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Items: 1 to 50 of 81

1.

Longitudinal structural gray matter and white matter MRI changes in presymptomatic progranulin mutation carriers.

Olm CA, McMillan CT, Irwin DJ, Van Deerlin VM, Cook PA, Gee JC, Grossman M.

Neuroimage Clin. 2018 May 15;19:497-506. doi: 10.1016/j.nicl.2018.05.017. eCollection 2018.

2.

Neurodegenerative disease concomitant proteinopathies are prevalent, age-related and APOE4-associated.

Robinson JL, Lee EB, Xie SX, Rennert L, Suh E, Bredenberg C, Caswell C, Van Deerlin VM, Yan N, Yousef A, Hurtig HI, Siderowf A, Grossman M, McMillan CT, Miller B, Duda JE, Irwin DJ, Wolk D, Elman L, McCluskey L, Chen-Plotkin A, Weintraub D, Arnold SE, Brettschneider J, Lee VM, Trojanowski JQ.

Brain. 2018 Jul 1;141(7):2181-2193. doi: 10.1093/brain/awy146.

PMID:
29878075
3.

Perfusion alterations converge with patterns of pathological spread in transactive response DNA-binding protein 43 proteinopathies.

Ferraro PM, Jester C, Olm CA, Placek K, Agosta F, Elman L, McCluskey L, Irwin DJ, Detre JA, Filippi M, Grossman M, McMillan CT.

Neurobiol Aging. 2018 Aug;68:85-92. doi: 10.1016/j.neurobiolaging.2018.04.008. Epub 2018 Apr 17.

PMID:
29751289
4.

Amyloid "accumulators": The next generation of candidates for amyloid-targeted clinical trials?

McMillan CT, Chételat G.

Neurology. 2018 Apr 24;90(17):759-760. doi: 10.1212/WNL.0000000000005362. Epub 2018 Mar 23. No abstract available.

PMID:
29572279
5.

A 2-Step Cerebrospinal Algorithm for the Selection of Frontotemporal Lobar Degeneration Subtypes.

Lleó A, Irwin DJ, Illán-Gala I, McMillan CT, Wolk DA, Lee EB, Van Deerlin VM, Shaw LM, Trojanowski JQ, Grossman M.

JAMA Neurol. 2018 Jun 1;75(6):738-745. doi: 10.1001/jamaneurol.2018.0118.

PMID:
29554190
6.

Occupational attainment influences longitudinal decline in behavioral variant frontotemporal degeneration.

Massimo L, Xie SX, Rennert L, Fick DM, Halpin A, Placek K, Williams A, Rascovsky K, Irwin DJ, Grossman M, McMillan CT.

Brain Imaging Behav. 2018 Mar 14. doi: 10.1007/s11682-018-9852-x. [Epub ahead of print]

PMID:
29542053
7.

CSF tau and β-amyloid predict cerebral synucleinopathy in autopsied Lewy body disorders.

Irwin DJ, Xie SX, Coughlin D, Nevler N, Akhtar RS, McMillan CT, Lee EB, Wolk DA, Weintraub D, Chen-Plotkin A, Duda JE, Spindler M, Siderowf A, Hurtig HI, Shaw LM, Grossman M, Trojanowski JQ.

Neurology. 2018 Mar 20;90(12):e1038-e1046. doi: 10.1212/WNL.0000000000005166. Epub 2018 Feb 21.

PMID:
29467305
8.

Flortaucipir imaging of MAPT: Mutations emphasize challenges for tau-targeted trials.

McMillan CT, Huey ED.

Neurology. 2018 Mar 13;90(11):495-496. doi: 10.1212/WNL.0000000000005112. Epub 2018 Feb 9. No abstract available.

PMID:
29440565
9.

Asymmetry of post-mortem neuropathology in behavioural-variant frontotemporal dementia.

Irwin DJ, McMillan CT, Xie SX, Rascovsky K, Van Deerlin VM, Coslett HB, Hamilton R, Aguirre GK, Lee EB, Lee VMY, Trojanowski JQ, Grossman M.

Brain. 2018 Jan 1;141(1):288-301. doi: 10.1093/brain/awx319.

