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Items: 1 to 50 of 130

1.

Mature neutrophils suppress T cell immunity in ovarian cancer microenvironment.

Singel KL, Emmons TR, Khan ANH, Mayor PC, Shen S, Wong JT, Morrell K, Eng KH, Mark J, Bankert RB, Matsuzaki J, Koya RC, Blom AM, McLeish KR, Qu J, Ram S, Moysich KB, Abrams SI, Odunsi K, Zsiros E, Segal BH.

JCI Insight. 2019 Mar 7;4(5). pii: 122311. doi: 10.1172/jci.insight.122311. eCollection 2019 Mar 7.

2.

Neutrophil exocytosis induces podocyte cytoskeletal reorganization and proteinuria in experimental glomerulonephritis.

Caster DJ, Korte EA, Tan M, Barati MT, Tandon S, Creed TM, Salant DJ, Hata JL, Epstein PN, Huang H, Powell DW, McLeish KR.

Am J Physiol Renal Physiol. 2018 Sep 1;315(3):F595-F606. doi: 10.1152/ajprenal.00039.2018. Epub 2018 May 23.

3.

Biomarker enhanced risk prediction for development of AKI after cardiac surgery.

Merchant ML, Brier ME, Slaughter MS, Klein JB, McLeish KR.

BMC Nephrol. 2018 May 2;19(1):102. doi: 10.1186/s12882-018-0902-9.

4.

ABIN1 Determines Severity of Glomerulonephritis via Activation of Intrinsic Glomerular Inflammation.

Korte EA, Caster DJ, Barati MT, Tan M, Zheng S, Berthier CC, Brosius FC 3rd, Vieyra MB, Sheehan RM, Kosiewicz M, Wysoczynski M, Gaffney PM, Salant DJ, McLeish KR, Powell DW.

Am J Pathol. 2017 Dec;187(12):2799-2810. doi: 10.1016/j.ajpath.2017.08.018. Epub 2017 Sep 19.

5.

Endocytosis is required for exocytosis and priming of respiratory burst activity in human neutrophils.

Creed TM, Tandon S, Ward RA, McLeish KR.

Inflamm Res. 2017 Oct;66(10):891-899. doi: 10.1007/s00011-017-1070-2. Epub 2017 Jun 21.

PMID:
28638979
6.

Re-Examining Neutrophil Participation in GN.

Caster DJ, Powell DW, Miralda I, Ward RA, McLeish KR.

J Am Soc Nephrol. 2017 Aug;28(8):2275-2289. doi: 10.1681/ASN.2016121271. Epub 2017 Jun 15. Review. Erratum in: J Am Soc Nephrol. 2017 Oct;28(10 ):3129.

7.

Multiple Phenotypic Changes Define Neutrophil Priming.

Miralda I, Uriarte SM, McLeish KR.

Front Cell Infect Microbiol. 2017 May 29;7:217. doi: 10.3389/fcimb.2017.00217. eCollection 2017. Review.

8.

Frontline Science: Tumor necrosis factor-α stimulation and priming of human neutrophil granule exocytosis.

McLeish KR, Merchant ML, Creed TM, Tandon S, Barati MT, Uriarte SM, Ward RA.

J Leukoc Biol. 2017 Jul;102(1):19-29. doi: 10.1189/jlb.3HI0716-293RR. Epub 2017 Jan 17.

9.

Characterization of glomerular extracellular matrix by proteomic analysis of laser-captured microdissected glomeruli.

Hobeika L, Barati MT, Caster DJ, McLeish KR, Merchant ML.

Kidney Int. 2017 Feb;91(2):501-511. doi: 10.1016/j.kint.2016.09.044. Epub 2016 Dec 15.

10.

STAT3 Signaling in B Cells Is Critical for Germinal Center Maintenance and Contributes to the Pathogenesis of Murine Models of Lupus.

Ding C, Chen X, Dascani P, Hu X, Bolli R, Zhang HG, Mcleish KR, Yan J.

J Immunol. 2016 Jun 1;196(11):4477-86. doi: 10.4049/jimmunol.1502043. Epub 2016 Apr 25.

11.

Functionally and morphologically distinct populations of extracellular vesicles produced by human neutrophilic granulocytes.

Lőrincz ÁM, Schütte M, Timár CI, Veres DS, Kittel Á, McLeish KR, Merchant ML, Ligeti E.

J Leukoc Biol. 2015 Oct;98(4):583-9. doi: 10.1189/jlb.3VMA1014-514R. Epub 2015 May 18.

PMID:
25986013
12.

