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Diffuse optical spectroscopic imaging for the investigation of human lactation physiology: a case study on mammary involution.

Bosschaart N, Leproux A, Abdalsalam O, Chen WP, McLaren CE, Tromberg BJ, O'Sullivan TD.

J Biomed Opt. 2019 May;24(5):1-8. doi: 10.1117/1.JBO.24.5.056006.


Bivariate mixture models for the joint distribution of repeated serum ferritin and transferrin saturation measured 12 years apart in a cohort of healthy middle-aged Australians.

McLaren CE, Chen WP, Bertalli NA, Delatycki MB, Giles GG, English DR, Hopper JL, Allen KJ, Gurrin LC.

PLoS One. 2019 Mar 26;14(3):e0214196. doi: 10.1371/journal.pone.0214196. eCollection 2019.


Cirrhosis in Hemochromatosis: Independent Risk Factors in 368 HFE p.C282Y Homozygotes.

Barton JC, McLaren CE, Chen WP, Ramm GA, Anderson GJ, Powell LW, Subramaniam VN, Adams PC, Phatak PD, Gurrin LC, Phillips JD, Parker CJ, Emond MJ, McLaren GD.

Ann Hepatol. 2018 Aug 24;17(5):871-879. doi: 10.5604/01.3001.0012.3169.


Non-invasive Dual-Channel Broadband Diffuse Optical Spectroscopy of Massive Hemorrhage and Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) in Swine.

Lam JH, O'Sullivan TD, Park TS, Choi JH, Warren RV, Chen WP, McLaren CE, Cancio LC, Batchinsky AI, Tromberg BJ.

Mil Med. 2018 Mar 1;183(suppl_1):150-156. doi: 10.1093/milmed/usx163.



Brissot P, Pietrangelo A, Adams PC, de Graaff B, McLaren CE, Loréal O.

Nat Rev Dis Primers. 2018 Apr 5;4:18016. doi: 10.1038/nrdp.2018.16. Review.


Bolstering the Number and Function of HSV-1-Specific CD8+ Effector Memory T Cells and Tissue-Resident Memory T Cells in Latently Infected Trigeminal Ganglia Reduces Recurrent Ocular Herpes Infection and Disease.

Khan AA, Srivastava R, Chentoufi AA, Kritzer E, Chilukuri S, Garg S, Yu DC, Vahed H, Huang L, Syed SA, Furness JN, Tran TT, Anthony NB, McLaren CE, Sidney J, Sette A, Noelle RJ, BenMohamed L.

J Immunol. 2017 Jul 1;199(1):186-203. doi: 10.4049/jimmunol.1700145. Epub 2017 May 24.


Sample size and power determination when limited preliminary information is available.

McLaren CE, Chen WP, O'Sullivan TD, Gillen DL, Su MY, Chen JH, Tromberg BJ.

BMC Med Res Methodol. 2017 Apr 26;17(1):75. doi: 10.1186/s12874-017-0329-1.


Can Radiologists Predict the Presence of Ductal Carcinoma In Situ and Invasive Breast Cancer?

Aminololama-Shakeri S, Flowers CI, McLaren CE, Wisner DJ, de Guzman J, Campbell JE, Bassett LW, Ojeda-Fournier H, Gerlach K, Hargreaves J, Elson SL, Retallack H, Joe BN, Feig SA, Wells CJ; ATHENA Breast Health Initiative.

AJR Am J Roentgenol. 2017 Apr;208(4):933-939. doi: 10.2214/AJR.16.16073. Epub 2017 Feb 15.



McLaren GD, Barton JC, Ramm GA, Emond MJ, Subramaniam VN, Phatak PD, Adams PC, Powell LW, Gurrin LC, Anderson GJ, McLaren CE.

Hepatology. 2017 Mar;65(3):1072-1073. doi: 10.1002/hep.29002. Epub 2017 Feb 3. No abstract available. Erratum in: Hepatology. 2017 Jun;65(6):2136.


GNPAT p.D519G is independently associated with markedly increased iron stores in HFE p.C282Y homozygotes.

