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Items: 1 to 50 of 345

1.

Rapid Detection of p53 Acetylation Status in Response to Cellular Stress Signaling.

Farkas M, McMahon SB.

Methods Mol Biol. 2019;1983:255-262. doi: 10.1007/978-1-4939-9434-2_15.

PMID:
31087303
2.

The lung-enriched p53 mutants V157F and R158L/P regulate a gain of function transcriptome in lung cancer.

Barta JA, Pauley K, Kossenkov AV, McMahon SB.

Carcinogenesis. 2019 May 8. pii: bgz087. doi: 10.1093/carcin/bgz087. [Epub ahead of print]

PMID:
31067569
3.

An ATF3-CreERT2 Knock-In Mouse for Axotomy-Induced Genetic Editing: Proof of Principle.

Holland SD, Ramer LM, McMahon SB, Denk F, Ramer MS.

eNeuro. 2019 Apr 9;6(2). pii: ENEURO.0025-19.2019. doi: 10.1523/ENEURO.0025-19.2019. eCollection 2019 Mar-Apr.

4.

Disruption of the Sensory System Affects Sterile Cutaneous Inflammation In Vivo.

La Russa F, Lopes DM, Hobbs C, Argunhan F, Brain S, Bevan S, Bennett DLH, McMahon SB.

J Invest Dermatol. 2019 Apr 8. pii: S0022-202X(19)31455-1. doi: 10.1016/j.jid.2019.01.037. [Epub ahead of print]

PMID:
30974165
5.
6.

Prospective comparative study of the effects of lidocaine on urodynamic and sensory parameters in bladder pain syndrome.

Offiah I, Dilloughery E, McMahon SB, O'Reilly BA.

Int Urogynecol J. 2019 Aug;30(8):1293-1301. doi: 10.1007/s00192-019-03892-2. Epub 2019 Mar 14.

7.

On-target and off-target effects of novel orthosteric and allosteric activators of GPR84.

Mancini SJ, Mahmud ZA, Jenkins L, Bolognini D, Newman R, Barnes M, Edye ME, McMahon SB, Tobin AB, Milligan G.

Sci Rep. 2019 Feb 12;9(1):1861. doi: 10.1038/s41598-019-38539-1.

8.

Characterisation of peripheral and central components of the rat monoiodoacetate model of Osteoarthritis.

Lockwood SM, Lopes DM, McMahon SB, Dickenson AH.

Osteoarthritis Cartilage. 2019 Apr;27(4):712-722. doi: 10.1016/j.joca.2018.12.017. Epub 2019 Jan 3.

9.

Stroke Recovery in Rats after 24-Hour-Delayed Intramuscular Neurotrophin-3 Infusion.

Duricki DA, Drndarski S, Bernanos M, Wood T, Bosch K, Chen Q, Shine HD, Simmons C, Williams SCR, McMahon SB, Begley DJ, Cash D, Moon LDF.

Ann Neurol. 2019 Jan;85(1):32-46. doi: 10.1002/ana.25386. Epub 2018 Dec 28.

10.

Comprehensive analysis of long noncoding RNA expression in dorsal root ganglion reveals cell-type specificity and dysregulation after nerve injury.

Baskozos G, Dawes JM, Austin JS, Antunes-Martins A, McDermott L, Clark AJ, Trendafilova T, Lees JG, McMahon SB, Mogil JS, Orengo C, Bennett DL.

Pain. 2019 Feb;160(2):463-485. doi: 10.1097/j.pain.0000000000001416.

11.

Neuromodulation in the restoration of function after spinal cord injury.

James ND, McMahon SB, Field-Fote EC, Bradbury EJ.

Lancet Neurol. 2018 Oct;17(10):905-917. doi: 10.1016/S1474-4422(18)30287-4. Epub 2018 Sep 18. Review.

PMID:
30264729
12.

Lung-Enriched Mutations in the p53 Tumor Suppressor: A Paradigm for Tissue-Specific Gain of Oncogenic Function.

Barta JA, McMahon SB.

Mol Cancer Res. 2019 Jan;17(1):3-9. doi: 10.1158/1541-7786.MCR-18-0357. Epub 2018 Sep 17.

PMID:
30224539
13.

Control of CCND1 ubiquitylation by the catalytic SAGA subunit USP22 is essential for cell cycle progression through G1 in cancer cells.

Gennaro VJ, Stanek TJ, Peck AR, Sun Y, Wang F, Qie S, Knudsen KE, Rui H, Butt T, Diehl JA, McMahon SB.

Proc Natl Acad Sci U S A. 2018 Oct 2;115(40):E9298-E9307. doi: 10.1073/pnas.1807704115. Epub 2018 Sep 17.

14.

Mice lacking Kcns1 in peripheral neurons show increased basal and neuropathic pain sensitivity.