Changing the concepts of immune-mediated glomerular diseases through proteomics.

Caster DJ, Hobeika L, Klein JB, Powell DW, McLeish KR.

Proteomics Clin Appl. 2015 Dec;9(11-12):967-71. doi: 10.1002/prca.201400159. Epub 2015 Jun 17. Review.

13.

Baclofen, a GABABR agonist, ameliorates immune-complex mediated acute lung injury by modulating pro-inflammatory mediators.

Jin S, Merchant ML, Ritzenthaler JD, McLeish KR, Lederer ED, Torres-Gonzalez E, Fraig M, Barati MT, Lentsch AB, Roman J, Klein JB, Rane MJ.

PLoS One. 2015 Apr 7;10(4):e0121637. doi: 10.1371/journal.pone.0121637. eCollection 2015.

14.

Autoantibodies targeting glomerular annexin A2 identify patients with proliferative lupus nephritis.

Caster DJ, Korte EA, Merchant ML, Klein JB, Wilkey DW, Rovin BH, Birmingham DJ, Harley JB, Cobb BL, Namjou B, McLeish KR, Powell DW.

Proteomics Clin Appl. 2015 Dec;9(11-12):1012-20. doi: 10.1002/prca.201400175. Epub 2015 Jun 12.

15.

Mixed cryoglobulinemia and secondary membranoproliferative glomerulonephritis associated with ehrlichiosis.

Caster DJ, Summersgill JT, Paueksakon P, Massung RF, Shieh WJ, McLeish KR.

CEN Case Rep. 2014 Nov;3(2):178-182. doi: 10.1007/s13730-014-0113-6. Epub 2014 Mar 8.

16.

TAT-SNAP-23 treatment inhibits the priming of neutrophil functions contributing to shock and/or sepsis-induced extra-pulmonary acute lung injury.

Bai J, Tang L, Lomas-Neira J, Chen Y, McLeish KR, Uriarte SM, Chung CS, Ayala A.

Innate Immun. 2015 Jan;21(1):42-54. doi: 10.1177/1753425913516524. Epub 2014 Jan 3.

17.

The pore-forming toxin listeriolysin O is degraded by neutrophil metalloproteinase-8 and fails to mediate Listeria monocytogenes intracellular survival in neutrophils.

Arnett E, Vadia S, Nackerman CC, Oghumu S, Satoskar AR, McLeish KR, Uriarte SM, Seveau S.

J Immunol. 2014 Jan 1;192(1):234-44. doi: 10.4049/jimmunol.1301302. Epub 2013 Dec 6.

18.

ABIN1 dysfunction as a genetic basis for lupus nephritis.

Caster DJ, Korte EA, Nanda SK, McLeish KR, Oliver RK, G'sell RT, Sheehan RM, Freeman DW, Coventry SC, Kelly JA, Guthridge JM, James JA, Sivils KL, Alarcon-Riquelme ME, Scofield RH, Adrianto I, Gaffney PM, Stevens AM, Freedman BI, Langefeld CD, Tsao BP, Pons-Estel BA, Jacob CO, Kamen DL, Gilkeson GS, Brown EE, Alarcon GS, Edberg JC, Kimberly RP, Martin J, Merrill JT, Harley JB, Kaufman KM, Reveille JD, Anaya JM, Criswell LA, Vila LM, Petri M, Ramsey-Goldman R, Bae SC, Boackle SA, Vyse TJ, Niewold TB, Cohen P, Powell DW.

J Am Soc Nephrol. 2013 Nov;24(11):1743-54. doi: 10.1681/ASN.2013020148. Epub 2013 Aug 22.

19.

Technical note: proteomic approaches to fundamental questions about neutrophil biology.

McLeish KR, Merchant ML, Klein JB, Ward RA.

J Leukoc Biol. 2013 Oct;94(4):683-92. doi: 10.1189/jlb.1112591. Epub 2013 Mar 7. Review.

20.

Inhibition of neutrophil exocytosis ameliorates acute lung injury in rats.

Uriarte SM, Rane MJ, Merchant ML, Jin S, Lentsch AB, Ward RA, McLeish KR.

Shock. 2013 Mar;39(3):286-92. doi: 10.1097/SHK.0b013e318282c9a1.

21.

Exocytosis of neutrophil granule subsets and activation of prolyl isomerase 1 are required for respiratory burst priming.

McLeish KR, Uriarte SM, Tandon S, Creed TM, Le J, Ward RA.

J Innate Immun. 2013;5(3):277-89. doi: 10.1159/000345992. Epub 2013 Jan 26.

