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Items: 7


Insights into AMS/PCAT transporters from biochemical and structural characterization of a double Glycine motif protease.

Bobeica SC, Dong SH, Huo L, Mazo N, McLaughlin MI, Jiménez-Osés G, Nair SK, van der Donk WA.

Elife. 2019 Jan 14;8. pii: e42305. doi: 10.7554/eLife.42305.


Stereospecific Radical-Mediated B12-Dependent Methyl Transfer by the Fosfomycin Biosynthesis Enzyme Fom3.

McLaughlin MI, van der Donk WA.

Biochemistry. 2018 Aug 21;57(33):4967-4971. doi: 10.1021/acs.biochem.8b00616. Epub 2018 Jul 10.


Crystallographic snapshots of sulfur insertion by lipoyl synthase.

McLaughlin MI, Lanz ND, Goldman PJ, Lee KH, Booker SJ, Drennan CL.

Proc Natl Acad Sci U S A. 2016 Aug 23;113(34):9446-50. doi: 10.1073/pnas.1602486113. Epub 2016 Aug 9.


Structure of Quinolinate Synthase from Pyrococcus horikoshii in the Presence of Its Product, Quinolinic Acid.

Esakova OA, Silakov A, Grove TL, Saunders AH, McLaughlin MI, Yennawar NH, Booker SJ.

J Am Chem Soc. 2016 Jun 15;138(23):7224-7. doi: 10.1021/jacs.6b02708. Epub 2016 Jun 2.


Allosteric Inhibition of Human Ribonucleotide Reductase by dATP Entails the Stabilization of a Hexamer.

Ando N, Li H, Brignole EJ, Thompson S, McLaughlin MI, Page JE, Asturias FJ, Stubbe J, Drennan CL.

Biochemistry. 2016 Jan 19;55(2):373-81. doi: 10.1021/acs.biochem.5b01207. Epub 2016 Jan 4.


X-ray structure of an AdoMet radical activase reveals an anaerobic solution for formylglycine posttranslational modification.

Goldman PJ, Grove TL, Sites LA, McLaughlin MI, Booker SJ, Drennan CL.

Proc Natl Acad Sci U S A. 2013 May 21;110(21):8519-24. doi: 10.1073/pnas.1302417110. Epub 2013 May 6.


Structural basis for methyl transfer by a radical SAM enzyme.

Boal AK, Grove TL, McLaughlin MI, Yennawar NH, Booker SJ, Rosenzweig AC.

Science. 2011 May 27;332(6033):1089-92. doi: 10.1126/science.1205358. Epub 2011 Apr 28.

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