Tsantoulas C, Denk F, Signore M, Nassar MA, Futai K, McMahon SB.

Pain. 2018 Aug;159(8):1641-1651. doi: 10.1097/j.pain.0000000000001255.

15.

Large Scale In Vivo Recording of Sensory Neuron Activity with GCaMP6.

Chisholm KI, Khovanov N, Lopes DM, La Russa F, McMahon SB.

eNeuro. 2018 Apr 6;5(1). pii: ENEURO.0417-17.2018. doi: 10.1523/ENEURO.0417-17.2018. eCollection 2018 Jan-Feb.

16.

Immune or Genetic-Mediated Disruption of CASPR2 Causes Pain Hypersensitivity Due to Enhanced Primary Afferent Excitability.

Dawes JM, Weir GA, Middleton SJ, Patel R, Chisholm KI, Pettingill P, Peck LJ, Sheridan J, Shakir A, Jacobson L, Gutierrez-Mecinas M, Galino J, Walcher J, Kühnemund J, Kuehn H, Sanna MD, Lang B, Clark AJ, Themistocleous AC, Iwagaki N, West SJ, Werynska K, Carroll L, Trendafilova T, Menassa DA, Giannoccaro MP, Coutinho E, Cervellini I, Tewari D, Buckley C, Leite MI, Wildner H, Zeilhofer HU, Peles E, Todd AJ, McMahon SB, Dickenson AH, Lewin GR, Vincent A, Bennett DL.

Neuron. 2018 Feb 21;97(4):806-822.e10. doi: 10.1016/j.neuron.2018.01.033. Epub 2018 Feb 8.

17.

Immune Cytokines and Their Receptors in Inflammatory Pain.

Cook AD, Christensen AD, Tewari D, McMahon SB, Hamilton JA.

Trends Immunol. 2018 Mar;39(3):240-255. doi: 10.1016/j.it.2017.12.003. Epub 2018 Jan 12. Review.

PMID:
29338939
18.

A PERK-miR-211 axis suppresses circadian regulators and protein synthesis to promote cancer cell survival.

Bu Y, Yoshida A, Chitnis N, Altman BJ, Tameire F, Oran A, Gennaro V, Armeson KE, McMahon SB, Wertheim GB, Dang CV, Ruggero D, Koumenis C, Fuchs SY, Diehl JA.

Nat Cell Biol. 2018 Jan;20(1):104-115. doi: 10.1038/s41556-017-0006-y. Epub 2017 Dec 11.

19.

Sex differences in peripheral not central immune responses to pain-inducing injury.

Lopes DM, Malek N, Edye M, Jager SB, McMurray S, McMahon SB, Denk F.

Sci Rep. 2017 Nov 28;7(1):16460. doi: 10.1038/s41598-017-16664-z.

20.

The Molecular Fingerprint of Dorsal Root and Trigeminal Ganglion Neurons.

Lopes DM, Denk F, McMahon SB.

Front Mol Neurosci. 2017 Sep 26;10:304. doi: 10.3389/fnmol.2017.00304. eCollection 2017.

21.

Using an engineered glutamate-gated chloride channel to silence sensory neurons and treat neuropathic pain at the source.

Weir GA, Middleton SJ, Clark AJ, Daniel T, Khovanov N, McMahon SB, Bennett DL.

Brain. 2017 Oct 1;140(10):2570-2585. doi: 10.1093/brain/awx201.

22.

Preoperative ultraviolet B inflammation in skin: Modelling individual differences in acute postoperative pain and neuro-immune interactions.

Lunn TH, Dawes JM, Denk F, Bennett DL, Husted H, Kehlet H, McMahon SB.

Eur J Pain. 2018 Jan;22(1):170-180. doi: 10.1002/ejp.1113. Epub 2017 Sep 14.

PMID:
28913854
23.

Structural and Functional Substitution of Deleted Primary Sensory Neurons by New Growth from Intrinsic Spinal Cord Nerve Cells: An Alternative Concept in Reconstruction of Spinal Cord Circuits.

James ND, Angéria M, Bradbury EJ, Damberg P, McMahon SB, Risling M, Carlstedt T.

Front Neurol. 2017 Jul 24;8:358. doi: 10.3389/fneur.2017.00358. eCollection 2017.

24.

Sensory processing of deep tissue nociception in the rat spinal cord and thalamic ventrobasal complex.

Sikandar S, West SJ, McMahon SB, Bennett DL, Dickenson AH.

Physiol Rep. 2017 Jul;5(14). pii: e13323. doi: 10.14814/phy2.13323.

25.

Nerve Growth Factor and Pain Mechanisms.

Denk F, Bennett DL, McMahon SB.

