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Items: 46


The Microtubule Severing Protein Katanin Regulates Proliferation of Neuronal Progenitors in Embryonic and Adult Neurogenesis.

Lombino FL, Muhia M, Lopez-Rojas J, Brill MS, Thies E, Ruschkies L, Lutz D, Richter M, Hausrat TJ, Lopes AT, McNally FJ, Hermans-Borgmeyer I, Dunleavy JEM, Hoffmeister-Ullerich S, Frotscher M, Misgeld T, Kreutz MR, de Anda FC, Kneussel M.

Sci Rep. 2019 Nov 4;9(1):15940. doi: 10.1038/s41598-019-52367-3.


Spherical spindle shape promotes perpendicular cortical orientation by preventing isometric cortical pulling on both spindle poles during C. elegans female meiosis.

Vargas E, McNally KP, Cortes DB, Panzica MT, Danlasky BM, Li Q, Maddox AS, McNally FJ.

Development. 2019 Oct 21;146(20). pii: dev178863. doi: 10.1242/dev.178863.


Microtubule-severing enzymes: From cellular functions to molecular mechanism.

McNally FJ, Roll-Mecak A.

J Cell Biol. 2018 Dec 3;217(12):4057-4069. doi: 10.1083/jcb.201612104. Epub 2018 Oct 29. Review.


Structural basis for disassembly of katanin heterododecamers.

Nithianantham S, McNally FJ, Al-Bassam J.

J Biol Chem. 2018 Jul 6;293(27):10590-10605. doi: 10.1074/jbc.RA117.001215. Epub 2018 May 11.


Mechanisms that prevent catastrophic interactions between paternal chromosomes and the oocyte meiotic spindle.

Panzica MT, McNally FJ.

Cell Cycle. 2018;17(5):529-534. doi: 10.1080/15384101.2018.1431495. Epub 2018 Feb 22. Review.


Competing chromosomes explain junk DNA.

McNally FJ.

Science. 2017 Nov 3;358(6363):594-595. doi: 10.1126/science.aaq0200. No abstract available.


Autosomal Trisomy and Triploidy Are Corrected During Female Meiosis in Caenorhabditis elegans.

Vargas E, McNally K, Friedman JA, Cortes DB, Wang DY, Korf IF, McNally FJ.

Genetics. 2017 Nov;207(3):911-922. doi: 10.1534/genetics.117.300259. Epub 2017 Sep 7.


A casein kinase 1 prevents expulsion of the oocyte meiotic spindle into a polar body by regulating cortical contractility.

Flynn JR, McNally FJ.

Mol Biol Cell. 2017 Sep 1;28(18):2410-2419. doi: 10.1091/mbc.E17-01-0056. Epub 2017 Jul 12.


F-actin prevents interaction between sperm DNA and the oocyte meiotic spindle in C. elegans.

Panzica MT, Marin HC, Reymann AC, McNally FJ.

J Cell Biol. 2017 Aug 7;216(8):2273-2282. doi: 10.1083/jcb.201702020. Epub 2017 Jun 21.


A novel chromosome segregation mechanism during female meiosis.

McNally KP, Panzica MT, Kim T, Cortes DB, McNally FJ.

Mol Biol Cell. 2016 Aug 15;27(16):2576-89. doi: 10.1091/mbc.E16-05-0331. Epub 2016 Jun 22.


Dynactin-dependent cortical dynein and spherical spindle shape correlate temporally with meiotic spindle rotation in Caenorhabditis elegans.

Crowder ME, Flynn JR, McNally KP, Cortes DB, Price KL, Kuehnert PA, Panzica MT, Andaya A, Leary JA, McNally FJ.

Mol Biol Cell. 2015 Sep 1;26(17):3030-46. doi: 10.1091/mbc.E15-05-0290. Epub 2015 Jul 1.


The asymmetry of female meiosis reduces the frequency of inheritance of unpaired chromosomes.

Cortes DB, McNally KL, Mains PE, McNally FJ.

Elife. 2015 Apr 7;4:e06056. doi: 10.7554/eLife.06056.


Katanin maintains meiotic metaphase chromosome alignment and spindle structure in vivo and has multiple effects on microtubules in vitro.

McNally K, Berg E, Cortes DB, Hernandez V, Mains PE, McNally FJ.

Mol Biol Cell. 2014 Apr;25(7):1037-49. doi: 10.1091/mbc.E13-12-0764. Epub 2014 Feb 5.


Mechanisms of spindle positioning.

McNally FJ.

J Cell Biol. 2013 Jan 21;200(2):131-40. doi: 10.1083/jcb.201210007. Review.


An essential role for katanin p80 and microtubule severing in male gamete production.

O'Donnell L, Rhodes D, Smith SJ, Merriner DJ, Clark BJ, Borg C, Whittle B, O'Connor AE, Smith LB, McNally FJ, de Kretser DM, Goodnow CC, Ormandy CJ, Jamsai D, O'Bryan MK.

PLoS Genet. 2012;8(5):e1002698. doi: 10.1371/journal.pgen.1002698. Epub 2012 May 24.


Kinesin-1 prevents capture of the oocyte meiotic spindle by the sperm aster.

McNally KL, Fabritius AS, Ellefson ML, Flynn JR, Milan JA, McNally FJ.

Dev Cell. 2012 Apr 17;22(4):788-98. doi: 10.1016/j.devcel.2012.01.010. Epub 2012 Mar 29.


Katanin contributes to interspecies spindle length scaling in Xenopus.

Loughlin R, Wilbur JD, McNally FJ, Nédélec FJ, Heald R.

Cell. 2011 Dec 9;147(6):1397-407. doi: 10.1016/j.cell.2011.11.014.


