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Items: 1 to 50 of 178

1.

Low-dose IL-2 induces CD56bright NK regulation of T cells via NKp44 and NKp46.

McQuaid SL, Loughran ST, Power PA, Maguire P, Szczygiel A, Johnson PA.

Clin Exp Immunol. 2020 Jan 27. doi: 10.1111/cei.13422. [Epub ahead of print]

PMID:
31989589
2.

Alcohol intake, tobacco smoking, and esophageal adenocarcinoma survival: a molecular pathology epidemiology cohort study.

McCain RS, McManus DT, McQuaid S, James JA, Salto-Tellez M, Reid NB, Craig S, Chisambo C, Bingham V, McCarron E, Parkes E, Turkington RC, Coleman HG.

Cancer Causes Control. 2020 Jan;31(1):1-11. doi: 10.1007/s10552-019-01247-2. Epub 2019 Nov 30.

3.

Comparison of Molecular Assays for HPV Testing in Oropharyngeal Squamous Cell Carcinomas: A Population-Based Study in Northern Ireland.

Craig SG, Anderson LA, Moran M, Graham L, Currie K, Rooney K, Robinson M, Bingham V, Cuschieri KS, McQuaid S, Schache AG, Jones TM, McCance D, Salto-Tellez M, McDade SS, James JA.

Cancer Epidemiol Biomarkers Prev. 2020 Jan;29(1):31-38. doi: 10.1158/1055-9965.EPI-19-0538. Epub 2019 Oct 30.

PMID:
31666283
4.

In-vivo metabolic studies of regional adipose tissue.

Melvin A, McQuaid SE.

Cardiovasc Endocrinol Metab. 2018 Nov 14;7(4):75-79. doi: 10.1097/XCE.0000000000000154. eCollection 2018 Dec. Review.

5.

A Novel Role for Cathepsin S as a Potential Biomarker in Triple Negative Breast Cancer.

Wilkinson RDA, Burden RE, McDowell SH, McArt DG, McQuaid S, Bingham V, Williams R, Cox ÓT, O'Connor R, McCabe N, Kennedy RD, Buckley NE, Scott CJ.

J Oncol. 2019 Jun 27;2019:3980273. doi: 10.1155/2019/3980273. eCollection 2019.

6.

Adverse Events in Genetic Testing: The Fourth Case Series.

Farmer MB, Bonadies DC, Mahon SM, Baker MJ, Ghate SM, Munro C, Nagaraj CB, Besser AG, Bui K, Csuy CM, Kirkpatrick B, McCarty AJ, McQuaid SW, Sebastian J, Sternen DL, Walsh LK, Matloff ET.

Cancer J. 2019 Jul/Aug;25(4):231-236. doi: 10.1097/PPO.0000000000000391.

PMID:
31335384
7.

Iodine status of teenage girls on the island of Ireland.

Mullan K, Hamill L, Doolan K, Young I, Smyth P, Flynn A, Walton J, Meharg AA, Carey M, McKernan C, Bell M, Black N, Graham U, McCance D, McHugh C, McMullan P, McQuaid S, O'Loughlin A, Tuthill A, Bath SC, Rayman M, Woodside JV.

Eur J Nutr. 2019 Jul 18. doi: 10.1007/s00394-019-02037-x. [Epub ahead of print]

PMID:
31321499
8.

Leydig Cell Hyperplasia Mimicking a Testicular Tumour in a Patient with Klinefelter Syndrome.

Newman C, Connolly S, MacEneaney O, O'Keane C, McQuaid SE.

Eur J Case Rep Intern Med. 2019 Jun 7;6(6):001129. doi: 10.12890/2019_001129. eCollection 2019.

9.

Bilateral Plantar Fibromatosis

Newman C, McQuaid SE.

Ir Med J. 2019 Apr 11;112(4):919.

PMID:
31243948
10.

NUP98 - a novel predictor of response to anthracycline-based chemotherapy in triple negative breast cancer.

Mullan PB, Bingham V, Haddock P, Irwin GW, Kay E, McQuaid S, Buckley NE.

BMC Cancer. 2019 Apr 2;19(1):236. doi: 10.1186/s12885-019-5407-9.

11.

Recommendations for determining HPV status in patients with oropharyngeal cancers under TNM8 guidelines: a two-tier approach.

Craig SG, Anderson LA, Schache AG, Moran M, Graham L, Currie K, Rooney K, Robinson M, Upile NS, Brooker R, Mesri M, Bingham V, McQuaid S, Jones T, McCance DJ, Salto-Tellez M, McDade SS, James JA.

