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Localization of YAP activity in developing skeletal rudiments is responsive to mechanical stimulation.

Shea CA, Rolfe RA, McNeill H, Murphy P.

Dev Dyn. 2019 Nov 20. doi: 10.1002/dvdy.137. [Epub ahead of print]


Fat/Dachsous family cadherins in cell and tissue organisation.

Fulford AD, McNeill H.

Curr Opin Cell Biol. 2019 Nov 15;62:96-103. doi: 10.1016/ [Epub ahead of print] Review.


Electrocardiographic recognition of life-threatening hyperkalaemia: the hyperkalaemic Brugada sign.

McNeill H, Isles C.

JRSM Open. 2019 Sep 2;10(9):2054270419834243. doi: 10.1177/2054270419834243. eCollection 2019 Sep.


Position effects on promoter activity in Escherichia coli and their consequences for antibiotic-resistance determinants.

Cooke K, Browning DF, Lee DJ, Blair JMA, McNeill HE, Huber D, Busby SJW, Bryant JA.

Biochem Soc Trans. 2019 Jun 28;47(3):839-845. doi: 10.1042/BST20180503. Epub 2019 Jun 12. Review.


Four-jointed knock-out delays renal failure in an ADPKD model with kidney injury.

Formica C, Happé H, Veraar KA, Vortkamp A, Scharpfenecker M, McNeill H, Peters DJ.

J Pathol. 2019 Sep;249(1):114-125. doi: 10.1002/path.5286. Epub 2019 Jun 17.


Homozygous frameshift mutations in FAT1 cause a syndrome characterized by colobomatous-microphthalmia, ptosis, nephropathy and syndactyly.

Lahrouchi N, George A, Ratbi I, Schneider R, Elalaoui SC, Moosa S, Bharti S, Sharma R, Abu-Asab M, Onojafe F, Adadi N, Lodder EM, Laarabi FZ, Lamsyah Y, Elorch H, Chebbar I, Postma AV, Lougaris V, Plebani A, Altmueller J, Kyrieleis H, Meiner V, McNeill H, Bharti K, Lyonnet S, Wollnik B, Henrion-Caude A, Berraho A, Hildebrandt F, Bezzina CR, Brooks BP, Sefiani A.

Nat Commun. 2019 Mar 12;10(1):1180. doi: 10.1038/s41467-019-08547-w.


Fat regulates expression of four-jointed reporters in vivo through a 20 bp element independently of the Hippo pathway.

Arbouzova NI, Fulford AD, Zhang H, McNeill H.

Dev Biol. 2019 Jun 1;450(1):23-33. doi: 10.1016/j.ydbio.2019.03.004. Epub 2019 Mar 9.


FAT4 Fine-Tunes Kidney Development by Regulating RET Signaling.

Zhang H, Bagherie-Lachidan M, Badouel C, Enderle L, Peidis P, Bremner R, Kuure S, Jain S, McNeill H.

Dev Cell. 2019 Mar 25;48(6):780-792.e4. doi: 10.1016/j.devcel.2019.02.004. Epub 2019 Mar 7.


Mechanical stability of the cell nucleus - roles played by the cytoskeleton in nuclear deformation and strain recovery.

Wang X, Liu H, Zhu M, Cao C, Xu Z, Tsatskis Y, Lau K, Kuok C, Filleter T, McNeill H, Simmons CA, Hopyan S, Sun Y.

J Cell Sci. 2018 Jul 4;131(13). pii: jcs209627. doi: 10.1242/jcs.209627.


Atypical Cadherin Dachsous1b Interacts with Ttc28 and Aurora B to Control Microtubule Dynamics in Embryonic Cleavages.

Chen J, Castelvecchi GD, Li-Villarreal N, Raught B, Krezel AM, McNeill H, Solnica-Krezel L.

Dev Cell. 2018 May 7;45(3):376-391.e5. doi: 10.1016/j.devcel.2018.04.009.


Sox11 gene disruption causes congenital anomalies of the kidney and urinary tract (CAKUT).

Neirijnck Y, Reginensi A, Renkema KY, Massa F, Kozlov VM, Dhib H, Bongers EMHF, Feitz WF, van Eerde AM, Lefebvre V, Knoers NVAM, Tabatabaei M, Schulz H, McNeill H, Schaefer F, Wegner M, Sock E, Schedl A.

Kidney Int. 2018 May;93(5):1142-1153. doi: 10.1016/j.kint.2017.11.026. Epub 2018 Feb 17.


Reciprocal Spatiotemporally Controlled Apoptosis Regulates Wolffian Duct Cloaca Fusion.

Hoshi M, Reginensi A, Joens MS, Fitzpatrick JAJ, McNeill H, Jain S.

J Am Soc Nephrol. 2018 Mar;29(3):775-783. doi: 10.1681/ASN.2017040380. Epub 2018 Jan 11.