22.

Characteristics and outcomes in community-acquired versus hospital-acquired acute kidney injury.

Schissler MM, Zaidi S, Kumar H, Deo D, Brier ME, McLeish KR.

Nephrology (Carlton). 2013 Mar;18(3):183-7. doi: 10.1111/nep.12036.

PMID:
23336108
23.

Antibacterial effect of microvesicles released from human neutrophilic granulocytes.

Timár CI, Lorincz AM, Csépányi-Kömi R, Vályi-Nagy A, Nagy G, Buzás EI, Iványi Z, Kittel A, Powell DW, McLeish KR, Ligeti E.

Blood. 2013 Jan 17;121(3):510-8. doi: 10.1182/blood-2012-05-431114. Epub 2012 Nov 8.

24.

Olfactomedin 4 inhibits cathepsin C-mediated protease activities, thereby modulating neutrophil killing of Staphylococcus aureus and Escherichia coli in mice.

Liu W, Yan M, Liu Y, McLeish KR, Coleman WG Jr, Rodgers GP.

J Immunol. 2012 Sep 1;189(5):2460-7. doi: 10.4049/jimmunol.1103179. Epub 2012 Jul 27.

25.

Writing a first grant proposal.

Gomez-Cambronero J, Allen LA, Cathcart MK, Justement LB, Kovacs EJ, McLeish KR, Nauseef WM.

Nat Immunol. 2012 Jan 19;13(2):105-8. doi: 10.1038/ni.2183. No abstract available.

PMID:
22261956
26.

Granule exocytosis contributes to priming and activation of the human neutrophil respiratory burst.

Uriarte SM, Rane MJ, Luerman GC, Barati MT, Ward RA, Nauseef WM, McLeish KR.

J Immunol. 2011 Jul 1;187(1):391-400. doi: 10.4049/jimmunol.1003112. Epub 2011 Jun 3.

27.

Identification of phosphoproteins associated with human neutrophil granules following chemotactic peptide stimulation.

Luerman GC, Powell DW, Uriarte SM, Cummins TD, Merchant ML, Ward RA, McLeish KR.

Mol Cell Proteomics. 2011 Mar;10(3):M110.001552. doi: 10.1074/mcp.M110.001552. Epub 2010 Nov 19.

28.

Application of proteomics to neutrophil biology.

Luerman GC, Uriarte SM, Rane MJ, McLeish KR.

J Proteomics. 2010 Jan 3;73(3):552-61. doi: 10.1016/j.jprot.2009.06.013. Epub 2009 Jul 4. Review.

29.

Counterregulation of clathrin-mediated endocytosis by the actin and microtubular cytoskeleton in human neutrophils.

Uriarte SM, Jog NR, Luerman GC, Bhimani S, Ward RA, McLeish KR.

Am J Physiol Cell Physiol. 2009 Apr;296(4):C857-67. doi: 10.1152/ajpcell.00454.2008. Epub 2009 Jan 28.

30.

Anti-proteinase 3 antibodies both stimulate and prime human neutrophils.

Uriarte SM, McLeish KR, Ward RA.

Nephrol Dial Transplant. 2009 Apr;24(4):1150-7. doi: 10.1093/ndt/gfn580. Epub 2008 Oct 24.

PMID:
18952697
31.

Comparison of proteins expressed on secretory vesicle membranes and plasma membranes of human neutrophils.

Uriarte SM, Powell DW, Luerman GC, Merchant ML, Cummins TD, Jog NR, Ward RA, McLeish KR.

J Immunol. 2008 Apr 15;180(8):5575-81.

32.

Proteomic analysis defines altered cellular redox pathways and advanced glycation end-product metabolism in glomeruli of db/db diabetic mice.

Barati MT, Merchant ML, Kain AB, Jevans AW, McLeish KR, Klein JB.

Am J Physiol Renal Physiol. 2007 Oct;293(4):F1157-65. Epub 2007 Jul 3.

33.

Proteomic identification and immunolocalization of increased renal calbindin-D28k expression in OVE26 diabetic mice.

Thongboonkerd V, Zheng S, McLeish KR, Epstein PN, Klein JB.

Rev Diabet Stud. 2005 Spring;2(1):19-26. Epub 2005 May 10.

34.

Heat shock protein 27 regulates neutrophil chemotaxis and exocytosis through two independent mechanisms.

Jog NR, Jala VR, Ward RA, Rane MJ, Haribabu B, McLeish KR.

J Immunol. 2007 Feb 15;178(4):2421-8.