Br J Cancer. 2019 Apr;120(8):827-833. doi: 10.1038/s41416-019-0414-9. Epub 2019 Mar 20.

12.

Immune activation by DNA damage predicts response to chemotherapy and survival in oesophageal adenocarcinoma.

Turkington RC, Knight LA, Blayney JK, Secrier M, Douglas R, Parkes EE, Sutton EK, Stevenson L, McManus D, Halliday S, McCavigan AM, Logan GE, Walker SM, Steele CJ, Perner J, Bornschein J, MacRae S, Miremadi A, McCarron E, McQuaid S, Arthur K, James JA, Eatock MM, O'Neill R, Noble F, Underwood TJ, Harkin DP, Salto-Tellez M, Fitzgerald RC, Kennedy RD; Oesophageal Cancer Clinical and Molecular Stratification (OCCAMS) Study Group.

Gut. 2019 Nov;68(11):1918-1927. doi: 10.1136/gutjnl-2018-317624. Epub 2019 Mar 9.

13.

Automated Tumour Recognition and Digital Pathology Scoring Unravels New Role for PD-L1 in Predicting Good Outcome in ER-/HER2+ Breast Cancer.

Humphries MP, Hynes S, Bingham V, Cougot D, James J, Patel-Socha F, Parkes EE, Blayney JK, O'Rorke MA, Irwin GW, McArt DG, Kennedy RD, Mullan PB, McQuaid S, Salto-Tellez M, Buckley NE.

J Oncol. 2018 Dec 17;2018:2937012. doi: 10.1155/2018/2937012. eCollection 2018.

14.

Sex hormone receptor expression and survival in esophageal adenocarcinoma: a prospective cohort study.

McMenamin ÚC, Trainor J, Coleman HG, McManus DT, McQuaid S, Bingham V, James J, Salto-Tellez M, Johnston BT, Turkington RC.

Oncotarget. 2018 Oct 19;9(82):35300-35312. doi: 10.18632/oncotarget.26236. eCollection 2018 Oct 19.

15.

High PTGS2 expression in post-neoadjuvant chemotherapy-treated oesophageal adenocarcinoma is associated with improved survival: a population-based cohort study.

Spence AD, Trainor J, McMenamin Ú, Turkington RC, McQuaid S, Bingham V, James J, Salto-Tellez M, McManus DT, Johnston BT, Cardwell CR, Coleman HG.

Histopathology. 2019 Mar;74(4):587-596. doi: 10.1111/his.13786. Epub 2019 Jan 25.

PMID:
30408225
16.

Punctate MLH1 mismatch repair immunostaining in colorectal cancer.

Loughrey MB, Dunne PD, Coleman HG, McQuaid S, James JA.

Histopathology. 2019 Apr;74(5):795-797. doi: 10.1111/his.13780. Epub 2019 Feb 17. No abstract available.

PMID:
30379344
17.

Vitamin D receptor as a marker of prognosis in oesophageal adenocarcinoma: a prospective cohort study.

McCain S, Trainor J, McManus DT, McMenamin ÚC, McQuaid S, Bingham V, James JA, Salto-Tellez M, Turkington RC, Coleman HG.

Oncotarget. 2018 Sep 28;9(76):34347-34356. doi: 10.18632/oncotarget.26151. eCollection 2018 Sep 28.

18.

Critical Appraisal of Programmed Death Ligand 1 Reflex Diagnostic Testing: Current Standards and Future Opportunities.

Humphries MP, McQuaid S, Craig SG, Bingham V, Maxwell P, Maurya M, McLean F, Sampson J, Higgins P, Greene C, James J, Salto-Tellez M.

J Thorac Oncol. 2019 Jan;14(1):45-53. doi: 10.1016/j.jtho.2018.09.025. Epub 2018 Oct 6.

19.

Influenza infection directly alters innate IL-23 and IL-12p70 and subsequent IL-17A and IFN-γ responses to pneumococcus in vitro in human monocytes.

Loughran ST, Power PA, Maguire PT, McQuaid SL, Buchanan PJ, Jonsdottir I, Newman RW, Harvey R, Johnson PA.

PLoS One. 2018 Sep 7;13(9):e0203521. doi: 10.1371/journal.pone.0203521. eCollection 2018.

20.

Corrigendum: Haemagglutinin-neuraminidase from HPIV3 mediates human NK regulation of T cell proliferation via NKp44 and NKp46.

McQuaid S, Loughran S, Power P, Maguire P, Walls D, Grazia Cusi M, Orvell C, Johnson P.

J Gen Virol. 2018 Sep;99(9):1344. doi: 10.1099/jgv.0.001126. No abstract available.

