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Items: 36

1.

Functional genomics identifies specific vulnerabilities in PTEN-deficient breast cancer.

Tang YC, Ho SC, Tan E, Ng AWT, McPherson JR, Goh GYL, Teh BT, Bard F, Rozen SG.

Breast Cancer Res. 2018 Mar 22;20(1):22. doi: 10.1186/s13058-018-0949-3.

2.

Whole-Genome and Epigenomic Landscapes of Etiologically Distinct Subtypes of Cholangiocarcinoma.

Jusakul A, Cutcutache I, Yong CH, Lim JQ, Huang MN, Padmanabhan N, Nellore V, Kongpetch S, Ng AWT, Ng LM, Choo SP, Myint SS, Thanan R, Nagarajan S, Lim WK, Ng CCY, Boot A, Liu M, Ong CK, Rajasegaran V, Lie S, Lim AST, Lim TH, Tan J, Loh JL, McPherson JR, Khuntikeo N, Bhudhisawasdi V, Yongvanit P, Wongkham S, Totoki Y, Nakamura H, Arai Y, Yamasaki S, Chow PK, Chung AYF, Ooi LLPJ, Lim KH, Dima S, Duda DG, Popescu I, Broet P, Hsieh SY, Yu MC, Scarpa A, Lai J, Luo DX, Carvalho AL, Vettore AL, Rhee H, Park YN, Alexandrov LB, Gordân R, Rozen SG, Shibata T, Pairojkul C, Teh BT, Tan P.

Cancer Discov. 2017 Oct;7(10):1116-1135. doi: 10.1158/2159-8290.CD-17-0368. Epub 2017 Jun 30.

3.

A formalin-fixed paraffin-embedded (FFPE)-based prognostic signature to predict metastasis in clinically low risk stage I/II microsatellite stable colorectal cancer.

Low YS, Blöcker C, McPherson JR, Tang SA, Cheng YY, Wong JYS, Chua C, Lim TKH, Tang CL, Chew MH, Tan P, Tan IB, Rozen SG, Cheah PY.

Cancer Lett. 2017 Sep 10;403:13-20. doi: 10.1016/j.canlet.2017.05.031. Epub 2017 Jun 15.

PMID:
28624625
4.

Transcription-associated mutation of lasR in Pseudomonas aeruginosa.

Wang C, McPherson JR, Zhang LH, Rozen S, Sabapathy K.

DNA Repair (Amst). 2016 Oct;46:9-19. doi: 10.1016/j.dnarep.2016.09.001. Epub 2016 Sep 13.

PMID:
27650847
5.

Exome sequencing reveals recurrent REV3L mutations in cisplatin-resistant squamous cell carcinoma of head and neck.

Huang KK, Jang KW, Kim S, Kim HS, Kim SM, Kwon HJ, Kim HR, Yun HJ, Ahn MJ, Park KU, Ramnarayanan K, McPherson JR, Zhang S, Rhee JK, Vettore AL, Das K, Ishimoto T, Kim JH, Koh YW, Kim SH, Choi EC, Teh BT, Rozen SG, Kim TM, Tan P, Cho BC.

Sci Rep. 2016 Jan 21;6:19552. doi: 10.1038/srep19552.

6.

Genomic landscapes of breast fibroepithelial tumors.

Tan J, Ong CK, Lim WK, Ng CC, Thike AA, Ng LM, Rajasegaran V, Myint SS, Nagarajan S, Thangaraju S, Dey S, Nasir ND, Wijaya GC, Lim JQ, Huang D, Li Z, Wong BH, Chan JY, McPherson JR, Cutcutache I, Poore G, Tay ST, Tan WJ, Putti TC, Ahmad BS, Iau P, Chan CW, Tang AP, Yong WS, Madhukumar P, Ho GH, Tan VK, Wong CY, Hartman M, Ong KW, Tan BK, Rozen SG, Tan P, Tan PH, Teh BT.

Nat Genet. 2015 Nov;47(11):1341-5. doi: 10.1038/ng.3409. Epub 2015 Oct 5.

PMID:
26437033
7.

