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Items: 1 to 50 of 88

1.

The Effects of Morphine, Baclofen, and Buspirone Alone and in Combination on Schedule-Controlled Responding and Hot Plate Antinociception in Rats.

Wilkerson JL, Felix JS, Restrepo LF, Ansari MI, Coop A, McMahon LR.

J Pharmacol Exp Ther. 2019 Sep;370(3):380-389. doi: 10.1124/jpet.118.255844. Epub 2019 Jun 24.

PMID:
31235534
2.

Kratom policy: The challenge of balancing therapeutic potential with public safety.

Prozialeck WC, Avery BA, Boyer EW, Grundmann O, Henningfield JE, Kruegel AC, McMahon LR, McCurdy CR, Swogger MT, Veltri CA, Singh D.

Int J Drug Policy. 2019 Aug;70:70-77. doi: 10.1016/j.drugpo.2019.05.003. Epub 2019 May 16.

3.

The effects of mitragynine and morphine on schedule-controlled responding and antinociception in rats.

Hiranita T, Leon F, Felix JS, Restrepo LF, Reeves ME, Pennington AE, Obeng S, Avery BA, McCurdy CR, McMahon LR, Wilkerson JL.

Psychopharmacology (Berl). 2019 Sep;236(9):2725-2734. doi: 10.1007/s00213-019-05247-7. Epub 2019 May 17.

PMID:
31098655
4.

Tolerance and dependence to Δ9-tetrahydrocannabinol in rhesus monkeys: Activity assessments.

Wilkerson JL, Schulze DR, McMahon LR.

PLoS One. 2019 Mar 12;14(3):e0209947. doi: 10.1371/journal.pone.0209947. eCollection 2019.

5.

Discriminative stimulus effects of mecamylamine and nicotine in rhesus monkeys: Central and peripheral mechanisms.

Cunningham CS, Moerke MJ, McMahon LR.

Pharmacol Biochem Behav. 2019 Apr;179:27-33. doi: 10.1016/j.pbb.2019.02.002. Epub 2019 Feb 6.

PMID:
30738085
6.

Nicotine-like discriminative stimulus effects of acetylcholinesterase inhibitors and a muscarinic receptor agonist in Rhesus monkeys.

Moerke MJ, McMahon LR.

Drug Dev Ind Pharm. 2019 May;45(5):861-867. doi: 10.1080/03639045.2019.1578787. Epub 2019 Feb 22.

PMID:
30712397
7.

Green tobacco sickness: mecamylamine, varenicline, and nicotine vaccine as clinical research tools and potential therapeutics.

McMahon LR.

Expert Rev Clin Pharmacol. 2019 Mar;12(3):189-195. doi: 10.1080/17512433.2019.1570844. Epub 2019 Jan 24. Review.

PMID:
30650314
8.

Differential cross-tolerance to the effects of nicotinic acetylcholine receptor drugs in C57BL/6J mice following chronic varenicline.

de Moura FB, McMahon LR.

Behav Pharmacol. 2019 Aug;30(5):412-421. doi: 10.1097/FBP.0000000000000452.

PMID:
30398980
9.

Rapid nicotine tolerance and cross-tolerance to varenicline in rhesus monkeys: Drug discrimination.

Moerke MJ, McMahon LR.

Exp Clin Psychopharmacol. 2018 Dec;26(6):541-548. doi: 10.1037/pha0000226. Epub 2018 Aug 13.

PMID:
30102063
10.

An OPAA enzyme mutant with increased catalytic efficiency on the nerve agents sarin, soman, and GP.

Bae SY, Myslinski JM, McMahon LR, Height JJ, Bigley AN, Raushel FM, Harvey SP.

Enzyme Microb Technol. 2018 May;112:65-71. doi: 10.1016/j.enzmictec.2017.11.001. Epub 2017 Nov 21.

PMID:
29499783
11.

Apparent Affinity Estimates and Reversal of the Effects of Synthetic Cannabinoids AM-2201, CP-47,497, JWH-122, and JWH-250 by Rimonabant in Rhesus Monkeys.

Hruba L, McMahon LR.

