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Items: 1 to 50 of 84

1.

Age and pattern of the southern high-latitude continental end-Permian extinction constrained by multiproxy analysis.

Fielding CR, Frank TD, McLoughlin S, Vajda V, Mays C, Tevyaw AP, Winguth A, Winguth C, Nicoll RS, Bocking M, Crowley JL.

Nat Commun. 2019 Jan 23;10(1):385. doi: 10.1038/s41467-018-07934-z.

2.

Anticipatory versus reactive spatial attentional bias to threat.

Gladwin TE, Möbius M, McLoughlin S, Tyndall I.

Br J Psychol. 2019 Feb;110(1):3-14. doi: 10.1111/bjop.12309. Epub 2018 May 10.

PMID:
29745437
3.

Emerging Approaches for the Identification of Protein Targets of Small Molecules - A Practitioners' Perspective.

Comess KM, McLoughlin SM, Oyer JA, Richardson PL, Stöckmann H, Vasudevan A, Warder SE.

J Med Chem. 2018 Oct 11;61(19):8504-8535. doi: 10.1021/acs.jmedchem.7b01921. Epub 2018 Jun 6.

PMID:
29718665
4.

Housing for People with Substance Use Disorders: One Size Does Not Fit All Tenants-Assessment of 16 Housing Services and Suggestions for Improvement Based on Real World Experience.

Littlewood R, Gilman M, McLoughlin S.

Community Ment Health J. 2019 Feb;55(2):331-335. doi: 10.1007/s10597-018-0279-z. Epub 2018 Apr 27.

PMID:
29704088
5.

Molecular signatures of fossil leaves provide unexpected new evidence for extinct plant relationships.

Vajda V, Pucetaite M, McLoughlin S, Engdahl A, Heimdal J, Uvdal P.

Nat Ecol Evol. 2017 Aug;1(8):1093-1099. doi: 10.1038/s41559-017-0224-5. Epub 2017 Jul 3.

PMID:
29046567
6.

Molecular basis of USP7 inhibition by selective small-molecule inhibitors.

Turnbull AP, Ioannidis S, Krajewski WW, Pinto-Fernandez A, Heride C, Martin ACL, Tonkin LM, Townsend EC, Buker SM, Lancia DR, Caravella JA, Toms AV, Charlton TM, Lahdenranta J, Wilker E, Follows BC, Evans NJ, Stead L, Alli C, Zarayskiy VV, Talbot AC, Buckmelter AJ, Wang M, McKinnon CL, Saab F, McGouran JF, Century H, Gersch M, Pittman MS, Marshall CG, Raynham TM, Simcox M, Stewart LMD, McLoughlin SB, Escobedo JA, Bair KW, Dinsmore CJ, Hammonds TR, Kim S, Urbé S, Clague MJ, Kessler BM, Komander D.

Nature. 2017 Oct 26;550(7677):481-486. doi: 10.1038/nature24451. Epub 2017 Oct 18.

7.

A High-Throughput Screening Triage Workflow to Authenticate a Novel Series of PFKFB3 Inhibitors.

St-Gallay SA, Bennett N, Critchlow SE, Curtis N, Davies G, Debreczeni J, Evans N, Hardern I, Holdgate G, Jones NP, Leach L, Maman S, McLoughlin S, Preston M, Rigoreau L, Thomas A, Turnbull AP, Walker G, Walsh J, Ward RA, Wheatley E, Winter-Holt J.

SLAS Discov. 2018 Jan;23(1):11-22. doi: 10.1177/2472555217732289. Epub 2017 Sep 25.

PMID:
28945981
8.

Lived Experience, Stakeholder Evaluation and the Participatory Design of Assisted Living Technology.

Cahill J, McLoughlin S, Wetherall S.

Stud Health Technol Inform. 2017;242:64-71.

PMID:
28873778
9.
10.

Discovery and Characterization of Novel Nonsubstrate and Substrate NAMPT Inhibitors.

Wilsbacher JL, Cheng M, Cheng D, Trammell SAJ, Shi Y, Guo J, Koeniger SL, Kovar PJ, He Y, Selvaraju S, Heyman HR, Sorensen BK, Clark RF, Hansen TM, Longenecker KL, Raich D, Korepanova AV, Cepa S, Towne DL, Abraham VC, Tang H, Richardson PL, McLoughlin SM, Badagnani I, Curtin ML, Michaelides MR, Maag D, Buchanan FG, Chiang GG, Gao W, Rosenberg SH, Brenner C, Tse C.

