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Public health within local government, six years on.

Fell G, McManus J.

BMJ. 2020 Feb 19;368:m572. doi: 10.1136/bmj.m572. No abstract available.


Site-Selective C-H Alkylation of Piperazine Substrates via Organic Photoredox Catalysis.

McManus JB, Onuska NPR, Jeffreys MS, Goodwin NC, Nicewicz DA.

Org Lett. 2020 Jan 17;22(2):679-683. doi: 10.1021/acs.orglett.9b04456. Epub 2020 Jan 6.


Structure-dependent retention of steroid hormones by common laboratory materials.

McManus JM, Sharifi N.

J Steroid Biochem Mol Biol. 2019 Dec 26;198:105572. doi: 10.1016/j.jsbmb.2019.105572. [Epub ahead of print]


Rapid and Precise Analysis of Carbon Dioxide Clumped Isotopic Composition by Tunable Infrared Laser Differential Spectroscopy.

Wang Z, Nelson DD, Dettman DL, McManus JB, Quade J, Huntington KW, Schauer AJ, Sakai S.

Anal Chem. 2020 Jan 21;92(2):2034-2042. doi: 10.1021/acs.analchem.9b04466. Epub 2020 Jan 7.


Anticoagulant Reversal Strategies in the Emergency Department Setting: Recommendations of a Multidisciplinary Expert Panel.

Baugh CW, Levine M, Cornutt D, Wilson JW, Kwun R, Mahan CE, Pollack CV Jr, Marcolini EG, Milling TJ Jr, Peacock WF, Rosovsky RP, Wu F, Sarode R, Spyropoulos AC, Villines TC, Woods TD, McManus J, Williams J.

Ann Emerg Med. 2019 Nov 13. pii: S0196-0644(19)31181-3. doi: 10.1016/j.annemergmed.2019.09.001. [Epub ahead of print]


Precise Measurements of 12CH2D2 by Tunable Infrared Laser Direct Absorption Spectroscopy.

Gonzalez Y, Nelson DD, Shorter JH, McManus JB, Dyroff C, Formolo M, Wang DT, Western CM, Ono S.

Anal Chem. 2019 Dec 3;91(23):14967-14974. doi: 10.1021/acs.analchem.9b03412. Epub 2019 Nov 12.


Rapid and structure-specific cellular uptake of selected steroids.

McManus JM, Bohn K, Alyamani M, Chung YM, Klein EA, Sharifi N.

PLoS One. 2019 Oct 17;14(10):e0224081. doi: 10.1371/journal.pone.0224081. eCollection 2019.


Using Schematic Models to Understand the Microscopic Basis for Inverted Solubility in γD-Crystallin.

Altan I, Khan AR, James S, Quinn MK, McManus JJ, Charbonneau P.

J Phys Chem B. 2019 Nov 27;123(47):10061-10072. doi: 10.1021/acs.jpcb.9b07774. Epub 2019 Oct 10.


Observation of Rainbows in the Rotationally Inelastic Scattering of NO with CH4.

Wang XD, Robertson PA, Cascarini FJJ, Quinn MS, McManus JW, Orr-Ewing AJ.

J Phys Chem A. 2019 Sep 12;123(36):7758-7767. doi: 10.1021/acs.jpca.9b06806. Epub 2019 Sep 4.


Temperature-Dependent Interactions Explain Normal and Inverted Solubility in a γD-Crystallin Mutant.

Khan AR, James S, Quinn MK, Altan I, Charbonneau P, McManus JJ.

Biophys J. 2019 Sep 3;117(5):930-937. doi: 10.1016/j.bpj.2019.07.019. Epub 2019 Jul 19.


Dairy cow feeding system alters the characteristics of low-heat skim milk powder and processability of reconstituted skim milk.

Gulati A, Hennessy D, O'Donovan M, McManus JJ, Fenelon MA, Guinee TP.

J Dairy Sci. 2019 Oct;102(10):8630-8647. doi: 10.3168/jds.2018-15884. Epub 2019 Aug 1.


Fluorescence Correlation Spectroscopy for Particle Sizing in Highly Concentrated Protein Solutions.

Mittag JJ, Jacobs MR, McManus JJ.

Methods Mol Biol. 2019;2039:157-171. doi: 10.1007/978-1-4939-9678-0_12.


Differential Scanning Calorimetry to Quantify Heat-Induced Aggregation in Concentrated Protein Solutions.

Jacobs MR, Grace M, Blumlein A, McManus JJ.

Methods Mol Biol. 2019;2039:117-129. doi: 10.1007/978-1-4939-9678-0_9.


Ultrafast Carrier Dynamics and Bandgap Renormalization in Layered PtSe2.

