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Items: 27

1.

Dissecting Human Gene Functions Regulating Islet Development With Targeted Gene Transduction.

Pauerstein PT, Sugiyama T, Stanley SE, McLean GW, Wang J, Martín MG, Kim SK.

Diabetes. 2015 Aug;64(8):3037-49. doi: 10.2337/db15-0042. Epub 2015 Apr 21.

2.

Reconstituting pancreas development from purified progenitor cells reveals genes essential for islet differentiation.

Sugiyama T, Benitez CM, Ghodasara A, Liu L, McLean GW, Lee J, Blauwkamp TA, Nusse R, Wright CV, Gu G, Kim SK.

Proc Natl Acad Sci U S A. 2013 Jul 30;110(31):12691-6. doi: 10.1073/pnas.1304507110. Epub 2013 Jul 12.

3.

Specification of Drosophila corpora cardiaca neuroendocrine cells from mesoderm is regulated by Notch signaling.

Park S, Bustamante EL, Antonova J, McLean GW, Kim SK.

PLoS Genet. 2011 Aug;7(8):e1002241. doi: 10.1371/journal.pgen.1002241. Epub 2011 Aug 25.

4.

Continuous subcutaneous pramlintide infusion therapy in patients with type 1 diabetes: observations from a pilot study.

Huffman DM, McLean GW, Seagrove MA.

Endocr Pract. 2009 Nov-Dec;15(7):689-95. doi: 10.4158/EP09044.ORR1.

PMID:
19546056
5.

Mammary epithelial-specific disruption of the focal adhesion kinase blocks mammary tumor progression.

Lahlou H, Sanguin-Gendreau V, Zuo D, Cardiff RD, McLean GW, Frame MC, Muller WJ.

Proc Natl Acad Sci U S A. 2007 Dec 18;104(51):20302-7. Epub 2007 Dec 3.

6.

Menin controls growth of pancreatic beta-cells in pregnant mice and promotes gestational diabetes mellitus.

Karnik SK, Chen H, McLean GW, Heit JJ, Gu X, Zhang AY, Fontaine M, Yen MH, Kim SK.

Science. 2007 Nov 2;318(5851):806-9.

7.

Focal adhesion kinase controls actin assembly via a FERM-mediated interaction with the Arp2/3 complex.

Serrels B, Serrels A, Brunton VG, Holt M, McLean GW, Gray CH, Jones GE, Frame MC.

Nat Cell Biol. 2007 Sep;9(9):1046-56. Epub 2007 Aug 26.

PMID:
17721515
8.

Conserved markers of fetal pancreatic epithelium permit prospective isolation of islet progenitor cells by FACS.

Sugiyama T, Rodriguez RT, McLean GW, Kim SK.

Proc Natl Acad Sci U S A. 2007 Jan 2;104(1):175-80. Epub 2006 Dec 26.

9.

Menin regulates pancreatic islet growth by promoting histone methylation and expression of genes encoding p27Kip1 and p18INK4c.

Karnik SK, Hughes CM, Gu X, Rozenblatt-Rosen O, McLean GW, Xiong Y, Meyerson M, Kim SK.

Proc Natl Acad Sci U S A. 2005 Oct 11;102(41):14659-64. Epub 2005 Sep 29.

10.

The role of focal-adhesion kinase in cancer - a new therapeutic opportunity.

McLean GW, Carragher NO, Avizienyte E, Evans J, Brunton VG, Frame MC.

Nat Rev Cancer. 2005 Jul;5(7):505-15. Review.

PMID:
16069815
11.

Specific deletion of focal adhesion kinase suppresses tumor formation and blocks malignant progression.

McLean GW, Komiyama NH, Serrels B, Asano H, Reynolds L, Conti F, Hodivala-Dilke K, Metzger D, Chambon P, Grant SG, Frame MC.

Genes Dev. 2004 Dec 15;18(24):2998-3003.

12.

Focal adhesion kinase as a potential target in oncology.