PMID:
29228211
10.

Neocortical origin and progression of gray matter atrophy in nonamnestic Alzheimer's disease.

Phillips JS, Da Re F, Dratch L, Xie SX, Irwin DJ, McMillan CT, Vaishnavi SN, Ferrarese C, Lee EB, Shaw LM, Trojanowski JQ, Wolk DA, Grossman M.

Neurobiol Aging. 2018 Mar;63:75-87. doi: 10.1016/j.neurobiolaging.2017.11.008. Epub 2017 Nov 21.

PMID:
29223682
11.

Tau PET imaging predicts cognition in atypical variants of Alzheimer's disease.

Phillips JS, Das SR, McMillan CT, Irwin DJ, Roll EE, Da Re F, Nasrallah IM, Wolk DA, Grossman M.

Hum Brain Mapp. 2018 Feb;39(2):691-708. doi: 10.1002/hbm.23874. Epub 2017 Nov 6.

PMID:
29105977
12.

18 F-flortaucipir tau positron emission tomography distinguishes established progressive supranuclear palsy from controls and Parkinson disease: A multicenter study.

Schonhaut DR, McMillan CT, Spina S, Dickerson BC, Siderowf A, Devous MD Sr, Tsai R, Winer J, Russell DS, Litvan I, Roberson ED, Seeley WW, Grinberg LT, Kramer JH, Miller BL, Pressman P, Nasrallah I, Baker SL, Gomperts SN, Johnson KA, Grossman M, Jagust WJ, Boxer AL, Rabinovici GD.

Ann Neurol. 2017 Oct;82(4):622-634. doi: 10.1002/ana.25060.

13.

Brain network efficiency is influenced by the pathologic source of corticobasal syndrome.

Medaglia JD, Huang W, Segarra S, Olm C, Gee J, Grossman M, Ribeiro A, McMillan CT, Bassett DS.

Neurology. 2017 Sep 26;89(13):1373-1381. doi: 10.1212/WNL.0000000000004324. Epub 2017 Aug 4.

14.

18F-Flortaucipir PET/MRI Correlations in Nonamnestic and Amnestic Variants of Alzheimer Disease.

Nasrallah IM, Chen YJ, Hsieh MK, Phillips JS, Ternes K, Stockbower GE, Sheline Y, McMillan CT, Grossman M, Wolk DA.

J Nucl Med. 2018 Feb;59(2):299-306. doi: 10.2967/jnumed.117.194282. Epub 2017 Jul 26.

PMID:
28747523
15.

Ante mortem cerebrospinal fluid tau levels correlate with postmortem tau pathology in frontotemporal lobar degeneration.

Irwin DJ, Lleó A, Xie SX, McMillan CT, Wolk DA, Lee EB, Van Deerlin VM, Shaw LM, Trojanowski JQ, Grossman M.

Ann Neurol. 2017 Aug;82(2):247-258. doi: 10.1002/ana.24996. Epub 2017 Aug 19.

PMID:
28719018
16.

Neural Correlates of Verbal Episodic Memory and Lexical Retrieval in Logopenic Variant Primary Progressive Aphasia.

Win KT, Pluta J, Yushkevich P, Irwin DJ, McMillan CT, Rascovsky K, Wolk D, Grossman M.

Front Neurosci. 2017 Jun 14;11:330. doi: 10.3389/fnins.2017.00330. eCollection 2017.

17.

Clinical marker for Alzheimer disease pathology in logopenic primary progressive aphasia.

Giannini LAA, Irwin DJ, McMillan CT, Ash S, Rascovsky K, Wolk DA, Van Deerlin VM, Lee EB, Trojanowski JQ, Grossman M.

Neurology. 2017 Jun 13;88(24):2276-2284. doi: 10.1212/WNL.0000000000004034. Epub 2017 May 17.

18.

Author response: Cognitive reserve in frontotemporal degeneration: Neuroanatomic and neuropsychological evidence.

Placek K, Massimo L, Grossman M, McMillan CT.

Neurology. 2017 Apr 18;88(16):1590-1591. doi: 10.1212/WNL.0000000000003856. No abstract available.

PMID:
28416618
19.

