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Items: 32

1.

PIK3CA missense mutations promote glioblastoma pathogenesis, but do not enhance targeted PI3K inhibition.

McNeill RS, Stroobant EE, Smithberger E, Canoutas DA, Butler MK, Shelton AK, Patel SD, Limas JC, Skinner KR, Bash RE, Schmid RS, Miller CR.

PLoS One. 2018 Jul 5;13(7):e0200014. doi: 10.1371/journal.pone.0200014. eCollection 2018.

2.

Combined kinase inhibitors of MEK1/2 and either PI3K or PDGFR are efficacious in intracranial triple-negative breast cancer.

Van Swearingen AED, Sambade MJ, Siegel MB, Sud S, McNeill RS, Bevill SM, Chen X, Bash RE, Mounsey L, Golitz BT, Santos C, Deal A, Parker JS, Rashid N, Miller CR, Johnson GL, Anders CK.

Neuro Oncol. 2017 Oct 19;19(11):1481-1493. doi: 10.1093/neuonc/nox052.

3.

Genomic profiles of low-grade murine gliomas evolve during progression to glioblastoma.

Vitucci M, Irvin DM, McNeill RS, Schmid RS, Simon JM, Dhruv HD, Siegel MB, Werneke AM, Bash RE, Kim S, Berens ME, Miller CR.

Neuro Oncol. 2017 Sep 1;19(9):1237-1247. doi: 10.1093/neuonc/nox050.

4.

Combination therapy with potent PI3K and MAPK inhibitors overcomes adaptive kinome resistance to single agents in preclinical models of glioblastoma.

McNeill RS, Canoutas DA, Stuhlmiller TJ, Dhruv HD, Irvin DM, Bash RE, Angus SP, Herring LE, Simon JM, Skinner KR, Limas JC, Chen X, Schmid RS, Siegel MB, Van Swearingen AED, Hadler MJ, Sulman EP, Sarkaria JN, Anders CK, Graves LM, Berens ME, Johnson GL, Miller CR.

Neuro Oncol. 2017 Oct 19;19(11):1469-1480. doi: 10.1093/neuonc/nox044.

5.

BRAF Mutations Open Doors for N-Ethyl-N-Nitrosourea-Induced Gliomagenesis.

McNeill RS, Irvin DM, Miller CR.

Am J Pathol. 2016 Oct;186(10):2551-4. doi: 10.1016/j.ajpath.2016.07.005. Epub 2016 Aug 18.

6.

Core pathway mutations induce de-differentiation of murine astrocytes into glioblastoma stem cells that are sensitive to radiation but resistant to temozolomide.

Schmid RS, Simon JM, Vitucci M, McNeill RS, Bash RE, Werneke AM, Huey L, White KK, Ewend MG, Wu J, Miller CR.

Neuro Oncol. 2016 Jul;18(7):962-73. doi: 10.1093/neuonc/nov321. Epub 2016 Jan 28.

7.

Intrinsic Astrocyte Heterogeneity Influences Tumor Growth in Glioma Mouse Models.

Irvin DM, McNeill RS, Bash RE, Miller CR.

Brain Pathol. 2017 Jan;27(1):36-50. doi: 10.1111/bpa.12348. Epub 2016 Apr 13.

8.

Transformation of quiescent adult oligodendrocyte precursor cells into malignant glioma through a multistep reactivation process.

Galvao RP, Kasina A, McNeill RS, Harbin JE, Foreman O, Verhaak RG, Nishiyama A, Miller CR, Zong H.

Proc Natl Acad Sci U S A. 2014 Oct 7;111(40):E4214-23. doi: 10.1073/pnas.1414389111. Epub 2014 Sep 22.

9.

Contemporary murine models in preclinical astrocytoma drug development.

McNeill RS, Vitucci M, Wu J, Miller CR.

Neuro Oncol. 2015 Jan;17(1):12-28. doi: 10.1093/neuonc/nou288. Epub 2014 Sep 21. Review.

10.

Modeling astrocytoma pathogenesis in vitro and in vivo using cortical astrocytes or neural stem cells from conditional, genetically engineered mice.

McNeill RS, Schmid RS, Bash RE, Vitucci M, White KK, Werneke AM, Constance BH, Huff B, Miller CR.

J Vis Exp. 2014 Aug 12;(90):e51763. doi: 10.3791/51763.

11.

Cooperativity between MAPK and PI3K signaling activation is required for glioblastoma pathogenesis.

Vitucci M, Karpinich NO, Bash RE, Werneke AM, Schmid RS, White KK, McNeill RS, Huff B, Wang S, Van Dyke T, Miller CR.

Neuro Oncol. 2013 Oct;15(10):1317-29. doi: 10.1093/neuonc/not084. Epub 2013 Jun 27.

