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Items: 6

1.

PPT1 promotes tumor growth and is the molecular target of chloroquine derivatives in cancer.

Rebecca VW, Nicastri MC, Fennelly C, Chude CI, Barber-Rotenberg JS, Ronghe A, McAfee Q, McLaughlin NP, Zhang G, Goldman AR, Ojha R, Piao S, Noguera-Ortega E, Martorella A, Alicea GM, Lee JJ, Schuchter LM, Xu X, Herlyn M, Marmorstein R, Gimotty PA, Speicher DW, Winkler JD, Amaravadi RK.

Cancer Discov. 2018 Nov 15. pii: CD-18-0706. doi: 10.1158/2159-8290.CD-18-0706. [Epub ahead of print]

PMID:
30442709
2.

Chemical synthesis of febrifugine and analogues.

Smullen S, McLaughlin NP, Evans P.

Bioorg Med Chem. 2018 May 15;26(9):2199-2220. doi: 10.1016/j.bmc.2018.04.027. Epub 2018 Apr 12. Review.

PMID:
29681487
3.

The Suramin Derivative NF449 Interacts with the 5-fold Vertex of the Enterovirus A71 Capsid to Prevent Virus Attachment to PSGL-1 and Heparan Sulfate.

Nishimura Y, McLaughlin NP, Pan J, Goldstein S, Hafenstein S, Shimizu H, Winkler JD, Bergelson JM.

PLoS Pathog. 2015 Oct 2;11(10):e1005184. doi: 10.1371/journal.ppat.1005184. eCollection 2015 Oct.

4.

The chemistry and biology of febrifugine and halofuginone.

McLaughlin NP, Evans P, Pines M.

Bioorg Med Chem. 2014 Apr 1;22(7):1993-2004. doi: 10.1016/j.bmc.2014.02.040. Epub 2014 Mar 1. Review.

PMID:
24650700
5.

Dihydroxylation of vinyl sulfones: stereoselective synthesis of (+)- and (-)-febrifugine and halofuginone.

McLaughlin NP, Evans P.

J Org Chem. 2010 Jan 15;75(2):518-21. doi: 10.1021/jo902396m.

PMID:
20000346
6.

Xanthoderma: an unusual presentation of hypothyroidism.

al-Jubouri MA, Coombes EJ, Young RM, McLaughlin NP.

J Clin Pathol. 1994 Sep;47(9):850-1.

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