Wang G, Wang K, McEvoy N, Bai Z, Cullen CP, Murphy CN, McManus JB, Magan JJ, Smith CM, Duesberg GS, Kaminer I, Wang J, Blau WJ.

Small. 2019 Aug;15(34):e1902728. doi: 10.1002/smll.201902728. Epub 2019 Jul 5.


More efficient North Atlantic carbon pump during the Last Glacial Maximum.

Yu J, Menviel L, Jin ZD, Thornalley DJR, Foster GL, Rohling EJ, McCave IN, McManus JF, Dai Y, Ren H, He F, Zhang F, Chen PJ, Roberts AP.

Nat Commun. 2019 May 15;10(1):2170. doi: 10.1038/s41467-019-10028-z.


Chemical Modification Alters Protein-Protein Interactions and Can Lead to Lower Protein Solubility.

Quinn MK, James S, McManus JJ.

J Phys Chem B. 2019 May 23;123(20):4373-4379. doi: 10.1021/acs.jpcb.9b02368. Epub 2019 May 13.


Convergent evolution of hetero-oligomeric cellulose synthesis complexes in mosses and seed plants.

Li X, Speicher TL, Dees DCT, Mansoori N, McManus JB, Tien M, Trindade LM, Wallace IS, Roberts AW.

Plant J. 2019 Sep;99(5):862-876. doi: 10.1111/tpj.14366. Epub 2019 May 25.


Successful and unsuccessful attempts to swallow in a reduced Aplysia preparation regulate feeding responses and produce memory at different neural sites.

McManus JM, Chiel HJ, Susswein AJ.

Learn Mem. 2019 Apr 16;26(5):151-165. doi: 10.1101/lm.048983.118. Print 2019 May.


Simulations of Cellulose Synthesis Initiation and Termination in Bacteria.

Yang H, McManus J, Oehme D, Singh A, Yingling YG, Tien M, Kubicki JD.

J Phys Chem B. 2019 May 2;123(17):3699-3705. doi: 10.1021/acs.jpcb.9b02433. Epub 2019 Apr 24.


Well leg compartment syndrome in trauma surgery - femoral shaft fracture treated by femoral intramedullary nailing in the hemilithotomy position: case series and review of the literature.

Brouze IF, Steinmetz S, McManus J, Borens O.

Ther Clin Risk Manag. 2019 Feb 8;15:241-250. doi: 10.2147/TCRM.S177530. eCollection 2019.


Can child-focused sanitation and nutrition programming improve health practices and outcomes? Evidence from a randomised controlled trial in Kitui County, Kenya.

Gimaiyo G, McManus J, Yarri M, Singh S, Trevett A, Moloney G, Robins A, Lehmann L.

BMJ Glob Health. 2019 Jan 5;4(1):e000973. doi: 10.1136/bmjgh-2018-000973. eCollection 2019.


Business not as usual: how multisectoral collaboration can promote transformative change for health and sustainable development.

Kuruvilla S, Hinton R, Boerma T, Bunney R, Casamitjana N, Cortez R, Fracassi P, Franz-Vasdeki J, Helldén D, McManus J, Papp S, Rasanathan K, Requejo J, Silver KL, Tenhoope-Bender P, Velleman Y, Wegner MN, Armstrong CE, Barnett S, Blauvelt C, Buang SN, Bury L, Callahan EA, Das JK, Gurnani V, Kaba MW, Milman HM, Murray J, Renner I, Roche ML, Saint V, Simpson S, Subedar H, Ukhova D, Velásquez CN, Young P, Graham W; PMNCH Multisectoral Collaboration Study Group.

BMJ. 2018 Dec 7;363:k4771. doi: 10.1136/bmj.k4771. No abstract available.


Characteristics and Diversity of ACGME Accredited Emergency Medical Services Fellowship Programs.

March JA, Adams JL, Portela RC, Taylor SE, McManus JG.

Prehosp Emerg Care. 2019 Jul-Aug;23(4):551-559. doi: 10.1080/10903127.2018.1544327. Epub 2018 Dec 7.


Enhanced climate instability in the North Atlantic and southern Europe during the Last Interglacial.

Tzedakis PC, Drysdale RN, Margari V, Skinner LC, Menviel L, Rhodes RH, Taschetto AS, Hodell DA, Crowhurst SJ, Hellstrom JC, Fallick AE, Grimalt JO, McManus JF, Martrat B, Mokeddem Z, Parrenin F, Regattieri E, Roe K, Zanchetta G.

Nat Commun. 2018 Oct 12;9(1):4235. doi: 10.1038/s41467-018-06683-3.


Pilot-scale formation of whey protein aggregates determine the stability of heat-treated whey protein solutions-Effect of pH and protein concentration.