General Practitioner (GP) trainees' experience of a '1-h protected supervision model' given during psychiatry placements in the United Kingdom.

Thomas G, McNeill H.

Educ Prim Care. 2018 May;29(3):174-177. doi: 10.1080/14739879.2017.1416959. Epub 2018 Jan 5.


Big roles for Fat cadherins.

Blair S, McNeill H.

Curr Opin Cell Biol. 2018 Apr;51:73-80. doi: 10.1016/ Epub 2017 Dec 16. Review.


Editorial overview: Cell dynamics: Dynamic cell decision making.

Piddini E, McNeill H.

Curr Opin Cell Biol. 2017 Oct;48:iv-vi. doi: 10.1016/ Epub 2017 Aug 10. No abstract available.


Atrophin controls developmental signaling pathways via interactions with Trithorax-like.

Yeung K, Boija A, Karlsson E, Holmqvist PH, Tsatskis Y, Nisoli I, Yap D, Lorzadeh A, Moksa M, Hirst M, Aparicio S, Fanto M, Stenberg P, Mannervik M, McNeill H.

Elife. 2017 Mar 22;6. pii: e23084. doi: 10.7554/eLife.23084.


Amotl1 mediates sequestration of the Hippo effector Yap1 downstream of Fat4 to restrict heart growth.

Ragni CV, Diguet N, Le Garrec JF, Novotova M, Resende TP, Pop S, Charon N, Guillemot L, Kitasato L, Badouel C, Dufour A, Olivo-Marin JC, Trouvé A, McNeill H, Meilhac SM.

Nat Commun. 2017 Feb 27;8:14582. doi: 10.1038/ncomms14582.


DLG5 connects cell polarity and Hippo signaling protein networks by linking PAR-1 with MST1/2.

Kwan J, Sczaniecka A, Heidary Arash E, Nguyen L, Chen CC, Ratkovic S, Klezovitch O, Attisano L, McNeill H, Emili A, Vasioukhin V.

Genes Dev. 2016 Dec 15;30(24):2696-2709. doi: 10.1101/gad.284539.116.


The Enright phenomenon. Stereoscopic distortion of perceived driving speed induced by monocular pupil dilation.

Carkeet A, Wood JM, McNeill KM, McNeill HJ, James JA, Holder LS.

J Optom. 2017 Oct - Dec;10(4):233-241. doi: 10.1016/j.optom.2016.08.001. Epub 2016 Nov 17.


Drosophila insulin release is triggered by adipose Stunted ligand to brain Methuselah receptor.

Delanoue R, Meschi E, Agrawal N, Mauri A, Tsatskis Y, McNeill H, Léopold P.

Science. 2016 Sep 30;353(6307):1553-1556.


Lats1/2 Regulate Yap/Taz to Control Nephron Progenitor Epithelialization and Inhibit Myofibroblast Formation.

McNeill H, Reginensi A.

J Am Soc Nephrol. 2017 Mar;28(3):852-861. doi: 10.1681/ASN.2016060611. Epub 2016 Sep 19.


A critical role for NF2 and the Hippo pathway in branching morphogenesis.

Reginensi A, Enderle L, Gregorieff A, Johnson RL, Wrana JL, McNeill H.

Nat Commun. 2016 Aug 2;7:12309. doi: 10.1038/ncomms12309.


The Rho Guanine Nucleotide Exchange Factor DRhoGEF2 Is a Genetic Modifier of the PI3K Pathway in Drosophila.

Chang YJ, Zhou L, Binari R, Manoukian A, Mak T, McNeill H, Stambolic V.

PLoS One. 2016 Mar 25;11(3):e0152259. doi: 10.1371/journal.pone.0152259. eCollection 2016.


Regulation of cell polarity determinants by the Retinoblastoma tumor suppressor protein.

Payankaulam S, Yeung K, McNeill H, Henry RW, Arnosti DN.

Sci Rep. 2016 Mar 14;6:22879. doi: 10.1038/srep22879.


FAT1 mutations cause a glomerulotubular nephropathy.

Gee HY, Sadowski CE, Aggarwal PK, Porath JD, Yakulov TA, Schueler M, Lovric S, Ashraf S, Braun DA, Halbritter J, Fang H, Airik R, Vega-Warner V, Cho KJ, Chan TA, Morris LG, ffrench-Constant C, Allen N, McNeill H, Büscher R, Kyrieleis H, Wallot M, Gaspert A, Kistler T, Milford DV, Saleem MA, Keng WT, Alexander SI, Valentini RP, Licht C, Teh JC, Bogdanovic R, Koziell A, Bierzynska A, Soliman NA, Otto EA, Lifton RP, Holzman LB, Sibinga NE, Walz G, Tufro A, Hildebrandt F.

