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Items: 27

1.

Leveraging Colloidal Aggregation for Drug-Rich Nanoparticle Formulations.

Ganesh AN, Logie J, McLaughlin CK, Barthel BL, Koch TH, Shoichet BK, Shoichet MS.

Mol Pharm. 2017 Jun 5;14(6):1852-1860. doi: 10.1021/acs.molpharmaceut.6b01015. Epub 2017 May 19.

2.

A New Spin on Antibody-Drug Conjugates: Trastuzumab-Fulvestrant Colloidal Drug Aggregates Target HER2-Positive Cells.

Ganesh AN, McLaughlin CK, Duan D, Shoichet BK, Shoichet MS.

ACS Appl Mater Interfaces. 2017 Apr 12;9(14):12195-12202. doi: 10.1021/acsami.6b15987. Epub 2017 Mar 28.

3.

Internal Structure and Preferential Protein Binding of Colloidal Aggregates.

Duan D, Torosyan H, Elnatan D, McLaughlin CK, Logie J, Shoichet MS, Agard DA, Shoichet BK.

ACS Chem Biol. 2017 Jan 20;12(1):282-290. doi: 10.1021/acschembio.6b00791. Epub 2016 Dec 16.

4.

Encapsulation-free controlled release: Electrostatic adsorption eliminates the need for protein encapsulation in PLGA nanoparticles.

Pakulska MM, Elliott Donaghue I, Obermeyer JM, Tuladhar A, McLaughlin CK, Shendruk TN, Shoichet MS.

Sci Adv. 2016 May 27;2(5):e1600519. doi: 10.1126/sciadv.1600519. eCollection 2016 May.

5.

Stable Colloidal Drug Aggregates Catch and Release Active Enzymes.

McLaughlin CK, Duan D, Ganesh AN, Torosyan H, Shoichet BK, Shoichet MS.

ACS Chem Biol. 2016 Apr 15;11(4):992-1000. doi: 10.1021/acschembio.5b00806. Epub 2016 Jan 15.

6.

Innovative use of the taxol binding peptide overcomes key challenges of stable and high drug loading in polymeric nanomicelles.

Logie J, McLaughlin CK, Tam RY, Shoichet MS.

Chem Commun (Camb). 2015 Aug 4;51(60):12000-3. doi: 10.1039/c5cc04282h.

PMID:
26121243
7.

Dynamic behavior of DNA cages anchored on spherically supported lipid bilayers.

Conway JW, Madwar C, Edwardson TG, McLaughlin CK, Fahkoury J, Lennox RB, Sleiman HF.

J Am Chem Soc. 2014 Sep 17;136(37):12987-97. doi: 10.1021/ja506095n. Epub 2014 Sep 8.

PMID:
25140890
8.

Colloidal drug formulations can explain "bell-shaped" concentration-response curves.

Owen SC, Doak AK, Ganesh AN, Nedyalkova L, McLaughlin CK, Shoichet BK, Shoichet MS.

ACS Chem Biol. 2014 Mar 21;9(3):777-84. doi: 10.1021/cb4007584. Epub 2014 Jan 15.

9.

Development and characterization of gene silencing DNA cages.

Fakhoury JJ, McLaughlin CK, Edwardson TW, Conway JW, Sleiman HF.

Biomacromolecules. 2014 Jan 13;15(1):276-82. doi: 10.1021/bm401532n. Epub 2013 Dec 26.

PMID:
24328173
10.

Site-specific positioning of dendritic alkyl chains on DNA cages enables their geometry-dependent self-assembly.

Edwardson TG, Carneiro KM, McLaughlin CK, Serpell CJ, Sleiman HF.

Nat Chem. 2013 Oct;5(10):868-75. doi: 10.1038/nchem.1745. Epub 2013 Sep 1.

PMID:
24056344
11.

DNA nanostructure serum stability: greater than the sum of its parts.

Conway JW, McLaughlin CK, Castor KJ, Sleiman H.

Chem Commun (Camb). 2013 Feb 11;49(12):1172-4. doi: 10.1039/c2cc37556g.

PMID:
23287884
12.

Application of a fluorescent C-linked phenolic purine adduct for selective N7-metalation of DNA.

Omumi A, McLaughlin CK, Ben-Israel D, Manderville RA.

J Phys Chem B. 2012 May 31;116(21):6158-65. doi: 10.1021/jp303138s. Epub 2012 May 18.

PMID:
22607044
13.

Three-dimensional organization of block copolymers on "DNA-minimal" scaffolds.

McLaughlin CK, Hamblin GD, Hänni KD, Conway JW, Nayak MK, Carneiro KM, Bazzi HS, Sleiman HF.

J Am Chem Soc. 2012 Mar 7;134(9):4280-6. doi: 10.1021/ja210313p. Epub 2012 Feb 22.