J Pharmacol Exp Ther. 2017 Aug;362(2):278-286. doi: 10.1124/jpet.117.240572. Epub 2017 May 22.

12.

The contribution of α4β2 and non-α4β2 nicotinic acetylcholine receptors to the discriminative stimulus effects of nicotine and varenicline in mice.

de Moura FB, McMahon LR.

Psychopharmacology (Berl). 2017 Mar;234(5):781-792. doi: 10.1007/s00213-016-4514-4. Epub 2016 Dec 27.

13.

The discriminative stimulus effects of i.v. nicotine in rhesus monkeys: Pharmacokinetics and apparent pA2 analysis with dihydro-β-erythroidine.

Moerke MJ, Zhu AZ, Tyndale RF, Javors MA, McMahon LR.

Neuropharmacology. 2017 Apr;116:9-17. doi: 10.1016/j.neuropharm.2016.12.003. Epub 2016 Dec 8.

14.

Attenuated nicotine-like effects of varenicline but not other nicotinic ACh receptor agonists in monkeys receiving nicotine daily.

Cunningham CS, Moerke MJ, Javors MA, Carroll FI, McMahon LR.

Br J Pharmacol. 2016 Dec;173(24):3454-3466. doi: 10.1111/bph.13635. Epub 2016 Nov 6.

15.

Enhanced discriminative stimulus effects of Δ(9)-THC in the presence of cannabidiol and 8-OH-DPAT in rhesus monkeys.

McMahon LR.

Drug Alcohol Depend. 2016 Aug 1;165:87-93. doi: 10.1016/j.drugalcdep.2016.05.016. Epub 2016 Jun 3.

16.

Effects of nicotine in combination with drugs described as positive allosteric nicotinic acetylcholine receptor modulators in vitro: discriminative stimulus and hypothermic effects in mice.

Moerke MJ, de Moura FB, Koek W, McMahon LR.

Eur J Pharmacol. 2016 Sep 5;786:169-178. doi: 10.1016/j.ejphar.2016.05.032. Epub 2016 May 27.

17.
18.

The rise (and fall?) of drug discrimination research.

McMahon LR.

Drug Alcohol Depend. 2015 Jun 1;151:284-8. No abstract available.

19.

Full Fatty Acid Amide Hydrolase Inhibition Combined with Partial Monoacylglycerol Lipase Inhibition: Augmented and Sustained Antinociceptive Effects with Reduced Cannabimimetic Side Effects in Mice.

Ghosh S, Kinsey SG, Liu QS, Hruba L, McMahon LR, Grim TW, Merritt CR, Wise LE, Abdullah RA, Selley DE, Sim-Selley LJ, Cravatt BF, Lichtman AH.

J Pharmacol Exp Ther. 2015 Aug;354(2):111-20. doi: 10.1124/jpet.115.222851. Epub 2015 May 21.

20.

Simultaneous inhibition of fatty acid amide hydrolase and monoacylglycerol lipase shares discriminative stimulus effects with Δ9-tetrahydrocannabinol in mice.

Hruba L, Seillier A, Zaki A, Cravatt BF, Lichtman AH, Giuffrida A, McMahon LR.

J Pharmacol Exp Ther. 2015 May;353(2):261-8. doi: 10.1124/jpet.115.222836. Epub 2015 Feb 24.

21.

The discriminative stimulus effects of mecamylamine in nicotine-treated and untreated rhesus monkeys.

Cunningham CS, Moerke MJ, McMahon LR.

Behav Pharmacol. 2014 Aug;25(4):296-305. doi: 10.1097/FBP.0000000000000054.

22.

JWH-018 in rhesus monkeys: differential antagonism of discriminative stimulus, rate-decreasing, and hypothermic effects.

Rodriguez JS, McMahon LR.

Eur J Pharmacol. 2014 Oct 5;740:151-9. doi: 10.1016/j.ejphar.2014.06.023. Epub 2014 Jun 24.

23.

Discriminative stimulus and hypothermic effects of some derivatives of the nAChR agonist epibatidine in mice.

Rodriguez JS, Cunningham CS, Moura FB, Ondachi P, Carroll FI, McMahon LR.