Barton JC, Chen WP, Emond MJ, Phatak PD, Subramaniam VN, Adams PC, Gurrin LC, Anderson GJ, Ramm GA, Powell LW, Allen KJ, Phillips JD, Parker CJ, McLaren GD, McLaren CE.

Blood Cells Mol Dis. 2017 Mar;63:15-20. doi: 10.1016/j.bcmd.2016.11.009. Epub 2016 Nov 12.


HFE p.C282Y homozygosity predisposes to rapid serum ferritin rise after menopause: A genotype-stratified cohort study of hemochromatosis in Australian women.

Warne CD, Zaloumis SG, Bertalli NA, Delatycki MB, Nicoll AJ, McLaren CE, Hopper JL, Giles GG, Anderson GJ, Olynyk JK, Powell LW, Allen KJ, Gurrin LC; HealthIron Study Investigators.

J Gastroenterol Hepatol. 2017 Apr;32(4):797-802. doi: 10.1111/jgh.13621.


EUS-guided portal pressure gradient measurement with a simple novel device: a human pilot study.

Huang JY, Samarasena JB, Tsujino T, Lee J, Hu KQ, McLaren CE, Chen WP, Chang KJ.

Gastrointest Endosc. 2017 May;85(5):996-1001. doi: 10.1016/j.gie.2016.09.026. Epub 2016 Sep 29.


The D519G Polymorphism of Glyceronephosphate O-Acyltransferase Is a Risk Factor for Familial Porphyria Cutanea Tarda.

Farrell CP, Overbey JR, Naik H, Nance D, McLaren GD, McLaren CE, Zhou L, Desnick RJ, Parker CJ, Phillips JD.

PLoS One. 2016 Sep 23;11(9):e0163322. doi: 10.1371/journal.pone.0163322. eCollection 2016.


Differential diagnosis of breast masses in South Korean premenopausal women using diffuse optical spectroscopic imaging.

Leproux A, Kim YM, Min JW, McLaren CE, Chen WP, O'Sullivan TD, Lee SH, Chung PS, Tromberg BJ.

J Biomed Opt. 2016 Jul 1;21(7):74001. doi: 10.1117/1.JBO.21.7.074001.



McLaren CE, Barton JC, Subramaniam VN, Ramm GA, Phatak PD, Emond MJ, Gurrin LC, Adams PC, Powell LW, Anderson GJ, McLaren GD.

Hepatology. 2016 Jun;63(6):2058-60. doi: 10.1002/hep.28479. Epub 2016 Mar 15. No abstract available.



McLaren CE, Barton JC, Phatak PD, Emond MJ, Subramaniam VN, Gurrin LC, Adams PC, Powell LW, Ramm GA, Anderson GJ, McLaren GD.

Hepatology. 2016 Jun;63(6):2056-7. doi: 10.1002/hep.28260. Epub 2015 Dec 18. No abstract available.


Impact of positional difference on the measurement of breast density using MRI.

Chen JH, Chan S, Tang YT, Hon JS, Tseng PC, Cheriyan AT, Shah NR, Yeh DC, Lee SK, Chen WP, McLaren CE, Su MY.

Med Phys. 2015 May;42(5):2268-75. doi: 10.1118/1.4917083.


Reply: To PMID 25605615.

McLaren CE, Emond MJ, Subramaniam VN, Phatak PD, Barton JC, Adams PC, Powell LW, Gurrin LC, Ramm GA, Anderson GJ, McLaren GD.

Hepatology. 2015 Dec;62(6):1918-9. doi: 10.1002/hep.27851. Epub 2015 Jun 3. No abstract available.


Exome sequencing in HFE C282Y homozygous men with extreme phenotypes identifies a GNPAT variant associated with severe iron overload.

McLaren CE, Emond MJ, Subramaniam VN, Phatak PD, Barton JC, Adams PC, Goh JB, McDonald CJ, Powell LW, Gurrin LC, Allen KJ, Nickerson DA, Louie T, Ramm GA, Anderson GJ, McLaren GD.

Hepatology. 2015 Aug;62(2):429-39. doi: 10.1002/hep.27711. Epub 2015 Mar 18.


Combined benefit of prediction and treatment: a criterion for evaluating clinical prediction models.

