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Plasmids Shaped the Recent Emergence of the Major Nosocomial Pathogen Enterococcus faecium.

Arredondo-Alonso S, Top J, McNally A, Puranen S, Pesonen M, Pensar J, Marttinen P, Braat JC, Rogers MRC, van Schaik W, Kaski S, Willems RJL, Corander J, Schürch AC.

mBio. 2020 Feb 11;11(1). pii: e03284-19. doi: 10.1128/mBio.03284-19.


Cobalt-Catalyzed Alkylation of Drug-Like Molecules and Pharmaceuticals Using Heterocyclic Phosphonium Salts.

Zhang X, McNally A.

ACS Catal. 2019 Jun 7;9:4862-4866. doi: 10.1021/acscatal.9b00851. Epub 2019 Apr 22.


The Ecology and Evolution of Pangenomes.

Brockhurst MA, Harrison E, Hall JPJ, Richards T, McNally A, MacLean C.

Curr Biol. 2019 Oct 21;29(20):R1094-R1103. doi: 10.1016/j.cub.2019.08.012. Review.


Handwashing sinks as the source of transmission of ST16 carbapenem-resistant Klebsiella pneumoniae, an international high-risk clone, in an intensive care unit.

Feng Y, Wei L, Zhu S, Qiao F, Zhang X, Kang Y, Cai L, Kang M, McNally A, Zong Z.

J Hosp Infect. 2019 Oct 10. pii: S0195-6701(19)30438-4. doi: 10.1016/j.jhin.2019.10.006. [Epub ahead of print]


Mitsunobu gets a makeover.

McNally A.

Nat Chem. 2019 Nov;11(11):966-967. doi: 10.1038/s41557-019-0362-2. No abstract available.


Nonsymmetrical Bis-Azine Biaryls from Chloroazines: A Strategy Using Phosphorus Ligand-Coupling.

Boyle BT, Hilton MC, McNally A.

J Am Chem Soc. 2019 Sep 25;141(38):15441-15449. doi: 10.1021/jacs.9b08504. Epub 2019 Sep 16.


Key evolutionary events in the emergence of a globally disseminated, carbapenem resistant clone in the Escherichia coli ST410 lineage.

Feng Y, Liu L, Lin J, Ma K, Long H, Wei L, Xie Y, McNally A, Zong Z.

Commun Biol. 2019 Aug 29;2:322. doi: 10.1038/s42003-019-0569-1. eCollection 2019.


A Pyridine-Pyridine Cross-Coupling Reaction via Dearomatized Radical Intermediates.

Koniarczyk JL, Greenwood JW, Alegre-Requena JV, Paton RS, McNally A.

Angew Chem Int Ed Engl. 2019 Oct 14;58(42):14882-14886. doi: 10.1002/anie.201906267. Epub 2019 Sep 9.


The evolution and transmission of multi-drug resistant Escherichia coli and Klebsiella pneumoniae: the complexity of clones and plasmids.

Dunn SJ, Connor C, McNally A.

Curr Opin Microbiol. 2019 Oct;51:51-56. doi: 10.1016/j.mib.2019.06.004. Epub 2019 Jul 17. Review.


Bacterial Microcompartment-Mediated Ethanolamine Metabolism in Escherichia coli Urinary Tract Infection.

Dadswell K, Creagh S, McCullagh E, Liang M, Brown IR, Warren MJ, McNally A, MacSharry J, Prentice MB.

Infect Immun. 2019 Jul 23;87(8). pii: e00211-19. doi: 10.1128/IAI.00211-19. Print 2019 Aug.


Antibiotic resistance genes are abundant and diverse in raw sewage used for urban agriculture in Africa and associated with urban population density.

Bougnom BP, McNally A, Etoa FX, Piddock LJ.

Environ Pollut. 2019 Aug;251:146-154. doi: 10.1016/j.envpol.2019.04.056. Epub 2019 Apr 30.


Comparative Transcriptomic Profiling of Yersinia enterocolitica O:3 and O:8 Reveals Major Expression Differences of Fitness- and Virulence-Relevant Genes Indicating Ecological Separation.

Schmühl C, Beckstette M, Heroven AK, Bunk B, Spröer C, McNally A, Overmann J, Dersch P.

mSystems. 2019 Apr 23;4(2). pii: e00239-18. doi: 10.1128/mSystems.00239-18. eCollection 2019 Mar-Apr.