Nat Commun. 2016 Feb 24;7:10822. doi: 10.1038/ncomms10822.


SAPCD2 Controls Spindle Orientation and Asymmetric Divisions by Negatively Regulating the Gαi-LGN-NuMA Ternary Complex.

Chiu CWN, Monat C, Robitaille M, Lacomme M, Daulat AM, Macleod G, McNeill H, Cayouette M, Angers S.

Dev Cell. 2016 Jan 11;36(1):50-62. doi: 10.1016/j.devcel.2015.12.016.


Yap and Taz are required for Ret-dependent urinary tract morphogenesis.

Reginensi A, Hoshi M, Boualia SK, Bouchard M, Jain S, McNeill H.

Development. 2015 Aug 1;142(15):2696-703. doi: 10.1242/dev.122044.


Fat1 interacts with Fat4 to regulate neural tube closure, neural progenitor proliferation and apical constriction during mouse brain development.

Badouel C, Zander MA, Liscio N, Bagherie-Lachidan M, Sopko R, Coyaud E, Raught B, Miller FD, McNeill H.

Development. 2015 Aug 15;142(16):2781-91. doi: 10.1242/dev.123539. Epub 2015 Jul 24.


Stromal Fat4 acts non-autonomously with Dchs1/2 to restrict the nephron progenitor pool.

Bagherie-Lachidan M, Reginensi A, Pan Q, Zaveri HP, Scott DA, Blencowe BJ, Helmbacher F, McNeill H.

Development. 2015 Aug 1;142(15):2564-73. doi: 10.1242/dev.122648. Epub 2015 Jun 26.


Atypical Cadherin Fat1 Is Required for Lens Epithelial Cell Polarity and Proliferation but Not for Fiber Differentiation.

Sugiyama Y, Shelley EJ, Badouel C, McNeill H, McAvoy JW.

Invest Ophthalmol Vis Sci. 2015 Jun;56(6):4099-107. doi: 10.1167/iovs.15-17008.


Podocyte-Specific Deletion of Yes-Associated Protein Causes FSGS and Progressive Renal Failure.

Schwartzman M, Reginensi A, Wong JS, Basgen JM, Meliambro K, Nicholas SB, D'Agati V, McNeill H, Campbell KN.

J Am Soc Nephrol. 2016 Jan;27(1):216-26. doi: 10.1681/ASN.2014090916. Epub 2015 May 26.


The atypical cadherin fat directly regulates mitochondrial function and metabolic state.

Sing A, Tsatskis Y, Fabian L, Hester I, Rosenfeld R, Serricchio M, Yau N, Bietenhader M, Shanbhag R, Jurisicova A, Brill JA, McQuibban GA, McNeill H.

Cell. 2014 Sep 11;158(6):1293-1308. doi: 10.1016/j.cell.2014.07.036.


Unkempt is negatively regulated by mTOR and uncouples neuronal differentiation from growth control.

Avet-Rochex A, Carvajal N, Christoforou CP, Yeung K, Maierbrugger KT, Hobbs C, Lalli G, Cagin U, Plachot C, McNeill H, Bateman JM.

PLoS Genet. 2014 Sep 11;10(9):e1004624. doi: 10.1371/journal.pgen.1004624. eCollection 2014 Sep.


Regulation of neuronal migration by Dchs1-Fat4 planar cell polarity.

Zakaria S, Mao Y, Kuta A, de Sousa CF, Gaufo GO, McNeill H, Hindges R, Guthrie S, Irvine KD, Francis-West PH.

Curr Biol. 2014 Jul 21;24(14):1620-1627. doi: 10.1016/j.cub.2014.05.067. Epub 2014 Jul 3.


In vivo interaction proteomics reveal a novel p38 mitogen-activated protein kinase/Rack1 pathway regulating proteostasis in Drosophila muscle.

Belozerov VE, Ratkovic S, McNeill H, Hilliker AJ, McDermott JC.

Mol Cell Biol. 2014 Feb;34(3):474-84. doi: 10.1128/MCB.00824-13. Epub 2013 Nov 25.


Hippo gains weight: added insights and complexity to pathway control.

Enderle L, McNeill H.

Sci Signal. 2013 Oct 8;6(296):re7. doi: 10.1126/scisignal.2004208.


Mutations in genes encoding the cadherin receptor-ligand pair DCHS1 and FAT4 disrupt cerebral cortical development.

Cappello S, Gray MJ, Badouel C, Lange S, Einsiedler M, Srour M, Chitayat D, Hamdan FF, Jenkins ZA, Morgan T, Preitner N, Uster T, Thomas J, Shannon P, Morrison V, Di Donato N, Van Maldergem L, Neuhann T, Newbury-Ecob R, Swinkells M, Terhal P, Wilson LC, Zwijnenburg PJ, Sutherland-Smith AJ, Black MA, Markie D, Michaud JL, Simpson MA, Mansour S, McNeill H, Götz M, Robertson SP.