PMID:
30176163
21.

Macrophages and Dendritic Cells Are the Predominant Cells Infected in Measles in Humans.

Allen IV, McQuaid S, Penalva R, Ludlow M, Duprex WP, Rima BK.

mSphere. 2018 May 9;3(3). pii: e00570-17. doi: 10.1128/mSphere.00570-17. eCollection 2018 May-Jun.

22.

Microvascular diabetes complications in a specialist young adult diabetes service.

Melvin A, Redahan L, Hatunic M, McQuaid SE.

Ir J Med Sci. 2019 Feb;188(1):129-134. doi: 10.1007/s11845-018-1827-9. Epub 2018 May 7.

PMID:
29732503
23.

Glucose transporter 1 expression as a marker of prognosis in oesophageal adenocarcinoma.

Blayney JK, Cairns L, Li G, McCabe N, Stevenson L, Peters CJ, Reid NB, Spence VJ, Chisambo C, McManus D, James J, McQuaid S, Craig S, Arthur K, McArt D, Ong CJ, Lao-Sirieix P, Hamilton P, Salto-Tellez M, Eatock M, Coleman HG, Fitzgerald RC, Kennedy RD, Turkington RC; Oesophageal Cancer Clinical and Molecular Stratification (OCCAMS) Study Group.

Oncotarget. 2018 Apr 6;9(26):18518-18528. doi: 10.18632/oncotarget.24906. eCollection 2018 Apr 6.

24.

Haemagglutinin-neuraminidase from HPIV3 mediates human NK regulation of T cell proliferation via NKp44 and NKp46.

McQuaid S, Loughran S, Power P, Maguire P, Walls D, Cusi MG, Orvell C, Johnson P.

J Gen Virol. 2018 Jun;99(6):763-767. doi: 10.1099/jgv.0.001070. Epub 2018 Apr 23. Erratum in: J Gen Virol. 2018 Sep;99(9):1344.

PMID:
29683419
25.

A gene signature associated with PTEN activation defines good prognosis intermediate risk prostate cancer cases.

Ong CW, Maxwell P, Alvi MA, McQuaid S, Waugh D, Mills I, Salto-Tellez M.

J Pathol Clin Res. 2018 Apr;4(2):103-113. doi: 10.1002/cjp2.94. Epub 2018 Feb 28.

26.

Validation of the systematic scoring of immunohistochemically stained tumour tissue microarrays using QuPath digital image analysis.

Loughrey MB, Bankhead P, Coleman HG, Hagan RS, Craig S, McCorry AMB, Gray RT, McQuaid S, Dunne PD, Hamilton PW, James JA, Salto-Tellez M.

Histopathology. 2018 Aug;73(2):327-338. doi: 10.1111/his.13516. Epub 2018 May 21.

PMID:
29575153
27.

Bcl-xL as a poor prognostic biomarker and predictor of response to adjuvant chemotherapy specifically in BRAF-mutant stage II and III colon cancer.

Dunne PD, Coleman HG, Bankhead P, Alderdice M, Gray RT, McQuaid S, Bingham V, Loughrey MB, James JA, McCorry AMB, Gilmore A, Holohan C, Klingbiel D, Tejpar S, Johnston PG, McArt DG, Di Nicolantonio F, Longley DB, Lawler M.

Oncotarget. 2018 Feb 13;9(17):13834-13847. doi: 10.18632/oncotarget.24481. eCollection 2018 Mar 2.

28.

Septal penetration correction in I-131 imaging following thyroid cancer treatment.

Barrack F, Scuffham J, McQuaid S.

Phys Med Biol. 2018 Mar 27;63(7):075012. doi: 10.1088/1361-6560/aab13a.

PMID:
29465414
29.

Practical guide for the comparison of two next-generation sequencing systems for solid tumour analysis in a universal healthcare system.

Maxwell P, Hynes SO, Fuchs M, Craig S, McGready C, McLean F, McQuaid S, James J, Salto-Tellez M.

J Clin Pathol. 2019 Mar;72(3):225-231. doi: 10.1136/jclinpath-2017-204917. Epub 2018 Jan 31.

PMID:
29386326
30.

Recurrent hospitalisations in a rare case of hemicorporectomy: a challenging case for medical management.

Thakur A, Elliott B, Naik R, Khan N, McQuaid S, Arsene C.

BMJ Case Rep. 2018 Jan 4;2018. pii: bcr-2017-222375. doi: 10.1136/bcr-2017-222375.

31.