Annu Rev Neurosci. 2017 Jul 25;40:307-325. doi: 10.1146/annurev-neuro-072116-031121. Epub 2017 Apr 24. Review.

PMID:
28441116
26.

Delayed Accumulation of H3K27me3 on Nascent DNA Is Essential for Recruitment of Transcription Factors at Early Stages of Stem Cell Differentiation.

Petruk S, Cai J, Sussman R, Sun G, Kovermann SK, Mariani SA, Calabretta B, McMahon SB, Brock HW, Iacovitti L, Mazo A.

Mol Cell. 2017 Apr 20;66(2):247-257.e5. doi: 10.1016/j.molcel.2017.03.006. Epub 2017 Apr 11.

27.

Peripheral inflammatory pain sensitisation is independent of mast cell activation in male mice.

Lopes DM, Denk F, Chisholm KI, Suddason T, Durrieux C, Thakur M, Gentry C, McMahon SB.

Pain. 2017 Jul;158(7):1314-1322. doi: 10.1097/j.pain.0000000000000917.

28.

Transplantation of Cultured Olfactory Bulb Cells Prevents Abnormal Sensory Responses During Recovery From Dorsal Root Avulsion in the Rat.

Collins A, Li D, McMahon SB, Raisman G, Li Y.

Cell Transplant. 2017 May 9;26(5):913-924. doi: 10.3727/096368917X695353. Epub 2017 Mar 23.

29.

Neurobiological basis for pain vulnerability: why me?

Denk F, McMahon SB.

Pain. 2017 Apr;158 Suppl 1:S108-S114. doi: 10.1097/j.pain.0000000000000858. Review. No abstract available.

PMID:
28129218
30.

Manipulating the extracellular matrix: an animal model of the bladder pain syndrome.

Offiah I, Didangelos A, OʼReilly BA, McMahon SB.

Pain. 2017 Jan;158(1):161-170.

PMID:
27992393
31.

Repression of telomerase gene promoter requires human-specific genomic context and is mediated by multiple HDAC1-containing corepressor complexes.

Cheng, Zhao Y, Wang S, Zhang F, Russo M, McMahon SB, Zhu J.

FASEB J. 2017 Mar;31(3):1165-1178. doi: 10.1096/fj.201601111R. Epub 2016 Dec 9.

32.

Pharmacology of reflex blinks in the rat: a novel model for headache research.

Jones MG, Andreou AP, McMahon SB, Spanswick D.

J Headache Pain. 2016 Dec;17(1):96. Epub 2016 Oct 21.

33.
34.

Multi-focal control of mitochondrial gene expression by oncogenic MYC provides potential therapeutic targets in cancer.

Oran AR, Adams CM, Zhang XY, Gennaro VJ, Pfeiffer HK, Mellert HS, Seidel HE, Mascioli K, Kaplan J, Gaballa MR, Shen C, Rigoutsos I, King MP, Cotney JL, Arnold JJ, Sharma SD, Martinez-Outschoorn UE, Vakoc CR, Chodosh LA, Thompson JE, Bradner JE, Cameron CE, Shadel GS, Eischen CM, McMahon SB.

Oncotarget. 2016 Nov 8;7(45):72395-72414. doi: 10.18632/oncotarget.11718.

35.

A rare DNA contact mutation in cancer confers p53 gain-of-function and tumor cell survival via TNFAIP8 induction.

Monteith JA, Mellert H, Sammons MA, Kuswanto LA, Sykes SM, Resnick-Silverman L, Manfredi JJ, Berger SL, McMahon SB.

Mol Oncol. 2016 Oct;10(8):1207-20. doi: 10.1016/j.molonc.2016.05.007. Epub 2016 Jun 7.

36.

Persistent Alterations in Microglial Enhancers in a Model of Chronic Pain.

Denk F, Crow M, Didangelos A, Lopes DM, McMahon SB.

Cell Rep. 2016 May 24;15(8):1771-81. doi: 10.1016/j.celrep.2016.04.063. Epub 2016 May 12.

37.

Neurotrophic factors and their inhibitors in chronic pain treatment.

Kelleher JH, Tewari D, McMahon SB.

Neurobiol Dis. 2017 Jan;97(Pt B):127-138. doi: 10.1016/j.nbd.2016.03.025. Epub 2016 Apr 7. Review.

PMID:
27063668
38.

Altered potassium channel distribution and composition in myelinated axons suppresses hyperexcitability following injury.

Calvo M, Richards N, Schmid AB, Barroso A, Zhu L, Ivulic D, Zhu N, Anwandter P, Bhat MA, Court FA, McMahon SB, Bennett DL.

Elife. 2016 Apr 19;5:e12661. doi: 10.7554/eLife.12661.

39.

Neuregulin-1 controls an endogenous repair mechanism after spinal cord injury.