Buggy AK, McManus JJ, Brodkorb A, Hogan SA, Fenelon MA.

J Dairy Sci. 2018 Dec;101(12):10819-10830. doi: 10.3168/jds.2017-14177. Epub 2018 Sep 20.


Kinetic analysis of cellulose synthase of Gluconacetobacter hansenii in whole cells and in purified form.

McManus JB, Wilson L, Yang H, Kubicki JD, Tien M.

Enzyme Microb Technol. 2018 Dec;119:24-29. doi: 10.1016/j.enzmictec.2018.08.005. Epub 2018 Aug 23.


Carnivore conservation needs evidence-based livestock protection.

van Eeden LM, Eklund A, Miller JRB, López-Bao JV, Chapron G, Cejtin MR, Crowther MS, Dickman CR, Frank J, Krofel M, Macdonald DW, McManus J, Meyer TK, Middleton AD, Newsome TM, Ripple WJ, Ritchie EG, Schmitz OJ, Stoner KJ, Tourani M, Treves A.

PLoS Biol. 2018 Sep 18;16(9):e2005577. doi: 10.1371/journal.pbio.2005577. eCollection 2018 Sep.


Grazing of dairy cows on pasture versus indoor feeding on total mixed ration: Effects on low-moisture part-skim Mozzarella cheese yield and quality characteristics in mid and late lactation.

Gulati A, Galvin N, Hennessy D, McAuliffe S, O'Donovan M, McManus JJ, Fenelon MA, Guinee TP.

J Dairy Sci. 2018 Oct;101(10):8737-8756. doi: 10.3168/jds.2018-14566. Epub 2018 Aug 16.


Coherent deglacial changes in western Atlantic Ocean circulation.

Ng HC, Robinson LF, McManus JF, Mohamed KJ, Jacobel AW, Ivanovic RF, Gregoire LJ, Chen T.

Nat Commun. 2018 Jul 27;9(1):2947. doi: 10.1038/s41467-018-05312-3.


Burnout in the Emergency Department hospital staff at Cork University Hospital.

Chernoff P, Adedokun C, O'Sullivan I, McManus J, Payne A.

Ir J Med Sci. 2019 May;188(2):667-674. doi: 10.1007/s11845-018-1871-5. Epub 2018 Jul 26.


Initiation, Elongation, and Termination of Bacterial Cellulose Synthesis.

McManus JB, Yang H, Wilson L, Kubicki JD, Tien M.

ACS Omega. 2018 Mar 31;3(3):2690-2698. doi: 10.1021/acsomega.7b01808. Epub 2018 Mar 6.


Enhancing acute stroke services: a quality improvement project.

McGrath K, Cunningham N, Moloney E, O'Connor M, McManus J, Peters C, Lyons D.

BMJ Open Qual. 2018 Jul 7;7(3):e000258. doi: 10.1136/bmjoq-2017-000258. eCollection 2018.


Generation and Alkylation of α-Carbamyl Radicals via Organic Photoredox Catalysis.

McManus JB, Onuska NPR, Nicewicz DA.

J Am Chem Soc. 2018 Jul 25;140(29):9056-9060. doi: 10.1021/jacs.8b04890. Epub 2018 Jul 10.


Sediment Microbial Communities Influenced by Cool Hydrothermal Fluid Migration.

Zinke LA, Reese BK, McManus J, Wheat CG, Orcutt BN, Amend JP.

Front Microbiol. 2018 Jun 13;9:1249. doi: 10.3389/fmicb.2018.01249. eCollection 2018.


The impact of an Emergency Medical Technician basic course prior to medical school on medical students.

Wyatt TR, Wood EA, McManus J, Ma K, Wallach PM.

Med Educ Online. 2018 Dec;23(1):1474699. doi: 10.1080/10872981.2018.1474699.


Peptide Self-Assembly Measured Using Fluorescence Correlation Spectroscopy.

Mittag JJ, Rädler JO, McManus JJ.

Methods Mol Biol. 2018;1777:159-171. doi: 10.1007/978-1-4939-7811-3_8.


100- kyr cyclicity in volcanic ash emplacement: evidence from a 1.1 Myr tephra record from the NW Pacific.

Schindlbeck JC, Jegen M, Freundt A, Kutterolf S, Straub SM, Mleneck-Vautravers MJ, McManus JF.

Sci Rep. 2018 Mar 13;8(1):4440. doi: 10.1038/s41598-018-22595-0.


Biological rejuvenation of iron oxides in bioturbated marine sediments.

Beam JP, Scott JJ, McAllister SM, Chan CS, McManus J, Meysman FJR, Emerson D.

ISME J. 2018 May;12(5):1389-1394. doi: 10.1038/s41396-017-0032-6. Epub 2018 Jan 17.


