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Items: 1 to 50 of 96

1.

Age at symptom onset and death and disease duration in genetic frontotemporal dementia: an international retrospective cohort study.

Moore KM, Nicholas J, Grossman M, McMillan CT, Irwin DJ, Massimo L, Van Deerlin VM, Warren JD, Fox NC, Rossor MN, Mead S, Bocchetta M, Boeve BF, Knopman DS, Graff-Radford NR, Forsberg LK, Rademakers R, Wszolek ZK, van Swieten JC, Jiskoot LC, Meeter LH, Dopper EG, Papma JM, Snowden JS, Saxon J, Jones M, Pickering-Brown S, Le Ber I, Camuzat A, Brice A, Caroppo P, Ghidoni R, Pievani M, Benussi L, Binetti G, Dickerson BC, Lucente D, Krivensky S, Graff C, Öijerstedt L, Fallström M, Thonberg H, Ghoshal N, Morris JC, Borroni B, Benussi A, Padovani A, Galimberti D, Scarpini E, Fumagalli GG, Mackenzie IR, Hsiung GR, Sengdy P, Boxer AL, Rosen H, Taylor JB, Synofzik M, Wilke C, Sulzer P, Hodges JR, Halliday G, Kwok J, Sanchez-Valle R, Lladó A, Borrego-Ecija S, Santana I, Almeida MR, Tábuas-Pereira M, Moreno F, Barandiaran M, Indakoetxea B, Levin J, Danek A, Rowe JB, Cope TE, Otto M, Anderl-Straub S, de Mendonça A, Maruta C, Masellis M, Black SE, Couratier P, Lautrette G, Huey ED, Sorbi S, Nacmias B, Laforce R Jr, Tremblay ML, Vandenberghe R, Damme PV, Rogalski EJ, Weintraub S, Gerhard A, Onyike CU, Ducharme S, Papageorgiou SG, Ng ASL, Brodtmann A, Finger E, Guerreiro R, Bras J, Rohrer JD; FTD Prevention Initiative.

Lancet Neurol. 2020 Feb;19(2):145-156. doi: 10.1016/S1474-4422(19)30394-1. Epub 2019 Dec 3. Erratum in: Lancet Neurol. 2020 Feb;19(2):e2.

2.

Repeat expansions contribute to TDP-43 pathologic heterogeneity in ALS.

Filippi M, McMillan CT.

Neurology. 2019 Nov 5;93(19):823-824. doi: 10.1212/WNL.0000000000008436. Epub 2019 Oct 16. No abstract available.

PMID:
31619482
3.

Diffusion Tensor MRI to Distinguish Progressive Supranuclear Palsy from α-Synucleinopathies.

Spotorno N, Hall S, Irwin DJ, Rumetshofer T, Acosta-Cabronero J, Deik AF, Spindler MA, Lee EB, Trojanowski JQ, van Westen D, Nilsson M, Grossman M, Nestor PJ, McMillan CT, Hansson O.

Radiology. 2019 Dec;293(3):646-653. doi: 10.1148/radiol.2019190406. Epub 2019 Oct 15.

4.

Genetic predictors of survival in behavioral variant frontotemporal degeneration.

Caswell C, McMillan CT, Xie SX, Van Deerlin VM, Suh E, Lee EB, Trojanowski JQ, Lee VM, Irwin DJ, Grossman M, Massimo LM.

Neurology. 2019 Oct 29;93(18):e1707-e1714. doi: 10.1212/WNL.0000000000008387. Epub 2019 Sep 19.

PMID:
31537715
5.

Empiric Methods to Account for Pre-analytical Variability in Digital Histopathology in Frontotemporal Lobar Degeneration.

Giannini LAA, Xie SX, Peterson C, Zhou C, Lee EB, Wolk DA, Grossman M, Trojanowski JQ, McMillan CT, Irwin DJ.

Front Neurosci. 2019 Jul 3;13:682. doi: 10.3389/fnins.2019.00682. eCollection 2019.

6.