Mol Cancer Ther. 2017 Jul;16(7):1236-1245. doi: 10.1158/1535-7163.MCT-16-0819. Epub 2017 May 3.

11.

Transmembrane TNF-dependent uptake of anti-TNF antibodies.

Deora A, Hegde S, Lee J, Choi CH, Chang Q, Lee C, Eaton L, Tang H, Wang D, Lee D, Michalak M, Tomlinson M, Tao Q, Gaur N, Harvey B, McLoughlin S, Labkovsky B, Ghayur T.

MAbs. 2017 May/Jun;9(4):680-695. doi: 10.1080/19420862.2017.1304869. Epub 2017 Mar 21.

12.

How does elevated ozone reduce methane emissions from peatlands?

Toet S, Oliver V, Ineson P, McLoughlin S, Helgason T, Peacock S, Stott AW, Barnes J, Ashmore M.

Sci Total Environ. 2017 Feb 1;579:60-71. doi: 10.1016/j.scitotenv.2016.10.188. Epub 2016 Nov 17.

PMID:
27866746
13.

A method for isolation of cone photoreceptors from adult zebrafish retinae.

Glaviano A, Smith AJ, Blanco A, McLoughlin S, Cederlund ML, Heffernan T, Sapetto-Rebow B, Alvarez Y, Yin J, Kennedy BN.

BMC Neurosci. 2016 Nov 7;17(1):71.

14.

Timing of expression of the core clock gene Bmal1 influences its effects on aging and survival.

Yang G, Chen L, Grant GR, Paschos G, Song WL, Musiek ES, Lee V, McLoughlin SC, Grosser T, Cotsarelis G, FitzGerald GA.

Sci Transl Med. 2016 Feb 3;8(324):324ra16. doi: 10.1126/scitranslmed.aad3305. Epub 2016 Feb 3.

15.

Safety and Efficacy Outcomes of Home and Hospital Warfarin Management Within a Pediatric Anticoagulation Clinic.

Jones S, McLoughlin S, Piovesan D, Savoia H, Monagle P, Newall F.

J Pediatr Hematol Oncol. 2016 Apr;38(3):216-20. doi: 10.1097/MPH.0000000000000502.

PMID:
26808370
16.

Target Identification of Compounds from a Cell Viability Phenotypic Screen Using a Bead/Lysate-Based Affinity Capture Platform.

Tang H, Duggan S, Richardson PL, Marin V, Warder SE, McLoughlin SM.

J Biomol Screen. 2016 Feb;21(2):201-11. doi: 10.1177/1087057115622431. Epub 2015 Dec 16.

PMID:
26676096
17.

Fossilized spermatozoa preserved in a 50-Myr-old annelid cocoon from Antarctica.

Bomfleur B, Mörs T, Ferraguti M, Reguero MA, McLoughlin S.

Biol Lett. 2015 Jul;11(7). pii: 20150431. doi: 10.1098/rsbl.2015.0431.

18.
19.

Structure-Based Design of Potent and Selective Inhibitors of the Metabolic Kinase PFKFB3.

Boyd S, Brookfield JL, Critchlow SE, Cumming IA, Curtis NJ, Debreczeni J, Degorce SL, Donald C, Evans NJ, Groombridge S, Hopcroft P, Jones NP, Kettle JG, Lamont S, Lewis HJ, MacFaull P, McLoughlin SB, Rigoreau LJ, Smith JM, St-Gallay S, Stock JK, Turnbull AP, Wheatley ER, Winter J, Wingfield J.

J Med Chem. 2015 Apr 23;58(8):3611-25. doi: 10.1021/acs.jmedchem.5b00352. Epub 2015 Apr 13.

PMID:
25849762
20.

Clocks and cardiovascular function.

McLoughlin SC, Haines P, FitzGerald GA.

Methods Enzymol. 2015;552:211-28. doi: 10.1016/bs.mie.2014.11.029. Epub 2014 Dec 26. Review.

21.

Using more than the oldest fossils: dating osmundaceae with three Bayesian clock approaches.

Grimm GW, Kapli P, Bomfleur B, McLoughlin S, Renner SS.

Syst Biol. 2015 May;64(3):396-405. doi: 10.1093/sysbio/syu108. Epub 2014 Dec 9.

PMID:
25503771
22.

Early evidence of xeromorphy in angiosperms: stomatal encryption in a new eocene species of Banksia (Proteaceae) from Western Australia.

Carpenter RJ, McLoughlin S, Hill RS, McNamara KJ, Jordan GJ.

