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Items: 50


Predictors of Hand Contracture in Early Systemic Sclerosis and the Effect on Function: A Prospective Study of the GENISOS Cohort.

Buni M, Joseph J, Pedroza C, Theodore S, Nair D, McNearney TA, Draeger HT, Reveille JD, Assassi S, Mayes MD.

J Rheumatol. 2019 Dec;46(12):1597-1604. doi: 10.3899/jrheum.180093. Epub 2019 Feb 1.


Applications of Bayesian statistical methodology to clinical trial design: A case study of a phase 2 trial with an interim futility assessment in patients with knee osteoarthritis.

Smith CL, Jin Y, Raddad E, McNearney TA, Ni X, Monteith D, Brown R, Deeg MA, Schnitzer T.

Pharm Stat. 2019 Jan;18(1):39-53. doi: 10.1002/pst.1906. Epub 2018 Oct 15.


CGRP blockade by galcanezumab was not associated with reductions in signs and symptoms of knee osteoarthritis in a randomized clinical trial.

Jin Y, Smith C, Monteith D, Brown R, Camporeale A, McNearney TA, Deeg MA, Raddad E, Xiao N, de la Peña A, Kivitz AJ, Schnitzer TJ.

Osteoarthritis Cartilage. 2018 Dec;26(12):1609-1618. doi: 10.1016/j.joca.2018.08.019. Epub 2018 Sep 18.


Dose-dependent acute liver injury with hypersensitivity features in humans due to a novel microsomal prostaglandin E synthase 1 inhibitor.

Jin Y, Regev A, Kam J, Phipps K, Smith C, Henck J, Campanale K, Hu L, Hall DG, Yang XY, Nakano M, McNearney TA, Uetrecht J, Landschulz W.

Br J Clin Pharmacol. 2018 Jan;84(1):179-188. doi: 10.1111/bcp.13423. Epub 2017 Oct 8.


LY3127760, a Selective Prostaglandin E4 (EP4) Receptor Antagonist, and Celecoxib: A Comparison of Pharmacological Profiles.

Jin Y, Smith C, Hu L, Coutant DE, Whitehurst K, Phipps K, McNearney TA, Yang X, Ackermann B, Pottanat T, Landschulz W.

Clin Transl Sci. 2018 Jan;11(1):46-53. doi: 10.1111/cts.12497. Epub 2017 Aug 30.


Direct in vivo evidence of activated macrophages in human osteoarthritis.

Kraus VB, McDaniel G, Huebner JL, Stabler TV, Pieper CF, Shipes SW, Petry NA, Low PS, Shen J, McNearney TA, Mitchell P.

Osteoarthritis Cartilage. 2016 Sep;24(9):1613-21. doi: 10.1016/j.joca.2016.04.010. Epub 2016 Apr 12.


Pharmacodynamic comparison of LY3023703, a novel microsomal prostaglandin e synthase 1 inhibitor, with celecoxib.

Jin Y, Smith CL, Hu L, Campanale KM, Stoltz R, Huffman LG Jr, McNearney TA, Yang XY, Ackermann BL, Dean R, Regev A, Landschulz W.

Clin Pharmacol Ther. 2016 Mar;99(3):274-84. doi: 10.1002/cpt.260. Epub 2015 Nov 25.


Cannabinoid receptor 2 agonist attenuates pain related behavior in rats with chronic alcohol/high fat diet induced pancreatitis.

Zhang L, Kline RH 4th, McNearney TA, Johnson MP, Westlund KN.

Mol Pain. 2014 Nov 17;10:66. doi: 10.1186/1744-8069-10-66.


Gain and loss of function of P2X7 receptors: mechanisms, pharmacology and relevance to diabetic neuropathic pain.

Ursu D, Ebert P, Langron E, Ruble C, Munsie L, Zou W, Fijal B, Qian YW, McNearney TA, Mogg A, Grubisha O, Merchant K, Sher E.

Mol Pain. 2014 Jun 16;10:37. doi: 10.1186/1744-8069-10-37.


Acupuncture-based modalities: novel alternative approaches in the treatment of gastrointestinal dysmotility in patients with systemic sclerosis.

Sallam HS, McNearney TA, Chen JD.

Explore (NY). 2014 Jan-Feb;10(1):44-52. doi: 10.1016/j.explore.2013.10.001. Epub 2013 Oct 17. Review.