Nat Genet. 2013 Nov;45(11):1300-8. doi: 10.1038/ng.2765. Epub 2013 Sep 22.


Regulation of long-range planar cell polarity by Fat-Dachsous signaling.

Sharma P, McNeill H.

Development. 2013 Sep;140(18):3869-81. doi: 10.1242/dev.094730. Epub 2013 Aug 14.


Molecular parameters of siRNA--cell penetrating peptide nanocomplexes for efficient cellular delivery.

van Asbeck AH, Beyerle A, McNeill H, Bovee-Geurts PH, Lindberg S, Verdurmen WP, Hällbrink M, Langel U, Heidenreich O, Brock R.

ACS Nano. 2013 May 28;7(5):3797-807. doi: 10.1021/nn305754c. Epub 2013 Apr 30.


An evolutionary shift in the regulation of the Hippo pathway between mice and flies.

Bossuyt W, Chen CL, Chen Q, Sudol M, McNeill H, Pan D, Kopp A, Halder G.

Oncogene. 2014 Mar 6;33(10):1218-28. doi: 10.1038/onc.2013.82. Epub 2013 Apr 8.


Yap- and Cdc42-dependent nephrogenesis and morphogenesis during mouse kidney development.

Reginensi A, Scott RP, Gregorieff A, Bagherie-Lachidan M, Chung C, Lim DS, Pawson T, Wrana J, McNeill H.

PLoS Genet. 2013 Mar;9(3):e1003380. doi: 10.1371/journal.pgen.1003380. Epub 2013 Mar 21.


Organizer formation in Hydra is disrupted by thalidomide treatment.

Brooun M, Manoukian A, Shimizu H, Bode HR, McNeill H.

Dev Biol. 2013 Jun 1;378(1):51-63. doi: 10.1016/j.ydbio.2013.03.013. Epub 2013 Mar 24.


Fat and Dachsous cadherins.

Sharma P, McNeill H.

Prog Mol Biol Transl Sci. 2013;116:215-35. doi: 10.1016/B978-0-12-394311-8.00010-8. Review.


Characterisation of a Tip60 specific inhibitor, NU9056, in prostate cancer.

Coffey K, Blackburn TJ, Cook S, Golding BT, Griffin RJ, Hardcastle IR, Hewitt L, Huberman K, McNeill HV, Newell DR, Roche C, Ryan-Munden CA, Watson A, Robson CN.

PLoS One. 2012;7(10):e45539. doi: 10.1371/journal.pone.0045539. Epub 2012 Oct 8.


Focussing both eyes on health outcomes: revisiting cataract surgery.

Davis JC, McNeill H, Wasdell M, Chunick S, Bryan S.

BMC Geriatr. 2012 Sep 3;12:50. doi: 10.1186/1471-2318-12-50.


Concerted control of gliogenesis by InR/TOR and FGF signalling in the Drosophila post-embryonic brain.

Avet-Rochex A, Kaul AK, Gatt AP, McNeill H, Bateman JM.

Development. 2012 Aug;139(15):2763-72. doi: 10.1242/dev.074179. Epub 2012 Jun 28.


Functional interactions between Fat family cadherins in tissue morphogenesis and planar polarity.

Saburi S, Hester I, Goodrich L, McNeill H.

Development. 2012 May;139(10):1806-20. doi: 10.1242/dev.077461.


Depletion of RUNX1/ETO in t(8;21) AML cells leads to genome-wide changes in chromatin structure and transcription factor binding.

Ptasinska A, Assi SA, Mannari D, James SR, Williamson D, Dunne J, Hoogenkamp M, Wu M, Care M, McNeill H, Cauchy P, Cullen M, Tooze RM, Tenen DG, Young BD, Cockerill PN, Westhead DR, Heidenreich O, Bonifer C.

Leukemia. 2012 Aug;26(8):1829-41. doi: 10.1038/leu.2012.49. Epub 2012 Feb 20.


Mink1 regulates β-catenin-independent Wnt signaling via Prickle phosphorylation.

Daulat AM, Luu O, Sing A, Zhang L, Wrana JL, McNeill H, Winklbauer R, Angers S.

Mol Cell Biol. 2012 Jan;32(1):173-85. doi: 10.1128/MCB.06320-11. Epub 2011 Oct 28.


The Hippo tumor suppressor pathway: a report on 'the Second Workshop On The Hippo tumor suppressor pathway'.

McNeill H, Sudol M, Halder G, Strano S, Blandino G, Shaul Y.

Cell Death Differ. 2011 Aug;18(8):1388-90. doi: 10.1038/cdd.2011.61. Epub 2011 May 13. No abstract available.

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