Am J Bot. 2014 Sep;101(9):1486-97. doi: 10.3732/ajb.1400191.

23.

Fossilized nuclei and chromosomes reveal 180 million years of genomic stasis in royal ferns.

Bomfleur B, McLoughlin S, Vajda V.

Science. 2014 Mar 21;343(6177):1376-7. doi: 10.1126/science.1249884.

PMID:
24653037
24.

Knitting up the raveled sleave of care.

Yang G, Paschos G, Curtis AM, Musiek ES, McLoughlin SC, FitzGerald GA.

Sci Transl Med. 2013 Nov 20;5(212):212rv3. doi: 10.1126/scitranslmed.3007225. Review.

PMID:
24259052
25.

Single-molecule resolution of protein structure and interfacial dynamics on biomaterial surfaces.

McLoughlin SY, Kastantin M, Schwartz DK, Kaar JL.

Proc Natl Acad Sci U S A. 2013 Nov 26;110(48):19396-401. doi: 10.1073/pnas.1311761110. Epub 2013 Nov 14.

26.

Peronosporomycetes (Oomycota) from a Middle Permian permineralised peat within the Bainmedart Coal Measures, Prince Charles Mountains, Antarctica.

Slater BJ, McLoughlin S, Hilton J.

PLoS One. 2013 Aug 2;8(8):e70707. doi: 10.1371/journal.pone.0070707. Print 2013.

27.

Inhibition of the Pim1 oncogene results in diminished visual function.

Yin J, Shine L, Raycroft F, Deeti S, Reynolds A, Ackerman KM, Glaviano A, O'Farrell S, O'Leary O, Kilty C, Kennedy C, McLoughlin S, Rice M, Russell E, Higgins DG, Hyde DR, Kennedy BN.

PLoS One. 2012;7(12):e52177. doi: 10.1371/journal.pone.0052177. Epub 2012 Dec 26.

28.

Between a rock and a hard place: how to align our circadian rhythms?

McLoughlin SC, FitzGerald GA.

Circulation. 2013 Jan 1;127(1):19-20. doi: 10.1161/CIRCULATIONAHA.112.150417. Epub 2012 Nov 21. No abstract available.

PMID:
23172837
29.

Parallel evolution of angiosperm colour signals: common evolutionary pressures linked to hymenopteran vision.

Dyer AG, Boyd-Gerny S, McLoughlin S, Rosa MG, Simonov V, Wong BB.

Proc Biol Sci. 2012 Sep 7;279(1742):3606-15. doi: 10.1098/rspb.2012.0827. Epub 2012 Jun 6.

30.

Loose body following cross-pin fixation for anterior cruciate ligament reconstruction.

Boden RA, Razak A, Hussain SM, McLoughlin SJ.

J Orthop Traumatol. 2013 Jun;14(2):155-7. doi: 10.1007/s10195-012-0194-y. Epub 2012 Apr 17.

31.

Maternal topoisomerase II alpha, not topoisomerase II beta, enables embryonic development of zebrafish top2a-/- mutants.

Sapetto-Rebow B, McLoughlin SC, O'Shea LC, O'Leary O, Willer JR, Alvarez Y, Collery R, O'Sullivan J, Van Eeden F, Hensey C, Kennedy BN.

BMC Dev Biol. 2011 Nov 23;11:71. doi: 10.1186/1471-213X-11-71.

32.

Bcl-XL represents a druggable molecular vulnerability during aurora B inhibitor-mediated polyploidization.

Shah OJ, Lin X, Li L, Huang X, Li J, Anderson MG, Tang H, Rodriguez LE, Warder SE, McLoughlin S, Chen J, Palma J, Glaser KB, Donawho CK, Fesik SW, Shen Y.

Proc Natl Acad Sci U S A. 2010 Jul 13;107(28):12634-9. doi: 10.1073/pnas.0913615107. Epub 2010 Jun 28.

33.

Simultaneous reduction and digestion of proteins with disulfide bonds for hydrogen/deuterium exchange monitored by mass spectrometry.

Zhang HM, McLoughlin SM, Frausto SD, Tang H, Emmett MR, Marshall AG.

Anal Chem. 2010 Feb 15;82(4):1450-4. doi: 10.1021/ac902550n.

34.

Integrating multiple genome annotation databases improves the interpretation of microarray gene expression data.

Yin J, McLoughlin S, Jeffery IB, Glaviano A, Kennedy B, Higgins DG.