Value of isolated IgA anti-β2 -glycoprotein I positivity in the diagnosis of the antiphospholipid syndrome.

Murthy V, Willis R, Romay-Penabad Z, Ruiz-Limón P, Martínez-Martínez LA, Jatwani S, Jajoria P, Seif A, Alarcón GS, Papalardo E, Liu J, Vilá LM, McGwin G Jr, McNearney TA, Maganti R, Sunkureddi P, Parekh T, Tarantino M, Akhter E, Fang H, Gonzalez EB, Binder WR, Norman GL, Shums Z, Teodorescu M, Reveille JD, Petri M, Pierangeli SS.

Arthritis Rheum. 2013 Dec;65(12):3186-93. doi: 10.1002/art.38131.


Excitatory amino acids display compartmental disparity between plasma and synovial fluid in clinical arthropathies.

McNearney TA, Westlund KN.

Int J Clin Exp Pathol. 2013;6(3):492-7. Epub 2013 Feb 15.


Measuring illness behavior in patients with systemic sclerosis.

Merz EL, Malcarne VL, Roesch SC, Sharif R, Harper BE, Draeger HT, Gonzalez EB, Nair DK, McNearney TA, Assassi S, Mayes MD.

Arthritis Care Res (Hoboken). 2013 Apr;65(4):585-93. doi: 10.1002/acr.21874.


Predictors of fatigue severity in early systemic sclerosis: a prospective longitudinal study of the GENISOS cohort.

Assassi S, Leyva AL, Mayes MD, Sharif R, Nair DK, Fischbach M, Nguyen N, Reveille JD, Gonzalez EB, McNearney TA; GENISOS Study Group.

PLoS One. 2011;6(10):e26061. doi: 10.1371/journal.pone.0026061. Epub 2011 Oct 14.


Anorectal motility and sensation abnormalities and its correlation with anorectal symptoms in patients with systemic sclerosis: a preliminary study.

Sallam HS, McNearney TA, Chen JZ.

ISRN Gastroenterol. 2011;2011:402583. doi: 10.5402/2011/402583. Epub 2011 Jun 6.


Anti-fibrillarin antibody in African American patients with systemic sclerosis: immunogenetics, clinical features, and survival analysis.

Sharif R, Fritzler MJ, Mayes MD, Gonzalez EB, McNearney TA, Draeger H, Baron M; Canadian Scleroderma Research Group, Furst DE, Khanna DK, del Junco DJ, Molitor JA, Schiopu E, Phillips K, Seibold JR, Silver RM, Simms RW; GENISOS Study Group, Perry M, Rojo C, Charles J, Zhou X, Agarwal SK, Reveille JD, Assassi S, Arnett FC.

J Rheumatol. 2011 Aug;38(8):1622-30. doi: 10.3899/jrheum.110071. Epub 2011 May 15.


Determinants of work disability in patients with systemic sclerosis: a longitudinal study of the GENISOS cohort.

Sharif R, Mayes MD, Nicassio PM, Gonzalez EB, Draeger H, McNearney TA, Estrada-Y-Martin RM, Nair DK, Reveille JD, Arnett FC, Assassi S; GENISOS Study Group.

Semin Arthritis Rheum. 2011 Aug;41(1):38-47. doi: 10.1016/j.semarthrit.2011.01.002. Epub 2011 Mar 22.


Impaired postprandial releases/syntheses of ghrelin and PYY(3-36) and blunted responses to exogenous ghrelin and PYY(3-36) in a rodent model of diet-induced obesity.

Xu J, McNearney TA, Chen JD.

J Gastroenterol Hepatol. 2011 Apr;26(4):700-5. doi: 10.1111/j.1440-1746.2010.06563.x.


Predictors of interstitial lung disease in early systemic sclerosis: a prospective longitudinal study of the GENISOS cohort.

Assassi S, Sharif R, Lasky RE, McNearney TA, Estrada-Y-Martin RM, Draeger H, Nair DK, Fritzler MJ, Reveille JD, Arnett FC, Mayes MD; GENISOS Study Group.

Arthritis Res Ther. 2010;12(5):R166. doi: 10.1186/ar3125. Epub 2010 Sep 2.


Plasma endogenous enkephalin levels in early systemic sclerosis: clinical and laboratory associations.

McNearney TA, Sluka KA, Ahn C, Reveille JD, Fischbach M, Mayes MD.