Longitudinal progression of grey matter atrophy in non-amnestic Alzheimer's disease.

Phillips JS, Da Re F, Irwin DJ, McMillan CT, Vaishnavi SN, Xie SX, Lee EB, Cook PA, Gee JC, Shaw LM, Trojanowski JQ, Wolk DA, Grossman M.

Brain. 2019 Jun 1;142(6):1701-1722. doi: 10.1093/brain/awz091.

PMID:
31135048
7.

Clinical Correlates of Alzheimer's Disease Cerebrospinal Fluid Analytes in Primary Progressive Aphasia.

Norise C, Ungrady M, Halpin A, Jester C, McMillan CT, Irwin DJ, Cousins KA, Grossman M.

Front Neurol. 2019 May 10;10:485. doi: 10.3389/fneur.2019.00485. eCollection 2019.

8.

Clinical value of cerebrospinal fluid neurofilament light chain in semantic dementia.

Meeter LHH, Steketee RME, Salkovic D, Vos ME, Grossman M, McMillan CT, Irwin DJ, Boxer AL, Rojas JC, Olney NT, Karydas A, Miller BL, Pijnenburg YAL, Barkhof F, Sánchez-Valle R, Lladó A, Borrego-Ecija S, Diehl-Schmid J, Grimmer T, Goldhardt O, Santillo AF, Hansson O, Vestberg S, Borroni B, Padovani A, Galimberti D, Scarpini E, Rohrer JD, Woollacott IOC, Synofzik M, Wilke C, de Mendonca A, Vandenberghe R, Benussi L, Ghidoni R, Binetti G, Niessen WJ, Papma JM, Seelaar H, Jiskoot LC, de Jong FJ, Donker Kaat L, Del Campo M, Teunissen CE, Bron EE, Van den Berg E, Van Swieten JC.

J Neurol Neurosurg Psychiatry. 2019 Sep;90(9):997-1004. doi: 10.1136/jnnp-2018-319784. Epub 2019 May 23.

9.

A longitudinal study of speech production in primary progressive aphasia and behavioral variant frontotemporal dementia.

Ash S, Nevler N, Phillips J, Irwin DJ, McMillan CT, Rascovsky K, Grossman M.

Brain Lang. 2019 Jul;194:46-57. doi: 10.1016/j.bandl.2019.04.006. Epub 2019 May 7.

PMID:
31075725
10.

Divergent patterns of TDP-43 and tau pathologies in primary progressive aphasia.

Giannini LAA, Xie SX, McMillan CT, Liang M, Williams A, Jester C, Rascovsky K, Wolk DA, Ash S, Lee EB, Trojanowski JQ, Grossman M, Irwin DJ.

Ann Neurol. 2019 May;85(5):630-643. doi: 10.1002/ana.25465. Epub 2019 Mar 28.

PMID:
30851133
11.

Cognitive and Pathological Influences of Tau Pathology in Lewy Body Disorders.

Coughlin D, Xie SX, Liang M, Williams A, Peterson C, Weintraub D, McMillan CT, Wolk DA, Akhtar RS, Hurtig HI, Branch Coslett H, Hamilton RH, Siderowf AD, Duda JE, Rascovsky K, Lee EB, Lee VM, Grossman M, Trojanowski JQ, Irwin DJ.

Ann Neurol. 2019 Feb;85(2):259-271. doi: 10.1002/ana.25392. Epub 2019 Jan 7.

12.

UNC13A polymorphism contributes to frontotemporal disease in sporadic amyotrophic lateral sclerosis.

Placek K, Baer GM, Elman L, McCluskey L, Hennessy L, Ferraro PM, Lee EB, Lee VMY, Trojanowski JQ, Van Deerlin VM, Grossman M, Irwin DJ, McMillan CT.

Neurobiol Aging. 2019 Jan;73:190-199. doi: 10.1016/j.neurobiolaging.2018.09.031. Epub 2018 Sep 27.

13.