BMC Genomics. 2010 Jan 20;11:50. doi: 10.1186/1471-2164-11-50.

35.

Psychiatrists' use, knowledge and attitudes to first- and second-generation antipsychotic long-acting injections: comparisons over 5 years.

Patel MX, Haddad PM, Chaudhry IB, McLoughlin S, Husain N, David AS.

J Psychopharmacol. 2010 Oct;24(10):1473-82. doi: 10.1177/0269881109104882. Epub 2009 May 28.

PMID:
19477883
36.

Discovery, identification, and characterization of candidate pharmacodynamic markers of methionine aminopeptidase-2 inhibition.

Warder SE, Tucker LA, McLoughlin SM, Strelitzer TJ, Meuth JL, Zhang Q, Sheppard GS, Richardson PL, Lesniewski R, Davidsen SK, Bell RL, Rogers JC, Wang J.

J Proteome Res. 2008 Nov;7(11):4807-20. doi: 10.1021/pr800388p. Epub 2008 Oct 2.

PMID:
18828628
37.

A compromise required by gene sharing enables survival: Implications for evolution of new enzyme activities.

McLoughlin SY, Copley SD.

Proc Natl Acad Sci U S A. 2008 Sep 9;105(36):13497-502. doi: 10.1073/pnas.0804804105. Epub 2008 Aug 29.

38.

Duplication and divergence of zebrafish CRALBP genes uncovers novel role for RPE- and Muller-CRALBP in cone vision.

Collery R, McLoughlin S, Vendrell V, Finnegan J, Crabb JW, Saari JC, Kennedy BN.

Invest Ophthalmol Vis Sci. 2008 Sep;49(9):3812-20. doi: 10.1167/iovs.08-1957. Epub 2008 May 23.

PMID:
18502992
39.

Seed ferns survived the end-Cretaceous mass extinction in Tasmania.

McLoughlin S, Carpenter RJ, Jordan GJ, Hill RS.

Am J Bot. 2008 Apr;95(4):465-71. doi: 10.3732/ajb.95.4.465.

40.

Should patients with symptomatic BPH have a trial of medical therapy by their general practitioner prior to referral for urological assessment?

McGuire BB, O'Brien MF, McLoughlin S, O'Malley KJ, Fitzpatrick JM.

Ir Med J. 2007 Apr;100(4):428-9.

PMID:
17566476
41.

Identification of zygotic genes expressed at the midblastula transition in zebrafish.

O'Boyle S, Bree RT, McLoughlin S, Grealy M, Byrnes L.

Biochem Biophys Res Commun. 2007 Jun 29;358(2):462-8. Epub 2007 Apr 26.

PMID:
17490614
42.

Socioeconomic provisions for specialist training in Italy and the UK: integrating the differences.

Fusar-Poli P, McLoughlin S, Mongelli A, Cortesi M, Politi P.

Postgrad Med J. 2006 Dec;82(974):810-2.

43.
44.

Chemoenzymatic approaches for streamlined detection of active site modifications on thiotemplate assembly lines using mass spectrometry.

McLoughlin SM, Mazur MT, Miller LM, Yin J, Liu F, Walsh CT, Kelleher NL.

Biochemistry. 2005 Nov 1;44(43):14159-69.

PMID:
16245932
45.

Genetically encoded short peptide tag for versatile protein labeling by Sfp phosphopantetheinyl transferase.

Yin J, Straight PD, McLoughlin SM, Zhou Z, Lin AJ, Golan DE, Kelleher NL, Kolter R, Walsh CT.

Proc Natl Acad Sci U S A. 2005 Nov 1;102(44):15815-20. Epub 2005 Oct 19.

46.
47.

nanor, a novel zygotic gene, is expressed initially at the midblastula transition in zebrafish.

Bree RT, McLoughlin S, Jin SW, McMeel OM, Stainier DY, Grealy M, Byrnes L.

Biochem Biophys Res Commun. 2005 Aug 5;333(3):722-8.

PMID:
15961062
48.

Increased expression of a bacterial phosphotriesterase in Escherichia coli through directed evolution.

McLoughlin SY, Jackson C, Liu JW, Ollis D.

Protein Expr Purif. 2005 Jun;41(2):433-40.

PMID:
15866732
49.

Elucidating the substrate specificity and condensation domain activity of FkbP, the FK520 pipecolate-incorporating enzyme.

Gatto GJ Jr, McLoughlin SM, Kelleher NL, Walsh CT.

Biochemistry. 2005 Apr 26;44(16):5993-6002.

PMID:
15835888
50.

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