Diversification of Colonization Factors in a Multidrug-Resistant Escherichia coli Lineage Evolving under Negative Frequency-Dependent Selection.

McNally A, Kallonen T, Connor C, Abudahab K, Aanensen DM, Horner C, Peacock SJ, Parkhill J, Croucher NJ, Corander J.

mBio. 2019 Apr 23;10(2). pii: e00644-19. doi: 10.1128/mBio.00644-19.


Identification and typing of Yersinia enterocolitica and Yersinia pseudotuberculosis isolated from human clinical specimens in England between 2004 and 2018.

Hunter E, Greig DR, Schaefer U, Wright MJ, Dallman TJ, McNally A, Jenkins C.

J Med Microbiol. 2019 Apr;68(4):538-548. doi: 10.1099/jmm.0.000943. Epub 2019 Mar 19.


Genomic and Functional Analysis of Emerging Virulent and Multidrug-Resistant Escherichia coli Lineage Sequence Type 648.

Schaufler K, Semmler T, Wieler LH, Trott DJ, Pitout J, Peirano G, Bonnedahl J, Dolejska M, Literak I, Fuchs S, Ahmed N, Grobbel M, Torres C, McNally A, Pickard D, Ewers C, Croucher NJ, Corander J, Guenther S.

Antimicrob Agents Chemother. 2019 May 24;63(6). pii: e00243-19. doi: 10.1128/AAC.00243-19. Print 2019 Jun.


Do we really understand how faecal microbiota transplantation works?

Quraishi MN, McNally A, van Schaik W.

EBioMedicine. 2019 Apr;42:39. doi: 10.1016/j.ebiom.2019.03.024. Epub 2019 Mar 16. No abstract available.


NDM Metallo-β-Lactamases and Their Bacterial Producers in Health Care Settings.

Wu W, Feng Y, Tang G, Qiao F, McNally A, Zong Z.

Clin Microbiol Rev. 2019 Jan 30;32(2). pii: e00115-18. doi: 10.1128/CMR.00115-18. Print 2019 Mar 20. Review.


Acquisition and Loss of CTX-M-Producing and Non-Producing Escherichia coli in the Fecal Microbiome of Travelers to South Asia.

Bevan ER, McNally A, Thomas CM, Piddock LJV, Hawkey PM.

mBio. 2018 Dec 11;9(6). pii: e02408-18. doi: 10.1128/mBio.02408-18.


Coexistence of three blaKPC-2 genes on an IncF/IncR plasmid in ST11 Klebsiella pneumoniae.

Feng Y, Liu L, McNally A, Zong Z.

J Glob Antimicrob Resist. 2019 Jun;17:90-93. doi: 10.1016/j.jgar.2018.11.017. Epub 2018 Nov 26.


Selective formation of heteroaryl thioethers via a phosphonium ion coupling reaction.

Anderson RG, Jett BM, McNally A.

Tetrahedron. 2018 Jun 21;74(25):3129-3136. doi: 10.1016/j.tet.2017.12.040. Epub 2017 Dec 21.


Heterobiaryl synthesis by contractive C-C coupling via P(V) intermediates.

Hilton MC, Zhang X, Boyle BT, Alegre-Requena JV, Paton RS, McNally A.

Science. 2018 Nov 16;362(6416):799-804. doi: 10.1126/science.aas8961.


Effect of simulated joint instability and bracing on ankle and subtalar joint flexibility.

Choisne J, McNally A, Hoch MC, Ringleb SI.

J Biomech. 2019 Jan 3;82:234-243. doi: 10.1016/j.jbiomech.2018.10.033. Epub 2018 Nov 2.


The Occurence of Colistin-Resistant Hypervirulent Klebsiella pneumoniae in China.

Lu Y, Feng Y, McNally A, Zong Z.

Front Microbiol. 2018 Oct 25;9:2568. doi: 10.3389/fmicb.2018.02568. eCollection 2018.


Genomic epidemiology of clinical Campylobacter spp. at a single health trust site.

Dunn SJ, Pascoe B, Turton J, Fleming V, Diggle M, Sheppard SK, McNally A, Manning G.

Microb Genom. 2018 Oct;4(10). doi: 10.1099/mgen.0.000227. Epub 2018 Oct 11.


Wastewater used for urban agriculture in West Africa as a reservoir for antibacterial resistance dissemination.