Billheimer D, Gerner EW, McLaren CE, LaFleur B.

Cancer Inform. 2014 Oct 5;13(Suppl 2):93-103. doi: 10.4137/CIN.S13780. eCollection 2014.


Natural history of HFE simple heterozygosity for C282Y and H63D: a prospective 12-year study.

Zaloumis SG, Allen KJ, Bertalli NA, Turkovic L, Delatycki MB, Nicoll AJ, McLaren CE, English DR, Hopper JL, Giles GG, Anderson GJ, Olynyk JK, Powell LW, Gurrin LC; HealthIron Study Investigators.

J Gastroenterol Hepatol. 2015 Apr;30(4):719-25. doi: 10.1111/jgh.12804.


A randomized, double-blind, placebo-controlled phase II clinical trial of lovastatin for various endpoints of melanoma pathobiology.

Linden KG, Leachman SA, Zager JS, Jakowatz JG, Viner JL, McLaren CE, Barr RJ, Carpenter PM, Chen WP, Elmets CA, Tangrea JA, Lim SJ, Cochran AJ, Meyskens FL Jr.

Cancer Prev Res (Phila). 2014 May;7(5):496-504. doi: 10.1158/1940-6207.CAPR-13-0189. Epub 2014 Mar 10.


Generation of "virtual" control groups for single arm prostate cancer adjuvant trials.

Jia Z, Lilly MB, Koziol JA, Chen X, Xia XQ, Wang Y, Skarecky D, Sutton M, Sawyers A, Ruckle H, Carpenter PM, Wang-Rodriguez J, Jiang J, Deng M, Pan C, Zhu JG, McLaren CE, Gurley MJ, Lee C, McClelland M, Ahlering T, Kattan MW, Mercola D.

PLoS One. 2014 Jan 21;9(1):e85010. doi: 10.1371/journal.pone.0085010. eCollection 2014.


Elevated transferrin saturation, health-related quality of life and telomere length.

Mainous AG 3rd, Wright RU, Hulihan MM, Twal WO, McLaren CE, Diaz VA, McLaren GD, Argraves WS, Grant AM.

Biometals. 2014 Feb;27(1):135-41. doi: 10.1007/s10534-013-9693-4. Epub 2013 Dec 15.


Impact of factors affecting the residual tumor size diagnosed by MRI following neoadjuvant chemotherapy in comparison to pathology.

Chen JH, Bahri S, Mehta RS, Carpenter PM, McLaren CE, Chen WP, Fwu PT, Hsiang DJ, Lane KT, Butler JA, Su MY.

J Surg Oncol. 2014 Feb;109(2):158-67. doi: 10.1002/jso.23470. Epub 2013 Oct 28.


Determination of optimal replicate number for validation of imprecision using fluorescence cell-based assays: proposed practical method.

Davis BH, McLaren CE, Carcio AJ, Wong L, Hedley BD, Keeney M, Curtis A, Culp NB.

Cytometry B Clin Cytom. 2013 Sep-Oct;84(5):329-37. doi: 10.1002/cyto.b.21116.


Effect of taxane-based neoadjuvant chemotherapy on fibroglandular tissue volume and percent breast density in the contralateral normal breast evaluated by 3T MR.

Chen JH, Pan WF, Kao J, Lu J, Chen LK, Kuo CC, Chang CK, Chen WP, McLaren CE, Bahri S, Mehta RS, Su MY.

NMR Biomed. 2013 Dec;26(12):1705-13. doi: 10.1002/nbm.3006. Epub 2013 Aug 12.


Determination of optimal replicate number for validation of imprecision using fluorescence cell based assays: Proposed practical method.

Davis BH, McLaren CE, Carcio AJ, Wong L, Hedley BD, Keeney M, Curtis A, Culp NB.

Cytometry B Clin Cytom. 2013 Jul 19. doi: 10.1002/cytob.21116. [Epub ahead of print]


HFE mutations in Caucasian participants of the Hemochromatosis and Iron Overload Screening study with serum ferritin level <1000 µg/L.

Adams PC, McLaren CE, Speechley M, McLaren GD, Barton JC, Eckfeldt JH.

Can J Gastroenterol. 2013 Jul;27(7):390-2.