Clin Exp Rheumatol. 2010 Mar-Apr;28(2 Suppl 58):S7-11. Epub 2010 Jun 10.


Impact of central and peripheral TRPV1 and ROS levels on proinflammatory mediators and nociceptive behavior.

Westlund KN, Kochukov MY, Lu Y, McNearney TA.

Mol Pain. 2010 Aug 6;6:46. doi: 10.1186/1744-8069-6-46.


Systemic sclerosis and lupus: points in an interferon-mediated continuum.

Assassi S, Mayes MD, Arnett FC, Gourh P, Agarwal SK, McNearney TA, Chaussabel D, Oommen N, Fischbach M, Shah KR, Charles J, Pascual V, Reveille JD, Tan FK.

Arthritis Rheum. 2010 Feb;62(2):589-98. doi: 10.1002/art.27224.


A peripheral neuroimmune link: glutamate agonists upregulate NMDA NR1 receptor mRNA and protein, vimentin, TNF-alpha, and RANTES in cultured human synoviocytes.

McNearney TA, Ma Y, Chen Y, Taglialatela G, Yin H, Zhang WR, Westlund KN.

Am J Physiol Regul Integr Comp Physiol. 2010 Mar;298(3):R584-98. doi: 10.1152/ajpregu.00452.2009. Epub 2009 Dec 9.


Perceived functioning has ethnic-specific associations in systemic sclerosis: another dimension of personalized medicine.

McNearney TA, Hunnicutt SE, Fischbach M, Friedman AW, Aguilar M, Ahn CW, Reveille JD, Lisse JR, Baethge BA, Goel N, Mayes MD; GENISOS Study Group.

J Rheumatol. 2009 Dec;36(12):2724-32. doi: 10.3899/jrheum.090295. Epub 2009 Nov 16.


Clinical and genetic factors predictive of mortality in early systemic sclerosis.

Assassi S, Del Junco D, Sutter K, McNearney TA, Reveille JD, Karnavas A, Gourh P, Estrada-Y-Martin RM, Fischbach M, Arnett FC, Mayes MD.

Arthritis Rheum. 2009 Oct 15;61(10):1403-11. doi: 10.1002/art.24734.


Tumor necrosis factor-alpha (TNF-alpha) enhances functional thermal and chemical responses of TRP cation channels in human synoviocytes.

Kochukov MY, McNearney TA, Yin H, Zhang L, Ma F, Ponomareva L, Abshire S, Westlund KN.

Mol Pain. 2009 Aug 20;5:49. doi: 10.1186/1744-8069-5-49.


Gastric slow waves, gastrointestinal symptoms and peptides in systemic sclerosis patients.

McNearney TA, Sallam HS, Hunnicutt SE, Doshi D, Wollaston DE, Mayes MD, Chen JD.

Neurogastroenterol Motil. 2009 Dec;21(12):1269-e120. doi: 10.1111/j.1365-2982.2009.01350.x. Epub 2009 Jun 30.


Complementary and alternative medicine use was associated with higher perceived physical and mental functioning in early systemic sclerosis.

Hunnicutt SE, Grady J, McNearney TA.

Explore (NY). 2008 Jul-Aug;4(4):259-63. doi: 10.1016/j.explore.2008.04.004.


Functional outcome after stroke in patients with rheumatoid arthritis and systemic lupus erythematosus.

Nguyen-Oghalai TU, Wu H, McNearney TA, Granger CV, Ottenbacher KJ.

Arthritis Rheum. 2008 Jul 15;59(7):984-8. doi: 10.1002/art.23816.


What factors relate to job satisfaction among rheumatologists?

McNearney TA, Hunnicutt SE, Maganti R, Rice J.

J Clin Rheumatol. 2008 Jun;14(3):133-7. doi: 10.1097/RHU.0b013e318177274d.


Joint capsule treatment with enkephalin-encoding HSV-1 recombinant vector reduces inflammatory damage and behavioural sequelae in rat CFA monoarthritis.

Lu Y, McNearney TA, Wilson SP, Yeomans DC, Westlund KN.

Eur J Neurosci. 2008 Mar;27(5):1153-65. doi: 10.1111/j.1460-9568.2008.06076.x.


Enkephalin-encoding herpes simplex virus-1 decreases inflammation and hotplate sensitivity in a chronic pancreatitis model.

Yang H, McNearney TA, Chu R, Lu Y, Ren Y, Yeomans DC, Wilson SP, Westlund KN.