Bartus K, Galino J, James ND, Hernandez-Miranda LR, Dawes JM, Fricker FR, Garratt AN, McMahon SB, Ramer MS, Birchmeier C, Bennett DL, Bradbury EJ.

Brain. 2016 May;139(Pt 5):1394-416. doi: 10.1093/brain/aww039. Epub 2016 Mar 17.

40.

The Expression of Inflammatory Mediators in Bladder Pain Syndrome.

Offiah I, Didangelos A, Dawes J, Cartwright R, Khullar V, Bradbury EJ, O'Sullivan S, Williams D, Chessell IP, Pallas K, Graham G, O'Reilly BA, McMahon SB.

Eur Urol. 2016 Aug;70(2):283-90. doi: 10.1016/j.eururo.2016.02.058. Epub 2016 Mar 7.

41.

Ensuring transparency and minimization of methodologic bias in preclinical pain research: PPRECISE considerations.

Andrews NA, Latrémolière A, Basbaum AI, Mogil JS, Porreca F, Rice AS, Woolf CJ, Currie GL, Dworkin RH, Eisenach JC, Evans S, Gewandter JS, Gover TD, Handwerker H, Huang W, Iyengar S, Jensen MP, Kennedy JD, Lee N, Levine J, Lidster K, Machin I, McDermott MP, McMahon SB, Price TJ, Ross SE, Scherrer G, Seal RP, Sena ES, Silva E, Stone L, Svensson CI, Turk DC, Whiteside G.

Pain. 2016 Apr;157(4):901-9. doi: 10.1097/j.pain.0000000000000458. Review.

42.

Subtelomeric p53 binding prevents accumulation of DNA damage at human telomeres.

Tutton S, Azzam GA, Stong N, Vladimirova O, Wiedmer A, Monteith JA, Beishline K, Wang Z, Deng Z, Riethman H, McMahon SB, Murphy M, Lieberman PM.

EMBO J. 2016 Jan 18;35(2):193-207. doi: 10.15252/embj.201490880. Epub 2015 Dec 12.

43.

Tamoxifen induces cellular stress in the nervous system by inhibiting cholesterol synthesis.

Denk F, Ramer LM, Erskine EL, Nassar MA, Bogdanov Y, Signore M, Wood JN, McMahon SB, Ramer MS.

Acta Neuropathol Commun. 2015 Nov 26;3:74. doi: 10.1186/s40478-015-0255-6.

44.

Ultraviolet Radiation on the Skin: A Painful Experience?

Lopes DM, McMahon SB.

CNS Neurosci Ther. 2016 Feb;22(2):118-26. doi: 10.1111/cns.12444. Epub 2015 Aug 30. Review.

45.

Dimethylarginine dimethylaminohydrolase 1 is involved in spinal nociceptive plasticity.

DʼMello R, Sand CA, Pezet S, Leiper JM, Gaurilcikaite E, McMahon SB, Dickenson AH, Nandi M.

Pain. 2015 Oct;156(10):2052-60. doi: 10.1097/j.pain.0000000000000269.

46.

Crosstalk between the nociceptive and immune systems in host defence and disease.

McMahon SB, La Russa F, Bennett DL.

Nat Rev Neurosci. 2015 Jul;16(7):389-402. doi: 10.1038/nrn3946. Review.

PMID:
26087680
47.

The role of G-protein receptor 84 in experimental neuropathic pain.

Nicol LS, Dawes JM, La Russa F, Didangelos A, Clark AK, Gentry C, Grist J, Davies JB, Malcangio M, McMahon SB.

J Neurosci. 2015 Jun 10;35(23):8959-69. doi: 10.1523/JNEUROSCI.3558-14.2015.

48.

Human psychophysics and rodent spinal neurones exhibit peripheral and central mechanisms of inflammatory pain in the UVB and UVB heat rekindling models.

O'Neill J, Sikandar S, McMahon SB, Dickenson AH.

J Physiol. 2015 Sep 1;593(17):4029-42. doi: 10.1113/JP270294. Epub 2015 Aug 12.

49.

HDAC4 is required for inflammation-associated thermal hypersensitivity.

Crow M, Khovanov N, Kelleher JH, Sharma S, Grant AD, Bogdanov Y, Wood JN, McMahon SB, Denk F.

FASEB J. 2015 Aug;29(8):3370-8. doi: 10.1096/fj.14-264440. Epub 2015 Apr 22.

50.

Short-term effect of acute and repeated urinary bladder inflammation on thigmotactic behaviour in the laboratory rat.

Morland RH, Novejarque A, Huang W, Wodarski R, Denk F, Dawes JD, Pheby T, McMahon SB, Rice AS.

F1000Res. 2015 May 8;4:109. doi: 10.12688/f1000research.6255.1. eCollection 2015.

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