Bougnom BP, Zongo C, McNally A, Ricci V, Etoa FX, Thiele-Bruhn S, Piddock LJV.

Environ Res. 2019 Jan;168:14-24. doi: 10.1016/j.envres.2018.09.022. Epub 2018 Sep 18.


The impact of alcohol use disorders on pulmonary immune cell inflammatory responses to Streptococcus pneumoniae.

Gaydos J, McNally A, Burnham EL.

Alcohol. 2019 Nov;80:119-130. doi: 10.1016/j.alcohol.2018.08.016. Epub 2018 Sep 5.


Effect of arteriovenous graft flow rate on vascular access hemodynamics in a novel modular anastomotic valve device.

McNally A, Akingba AG, Sucosky P.

J Vasc Access. 2018 Sep;19(5):446-454. doi: 10.1177/1129729818758229. Epub 2018 Mar 1.


A Unified Approach to Couple Aromatic Heteronucleophiles to Azines and Pharmaceuticals.

Anderson RG, Jett BM, McNally A.

Angew Chem Int Ed Engl. 2018 Sep 17;57(38):12514-12518. doi: 10.1002/anie.201807322. Epub 2018 Aug 27.


Occurrence of colistin-resistant hypervirulent Klebsiella variicola.

Lu Y, Feng Y, McNally A, Zong Z.

J Antimicrob Chemother. 2018 Nov 1;73(11):3001-3004. doi: 10.1093/jac/dky301.


blaNDM-21, a new variant of blaNDM in an Escherichia coli clinical isolate carrying blaCTX-M-55 and rmtB.

Liu L, Feng Y, McNally A, Zong Z.

J Antimicrob Chemother. 2018 Sep 1;73(9):2336-2339. doi: 10.1093/jac/dky226.


Complete genomic characterization of two Escherichia coli lineages responsible for a cluster of carbapenem-resistant infections in a Chinese hospital.

Zong Z, Fenn S, Connor C, Feng Y, McNally A.

J Antimicrob Chemother. 2018 Sep 1;73(9):2340-2346. doi: 10.1093/jac/dky210.


Site-Selective Switching Strategies to Functionalize Polyazines.

Dolewski RD, Fricke PJ, McNally A.

J Am Chem Soc. 2018 Jun 27;140(25):8020-8026. doi: 10.1021/jacs.8b04530. Epub 2018 May 24.


Identification of Mycobacterium chimaera in heater-cooler units in China.

Zhang X, Lin J, Feng Y, Wang X, McNally A, Zong Z.

Sci Rep. 2018 May 18;8(1):7843. doi: 10.1038/s41598-018-26289-5.


Clinically Relevant Plasmid-Host Interactions Indicate that Transcriptional and Not Genomic Modifications Ameliorate Fitness Costs of Klebsiella pneumoniae Carbapenemase-Carrying Plasmids.

Buckner MMC, Saw HTH, Osagie RN, McNally A, Ricci V, Wand ME, Woodford N, Ivens A, Webber MA, Piddock LJV.

mBio. 2018 Apr 24;9(2). pii: e02303-17. doi: 10.1128/mBio.02303-17.


A Strategy to Aminate Pyridines, Diazines, and Pharmaceuticals via Heterocyclic Phosphonium Salts.

Patel C, Mohnike M, Hilton MC, McNally A.

Org Lett. 2018 May 4;20(9):2607-2610. doi: 10.1021/acs.orglett.8b00813. Epub 2018 Apr 17.


Sequence Type 273 Carbapenem-Resistant Klebsiella pneumoniae Carrying blaNDM-1 and blaIMP-4.

Liu L, Feng Y, Long H, McNally A, Zong Z.

Antimicrob Agents Chemother. 2018 May 25;62(6). pii: e00160-18. doi: 10.1128/AAC.00160-18. Print 2018 Jun.


Observational cohort study of outcomes in patients admitted to the intensive care unit for acute exacerbation of chronic obstructive pulmonary disease.

Sivakumar S, McNally A, Tobin J, Williamson J, Aneman A.

Intern Med J. 2018 Aug;48(8):944-950. doi: 10.1111/imj.13805.


Convergent Amino Acid Signatures in Polyphyletic Campylobacter jejuni Subpopulations Suggest Human Niche Tropism.

Méric G, McNally A, Pessia A, Mourkas E, Pascoe B, Mageiros L, Vehkala M, Corander J, Sheppard SK.