Cognitive decline associated with pathological burden in primary age-related tauopathy.

Jefferson-George KS, Wolk DA, Lee EB, McMillan CT.

Alzheimers Dement. 2017 Sep;13(9):1048-1053. doi: 10.1016/j.jalz.2017.01.028. Epub 2017 Mar 16.

PMID:
28322204
20.

Narrative Organization Deficit in Lewy Body Disorders Is Related to Alzheimer Pathology.

Grossman M, Irwin DJ, Jester C, Halpin A, Ash S, Rascovsky K, Weintraub D, McMillan CT.

Front Neurosci. 2017 Feb 8;11:53. doi: 10.3389/fnins.2017.00053. eCollection 2017.

21.

Decision-Making Deficits Associated with Amyloidosis in Lewy Body Disorders.

Spotorno N, McMillan CT, Irwin DJ, Clark R, Lee EB, Trojanowski JQ, Weintraub D, Grossman M.

Front Hum Neurosci. 2017 Jan 11;10:693. doi: 10.3389/fnhum.2016.00693. eCollection 2016.

22.

Multimodal evaluation demonstrates in vivo 18F-AV-1451 uptake in autopsy-confirmed corticobasal degeneration.

McMillan CT, Irwin DJ, Nasrallah I, Phillips JS, Spindler M, Rascovsky K, Ternes K, Jester C, Wolk DA, Kwong LK, Lee VM, Lee EB, Trojanowski JQ, Grossman M.

Acta Neuropathol. 2016 Dec;132(6):935-937. Epub 2016 Nov 4. No abstract available.

23.

Cognitive reserve in frontotemporal degeneration: Neuroanatomic and neuropsychological evidence.

Placek K, Massimo L, Olm C, Ternes K, Firn K, Van Deerlin V, Lee EB, Trojanowski JQ, Lee VM, Irwin D, Grossman M, McMillan CT.

Neurology. 2016 Oct 25;87(17):1813-1819. Epub 2016 Sep 28.

24.

Multimodal imaging evidence of pathology-mediated disease distribution in corticobasal syndrome.

McMillan CT, Boyd C, Gross RG, Weinstein J, Firn K, Toledo JB, Rascovsky K, Shaw L, Wolk DA, Irwin DJ, Lee EB, Trojanowski JQ, Grossman M.

Neurology. 2016 Sep 20;87(12):1227-34. doi: 10.1212/WNL.0000000000003119. Epub 2016 Aug 19.

25.

White matter hyperintensities are more highly associated with preclinical Alzheimer's disease than imaging and cognitive markers of neurodegeneration.

Kandel BM, Avants BB, Gee JC, McMillan CT, Erus G, Doshi J, Davatzikos C, Wolk DA.

Alzheimers Dement (Amst). 2016 Apr 7;4:18-27. doi: 10.1016/j.dadm.2016.03.001. eCollection 2016.

26.

Category learning in Alzheimer's disease and normal cognitive aging depends on initial experience of feature variability.

Phillips JS, McMillan CT, Smith EE, Grossman M.

Neuropsychologia. 2017 Apr;98:98-110. doi: 10.1016/j.neuropsychologia.2016.07.003. Epub 2016 Jul 6.

27.

Arterial spin labeling perfusion predicts longitudinal decline in semantic variant primary progressive aphasia.

Olm CA, Kandel BM, Avants BB, Detre JA, Gee JC, Grossman M, McMillan CT.

J Neurol. 2016 Oct;263(10):1927-38. doi: 10.1007/s00415-016-8221-1. Epub 2016 Jul 5.

28.

Dissociation of quantifiers and object nouns in speech in focal neurodegenerative disease.

Ash S, Ternes K, Bisbing T, Min NE, Moran E, York C, McMillan CT, Irwin DJ, Grossman M.

Neuropsychologia. 2016 Aug;89:141-152. doi: 10.1016/j.neuropsychologia.2016.06.013. Epub 2016 Jun 11.

29.

Presence of cerebral amyloid modulates phenotype and pattern of neurodegeneration in early Parkinson's disease.

McMillan CT, Wolk DA.