35.

The actin cytoskeleton regulates exocytosis of all neutrophil granule subsets.

Jog NR, Rane MJ, Lominadze G, Luerman GC, Ward RA, McLeish KR.

Am J Physiol Cell Physiol. 2007 May;292(5):C1690-700. Epub 2007 Jan 3.

36.

Proteomic analysis of human neutrophils.

Lominadze G, Ward RA, Klein JB, McLeish KR.

Methods Mol Biol. 2006;332:343-56.

PMID:
16878704
37.
38.

Proteomic analysis of human neutrophil granules.

Lominadze G, Powell DW, Luerman GC, Link AJ, Ward RA, McLeish KR.

Mol Cell Proteomics. 2005 Oct;4(10):1503-21. Epub 2005 Jun 28.

39.

Myeloid-related protein-14 is a p38 MAPK substrate in human neutrophils.

Lominadze G, Rane MJ, Merchant M, Cai J, Ward RA, McLeish KR.

J Immunol. 2005 Jun 1;174(11):7257-67.

40.

Gamma-amino butyric acid type B receptors stimulate neutrophil chemotaxis during ischemia-reperfusion.

Rane MJ, Gozal D, Butt W, Gozal E, Pierce WM Jr, Guo SZ, Wu R, Goldbart AD, Thongboonkerd V, McLeish KR, Klein JB.

J Immunol. 2005 Jun 1;174(11):7242-9.

41.

p38 MAPK/HSP25 signaling mediates cadmium-induced contraction of mesangial cells and renal glomeruli.

Hirano S, Sun X, DeGuzman CA, Ransom RF, McLeish KR, Smoyer WE, Shelden EA, Welsh MJ, Benndorf R.

Am J Physiol Renal Physiol. 2005 Jun;288(6):F1133-43. Epub 2005 Feb 1.

42.

Parathyroid hormone-mediated regulation of Na+-K+-ATPase requires ERK-dependent translocation of protein kinase Calpha.

Khundmiri SJ, Dean WL, McLeish KR, Lederer ED.

J Biol Chem. 2005 Mar 11;280(10):8705-13. Epub 2005 Jan 6.

43.

Defining mitogen-activated protein kinase pathways with mass spectrometry-based approaches.

Powell DW, Pierce WM, McLeish KR.

Mass Spectrom Rev. 2005 Nov-Dec;24(6):847-64. Review.

PMID:
15619233
44.

Methylglyoxal: a stimulus to neutrophil oxygen radical production in chronic renal failure?

Ward RA, McLeish KR.

Nephrol Dial Transplant. 2004 Jul;19(7):1702-7. Epub 2004 May 18.

PMID:
15150351
45.

Alterations in the renal elastin-elastase system in type 1 diabetic nephropathy identified by proteomic analysis.

Thongboonkerd V, Barati MT, McLeish KR, Benarafa C, Remold-O'Donnell E, Zheng S, Rovin BH, Pierce WM, Epstein PN, Klein JB.

J Am Soc Nephrol. 2004 Mar;15(3):650-62.

46.

Urinary proteomics and biomarker discovery for glomerular diseases.

Thongboonkerd V, Klein JB, Jevans AW, McLeish KR.

Contrib Nephrol. 2004;141:292-307. Review. No abstract available.

PMID:
14650240
47.

Proteomic approach to identification of novel kinase substrates in mesangial cells.

Barati MT, Powell DW, McLeish KR.

Contrib Nephrol. 2004;141:231-44. Review. No abstract available.

PMID:
14650236
48.

Proteomics and diabetic nephropathy.

Thongboonkerd V, Barati MT, McLeish KR, Pierce WM, Epstein PN, Klein JB.

Contrib Nephrol. 2004;141:142-54. Review. No abstract available.

PMID:
14650230
49.

MAPK-activated protein kinase-2 participates in p38 MAPK-dependent and ERK-dependent functions in human neutrophils.

Coxon PY, Rane MJ, Uriarte S, Powell DW, Singh S, Butt W, Chen Q, McLeish KR.

Cell Signal. 2003 Nov;15(11):993-1001.

PMID:
14499342
50.

Proteomic identification of 14-3-3zeta as a mitogen-activated protein kinase-activated protein kinase 2 substrate: role in dimer formation and ligand binding.

Powell DW, Rane MJ, Joughin BA, Kalmukova R, Hong JH, Tidor B, Dean WL, Pierce WM, Klein JB, Yaffe MB, McLeish KR.

Mol Cell Biol. 2003 Aug;23(15):5376-87.

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