Initial diameter of the polar body contractile ring is minimized by the centralspindlin complex.

Fabritius AS, Flynn JR, McNally FJ.

Dev Biol. 2011 Nov 1;359(1):137-148. doi: 10.1016/j.ydbio.2011.08.013. Epub 2011 Aug 25.


CDK-1 inhibits meiotic spindle shortening and dynein-dependent spindle rotation in C. elegans.

Ellefson ML, McNally FJ.

J Cell Biol. 2011 Jun 27;193(7):1229-44. doi: 10.1083/jcb.201104008. Epub 2011 Jun 20.


The spindle assembly function of Caenorhabditis elegans katanin does not require microtubule-severing activity.

McNally KP, McNally FJ.

Mol Biol Cell. 2011 May;22(9):1550-60. doi: 10.1091/mbc.E10-12-0951. Epub 2011 Mar 3. Erratum in: Mol Biol Cell. 2012 Nov;23(22):4472.


Nuclear and spindle positioning during oocyte meiosis.

Fabritius AS, Ellefson ML, McNally FJ.

Curr Opin Cell Biol. 2011 Feb;23(1):78-84. doi: 10.1016/ Epub 2010 Aug 11. Review.


Kinesin-dependent transport results in polarized migration of the nucleus in oocytes and inward movement of yolk granules in meiotic embryos.

McNally KL, Martin JL, Ellefson M, McNally FJ.

Dev Biol. 2010 Mar 1;339(1):126-40. doi: 10.1016/j.ydbio.2009.12.021. Epub 2009 Dec 28.


Microtubule-severing enzymes.

Roll-Mecak A, McNally FJ.

Curr Opin Cell Biol. 2010 Feb;22(1):96-103. doi: 10.1016/ Epub 2009 Dec 5. Review.


UNC-83 is a nuclear-specific cargo adaptor for kinesin-1-mediated nuclear migration.

Meyerzon M, Fridolfsson HN, Ly N, McNally FJ, Starr DA.

Development. 2009 Aug;136(16):2725-33. doi: 10.1242/dev.038596. Epub 2009 Jul 15.


Levels of the ubiquitin ligase substrate adaptor MEL-26 are inversely correlated with MEI-1/katanin microtubule-severing activity during both meiosis and mitosis.

Johnson JL, Lu C, Raharjo E, McNally K, McNally FJ, Mains PE.

Dev Biol. 2009 Jun 15;330(2):349-57. doi: 10.1016/j.ydbio.2009.04.004. Epub 2009 Apr 8.


Kinesin-1 and cytoplasmic dynein act sequentially to move the meiotic spindle to the oocyte cortex in Caenorhabditis elegans.

Ellefson ML, McNally FJ.

Mol Biol Cell. 2009 Jun;20(11):2722-30. doi: 10.1091/mbc.E08-12-1253. Epub 2009 Apr 8.


Katanin controls mitotic and meiotic spindle length.

McNally K, Audhya A, Oegema K, McNally FJ.

J Cell Biol. 2006 Dec 18;175(6):881-91.


Katanin-mediated microtubule severing can be regulated by multiple mechanisms.

McNally KP, Buster D, McNally FJ.

Cell Motil Cytoskeleton. 2002 Dec;53(4):337-49.


Katanin inhibition prevents the redistribution of gamma-tubulin at mitosis.

Buster D, McNally K, McNally FJ.

J Cell Sci. 2002 Mar 1;115(Pt 5):1083-92.


Cytoskeleton: CLASPing the end to the edge.

McNally FJ.

Curr Biol. 2001 Jun 26;11(12):R477-80.


MEI-1/MEI-2 katanin-like microtubule severing activity is required for Caenorhabditis elegans meiosis.

Srayko M, Buster DW, Bazirgan OA, McNally FJ, Mains PE.

Genes Dev. 2000 May 1;14(9):1072-84.


Two domains of p80 katanin regulate microtubule severing and spindle pole targeting by p60 katanin.

McNally KP, Bazirgan OA, McNally FJ.

J Cell Sci. 2000 May;113 ( Pt 9):1623-33.


Microtubule dynamics: Controlling split ends.

McNally FJ.

Curr Biol. 1999 Apr 22;9(8):R274-6. Review.


An essential role for katanin in severing microtubules in the neuron.

Ahmad FJ, Yu W, McNally FJ, Baas PW.

J Cell Biol. 1999 Apr 19;145(2):305-15.


A role for katanin-mediated axonemal severing during Chlamydomonas deflagellation.

Lohret TA, McNally FJ, Quarmby LM.

Mol Biol Cell. 1998 May;9(5):1195-207.


Katanin, a microtubule-severing protein, is a novel AAA ATPase that targets to the centrosome using a WD40-containing subunit.

Hartman JJ, Mahr J, McNally K, Okawa K, Iwamatsu A, Thomas S, Cheesman S, Heuser J, Vale RD, McNally FJ.

Cell. 1998 Apr 17;93(2):277-87.


Katanin, the microtubule-severing ATPase, is concentrated at centrosomes.

McNally FJ, Okawa K, Iwamatsu A, Vale RD.

J Cell Sci. 1996 Mar;109 ( Pt 3):561-7.


Modulation of microtubule dynamics during the cell cycle.

McNally FJ.

Curr Opin Cell Biol. 1996 Feb;8(1):23-9. Review.


Origin recognition complex (ORC) in transcriptional silencing and DNA replication in S. cerevisiae.

Foss M, McNally FJ, Laurenson P, Rine J.

Science. 1993 Dec 17;262(5141):1838-44.


Isolation of the dorsal locus of Drosophila.

Steward R, McNally FJ, Schedl P.

Nature. 1984 Sep 20-26;311(5983):262-5.


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