J Neurol Neurosurg Psychiatry. 2016 Oct;87(10):1112-22. doi: 10.1136/jnnp-2015-312690. Epub 2016 Jun 9.

30.

Genetic and environmental factors associated with delirium severity in older adults with dementia.

Massimo L, Munoz E, Hill N, Mogle J, Mulhall P, McMillan CT, Clare L, Vandenbergh D, Fick D, Kolanowski A.

Int J Geriatr Psychiatry. 2017 May;32(5):574-581. doi: 10.1002/gps.4496. Epub 2016 Apr 27.

31.

Neurodegenerative disease: MRI biomarkers - a precision medicine tool in neurology?

McMillan CT.

Nat Rev Neurol. 2016 Jun;12(6):323-4. doi: 10.1038/nrneurol.2016.51. Epub 2016 Apr 15. No abstract available.

32.

Apathy in Frontotemporal Degeneration: Neuroanatomical Evidence of Impaired Goal-directed Behavior.

Massimo L, Powers JP, Evans LK, McMillan CT, Rascovsky K, Eslinger P, Ersek M, Irwin DJ, Grossman M.

Front Hum Neurosci. 2015 Nov 10;9:611. doi: 10.3389/fnhum.2015.00611. eCollection 2015.

33.

Deep clinical and neuropathological phenotyping of Pick disease.

Irwin DJ, Brettschneider J, McMillan CT, Cooper F, Olm C, Arnold SE, Van Deerlin VM, Seeley WW, Miller BL, Lee EB, Lee VM, Grossman M, Trojanowski JQ.

Ann Neurol. 2016 Feb;79(2):272-87. doi: 10.1002/ana.24559. Epub 2015 Dec 25.

34.

Processing ambiguity in a linguistic context: decision-making difficulties in non-aphasic patients with behavioral variant frontotemporal degeneration.

Spotorno N, Healey M, McMillan CT, Rascovsky K, Irwin DJ, Clark R, Grossman M.

Front Hum Neurosci. 2015 Oct 27;9:583. doi: 10.3389/fnhum.2015.00583. eCollection 2015.

35.

Semi-Automated Digital Image Analysis of Pick's Disease and TDP-43 Proteinopathy.

Irwin DJ, Byrne MD, McMillan CT, Cooper F, Arnold SE, Lee EB, Van Deerlin VM, Xie SX, Lee VM, Grossman M, Trojanowski JQ.

J Histochem Cytochem. 2016 Jan;64(1):54-66. doi: 10.1369/0022155415614303. Epub 2015 Nov 4.

36.

How the brain learns how few are "many": An fMRI study of the flexibility of quantifier semantics.

Heim S, McMillan CT, Clark R, Baehr L, Ternes K, Olm C, Min NE, Grossman M.

Neuroimage. 2016 Jan 15;125:45-52. doi: 10.1016/j.neuroimage.2015.10.035. Epub 2015 Oct 17.

37.

Beyond words: Pragmatic inference in behavioral variant of frontotemporal degeneration.

Spotorno N, McMillan CT, Rascovsky K, Irwin DJ, Clark R, Grossman M.

Neuropsychologia. 2015 Aug;75:556-64. doi: 10.1016/j.neuropsychologia.2015.07.002. Epub 2015 Jul 4.

38.

Estimating frontal and parietal involvement in cognitive estimation: a study of focal neurodegenerative diseases.

Bisbing TA, Olm CA, McMillan CT, Rascovsky K, Baehr L, Ternes K, Irwin DJ, Clark R, Grossman M.

Front Hum Neurosci. 2015 Jun 4;9:317. doi: 10.3389/fnhum.2015.00317. eCollection 2015.

39.

Semi-automated quantification of C9orf72 expansion size reveals inverse correlation between hexanucleotide repeat number and disease duration in frontotemporal degeneration.

Suh E, Lee EB, Neal D, Wood EM, Toledo JB, Rennert L, Irwin DJ, McMillan CT, Krock B, Elman LB, McCluskey LF, Grossman M, Xie SX, Trojanowski JQ, Van Deerlin VM.

Acta Neuropathol. 2015 Sep;130(3):363-72. doi: 10.1007/s00401-015-1445-9. Epub 2015 May 29.