Elevated YKL-40 and low sAPPβ:YKL-40 ratio in antemortem cerebrospinal fluid of patients with pathologically confirmed FTLD.

Alcolea D, Irwin DJ, Illán-Gala I, Muñoz L, Clarimón J, McMillan CT, Fortea J, Blesa R, Lee EB, Trojanowski JQ, Grossman M, Lleó A.

J Neurol Neurosurg Psychiatry. 2019 Feb;90(2):180-186. doi: 10.1136/jnnp-2018-318993. Epub 2018 Oct 8.

14.

Modifiable vascular risk factors, white matter disease and cognition in early Parkinson's disease.

Chahine LM, Dos Santos C, Fullard M, Scordia C, Weintraub D, Erus G, Rosenthal L, Davatzikos C, McMillan CT.

Eur J Neurol. 2019 Feb;26(2):246-e18. doi: 10.1111/ene.13797. Epub 2018 Oct 28.

15.

Alzheimer's genetic risk is reduced in primary age-related tauopathy: a potential model of resistance?

McMillan CT, Lee EB, Jefferson-George K, Naj A, Van Deerlin VM, Trojanowski JQ, Wolk DA.

Ann Clin Transl Neurol. 2018 Jun 19;5(8):927-934. doi: 10.1002/acn3.581. eCollection 2018 Aug.

16.

Longitudinal structural gray matter and white matter MRI changes in presymptomatic progranulin mutation carriers.

Olm CA, McMillan CT, Irwin DJ, Van Deerlin VM, Cook PA, Gee JC, Grossman M.

Neuroimage Clin. 2018 May 15;19:497-506. doi: 10.1016/j.nicl.2018.05.017. eCollection 2018.

17.

Neurodegenerative disease concomitant proteinopathies are prevalent, age-related and APOE4-associated.

Robinson JL, Lee EB, Xie SX, Rennert L, Suh E, Bredenberg C, Caswell C, Van Deerlin VM, Yan N, Yousef A, Hurtig HI, Siderowf A, Grossman M, McMillan CT, Miller B, Duda JE, Irwin DJ, Wolk D, Elman L, McCluskey L, Chen-Plotkin A, Weintraub D, Arnold SE, Brettschneider J, Lee VM, Trojanowski JQ.

Brain. 2018 Jul 1;141(7):2181-2193. doi: 10.1093/brain/awy146.

18.

Perfusion alterations converge with patterns of pathological spread in transactive response DNA-binding protein 43 proteinopathies.

Ferraro PM, Jester C, Olm CA, Placek K, Agosta F, Elman L, McCluskey L, Irwin DJ, Detre JA, Filippi M, Grossman M, McMillan CT.

Neurobiol Aging. 2018 Aug;68:85-92. doi: 10.1016/j.neurobiolaging.2018.04.008. Epub 2018 Apr 17.

19.

Amyloid "accumulators": The next generation of candidates for amyloid-targeted clinical trials?

McMillan CT, Chételat G.

Neurology. 2018 Apr 24;90(17):759-760. doi: 10.1212/WNL.0000000000005362. Epub 2018 Mar 23. No abstract available.

PMID:
29572279
20.

A 2-Step Cerebrospinal Algorithm for the Selection of Frontotemporal Lobar Degeneration Subtypes.

Lleó A, Irwin DJ, Illán-Gala I, McMillan CT, Wolk DA, Lee EB, Van Deerlin VM, Shaw LM, Trojanowski JQ, Grossman M.

JAMA Neurol. 2018 Jun 1;75(6):738-745. doi: 10.1001/jamaneurol.2018.0118.

21.

Occupational attainment influences longitudinal decline in behavioral variant frontotemporal degeneration.

Massimo L, Xie SX, Rennert L, Fick DM, Halpin A, Placek K, Williams A, Rascovsky K, Irwin DJ, Grossman M, McMillan CT.

Brain Imaging Behav. 2019 Feb;13(1):293-301. doi: 10.1007/s11682-018-9852-x.

22.

CSF tau and β-amyloid predict cerebral synucleinopathy in autopsied Lewy body disorders.