Mol Pain. 2008 Feb 28;4:8. doi: 10.1186/1744-8069-4-8.


Unusual Occurrence of renal cell carcinoma (RCC) diagnosed in 2 young Hispanic patients with diffuse systemic sclerosis (dSSc).

Eisenberg ME, Sunkureddi PR, Baethge BA, Gonzalez EB, McNearney TA.

J Clin Rheumatol. 2007 Dec;13(6):363-4. doi: 10.1097/RHU.0b013e31815c39c3. No abstract available.


Factors that impact decision making among rheumatologists in the initiation of treatment for hypertension in rheumatoid arthritis.

Nguyen-Oghalai TU, Hunnicutt SE, Smith ST, Maganti R, McNearney TA.

J Clin Rheumatol. 2007 Dec;13(6):307-12. doi: 10.1097/RHU.0b013e318156bcc2.


Development of a preliminary scleroderma gastrointestinal tract 1.0 quality of life instrument.

Khanna D, Hays RD, Park GS, Braun-Moscovici Y, Mayes MD, McNearney TA, Hsu V, Clements PJ, Furst DE.

Arthritis Rheum. 2007 Oct 15;57(7):1280-6.


Treatment of inflamed pancreas with enkephalin encoding HSV-1 recombinant vector reduces inflammatory damage and behavioral sequelae.

Lu Y, McNearney TA, Lin W, Wilson SP, Yeomans DC, Westlund KN.

Mol Ther. 2007 Oct;15(10):1812-9. Epub 2007 Jun 12.


Transcutaneous electrical nerve stimulation (TENS) improves upper GI symptoms and balances the sympathovagal activity in scleroderma patients.

Sallam H, McNearney TA, Doshi D, Chen JD.

Dig Dis Sci. 2007 May;52(5):1329-37. Epub 2007 Mar 20.


Pulmonary involvement in systemic sclerosis: associations with genetic, serologic, sociodemographic, and behavioral factors.

McNearney TA, Reveille JD, Fischbach M, Friedman AW, Lisse JR, Goel N, Tan FK, Zhou X, Ahn C, Feghali-Bostwick CA, Fritzler M, Arnett FC, Mayes MD.

Arthritis Rheum. 2007 Mar 15;57(2):318-26.


Association of the PTPN22 R620W polymorphism with anti-topoisomerase I- and anticentromere antibody-positive systemic sclerosis.

Gourh P, Tan FK, Assassi S, Ahn CW, McNearney TA, Fischbach M, Arnett FC, Mayes MD.

Arthritis Rheum. 2006 Dec;54(12):3945-53.


Primary care house staff attitudes toward osteoporosis management.

McNearney TA, Shepherd AJ, Chhabra A, Goel N.

South Med J. 2006 May;99(5):461-6.


Thermosensitive TRP ion channels mediate cytosolic calcium response in human synoviocytes.

Kochukov MY, McNearney TA, Fu Y, Westlund KN.

Am J Physiol Cell Physiol. 2006 Sep;291(3):C424-32. Epub 2006 Apr 5.


Systematic review: pathophysiology and management of gastrointestinal dysmotility in systemic sclerosis (scleroderma).

Sallam H, McNearney TA, Chen JD.

Aliment Pharmacol Ther. 2006 Mar 15;23(6):691-712. Review.


Proton-sensing G protein-coupled receptor mobilizes calcium in human synovial cells.

Christensen BN, Kochukov M, McNearney TA, Taglialatela G, Westlund KN.

Am J Physiol Cell Physiol. 2005 Sep;289(3):C601-8. Epub 2005 Apr 13. Erratum in: Am J Physiol Cell Physiol. 2006 Feb;290(2):C660.


Expression of complement receptor 2 (CR2) on HTLV-1-infected lymphocytes and transformed cell lines.

McNearney TA, Ebenbichler CF, Tötsch M, Dierich MP.

Eur J Immunol. 1993 Jun;23(6):1266-70.


The rat basophilic leukemia cell receptor for IgE. I. Characterization as a glycoprotein.

Kulczycki A Jr, McNearney TA, Parker CW.

J Immunol. 1976 Aug;117(2):661-5.


Studies on the stimulation of cAMP metabolism in human lymphocytes by latex polymers.

Atkinson JP, Greene WC, McNearney TA, Parker CW.

Exp Cell Res. 1976 May;99(2):395-407. No abstract available.


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