12.

The formation and functional consequences of heterogeneous mitochondrial distributions in skeletal muscle.

Pathi B, Kinsey ST, Howdeshell ME, Priester C, McNeill RS, Locke BR.

J Exp Biol. 2012 Jun 1;215(Pt 11):1871-83. doi: 10.1242/jeb.067207.

13.

Chronic bronchitis--measurements and observations over 10 years.

Johnston RN, McNeill RS, Smith DH, Legge JS, Fletcher F.

Thorax. 1976 Feb;31(1):25-29.

14.

Five-year winter chemoprophylaxis for chronic bronchitis.

Johnston RN, McNeill RS, Smith DH, Dempster MB, Nairn JR, Purvis MS, Watson JM, Ward FG.

Br Med J. 1969 Nov 1;4(5678):265-9.

15.

The nature of the adrenergic receptors in isolated human bronchi.

Guirgis HM, McNeill RS.

Thorax. 1969 Sep;24(5):613-5. No abstract available.

16.

Disodium cromoglycate in exercise-induced asthma.

Ward FG, Gomes S, McNeill RS.

Br Med J. 1969 Jul 19;3(5663):176-7. No abstract available.

17.

Exercise-induced asthma.

McNeill RS, Nairn JR, Millar JS, Ingram CG.

Lancet. 1968 Sep 21;2(7569):678. No abstract available.

PMID:
4175506
18.

A comparison of the effect on airway resistance of a new beta blocking drug, ICI.50,172 and propranolol.

Macdonald AG, McNeill RS.

Br J Anaesth. 1968 Jul;40(7):508-10. No abstract available.

19.

The effect of propranolol on airway resistance.

Macdonald AG, Ingram CG, McNeill RS.

Br J Anaesth. 1967 Dec;39(12):919-26. No abstract available.

20.

Effect of propranolol on ventilatory function.

McNeill RS, Ingram CG.

Am J Cardiol. 1966 Sep;18(3):473-5. No abstract available.

PMID:
5922891
21.

Oxygen therapy in the home.

McNeill RS, Watson JM.

Br Med J. 1966 Feb 5;1(5483):331-3. No abstract available.

22.

Exercise-induced asthma.

McNeill RS, Nairn JR, Millar JS, Ingram CG.

Q J Med. 1966 Jan;35(137):55-67. No abstract available.

PMID:
4380323
23.

COLD AIR AND VENTILATORY FUNCTION.

MILLAR JS, NAIR N Jr, UNKLES RD, MCNEILL RS.

Br J Dis Chest. 1965 Jan;59:23-7. No abstract available.

PMID:
14252096
24.

EFFECT OF A BETA-ADRENERGIC-BLOCKING AGENT, PROPRANOLOL, ON ASTHMATICS.

MCNEILL RS.

Lancet. 1964 Nov 21;2(7369):1101-2. No abstract available.

PMID:
14207902
25.

Adaptation of the Wright peak flow meter to measure inspiratory flow.

NAIRN JR, McNEILL RS.

Br Med J. 1963 May 18;1(5341):1321-23. No abstract available.

26.

The effect of anemia on the alveolar-capillary exchange of carbon monoxide in man.

RANKIN J, McNEILL RS, FORSTER RE.

J Clin Invest. 1961 Jul;40:1323-30. No abstract available.

27.

Hydrocortisone by inhalation. Effects on lung function in bronchial asthma.

LANGLANDS JH, MCNEILL RS.

Lancet. 1960 Aug 20;2(7147):404-6. No abstract available.

PMID:
14413989
28.

Influence of increased alveolar carbon dioxide tension on pulmonary diffusing capacity for CO in man.

RANKIN J, McNEILL RS, FORSTER RE.

J Appl Physiol. 1960 Jul;15:543-9. No abstract available.

PMID:
14436188
29.

A clinical and spirometric assessment of airway resistance in rheumatic heart disease.

McNEILL RS, McKENZIE JM.

Scott Med J. 1958 Oct;3(10):417-21. No abstract available.

PMID:
13592322
30.

The diffusing capacity of the pulmonary membrane and the pulmonary capillary blood volume in cardiopulmonary disease.

McNEILL RS, RANKIN J, FORSTER RF.

Clin Sci. 1958 Aug;17(3):465-82. No abstract available.

PMID:
13585656
31.

Hand-Schüller-Christian disease; report of a case with unusual lung changes.

MCNEILL RS, CAMERON HM.

Thorax. 1955 Dec;10(4):314-20. No abstract available.

32.

An assessment of the value of breathing exercises in chronic bronchitis and asthma.

MCNEILL RS, MCKENZIE JM.

Thorax. 1955 Sep;10(3):250-2. No abstract available.

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