Whole-exome sequencing of breast cancer, malignant peripheral nerve sheath tumor and neurofibroma from a patient with neurofibromatosis type 1.

McPherson JR, Ong CK, Ng CC, Rajasegaran V, Heng HL, Yu WS, Tan BK, Madhukumar P, Teo MC, Ngeow J, Thike AA, Rozen SG, Tan PH, Lee AS, Teh BT, Yap YS.

Cancer Med. 2015 Dec;4(12):1871-8. doi: 10.1002/cam4.551. Epub 2015 Oct 3.

8.

Mutational landscapes of tongue carcinoma reveal recurrent mutations in genes of therapeutic and prognostic relevance.

Vettore AL, Ramnarayanan K, Poore G, Lim K, Ong CK, Huang KK, Leong HS, Chong FT, Lim TK, Lim WK, Cutcutache I, Mcpherson JR, Suzuki Y, Zhang S, Skanthakumar T, Wang W, Tan DS, Cho BC, Teh BT, Rozen S, Tan P, Iyer NG.

Genome Med. 2015 Sep 23;7:98. doi: 10.1186/s13073-015-0219-2.

9.

SETD2 histone modifier loss in aggressive GI stromal tumours.

Huang KK, McPherson JR, Tay ST, Das K, Tan IB, Ng CC, Chia NY, Zhang SL, Myint SS, Hu L, Rajasegaran V, Huang D, Loh JL, Gan A, Sairi AN, Sam XX, Dominguez LT, Lee M, Soo KC, Ooi LL, Ong HS, Chung A, Chow PK, Wong WK, Selvarajan S, Ong CK, Lim KH, Nandi T, Rozen S, Teh BT, Quek R, Tan P.

Gut. 2016 Dec;65(12):1960-1972. doi: 10.1136/gutjnl-2015-309482. Epub 2015 Sep 3.

PMID:
26338826
10.

MSIseq: Software for Assessing Microsatellite Instability from Catalogs of Somatic Mutations.

Huang MN, McPherson JR, Cutcutache I, Teh BT, Tan P, Rozen SG.

Sci Rep. 2015 Aug 26;5:13321. doi: 10.1038/srep13321.

11.

Abundant copy-number loss of CYCLOPS and STOP genes in gastric adenocarcinoma.

Cutcutache I, Wu AY, Suzuki Y, McPherson JR, Lei Z, Deng N, Zhang S, Wong WK, Soo KC, Chan WH, Ooi LL, Welsch R, Tan P, Rozen SG.

Gastric Cancer. 2016 Apr;19(2):453-465. doi: 10.1007/s10120-015-0514-z. Epub 2015 Jul 24.

12.

Mutation signatures implicate aristolochic acid in bladder cancer development.

Poon SL, Huang MN, Choo Y, McPherson JR, Yu W, Heng HL, Gan A, Myint SS, Siew EY, Ler LD, Ng LG, Weng WH, Chuang CK, Yuen JS, Pang ST, Tan P, Teh BT, Rozen SG.

Genome Med. 2015 Apr 28;7(1):38. doi: 10.1186/s13073-015-0161-3. eCollection 2015.

13.

High-depth sequencing of over 750 genes supports linear progression of primary tumors and metastases in most patients with liver-limited metastatic colorectal cancer.

Tan IB, Malik S, Ramnarayanan K, McPherson JR, Ho DL, Suzuki Y, Ng SB, Yan S, Lim KH, Koh D, Hoe CM, Chan CY, Ten R, Goh BK, Chung AY, Tan J, Chan CX, Tay ST, Alexander L, Nagarajan N, Hillmer AM, Tang CL, Chua C, Teh BT, Rozen S, Tan P.

Genome Biol. 2015 Feb 12;16:32. doi: 10.1186/s13059-015-0589-1.

14.

Whole-exome sequencing studies of parathyroid carcinomas reveal novel PRUNE2 mutations, distinctive mutational spectra related to APOBEC-catalyzed DNA mutagenesis and mutational enrichment in kinases associated with cell migration and invasion.