40.

If so many are "few," how few are "many"?

Heim S, McMillan CT, Clark R, Golob S, Min NE, Olm C, Powers J, Grossman M.

Front Psychol. 2015 Apr 17;6:441. doi: 10.3389/fpsyg.2015.00441. eCollection 2015.

41.

Occupational attainment influences survival in autopsy-confirmed frontotemporal degeneration.

Massimo L, Zee J, Xie SX, McMillan CT, Rascovsky K, Irwin DJ, Kolanowski A, Grossman M.

Neurology. 2015 May 19;84(20):2070-5. doi: 10.1212/WNL.0000000000001595. Epub 2015 Apr 22.

42.

Impaired cognitive flexibility in amyotrophic lateral sclerosis.

Evans J, Olm C, McCluskey L, Elman L, Boller A, Moran E, Rascovsky K, Bisbing T, McMillan CT, Grossman M.

Cogn Behav Neurol. 2015 Mar;28(1):17-26. doi: 10.1097/WNN.0000000000000049.

43.

C9orf72 promoter hypermethylation is neuroprotective: Neuroimaging and neuropathologic evidence.

McMillan CT, Russ J, Wood EM, Irwin DJ, Grossman M, McCluskey L, Elman L, Van Deerlin V, Lee EB.

Neurology. 2015 Apr 21;84(16):1622-30. doi: 10.1212/WNL.0000000000001495. Epub 2015 Mar 20.

44.

Getting on the same page: the neural basis for social coordination deficits in behavioral variant frontotemporal degeneration.

Healey ML, McMillan CT, Golob S, Spotorno N, Rascovsky K, Irwin DJ, Clark R, Grossman M.

Neuropsychologia. 2015 Mar;69:56-66. doi: 10.1016/j.neuropsychologia.2015.01.028. Epub 2015 Jan 22.

45.

Frontotemporal lobar degeneration: defining phenotypic diversity through personalized medicine.

Irwin DJ, Cairns NJ, Grossman M, McMillan CT, Lee EB, Van Deerlin VM, Lee VM, Trojanowski JQ.

Acta Neuropathol. 2015 Apr;129(4):469-91. doi: 10.1007/s00401-014-1380-1. Epub 2014 Dec 31.

46.

White matter disease contributes to apathy and disinhibition in behavioral variant frontotemporal dementia.

Powers JP, Massimo L, McMillan CT, Yushkevich PA, Zhang H, Gee JC, Grossman M.

Cogn Behav Neurol. 2014 Dec;27(4):206-14. doi: 10.1097/WNN.0000000000000044.

47.

Deficits in sentence expression in amyotrophic lateral sclerosis.

Ash S, Olm C, McMillan CT, Boller A, Irwin DJ, McCluskey L, Elman L, Grossman M.

Amyotroph Lateral Scler Frontotemporal Degener. 2015 Mar;16(1-2):31-9. doi: 10.3109/21678421.2014.974617. Epub 2014 Dec 8.

48.

Hypermethylation of repeat expanded C9orf72 is a clinical and molecular disease modifier.

Russ J, Liu EY, Wu K, Neal D, Suh E, Irwin DJ, McMillan CT, Harms MB, Cairns NJ, Wood EM, Xie SX, Elman L, McCluskey L, Grossman M, Van Deerlin VM, Lee EB.

Acta Neuropathol. 2015 Jan;129(1):39-52. doi: 10.1007/s00401-014-1365-0. Epub 2014 Nov 12.

49.

Counting or chunking? Mathematical and heuristic abilities in patients with corticobasal syndrome and posterior cortical atrophy.

Spotorno N, McMillan CT, Powers JP, Clark R, Grossman M.

Neuropsychologia. 2014 Nov;64:176-83. doi: 10.1016/j.neuropsychologia.2014.09.030. Epub 2014 Sep 30.

50.

The relative contributions of frontal and parietal cortex for generalized quantifier comprehension.

Olm CA, McMillan CT, Spotorno N, Clark R, Grossman M.

Front Hum Neurosci. 2014 Aug 7;8:610. doi: 10.3389/fnhum.2014.00610. eCollection 2014.

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