Correlation of endogenous hormonal levels, fibroglandular tissue volume and percent density measured using 3D MRI during one menstrual cycle.

Chen JH, Chen WP, Chan S, Yeh DC, Su MY, McLaren CE.

Ann Oncol. 2013 Sep;24(9):2329-35. doi: 10.1093/annonc/mdt158. Epub 2013 May 9.


Telomere length and elevated iron: the influence of phenotype and HFE genotype.

Mainous AG 3rd, Wright RU, Hulihan MM, Twal WO, McLaren CE, Diaz VA, McLaren GD, Argraves WS, Grant AM.

Am J Hematol. 2013 Jun;88(6):492-6. doi: 10.1002/ajh.23438. Epub 2013 May 13.


Optical imaging correlates with magnetic resonance imaging breast density and reveals composition changes during neoadjuvant chemotherapy.

O'Sullivan TD, Leproux A, Chen JH, Bahri S, Matlock A, Roblyer D, McLaren CE, Chen WP, Cerussi AE, Su MY, Tromberg BJ.

Breast Cancer Res. 2013 Feb 22;15(1):R14. doi: 10.1186/bcr3389.


Association between celiac disease and iron deficiency in Caucasians, but not non-Caucasians.

Murray JA, McLachlan S, Adams PC, Eckfeldt JH, Garner CP, Vulpe CD, Gordeuk VR, Brantner T, Leiendecker-Foster C, Killeen AA, Acton RT, Barcellos LF, Nickerson DA, Beckman KB, McLaren GD, McLaren CE.

Clin Gastroenterol Hepatol. 2013 Jul;11(7):808-14. doi: 10.1016/j.cgh.2013.02.009. Epub 2013 Feb 13.


Role of dietary polyamines in a phase III clinical trial of difluoromethylornithine (DFMO) and sulindac for prevention of sporadic colorectal adenomas.

Raj KP, Zell JA, Rock CL, McLaren CE, Zoumas-Morse C, Gerner EW, Meyskens FL.

Br J Cancer. 2013 Feb 19;108(3):512-8. doi: 10.1038/bjc.2013.15. Epub 2013 Jan 22.


Role of obesity in a randomized placebo-controlled trial of difluoromethylornithine (DFMO) + sulindac for the prevention of sporadic colorectal adenomas.

Zell JA, Lin BS, Madson N, McLaren CE, Gerner EW, Meyskens FL.

Cancer Causes Control. 2012 Oct;23(10):1739-44. doi: 10.1007/s10552-012-0051-6. Epub 2012 Aug 21.


Outcomes of high-dose-rate interstitial brachytherapy in the treatment of locally advanced cervical cancer: long-term results.

Pinn-Bingham M, Puthawala AA, Syed AM, Sharma A, Disaia P, Berman M, Tewari KS, Randall-Whitis L, Mahmood U, Ramsinghani N, Kuo J, Chen WP, McLaren CE.

Int J Radiat Oncol Biol Phys. 2013 Mar 1;85(3):714-20. doi: 10.1016/j.ijrobp.2012.05.033. Epub 2012 Jul 3.


Associations between single nucleotide polymorphisms in iron-related genes and iron status in multiethnic populations.

McLaren CE, McLachlan S, Garner CP, Vulpe CD, Gordeuk VR, Eckfeldt JH, Adams PC, Acton RT, Murray JA, Leiendecker-Foster C, Snively BM, Barcellos LF, Cook JD, McLaren GD.

PLoS One. 2012;7(6):e38339. doi: 10.1371/journal.pone.0038339. Epub 2012 Jun 22.


Probability of C282Y homozygosity decreases as liver transaminase activities increase in participants with hyperferritinemia in the hemochromatosis and iron overload screening study.

Adams PC, Speechley M, Barton JC, McLaren CE, McLaren GD, Eckfeldt JH.

Hepatology. 2012 Jun;55(6):1722-6. doi: 10.1002/hep.25538. Epub 2012 Apr 18.


A comparison of self-reported and record-linked blood donation history in an Australian cohort.