Needle-free delivery of measles virus vaccine to the lower respiratory tract of non-human primates elicits optimal immunity and protection.

de Swart RL, de Vries RD, Rennick LJ, van Amerongen G, McQuaid S, Verburgh RJ, Yüksel S, de Jong A, Lemon K, Nguyen DT, Ludlow M, Osterhaus ADME, Duprex WP.

NPJ Vaccines. 2017 Aug 1;2:22. doi: 10.1038/s41541-017-0022-8. eCollection 2017.

32.

Integrated tumor identification and automated scoring minimizes pathologist involvement and provides new insights to key biomarkers in breast cancer.

Bankhead P, Fernández JA, McArt DG, Boyle DP, Li G, Loughrey MB, Irwin GW, Harkin DP, James JA, McQuaid S, Salto-Tellez M, Hamilton PW.

Lab Invest. 2018 Jan;98(1):15-26. doi: 10.1038/labinvest.2017.131. Epub 2017 Dec 18.

33.

RNAscope in situ hybridization confirms mRNA integrity in formalin-fixed, paraffin-embedded cancer tissue samples.

Bingham V, McIlreavey L, Greene C, O'Doherty E, Clarke R, Craig S, Salto-Tellez M, McQuaid S, Lewis C, James J.

Oncotarget. 2017 Oct 16;8(55):93392-93403. doi: 10.18632/oncotarget.21851. eCollection 2017 Nov 7.

34.

QuPath: Open source software for digital pathology image analysis.

Bankhead P, Loughrey MB, Fernández JA, Dombrowski Y, McArt DG, Dunne PD, McQuaid S, Gray RT, Murray LJ, Coleman HG, James JA, Salto-Tellez M, Hamilton PW.

Sci Rep. 2017 Dec 4;7(1):16878. doi: 10.1038/s41598-017-17204-5.

35.

Validation of a Metastatic Assay using biopsies to improve risk stratification in patients with prostate cancer treated with radical radiation therapy.

Jain S, Lyons CA, Walker SM, McQuaid S, Hynes SO, Mitchell DM, Pang B, Logan GE, McCavigan AM, O'Rourke D, McArt DG, McDade SS, Mills IG, Prise KM, Knight LA, Steele CJ, Medlow PW, Berge V, Katz B, Loblaw DA, Harkin DP, James JA, O'Sullivan JM, Kennedy RD, Waugh DJ.

Ann Oncol. 2018 Jan 1;29(1):215-222. doi: 10.1093/annonc/mdx637.

36.

Clinical applications of textural analysis in non-small cell lung cancer.

Phillips I, Ajaz M, Ezhil V, Prakash V, Alobaidli S, McQuaid SJ, South C, Scuffham J, Nisbet A, Evans P.

Br J Radiol. 2018 Jan;91(1081):20170267. doi: 10.1259/bjr.20170267. Epub 2017 Oct 27. Review.

37.

Natural killer-like signature observed post therapy in locally advanced rectal cancer is a determinant of pathological response and improved survival.

Alderdice M, Dunne PD, Cole AJ, O'Reilly PG, McArt DG, Bingham V, Fuchs MA, McQuaid S, Loughrey MB, Murray GI, Samuel LM, Lawler M, Wilson RH, Salto-Tellez M, Coyle VM.

Mod Pathol. 2017 Sep;30(9):1287-1298. doi: 10.1038/modpathol.2017.47. Epub 2017 Jun 16.

38.

Factors influencing the robustness of P-value measurements in CT texture prognosis studies.

McQuaid S, Scuffham J, Alobaidli S, Prakash V, Ezhil V, Nisbet A, South C, Evans P.

Phys Med Biol. 2017 Jul 7;62(13):5403-5416. doi: 10.1088/1361-6560/aa6cf2. Epub 2017 Jun 12.

PMID:
28604371
39.

Molecular profiling of signet ring cell colorectal cancer provides a strong rationale for genomic targeted and immune checkpoint inhibitor therapies.

Alvi MA, Loughrey MB, Dunne P, McQuaid S, Turkington R, Fuchs MA, McGready C, Bingham V, Pang B, Moore W, Maxwell P, Lawler M, James JA, Murray GI, Wilson RH, Salto-Tellez M.

Br J Cancer. 2017 Jul 11;117(2):203-209. doi: 10.1038/bjc.2017.168. Epub 2017 Jun 8.

40.

Statin use, candidate mevalonate pathway biomarkers, and colon cancer survival in a population-based cohort study.

Gray RT, Loughrey MB, Bankhead P, Cardwell CR, McQuaid S, O'Neill RF, Arthur K, Bingham V, McGready C, Gavin AT, James JA, Hamilton PW, Salto-Tellez M, Murray LJ, Coleman HG.

