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Items: 1 to 20 of 108

1.

Improved transplant survival and long-term disease outcome in children with MHC class II deficiency.

Lum SH, Anderson C, McNaughton P, Engelhardt KR, MacKenzie B, Watson H, Al-Mousa H, Al-Herz W, Al-Saud B, Mohammed R, Al-Zahrani DM, Alghamdi HA, Goronfolah L, Nademi Z, Habibollah S, Flinn AM, Shillitoe B, Owens S, Williams E, Emonts M, Hambleton S, Abinun M, Flood T, Cant A, Gennery AR, Slatter M.

Blood. 2020 Mar 19;135(12):954-973. doi: 10.1182/blood.2019002690.

PMID:
31932845
2.

HCN3 ion channels: roles in sensory neuronal excitability and pain.

Lainez S, Tsantoulas C, Biel M, McNaughton PA.

J Physiol. 2019 Sep;597(17):4661-4675. doi: 10.1113/JP278211. Epub 2019 Jul 27.

PMID:
31290157
3.

A randomised, double-blind, placebo-controlled crossover trial of the influence of the HCN channel blocker ivabradine in a healthy volunteer pain model: an enriched population trial.

Lee MC, Bond S, Wheeler D, Scholtes I, Armstrong G, McNaughton P, Menon D.

Pain. 2019 Nov;160(11):2554-2565. doi: 10.1097/j.pain.0000000000001638.

PMID:
31188268
4.

Two decades of excellent transplant survival for chronic granulomatous disease: a supraregional immunology transplant center report.

Lum SH, Flood T, Hambleton S, McNaughton P, Watson H, Abinun M, Owens S, Cigrovski N, Cant A, Gennery AR, Slatter M.

Blood. 2019 Jun 6;133(23):2546-2549. doi: 10.1182/blood.2019000021. Epub 2019 Apr 5. No abstract available.

PMID:
30952673
5.

TRPM2 and warmth sensation.

Tan CH, McNaughton PA.

Pflugers Arch. 2018 May;470(5):787-798. doi: 10.1007/s00424-018-2139-7. Epub 2018 Mar 19. Review.

6.

Hyperpolarization-activated cyclic nucleotide-gated 2 (HCN2) ion channels drive pain in mouse models of diabetic neuropathy.

Tsantoulas C, Laínez S, Wong S, Mehta I, Vilar B, McNaughton PA.

Sci Transl Med. 2017 Sep 27;9(409):eaam6072. doi: 10.1126/scitranslmed.aam6072.

7.

Sensitization of TRPA1 by Protein Kinase A.

Meents JE, Fischer MJ, McNaughton PA.

PLoS One. 2017 Jan 11;12(1):e0170097. doi: 10.1371/journal.pone.0170097. eCollection 2017.

8.

HCN2 ion channels: basic science opens up possibilities for therapeutic intervention in neuropathic pain.

Tsantoulas C, Mooney ER, McNaughton PA.

Biochem J. 2016 Sep 15;473(18):2717-36. doi: 10.1042/BCJ20160287. Review.

PMID:
27621481
9.

The TRPM2 ion channel is required for sensitivity to warmth.

Tan CH, McNaughton PA.

Nature. 2016 Aug 25;536(7617):460-3. Epub 2016 Aug 17.

10.

Agonist-induced sensitisation of the irritant receptor ion channel TRPA1.

Meents JE, Fischer MJ, McNaughton PA.

J Physiol. 2016 Nov 15;594(22):6643-6660. doi: 10.1113/JP272237. Epub 2016 Aug 4.

11.

Inflammatory and neuropathic pain are rapidly suppressed by peripheral block of hyperpolarisation-activated cyclic nucleotide-gated ion channels.

Young GT, Emery EC, Mooney ER, Tsantoulas C, McNaughton PA.

Pain. 2014 Sep;155(9):1708-19. doi: 10.1016/j.pain.2014.05.021. Epub 2014 May 23.

PMID:
24861581
12.

How anchoring proteins shape pain.

Fischer MJ, McNaughton PA.

Pharmacol Ther. 2014 Sep;143(3):316-22. doi: 10.1016/j.pharmthera.2014.04.001. Epub 2014 Apr 12. Review.

PMID:
24727631
13.

Direct evidence for functional TRPV1/TRPA1 heteromers.

Fischer MJ, Balasuriya D, Jeggle P, Goetze TA, McNaughton PA, Reeh PW, Edwardson JM.

Pflugers Arch. 2014 Dec;466(12):2229-41. doi: 10.1007/s00424-014-1497-z. Epub 2014 Mar 19.

PMID:
24643480
14.

Mapping the binding site of TRPV1 on AKAP79: implications for inflammatory hyperalgesia.

Btesh J, Fischer MJM, Stott K, McNaughton PA.

J Neurosci. 2013 May 22;33(21):9184-9193. doi: 10.1523/JNEUROSCI.4991-12.2013. Erratum in: J Neurosci. 2015 May 27;35(21):8377.

15.

Disrupting sensitization of transient receptor potential vanilloid subtype 1 inhibits inflammatory hyperalgesia.

Fischer MJ, Btesh J, McNaughton PA.

J Neurosci. 2013 Apr 24;33(17):7407-14. doi: 10.1523/JNEUROSCI.3721-12.2013.

16.

Magnetic characterization of isolated candidate vertebrate magnetoreceptor cells.

Eder SH, Cadiou H, Muhamad A, McNaughton PA, Kirschvink JL, Winklhofer M.

Proc Natl Acad Sci U S A. 2012 Jul 24;109(30):12022-7. doi: 10.1073/pnas.1205653109. Epub 2012 Jul 9.

17.

Direct inhibition of the cold-activated TRPM8 ion channel by Gαq.

Zhang X, Mak S, Li L, Parra A, Denlinger B, Belmonte C, McNaughton PA.

Nat Cell Biol. 2012 Aug;14(8):851-8. doi: 10.1038/ncb2529. Epub 2012 Jul 1.

18.

HCN2 ion channels: an emerging role as the pacemakers of pain.

Emery EC, Young GT, McNaughton PA.

Trends Pharmacol Sci. 2012 Aug;33(8):456-63. doi: 10.1016/j.tips.2012.04.004. Epub 2012 May 19. Review.

PMID:
22613784
19.

HCN2 ion channels play a central role in inflammatory and neuropathic pain.

Emery EC, Young GT, Berrocoso EM, Chen L, McNaughton PA.

Science. 2011 Sep 9;333(6048):1462-6. doi: 10.1126/science.1206243.

20.

The thermo-TRP ion channel family: properties and therapeutic implications.

Vay L, Gu C, McNaughton PA.

Br J Pharmacol. 2012 Feb;165(4):787-801. doi: 10.1111/j.1476-5381.2011.01601.x. Review.

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