McLean GW, Avizienyte E, Frame MC.

Expert Opin Pharmacother. 2003 Feb;4(2):227-34. Review.

PMID:
12562313
13.

Src-induced de-regulation of E-cadherin in colon cancer cells requires integrin signalling.

Avizienyte E, Wyke AW, Jones RJ, McLean GW, Westhoff MA, Brunton VG, Frame MC.

Nat Cell Biol. 2002 Aug;4(8):632-8.

PMID:
12134161
14.

Decreased focal adhesion kinase suppresses papilloma formation during experimental mouse skin carcinogenesis.

McLean GW, Brown K, Arbuckle MI, Wyke AW, Pikkarainen T, Ruoslahti E, Frame MC.

Cancer Res. 2001 Dec 1;61(23):8385-9.

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17.

The catalytic activity of the Src family kinases is required to disrupt cadherin-dependent cell-cell contacts.

Owens DW, McLean GW, Wyke AW, Paraskeva C, Parkinson EK, Frame MC, Brunton VG.

Mol Biol Cell. 2000 Jan;11(1):51-64.

18.

The catalytic subunit of the DNA polymerase of herpes simplex virus type 1 interacts specifically with the C terminus of the UL8 component of the viral helicase-primase complex.

Marsden HS, McLean GW, Barnard EC, Francis GJ, MacEachran K, Murphy M, McVey G, Cross A, Abbotts AP, Stow ND.

J Virol. 1997 Sep;71(9):6390-7.

19.

The herpes simplex virus type 1 origin-binding protein interacts specifically with the viral UL8 protein.

McLean GW, Abbotts AP, Parry ME, Marsden HS, Stow ND.

J Gen Virol. 1994 Oct;75 ( Pt 10):2699-706.

PMID:
7931156
20.

Rapid attachment of a helper T cell epitope to branched peptides by fragment condensation to give enhanced immunogenicity.

McLean GW, Cross AM, Munns MS, Marsden HS.

J Immunol Methods. 1992 Oct 19;155(1):113-20.

PMID:
1383344
21.

Advantages of branched peptides in serodiagnosis. Detection of HIV-specific antibodies and the use of glycine spacers to increase sensitivity.

Marsden HS, Owsianka AM, Graham S, McLean GW, Robertson CA, Subak-Sharpe JH.

J Immunol Methods. 1992 Feb 14;147(1):65-72.

PMID:
1541843
22.

Generation of anti-peptide and anti-protein sera. Effect of peptide presentation on immunogenicity.

McLean GW, Owsianka AM, Subak-Sharpe JH, Marsden HS.

J Immunol Methods. 1991 Mar 21;137(2):149-57.

PMID:
1707429
23.

Evaluation of provocative tests in suspected medullary carcinoma of the thyroid:heterogeneity of calcitonin responses to calcium and pentagastrin.

McLean GW, Rabin D, Moore L, Deftos LJ, Lorber D, McKenna TJ.

Metabolism. 1984 Sep;33(9):790-6.

PMID:
6472115
24.

Autonomous hyperprolactinemia in tuberous sclerosis.

Bloomgarden ZT, McLean GW, Rabin D.

Arch Intern Med. 1981 Oct;141(11):1513-5.

PMID:
7197143
25.

Titration of malate dehydrogenase with 2-hydroxy-5-nitrobenzyl bromide.

Schellenberg KA, McLean GW.

Biochim Biophys Acta. 1969;191(3):727-8. No abstract available.

PMID:
5391645
26.

Indolenines. Reduction by a dihydropyridine and addition to thiols.

Schellenberg KA, McLean GW, Lipton HL, Lietman PS.

J Am Chem Soc. 1967 Apr 12;89(8):1948-50. No abstract available.

PMID:
6040526
27.

Reactions of an indolenine salt as a possible model for dehydrogenase enzymes.

Schellenberg KA, McLean GW.

J Am Chem Soc. 1966 Mar 5;88(5):1077-9. No abstract available.

PMID:
5903969

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