015;10(10):1615-27. doi: 10.2217/fmb.15.93. Epub 2015 Oct 6.


Transient Loss of Protection Afforded by a Live Attenuated Non-typhoidal Salmonella Vaccine in Mice Co-infected with Malaria.

Mooney JP, Lee SJ, Lokken KL, Nanton MR, Nuccio SP, McSorley SJ, Tsolis RM.

PLoS Negl Trop Dis. 2015 Sep 14;9(9):e0004027. doi: 10.1371/journal.pntd.0004027. eCollection 2015.


Enhanced Recovery After Surgery: Which Components, If Any, Impact on The Systemic Inflammatory Response Following Colorectal Surgery?: A Systematic Review.

Watt DG, McSorley ST, Horgan PG, McMillan DC.

Medicine (Baltimore). 2015 Sep;94(36):e1286. doi: 10.1097/MD.0000000000001286.


The impact of the type and severity of postoperative complications on long-term outcomes following surgery for colorectal cancer: A systematic review and meta-analysis.

McSorley ST, Horgan PG, McMillan DC.

Crit Rev Oncol Hematol. 2016 Jan;97:168-77. doi: 10.1016/j.critrevonc.2015.08.013. Epub 2015 Aug 14. Review.


Salmonella Infection Drives Promiscuous B Cell Activation Followed by Extrafollicular Affinity Maturation.

Di Niro R, Lee SJ, Vander Heiden JA, Elsner RA, Trivedi N, Bannock JM, Gupta NT, Kleinstein SH, Vigneault F, Gilbert TJ, Meffre E, McSorley SJ, Shlomchik MJ.

Immunity. 2015 Jul 21;43(1):120-31. doi: 10.1016/j.immuni.2015.06.013. Epub 2015 Jul 14.


Divergent behavior of mucosal memory T cells.

Pham OH, McSorley SJ.

Mucosal Immunol. 2015 Jul;8(4):731-4. doi: 10.1038/mi.2015.52. Epub 2015 Jun 10.


Postoperative C-reactive protein measurement predicts the severity of complications following surgery for colorectal cancer.

McSorley ST, Ramanathan ML, Horgan PG, McMillan DC.

Int J Colorectal Dis. 2015 Jul;30(7):913-7. doi: 10.1007/s00384-015-2229-3. Epub 2015 Apr 29.


A re-evaluation of the role of B cells in protective immunity to Chlamydia infection.

Li LX, McSorley SJ.

Immunol Lett. 2015 Apr;164(2):88-93. doi: 10.1016/j.imlet.2015.02.004. Epub 2015 Feb 20. Review.


Protective host immune responses to Salmonella infection.

Pham OH, McSorley SJ.

Future Microbiol. 2015;10(1):101-10. doi: 10.2217/fmb.14.98. Review.


Salmonella as a model for non-cognate Th1 cell stimulation.

O'Donnell H, McSorley SJ.

Front Immunol. 2014 Dec 10;5:621. doi: 10.3389/fimmu.2014.00621. eCollection 2014. Review.


Rapid CD4+ T-cell responses to bacterial flagellin require dendritic cell expression of Syk and CARD9.

Atif SM, Lee SJ, Li LX, Uematsu S, Akira S, Gorjestani S, Lin X, Schweighoffer E, Tybulewicz VL, McSorley SJ.

Eur J Immunol. 2015 Feb;45(2):513-24. doi: 10.1002/eji.201444744. Epub 2014 Dec 8.


Direct visualization of endogenous Salmonella-specific B cells reveals a marked delay in clonal expansion and germinal center development.

Nanton MR, Lee SJ, Atif SM, Nuccio SP, Taylor JJ, Bäumler AJ, Way SS, McSorley SJ.

Eur J Immunol. 2015 Feb;45(2):428-41. doi: 10.1002/eji.201444540. Epub 2014 Nov 20.


Introduction to special issue on microbiome influences on host immunity.

McSorley SJ, Khoruts A.

Immunol Lett. 2014 Dec;162(2 Pt A):1-2. doi: 10.1016/j.imlet.2014.08.006. Epub 2014 Aug 12. No abstract available.


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