Irwin DJ, Xie SX, Coughlin D, Nevler N, Akhtar RS, McMillan CT, Lee EB, Wolk DA, Weintraub D, Chen-Plotkin A, Duda JE, Spindler M, Siderowf A, Hurtig HI, Shaw LM, Grossman M, Trojanowski JQ.

Neurology. 2018 Mar 20;90(12):e1038-e1046. doi: 10.1212/WNL.0000000000005166. Epub 2018 Feb 21.

23.

Flortaucipir imaging of MAPT: Mutations emphasize challenges for tau-targeted trials.

McMillan CT, Huey ED.

Neurology. 2018 Mar 13;90(11):495-496. doi: 10.1212/WNL.0000000000005112. Epub 2018 Feb 9. No abstract available.

PMID:
29440565
24.

Asymmetry of post-mortem neuropathology in behavioural-variant frontotemporal dementia.

Irwin DJ, McMillan CT, Xie SX, Rascovsky K, Van Deerlin VM, Coslett HB, Hamilton R, Aguirre GK, Lee EB, Lee VMY, Trojanowski JQ, Grossman M.

Brain. 2018 Jan 1;141(1):288-301. doi: 10.1093/brain/awx319.

25.

Neocortical origin and progression of gray matter atrophy in nonamnestic Alzheimer's disease.

Phillips JS, Da Re F, Dratch L, Xie SX, Irwin DJ, McMillan CT, Vaishnavi SN, Ferrarese C, Lee EB, Shaw LM, Trojanowski JQ, Wolk DA, Grossman M.

Neurobiol Aging. 2018 Mar;63:75-87. doi: 10.1016/j.neurobiolaging.2017.11.008. Epub 2017 Nov 21.

26.

Tau PET imaging predicts cognition in atypical variants of Alzheimer's disease.

Phillips JS, Das SR, McMillan CT, Irwin DJ, Roll EE, Da Re F, Nasrallah IM, Wolk DA, Grossman M.

Hum Brain Mapp. 2018 Feb;39(2):691-708. doi: 10.1002/hbm.23874. Epub 2017 Nov 6.

27.

18 F-flortaucipir tau positron emission tomography distinguishes established progressive supranuclear palsy from controls and Parkinson disease: A multicenter study.

Schonhaut DR, McMillan CT, Spina S, Dickerson BC, Siderowf A, Devous MD Sr, Tsai R, Winer J, Russell DS, Litvan I, Roberson ED, Seeley WW, Grinberg LT, Kramer JH, Miller BL, Pressman P, Nasrallah I, Baker SL, Gomperts SN, Johnson KA, Grossman M, Jagust WJ, Boxer AL, Rabinovici GD.

Ann Neurol. 2017 Oct;82(4):622-634. doi: 10.1002/ana.25060.

28.

Brain network efficiency is influenced by the pathologic source of corticobasal syndrome.

Medaglia JD, Huang W, Segarra S, Olm C, Gee J, Grossman M, Ribeiro A, McMillan CT, Bassett DS.

Neurology. 2017 Sep 26;89(13):1373-1381. doi: 10.1212/WNL.0000000000004324. Epub 2017 Aug 4.

29.

18F-Flortaucipir PET/MRI Correlations in Nonamnestic and Amnestic Variants of Alzheimer Disease.

Nasrallah IM, Chen YJ, Hsieh MK, Phillips JS, Ternes K, Stockbower GE, Sheline Y, McMillan CT, Grossman M, Wolk DA.

J Nucl Med. 2018 Feb;59(2):299-306. doi: 10.2967/jnumed.117.194282. Epub 2017 Jul 26. Erratum in: J Nucl Med. 2019 May;60(5):709.

30.

Ante mortem cerebrospinal fluid tau levels correlate with postmortem tau pathology in frontotemporal lobar degeneration.

Irwin DJ, Lleó A, Xie SX, McMillan CT, Wolk DA, Lee EB, Van Deerlin VM, Shaw LM, Trojanowski JQ, Grossman M.