Psychopharmacology (Berl). 2014 Dec;231(23):4455-66. doi: 10.1007/s00213-014-3589-z. Epub 2014 May 7.

24.

Blood levels do not predict behavioral or physiological effects of Δ⁹-tetrahydrocannabinol in rhesus monkeys with different patterns of exposure.

Ginsburg BC, Hruba L, Zaki A, Javors MA, McMahon LR.

Drug Alcohol Depend. 2014 Jun 1;139:1-8. doi: 10.1016/j.drugalcdep.2014.02.696. Epub 2014 Mar 19.

25.

The cannabinoid agonist HU-210: pseudo-irreversible discriminative stimulus effects in rhesus monkeys.

Hruba L, McMahon LR.

Eur J Pharmacol. 2014 Mar 15;727:35-42. doi: 10.1016/j.ejphar.2014.01.041. Epub 2014 Jan 30.

26.

Multiple nicotine training doses in mice as a basis for differentiating the effects of smoking cessation aids.

Cunningham CS, McMahon LR.

Psychopharmacology (Berl). 2013 Jul;228(2):321-33. doi: 10.1007/s00213-013-3037-5. Epub 2013 Mar 14.

27.

Apparent inverse relationship between cannabinoid agonist efficacy and tolerance/cross-tolerance produced by Δ⁹-tetrahydrocannabinol treatment in rhesus monkeys.

Hruba L, Ginsburg BC, McMahon LR.

J Pharmacol Exp Ther. 2012 Sep;342(3):843-9. doi: 10.1124/jpet.112.196444. Epub 2012 Jun 20.

28.

Acetaminophen differentially enhances social behavior and cortical cannabinoid levels in inbred mice.

Gould GG, Seillier A, Weiss G, Giuffrida A, Burke TF, Hensler JG, Rock C, Tristan A, McMahon LR, Salazar A, O'Connor JC, Satsangi N, Satsangi RK, Gu TT, Treat K, Smolik C, Schultz ST.

Prog Neuropsychopharmacol Biol Psychiatry. 2012 Aug 7;38(2):260-9. doi: 10.1016/j.pnpbp.2012.04.011. Epub 2012 Apr 21.

29.

Pharmacologic characterization of a nicotine-discriminative stimulus in rhesus monkeys.

Cunningham CS, Javors MA, McMahon LR.

J Pharmacol Exp Ther. 2012 Jun;341(3):840-9. doi: 10.1124/jpet.112.193078. Epub 2012 Mar 21.

30.

Interactions between dopamine transporter and cannabinoid receptor ligands in rhesus monkeys.

Schulze DR, Carroll FI, McMahon LR.

Psychopharmacology (Berl). 2012 Aug;222(3):425-38. doi: 10.1007/s00213-012-2661-9. Epub 2012 Feb 29.

31.

Purity of synthetic cannabinoids sold online for recreational use.

Ginsburg BC, McMahon LR, Sanchez JJ, Javors MA.

J Anal Toxicol. 2012 Jan-Feb;36(1):66-8. doi: 10.1093/jat/bkr018.

32.

JWH-018 and JWH-073: Δ⁹-tetrahydrocannabinol-like discriminative stimulus effects in monkeys.

Ginsburg BC, Schulze DR, Hruba L, McMahon LR.

J Pharmacol Exp Ther. 2012 Jan;340(1):37-45. doi: 10.1124/jpet.111.187757. Epub 2011 Sep 30.

33.

The fatty acid amide hydrolase inhibitor URB 597: interactions with anandamide in rhesus monkeys.

Stewart JL, McMahon LR.

Br J Pharmacol. 2011 Sep;164(2b):655-66. doi: 10.1111/j.1476-5381.2011.01388.x.

34.

Tolerance and cross-tolerance to cannabinoids in mice: schedule-controlled responding and hypothermia.

Singh H, Schulze DR, McMahon LR.

Psychopharmacology (Berl). 2011 Jun;215(4):665-75. doi: 10.1007/s00213-010-2162-7. Epub 2011 Jan 19.

35.

The effects of nicotine, varenicline, and cytisine on schedule-controlled responding in mice: differences in α4β2 nicotinic receptor activation.

Cunningham CS, McMahon LR.