A Robust Multiplex Mass Spectrometric Assay for Screening Small-Molecule Inhibitors of CD73 with Diverse Inhibition Modalities.

McManus J, He T, Gavigan JA, Marchand G, Vougier S, Bedel O, Ferrari P, Arrebola R, Gillespy T, Gregory RC, Licht S, Cheng H, Zhang B, Deng G.

SLAS Discov. 2018 Mar;23(3):264-273. doi: 10.1177/2472555217750386. Epub 2018 Jan 16.


Conserved non-AUG uORFs revealed by a novel regression analysis of ribosome profiling data.

Spealman P, Naik AW, May GE, Kuersten S, Freeberg L, Murphy RF, McManus J.

Genome Res. 2018 Feb;28(2):214-222. doi: 10.1101/gr.221507.117. Epub 2017 Dec 18.


Repeated storage of respired carbon in the equatorial Pacific Ocean over the last three glacial cycles.

Jacobel AW, McManus JF, Anderson RF, Winckler G.

Nat Commun. 2017 Nov 23;8(1):1727. doi: 10.1038/s41467-017-01938-x.


Outdoor grazing of dairy cows on pasture versus indoor feeding on total mixed ration: Effects on gross composition and mineral content of milk during lactation.

Gulati A, Galvin N, Lewis E, Hennessy D, O'Donovan M, McManus JJ, Fenelon MA, Guinee TP.

J Dairy Sci. 2018 Mar;101(3):2710-2723. doi: 10.3168/jds.2017-13338. Epub 2017 Sep 28.


High-Precision Simultaneous 18O/16O, 13C/12C, and 17O/16O Analyses for Microgram Quantities of CaCO3 by Tunable Infrared Laser Absorption Spectroscopy.

Sakai S, Matsuda S, Hikida T, Shimono A, McManus JB, Zahniser M, Nelson D, Dettman DL, Yang D, Ohkouchi N.

Anal Chem. 2017 Nov 7;89(21):11846-11852. doi: 10.1021/acs.analchem.7b03582. Epub 2017 Oct 18.


The path to longer and healthier lives for all Africans by 2030: the Lancet Commission on the future of health in sub-Saharan Africa.

Agyepong IA, Sewankambo N, Binagwaho A, Coll-Seck AM, Corrah T, Ezeh A, Fekadu A, Kilonzo N, Lamptey P, Masiye F, Mayosi B, Mboup S, Muyembe JJ, Pate M, Sidibe M, Simons B, Tlou S, Gheorghe A, Legido-Quigley H, McManus J, Ng E, O'Leary M, Enoch J, Kassebaum N, Piot P.

Lancet. 2018 Dec 23;390(10114):2803-2859. doi: 10.1016/S0140-6736(17)31509-X. Epub 2017 Sep 13. Review. No abstract available.


The mTOR inhibitor everolimus in combination with azacitidine in patients with relapsed/refractory acute myeloid leukemia: a phase Ib/II study.

Tan P, Tiong IS, Fleming S, Pomilio G, Cummings N, Droogleever M, McManus J, Schwarer A, Catalano J, Patil S, Avery S, Spencer A, Wei A.

Oncotarget. 2016 Nov 29;8(32):52269-52280. doi: 10.18632/oncotarget.13699. eCollection 2017 Aug 8.


Outcomes of endovascular treatment for acute large-vessel ischaemic stroke more than 6 h after symptom onset.

Motyer R, Kok HK, Asadi H, O'Hare A, Brennan P, Power S, Looby S, Nicholson P, Williams D, Murphy S, Hill MD, Goyal M, McManus J, O'Brien P, Thornton J.

J Intern Med. 2017 Dec;282(6):537-545. doi: 10.1111/joim.12680. Epub 2017 Sep 25.


The mechanical properties of individual cell spheroids.

Blumlein A, Williams N, McManus JJ.

Sci Rep. 2017 Aug 4;7(1):7346. doi: 10.1038/s41598-017-07813-5.


Predictive Model for Site-Selective Aryl and Heteroaryl C-H Functionalization via Organic Photoredox Catalysis.

Margrey KA, McManus JB, Bonazzi S, Zecri F, Nicewicz DA.

J Am Chem Soc. 2017 Aug 16;139(32):11288-11299. doi: 10.1021/jacs.7b06715. Epub 2017 Aug 7.


Phase Ib study of the mTOR inhibitor everolimus with low dose cytarabine in elderly acute myeloid leukemia.

Tiong IS, Tan P, McManus J, Cummings N, Sadawarte S, Catalano J, Hills R, Wei A.

Leuk Lymphoma. 2018 Feb;59(2):493-496. doi: 10.1080/10428194.2017.1334122. Epub 2017 Jun 8. No abstract available.


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