Genome Biol Evol. 2018 Mar 1;10(3):763-774. doi: 10.1093/gbe/evy026.


Coexistence of Two blaNDM-5 Genes on an IncF Plasmid as Revealed by Nanopore Sequencing.

Feng Y, Liu L, McNally A, Zong Z.

Antimicrob Agents Chemother. 2018 Apr 26;62(5). pii: e00110-18. doi: 10.1128/AAC.00110-18. Print 2018 May.


Integrating the social, hydrological and ecological dimensions of freshwater health: The Freshwater Health Index.

Vollmer D, Shaad K, Souter NJ, Farrell T, Dudgeon D, Sullivan CA, Fauconnier I, MacDonald GM, McCartney MP, Power AG, McNally A, Andelman SJ, Capon T, Devineni N, Apirumanekul C, Ng CN, Rebecca Shaw M, Wang RY, Lai C, Wang Z, Regan HM.

Sci Total Environ. 2018 Jun 15;627:304-313. doi: 10.1016/j.scitotenv.2018.01.040. Epub 2018 Feb 3.


A General Strategy for Site-Selective Incorporation of Deuterium and Tritium into Pyridines, Diazines, and Pharmaceuticals.

Koniarczyk JL, Hesk D, Overgard A, Davies IW, McNally A.

J Am Chem Soc. 2018 Feb 14;140(6):1990-1993. doi: 10.1021/jacs.7b11710. Epub 2018 Feb 5.


Cryptic transmission of ST405 Escherichia coli carrying bla NDM-4 in hospital.

Zhang X, Feng Y, Zhou W, McNally A, Zong Z.

Sci Rep. 2018 Jan 10;8(1):390. doi: 10.1038/s41598-017-18910-w.


Synthetic transcription elongation factors license transcription across repressive chromatin.

Erwin GS, Grieshop MP, Ali A, Qi J, Lawlor M, Kumar D, Ahmad I, McNally A, Teider N, Worringer K, Sivasankaran R, Syed DN, Eguchi A, Ashraf M, Jeffery J, Xu M, Park PMC, Mukhtar H, Srivastava AK, Faruq M, Bradner JE, Ansari AZ.

Science. 2017 Dec 22;358(6370):1617-1622. doi: 10.1126/science.aan6414. Epub 2017 Nov 30.


Phylogeographic separation and formation of sexually discrete lineages in a global population of Yersinia pseudotuberculosis.

Seecharran T, Kalin-Manttari L, Koskela K, Nikkari S, Dickins B, Corander J, Skurnik M, McNally A.

Microb Genom. 2017 Sep 18;3(10):e000133. doi: 10.1099/mgen.0.000133. eCollection 2017 Oct.


Reply to 'The population genetics of pangenomes'.

McInerney JO, McNally A, O'Connell MJ.

Nat Microbiol. 2017 Dec;2(12):1575. doi: 10.1038/s41564-017-0068-4. No abstract available.


Occurrence of Enterobacter hormaechei carrying blaNDM-1 and blaKPC-2 in China.

Yang B, Feng Y, McNally A, Zong Z.

Diagn Microbiol Infect Dis. 2018 Feb;90(2):139-142. doi: 10.1016/j.diagmicrobio.2017.10.007. Epub 2017 Oct 19.


Remarkable Diversity of Escherichia coli Carrying mcr-1 from Hospital Sewage with the Identification of Two New mcr-1 Variants.

Zhao F, Feng Y, Lü X, McNally A, Zong Z.

Front Microbiol. 2017 Oct 25;8:2094. doi: 10.3389/fmicb.2017.02094. eCollection 2017.


CERCLA-linked environmental impact and benefit analysis: Evaluating remedial alternatives for the Portland Harbor Superfund Site, Portland, Oregon, USA.

McNally AD, Fitzpatrick AG, Mirchandani S, Salmon M, Edwards DA.

Integr Environ Assess Manag. 2018 Jan;14(1):22-31. doi: 10.1002/ieam.2000. Epub 2017 Dec 6.


Stakeholder value-linked sustainability assessment: Evaluating remedial alternatives for the Portland Harbor Superfund Site, Portland, Oregon, USA.

Apitz SE, Fitzpatrick AG, McNally A, Harrison D, Coughlin C, Edwards DA.

Integr Environ Assess Manag. 2018 Jan;14(1):43-62. doi: 10.1002/ieam.1998. Epub 2017 Dec 6.


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