Br J Cancer. 2017 Jun 6;116(12):1652-1659. doi: 10.1038/bjc.2017.139. Epub 2017 May 18.

41.

Evaluation of PTGS2 Expression, PIK3CA Mutation, Aspirin Use and Colon Cancer Survival in a Population-Based Cohort Study.

Gray RT, Cantwell MM, Coleman HG, Loughrey MB, Bankhead P, McQuaid S, O'Neill RF, Arthur K, Bingham V, McGready C, Gavin AT, Cardwell CR, Johnston BT, James JA, Hamilton PW, Salto-Tellez M, Murray LJ.

Clin Transl Gastroenterol. 2017 Apr 27;8(4):e91. doi: 10.1038/ctg.2017.18.

42.

Back to the future: routine morphological assessment of the tumour microenvironment is prognostic in stage II/III colon cancer in a large population-based study.

Hynes SO, Coleman HG, Kelly PJ, Irwin S, O'Neill RF, Gray RT, McGready C, Dunne PD, McQuaid S, James JA, Salto-Tellez M, Loughrey MB.

Histopathology. 2017 Jul;71(1):12-26. doi: 10.1111/his.13181. Epub 2017 Apr 3.

PMID:
28165633
43.

Transcriptional upregulation of c-MET is associated with invasion and tumor budding in colorectal cancer.

Bradley CA, Dunne PD, Bingham V, McQuaid S, Khawaja H, Craig S, James J, Moore WL, McArt DG, Lawler M, Dasgupta S, Johnston PG, Van Schaeybroeck S.

Oncotarget. 2016 Nov 29;7(48):78932-78945. doi: 10.18632/oncotarget.12933.

44.

Deep sequencing reveals persistence of cell-associated mumps vaccine virus in chronic encephalitis.

Morfopoulou S, Mee ET, Connaughton SM, Brown JR, Gilmour K, Chong WK, Duprex WP, Ferguson D, Hubank M, Hutchinson C, Kaliakatsos M, McQuaid S, Paine S, Plagnol V, Ruis C, Virasami A, Zhan H, Jacques TS, Schepelmann S, Qasim W, Breuer J.

Acta Neuropathol. 2017 Jan;133(1):139-147. doi: 10.1007/s00401-016-1629-y. Epub 2016 Oct 21.

45.

Activation of STING-Dependent Innate Immune Signaling By S-Phase-Specific DNA Damage in Breast Cancer.

Parkes EE, Walker SM, Taggart LE, McCabe N, Knight LA, Wilkinson R, McCloskey KD, Buckley NE, Savage KI, Salto-Tellez M, McQuaid S, Harte MT, Mullan PB, Harkin DP, Kennedy RD.

J Natl Cancer Inst. 2016 Oct 5;109(1). doi: 10.1093/jnci/djw199. Print 2017 Jan.

46.

Building a 'Repository of Science': The importance of integrating biobanks within molecular pathology programmes.

Lewis C, McQuaid S, Hamilton PW, Salto-Tellez M, McArt D, James JA.

Eur J Cancer. 2016 Nov;67:191-199. doi: 10.1016/j.ejca.2016.08.009. Epub 2016 Sep 24. Review.

PMID:
27677055
47.

Thromboxane A2 receptor (TBXA2R) is a potent survival factor for triple negative breast cancers (TNBCs).

Orr K, Buckley NE, Haddock P, James C, Parent JL, McQuaid S, Mullan PB.

Oncotarget. 2016 Aug 23;7(34):55458-55472. doi: 10.18632/oncotarget.10969.

48.

Measles Virus Host Invasion and Pathogenesis.

Laksono BM, de Vries RD, McQuaid S, Duprex WP, de Swart RL.

Viruses. 2016 Jul 28;8(8). pii: E210. doi: 10.3390/v8080210. Review.

49.

Quantification of HER2 heterogeneity in breast cancer-implications for identification of sub-dominant clones for personalised treatment.

Buckley NE, Forde C, McArt DG, Boyle DP, Mullan PB, James JA, Maxwell P, McQuaid S, Salto-Tellez M.

Sci Rep. 2016 Mar 21;6:23383. doi: 10.1038/srep23383.

50.

A BRCA1 deficient, NFκB driven immune signal predicts good outcome in triple negative breast cancer.

Buckley NE, Haddock P, De Matos Simoes R, Parkes E, Irwin G, Emmert-Streib F, McQuaid S, Kennedy R, Mullan P.

Oncotarget. 2016 Apr 12;7(15):19884-96. doi: 10.18632/oncotarget.7865.

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