Eur J Pharmacol. 2011 Mar 1;654(1):47-52. doi: 10.1016/j.ejphar.2010.12.003. Epub 2010 Dec 21.

36.

Chronic Δ⁹-tetrahydrocannabinol treatment in rhesus monkeys: differential tolerance and cross-tolerance among cannabinoids.

McMahon LR.

Br J Pharmacol. 2011 Mar;162(5):1060-73. doi: 10.1111/j.1476-5381.2010.01116.x.

37.

Quantification of rimonabant (SR 141716A) in monkey plasma using HPLC with UV detection.

Javors MA, Sanchez JJ, McMahon LR.

J Chromatogr Sci. 2010 Jul;48(6):491-5.

38.

Rimonabant-induced Delta9-tetrahydrocannabinol withdrawal in rhesus monkeys: discriminative stimulus effects and other withdrawal signs.

Stewart JL, McMahon LR.

J Pharmacol Exp Ther. 2010 Jul;334(1):347-56. doi: 10.1124/jpet.110.168435. Epub 2010 Apr 7.

39.

In vivo pharmacology of endocannabinoids and their metabolic inhibitors: therapeutic implications in Parkinson's disease and abuse liability.

Giuffrida A, McMahon LR.

Prostaglandins Other Lipid Mediat. 2010 Apr;91(3-4):90-103. doi: 10.1016/j.prostaglandins.2009.05.004. Epub 2009 Jun 10. Review.

40.

Cannabinoid CB1 receptor antagonists as potential pharmacotherapies for drug abuse disorders.

Beardsley PM, Thomas BF, McMahon LR.

Int Rev Psychiatry. 2009 Apr;21(2):134-42. doi: 10.1080/09540260902782786. Review.

PMID:
19367507
41.

Acute cross tolerance to midazolam, and not pentobarbital and pregnanolone, after a single dose of chlordiazepoxide in monkeys discriminating midazolam.

Gerak LR, McMahon LR, France CP.

Behav Pharmacol. 2008 Dec;19(8):796-804. doi: 10.1097/FBP.0b013e32831c3b40.

42.

Some effects of dopamine transporter and receptor ligands on discriminative stimulus, physiologic, and directly observable indices of opioid withdrawal in rhesus monkeys.

McMahon LR, Li JX, Carroll FI, France CP.

Psychopharmacology (Berl). 2009 Apr;203(2):411-20. doi: 10.1007/s00213-008-1242-4. Epub 2008 Jul 18. Erratum in: Psychopharmacology (Berl). 2008 Nov;200(4):611.

43.
44.

Interactions between Delta(9)-tetrahydrocannabinol and mu opioid receptor agonists in rhesus monkeys: discrimination and antinociception.

Li JX, McMahon LR, Gerak LR, Becker GL, France CP.

Psychopharmacology (Berl). 2008 Aug;199(2):199-208. doi: 10.1007/s00213-008-1157-0. Epub 2008 May 10.

45.

Basic measures of food intake.

Wellman PJ, McMahon LR.

Curr Protoc Neurosci. 2001 May;Chapter 8:Unit 8.6B. doi: 10.1002/0471142301.ns0806bs03.

PMID:
18428545
46.

Comparison of naltrexone, 6alpha-naltrexol, and 6beta-naltrexol in morphine-dependent and in nondependent rhesus monkeys.

Li JX, McMahon LR, France CP.

Psychopharmacology (Berl). 2008 Jan;195(4):479-86. Epub 2007 Sep 16.

PMID:
17874317
47.

Cannabinoid agonists differentially substitute for the discriminative stimulus effects of Delta(9)-tetrahydrocannabinol in C57BL/6J mice.

McMahon LR, Ginsburg BC, Lamb RJ.

Psychopharmacology (Berl). 2008 Jul;198(4):487-95. Epub 2007 Aug 3.

48.
49.

Changes in relative potency among positive GABA(A) receptor modulators upon discontinuation of chronic benzodiazepine treatment in rhesus monkeys.

McMahon LR, Javors MA, France CP.

Psychopharmacology (Berl). 2007 May;192(1):135-45. Epub 2007 Jan 24.

PMID:
17245585
50.

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