PMID:
22309245
14.

Supramolecular DNA assembly.

McLaughlin CK, Hamblin GD, Sleiman HF.

Chem Soc Rev. 2011 Dec;40(12):5647-56. doi: 10.1039/c1cs15253j. Epub 2011 Oct 19. Review.

PMID:
22012315
15.

A facile, modular and high yield method to assemble three-dimensional DNA structures.

McLaughlin CK, Hamblin GD, Aldaye FA, Yang H, Sleiman HF.

Chem Commun (Camb). 2011 Aug 21;47(31):8925-7. doi: 10.1039/c1cc11726b. Epub 2011 Jul 11.

PMID:
21748162
16.

Self-assembly of metal-DNA triangles and DNA nanotubes with synthetic junctions.

Yang H, Lo PK, McLaughlin CK, Hamblin GD, Aldaye FA, Sleiman HF.

Methods Mol Biol. 2011;749:33-47. doi: 10.1007/978-1-61779-142-0_3.

PMID:
21674363
17.

Chiral metal-DNA four-arm junctions and metalated nanotubular structures.

Yang H, Altvater F, de Bruijn AD, McLaughlin CK, Lo PK, Sleiman HF.

Angew Chem Int Ed Engl. 2011 May 9;50(20):4620-3. doi: 10.1002/anie.201007403. Epub 2011 Apr 26. No abstract available.

PMID:
21523864
18.

Loading and selective release of cargo in DNA nanotubes with longitudinal variation.

Lo PK, Karam P, Aldaye FA, McLaughlin CK, Hamblin GD, Cosa G, Sleiman HF.

Nat Chem. 2010 Apr;2(4):319-28. doi: 10.1038/nchem.575. Epub 2010 Mar 14.

PMID:
21124515
19.

Stable gold nanoparticle conjugation to internal DNA positions: facile generation of discrete gold nanoparticle-DNA assemblies.

Wen Y, McLaughlin CK, Lo PK, Yang H, Sleiman HF.

Bioconjug Chem. 2010 Aug 18;21(8):1413-6. doi: 10.1021/bc100160k.

PMID:
20666441
20.

Templated ligand environments for the selective incorporation of different metals into DNA.

Yang H, Rys AZ, McLaughlin CK, Sleiman HF.

Angew Chem Int Ed Engl. 2009;48(52):9919-23. doi: 10.1002/anie.200904186. No abstract available.

PMID:
19924748
21.

Metal-nucleic acid cages.

Yang H, McLaughlin CK, Aldaye FA, Hamblin GD, Rys AZ, Rouiller I, Sleiman HF.

Nat Chem. 2009 Aug;1(5):390-6. doi: 10.1038/nchem.290. Epub 2009 Jul 24.

PMID:
21378893
22.

Modular construction of DNA nanotubes of tunable geometry and single- or double-stranded character.

Aldaye FA, Lo PK, Karam P, McLaughlin CK, Cosa G, Sleiman HF.

Nat Nanotechnol. 2009 Jun;4(6):349-52. doi: 10.1038/nnano.2009.72. Epub 2009 Apr 12.

PMID:
19498394
23.

Oxidation of a biomarker for phenol carcinogen exposure: expanding the redox chemistry of 2'-deoxyguanosine.

Weishar JL, McLaughlin CK, Baker M, Gabryelski W, Manderville RA.

Org Lett. 2008 May 1;10(9):1839-42. doi: 10.1021/ol8004694. Epub 2008 Apr 8.

PMID:
18393513
24.

Computational and experimental evidence for the structural preference of phenolic C-8 purine adducts.

Millen AL, McLaughlin CK, Sun KM, Manderville RA, Wetmore SD.

J Phys Chem A. 2008 Apr 24;112(16):3742-53. doi: 10.1021/jp712058a. Epub 2008 Apr 1.

PMID:
18376879
25.

Biomarkers for phenol carcinogen exposure act as pH-sensing fluorescent probes.

Sun KM, McLaughlin CK, Lantero DR, Manderville RA.

J Am Chem Soc. 2007 Feb 21;129(7):1894-5. Epub 2007 Jan 27. No abstract available.

PMID:
17256942
26.

Regioselective bond cleavage in the dissociative electron transfer to benzyl thiocyanates: the role of radical/ion pair formation.

Hamed EM, Doai H, McLaughlin CK, Houmam A.

J Am Chem Soc. 2006 May 24;128(20):6595-604.

PMID:
16704259
27.

Conformational properties of a phototautomerizable nucleoside biomarker for phenolic carcinogen exposure.

McLaughlin CK, Lantero DR, Manderville RA.

J Phys Chem A. 2006 May 18;110(19):6224-30.

PMID:
16686455

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