Yu W, McPherson JR, Stevenson M, van Eijk R, Heng HL, Newey P, Gan A, Ruano D, Huang D, Poon SL, Ong CK, van Wezel T, Cavaco B, Rozen SG, Tan P, Teh BT, Thakker RV, Morreau H.

J Clin Endocrinol Metab. 2015 Feb;100(2):E360-4. doi: 10.1210/jc.2014-3238. Epub 2014 Nov 11.

PMID:
25387265
15.

Exome sequencing identifies highly recurrent MED12 somatic mutations in breast fibroadenoma.

Lim WK, Ong CK, Tan J, Thike AA, Ng CC, Rajasegaran V, Myint SS, Nagarajan S, Nasir ND, McPherson JR, Cutcutache I, Poore G, Tay ST, Ooi WS, Tan VK, Hartman M, Ong KW, Tan BK, Rozen SG, Tan PH, Tan P, Teh BT.

Nat Genet. 2014 Aug;46(8):877-80. doi: 10.1038/ng.3037. Epub 2014 Jul 20.

PMID:
25038752
16.

Mutation signatures of carcinogen exposure: genome-wide detection and new opportunities for cancer prevention.

Poon SL, McPherson JR, Tan P, Teh BT, Rozen SG.

Genome Med. 2014 Mar 31;6(3):24. doi: 10.1186/gm541. eCollection 2014. Review.

17.

The NF1 gene revisited - from bench to bedside.

Yap YS, McPherson JR, Ong CK, Rozen SG, Teh BT, Lee AS, Callen DF.

Oncotarget. 2014 Aug 15;5(15):5873-92. Review.

18.

Exome sequencing identifies distinct mutational patterns in liver fluke-related and non-infection-related bile duct cancers.

Chan-On W, Nairismägi ML, Ong CK, Lim WK, Dima S, Pairojkul C, Lim KH, McPherson JR, Cutcutache I, Heng HL, Ooi L, Chung A, Chow P, Cheow PC, Lee SY, Choo SP, Tan IB, Duda D, Nastase A, Myint SS, Wong BH, Gan A, Rajasegaran V, Ng CC, Nagarajan S, Jusakul A, Zhang S, Vohra P, Yu W, Huang D, Sithithaworn P, Yongvanit P, Wongkham S, Khuntikeo N, Bhudhisawasdi V, Popescu I, Rozen SG, Tan P, Teh BT.

Nat Genet. 2013 Dec;45(12):1474-8. doi: 10.1038/ng.2806. Epub 2013 Nov 3.

PMID:
24185513
19.

Genome-wide mutational signatures of aristolochic acid and its application as a screening tool.

Poon SL, Pang ST, McPherson JR, Yu W, Huang KK, Guan P, Weng WH, Siew EY, Liu Y, Heng HL, Chong SC, Gan A, Tay ST, Lim WK, Cutcutache I, Huang D, Ler LD, Nairismägi ML, Lee MH, Chang YH, Yu KJ, Chan-On W, Li BK, Yuan YF, Qian CN, Ng KF, Wu CF, Hsu CL, Bunte RM, Stratton MR, Futreal PA, Sung WK, Chuang CK, Ong CK, Rozen SG, Tan P, Teh BT.

Sci Transl Med. 2013 Aug 7;5(197):197ra101. doi: 10.1126/scitranslmed.3006086.

20.

Exome sequencing of liver fluke-associated cholangiocarcinoma.

Ong CK, Subimerb C, Pairojkul C, Wongkham S, Cutcutache I, Yu W, McPherson JR, Allen GE, Ng CC, Wong BH, Myint SS, Rajasegaran V, Heng HL, Gan A, Zang ZJ, Wu Y, Wu J, Lee MH, Huang D, Ong P, Chan-on W, Cao Y, Qian CN, Lim KH, Ooi A, Dykema K, Furge K, Kukongviriyapan V, Sripa B, Wongkham C, Yongvanit P, Futreal PA, Bhudhisawasdi V, Rozen S, Tan P, Teh BT.

Nat Genet. 2012 May 6;44(6):690-3. doi: 10.1038/ng.2273.

PMID:
22561520
21.

Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes.

Zang ZJ, Cutcutache I, Poon SL, Zhang SL, McPherson JR, Tao J, Rajasegaran V, Heng HL, Deng N, Gan A, Lim KH, Ong CK, Huang D, Chin SY, Tan IB, Ng CC, Yu W, Wu Y, Lee M, Wu J, Poh D, Wan WK, Rha SY, So J, Salto-Tellez M, Yeoh KG, Wong WK, Zhu YJ, Futreal PA, Pang B, Ruan Y, Hillmer AM, Bertrand D, Nagarajan N, Rozen S, Teh BT, Tan P.

Nat Genet. 2012 May;44(5):570-4. doi: 10.1038/ng.2246.

PMID:
22484628
22.

Regulation of TNF-alpha-induced IL-6 production in MG-63 human osteoblast-like cells.

Webb SJ, McPherson JR, Pahan K, Koka S.

J Dent Res. 2002 Jan;81(1):17-22.

PMID:
11820362
23.

Should we change the medical school curriculum?

McPherson JR.

Mayo Clin Proc. 1989 Oct;64(10):1311-4. No abstract available.

PMID:
2687594
24.

Experience with providing research opportunities for medical students.

McPherson JR, Mitchell MM.

J Med Educ. 1984 Nov;59(11 Pt 1):865-8.

PMID:
6492103
25.

D.C. General Hospital: the nurse specialist hypertension clinic.

McPherson JR, Mroczek WJ.

Urban Health. 1979 Mar;8(2):46, 48. No abstract available.

PMID:
10241526
26.

Stature change with aging in black americans.

McPherson JR, Lancaster DR, Carroll JC.

J Gerontol. 1978 Jan;33(1):20-5.

PMID:
618961
27.

Patient and personnel motivation in a geriatric setting.

McPherson JR, Lancaster DR.

Nurs Homes. 1975 Aug-Sep;24(5):15-6. No abstract available.

PMID:
1042761
28.

Jejunal biopsy.

McPherson JR.

Med Clin North Am. 1970 Jul;54(4):851-62. No abstract available.

PMID:
4193250
29.

Malabsorption in rheumatoid arthritis: an unusual complication caused by amyloidosis.

Babb RR, Alarcón-Segovia D, Diessner GR, McPherson JR.

Arthritis Rheum. 1967 Feb;10(1):63-70. No abstract available.

PMID:
6019347
30.

Lupus erythematosus presenting as an acute abdomen.

Dubnow MH, McPherson JR, Bowie EJ.

Minn Med. 1966 Apr;49(4):577-9. No abstract available.

PMID:
5907234
31.

The sulfobromophthalein sodium test: a review.

Babb RR, McPherson JR.

Manit Med Rev. 1966 Feb;46(2):124-6. Review. No abstract available.

PMID:
5323189
32.

Intestinal lesions associated with triparanol. A clinical and experimental study.

McPherson JR, Shorter RG.

Am J Dig Dis. 1965 Dec;10(12):1024-33. No abstract available.

PMID:
5846503
33.

Jejunal biopsy in the diagnosis of malabsorption syndromes.

McPherson JR.

Dis Colon Rectum. 1965 Nov-Dec;8(6):425-30. No abstract available.

PMID:
4158553
34.

THROMBOANGIITIS OBLITERANS AND ARTERIOSCLEROSIS OBLITERANS. CLINICAL AND PROGNOSTIC DIFFERENCES.

MCPHERSON JR, JUERGENS JL, GIFFORD RW Jr.

Ann Intern Med. 1963 Sep;59:288-96. No abstract available.

PMID:
14065946
35.

An acute malabsorption syndrome with reversible mucosal atrophy.

MCPHERSON JR, SUMMERSKILL WH.

Gastroenterology. 1963 Jun;44:900-4. No abstract available.

PMID:
13932262
36.

Effect of soy-flour diet and other agents on excretion of I-131 after use of labeled thyroxine in the rat.

MCPHERSON JR, ALBERT A.

Endocrinology. 1961 Oct;69:856-62. No abstract available.

PMID:
13774172

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