Ann Neurol. 2017 Aug;82(2):247-258. doi: 10.1002/ana.24996. Epub 2017 Aug 19.

31.

Neural Correlates of Verbal Episodic Memory and Lexical Retrieval in Logopenic Variant Primary Progressive Aphasia.

Win KT, Pluta J, Yushkevich P, Irwin DJ, McMillan CT, Rascovsky K, Wolk D, Grossman M.

Front Neurosci. 2017 Jun 14;11:330. doi: 10.3389/fnins.2017.00330. eCollection 2017.

32.

Clinical marker for Alzheimer disease pathology in logopenic primary progressive aphasia.

Giannini LAA, Irwin DJ, McMillan CT, Ash S, Rascovsky K, Wolk DA, Van Deerlin VM, Lee EB, Trojanowski JQ, Grossman M.

Neurology. 2017 Jun 13;88(24):2276-2284. doi: 10.1212/WNL.0000000000004034. Epub 2017 May 17.

33.

Author response: Cognitive reserve in frontotemporal degeneration: Neuroanatomic and neuropsychological evidence.

Placek K, Massimo L, Grossman M, McMillan CT.

Neurology. 2017 Apr 18;88(16):1590-1591. doi: 10.1212/WNL.0000000000003856. No abstract available.

PMID:
28416618
34.

Cognitive decline associated with pathological burden in primary age-related tauopathy.

Jefferson-George KS, Wolk DA, Lee EB, McMillan CT.

Alzheimers Dement. 2017 Sep;13(9):1048-1053. doi: 10.1016/j.jalz.2017.01.028. Epub 2017 Mar 16.

35.

Narrative Organization Deficit in Lewy Body Disorders Is Related to Alzheimer Pathology.

Grossman M, Irwin DJ, Jester C, Halpin A, Ash S, Rascovsky K, Weintraub D, McMillan CT.

Front Neurosci. 2017 Feb 8;11:53. doi: 10.3389/fnins.2017.00053. eCollection 2017.

36.

Decision-Making Deficits Associated with Amyloidosis in Lewy Body Disorders.

Spotorno N, McMillan CT, Irwin DJ, Clark R, Lee EB, Trojanowski JQ, Weintraub D, Grossman M.

Front Hum Neurosci. 2017 Jan 11;10:693. doi: 10.3389/fnhum.2016.00693. eCollection 2016.

37.

Multimodal evaluation demonstrates in vivo 18F-AV-1451 uptake in autopsy-confirmed corticobasal degeneration.

McMillan CT, Irwin DJ, Nasrallah I, Phillips JS, Spindler M, Rascovsky K, Ternes K, Jester C, Wolk DA, Kwong LK, Lee VM, Lee EB, Trojanowski JQ, Grossman M.

Acta Neuropathol. 2016 Dec;132(6):935-937. Epub 2016 Nov 4. No abstract available.

38.

Cognitive reserve in frontotemporal degeneration: Neuroanatomic and neuropsychological evidence.

Placek K, Massimo L, Olm C, Ternes K, Firn K, Van Deerlin V, Lee EB, Trojanowski JQ, Lee VM, Irwin D, Grossman M, McMillan CT.

Neurology. 2016 Oct 25;87(17):1813-1819. Epub 2016 Sep 28.

39.

Multimodal imaging evidence of pathology-mediated disease distribution in corticobasal syndrome.

McMillan CT, Boyd C, Gross RG, Weinstein J, Firn K, Toledo JB, Rascovsky K, Shaw L, Wolk DA, Irwin DJ, Lee EB, Trojanowski JQ, Grossman M.

Neurology. 2016 Sep 20;87(12):1227-34. doi: 10.1212/WNL.0000000000003119. Epub 2016 Aug 19.

40.

White matter hyperintensities are more highly associated with preclinical Alzheimer's disease than imaging and cognitive markers of neurodegeneration.

Kandel BM, Avants BB, Gee JC, McMillan CT, Erus G, Doshi J, Davatzikos C, Wolk DA.

Alzheimers Dement (Amst). 2016 Apr 7;4:18-27. doi: 10.1016/j.dadm.2016.03.001. eCollection 2016.

41.

Category learning in Alzheimer's disease and normal cognitive aging depends on initial experience of feature variability.

Phillips JS, McMillan CT, Smith EE, Grossman M.

Neuropsychologia. 2017 Apr;98:98-110. doi: 10.1016/j.neuropsychologia.2016.07.003. Epub 2016 Jul 6.

42.

Arterial spin labeling perfusion predicts longitudinal decline in semantic variant primary progressive aphasia.

Olm CA, Kandel BM, Avants BB, Detre JA, Gee JC, Grossman M, McMillan CT.

J Neurol. 2016 Oct;263(10):1927-38. doi: 10.1007/s00415-016-8221-1. Epub 2016 Jul 5.

43.

Dissociation of quantifiers and object nouns in speech in focal neurodegenerative disease.

Ash S, Ternes K, Bisbing T, Min NE, Moran E, York C, McMillan CT, Irwin DJ, Grossman M.

Neuropsychologia. 2016 Aug;89:141-152. doi: 10.1016/j.neuropsychologia.2016.06.013. Epub 2016 Jun 11.

44.

Presence of cerebral amyloid modulates phenotype and pattern of neurodegeneration in early Parkinson's disease.

McMillan CT, Wolk DA.

J Neurol Neurosurg Psychiatry. 2016 Oct;87(10):1112-22. doi: 10.1136/jnnp-2015-312690. Epub 2016 Jun 9.

45.

Genetic and environmental factors associated with delirium severity in older adults with dementia.

Massimo L, Munoz E, Hill N, Mogle J, Mulhall P, McMillan CT, Clare L, Vandenbergh D, Fick D, Kolanowski A.

Int J Geriatr Psychiatry. 2017 May;32(5):574-581. doi: 10.1002/gps.4496. Epub 2016 Apr 27.

46.

Neurodegenerative disease: MRI biomarkers - a precision medicine tool in neurology?

McMillan CT.

Nat Rev Neurol. 2016 Jun;12(6):323-4. doi: 10.1038/nrneurol.2016.51. Epub 2016 Apr 15. No abstract available.

47.

Apathy in Frontotemporal Degeneration: Neuroanatomical Evidence of Impaired Goal-directed Behavior.

Massimo L, Powers JP, Evans LK, McMillan CT, Rascovsky K, Eslinger P, Ersek M, Irwin DJ, Grossman M.

Front Hum Neurosci. 2015 Nov 10;9:611. doi: 10.3389/fnhum.2015.00611. eCollection 2015.

48.

Deep clinical and neuropathological phenotyping of Pick disease.

Irwin DJ, Brettschneider J, McMillan CT, Cooper F, Olm C, Arnold SE, Van Deerlin VM, Seeley WW, Miller BL, Lee EB, Lee VM, Grossman M, Trojanowski JQ.

Ann Neurol. 2016 Feb;79(2):272-87. doi: 10.1002/ana.24559. Epub 2015 Dec 25.

49.

Processing ambiguity in a linguistic context: decision-making difficulties in non-aphasic patients with behavioral variant frontotemporal degeneration.

Spotorno N, Healey M, McMillan CT, Rascovsky K, Irwin DJ, Clark R, Grossman M.

Front Hum Neurosci. 2015 Oct 27;9:583. doi: 10.3389/fnhum.2015.00583. eCollection 2015.

50.

Semi-Automated Digital Image Analysis of Pick's Disease and TDP-43 Proteinopathy.

Irwin DJ, Byrne MD, McMillan CT, Cooper F, Arnold SE, Lee EB, Van Deerlin VM, Xie SX, Lee VM, Grossman M, Trojanowski JQ.

J Histochem Cytochem. 2016 Jan;64(1):54-66. doi: 10.1369/0022155415614303. Epub 2015 Nov 4.

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