Bertalli NA, Allen KJ, McLaren CE, Turkovic L, Osborne NJ, Constantine CC, Delatycki MB, English DR, Giles GG, Hopper JL, Anderson GJ, Olynyk JK, Powell LW, Gurrin LC; HealthIron Study Investigators.

Transfusion. 2011 Oct;51(10):2189-98. doi: 10.1111/j.1537-2995.2011.03141.x. Epub 2011 Apr 19.


IRon Overload screeNing tool (IRON): development of a tool to guide screening in primary care.

Mainous AG 3rd, Diaz VA, Everett CJ, Knoll ME, Hulihan MM, Grant AM, McLaren CE, McLaren GD.

Am J Hematol. 2011 Sep;86(9):733-7. doi: 10.1002/ajh.22082. Epub 2011 Jul 28.


Genome-wide association study identifies genetic loci associated with iron deficiency.

McLaren CE, Garner CP, Constantine CC, McLachlan S, Vulpe CD, Snively BM, Gordeuk VR, Nickerson DA, Cook JD, Leiendecker-Foster C, Beckman KB, Eckfeldt JH, Barcellos LF, Murray JA, Adams PC, Acton RT, Killeen AA, McLaren GD.

PLoS One. 2011 Mar 31;6(3):e17390. doi: 10.1371/journal.pone.0017390.


Chemoprevention, risk reduction, therapeutic prevention, or preventive therapy?

Meyskens FL Jr, McLaren CE.

J Natl Cancer Inst. 2010 Dec 15;102(24):1815-7. doi: 10.1093/jnci/djq466. Epub 2010 Nov 29. No abstract available.


Melanoma: is hair the root of the problem?

Garcia AM, McLaren CE, Meyskens FL Jr.

Pigment Cell Melanoma Res. 2011 Feb;24(1):110-8. doi: 10.1111/j.1755-148X.2010.00782.x. Epub 2010 Oct 21. No abstract available.


Ornithine decarboxylase-1 polymorphism, chemoprevention with eflornithine and sulindac, and outcomes among colorectal adenoma patients.

Zell JA, McLaren CE, Chen WP, Thompson PA, Gerner EW, Meyskens FL.

J Natl Cancer Inst. 2010 Oct 6;102(19):1513-6. doi: 10.1093/jnci/djq325. Epub 2010 Aug 26.


EUS compared with endoscopy plus transabdominal US in the initial diagnostic evaluation of patients with upper abdominal pain.

Chang KJ, Erickson RA, Chak A, Lightdale C, Chen YK, Binmoeller KF, Albers GC, Chen WP, McLaren CE, Sivak MV, Lee JG, Isenberg GA, Wong RC.

Gastrointest Endosc. 2010 Nov;72(5):967-74. doi: 10.1016/j.gie.2010.04.007. Epub 2010 Jul 22.


Age- and race-dependence of the fibroglandular breast density analyzed on 3D MRI.

Nie K, Su MY, Chau MK, Chan S, Nguyen H, Tseng T, Huang Y, McLaren CE, Nalcioglu O, Chen JH.

Med Phys. 2010 Jun;37(6):2770-6.


HFE Cys282Tyr homozygotes with serum ferritin concentrations below 1000 microg/L are at low risk of hemochromatosis.

Allen KJ, Bertalli NA, Osborne NJ, Constantine CC, Delatycki MB, Nisselle AE, Nicoll AJ, Gertig DM, McLaren CE, Giles GG, Hopper JL, Anderson GJ, Olynyk JK, Powell LW, Gurrin LC; HealthIron Study Investigators.

Hepatology. 2010 Sep;52(3):925-33. doi: 10.1002/hep.23786.


Levels of rectal mucosal polyamines and prostaglandin E2 predict ability of DFMO and sulindac to prevent colorectal adenoma.

Thompson PA, Wertheim BC, Zell JA, Chen WP, McLaren CE, LaFleur BJ, Meyskens FL, Gerner EW.

Gastroenterology. 2010 Sep;139(3):797-805, 805.e1. doi: 10.1053/j.gastro.2010.06.005. Epub 2010 Jun 9.


Tumor necrosis factor-alpha promoter variants and iron phenotypes in 785 hemochromatosis and iron overload screening (HEIRS) study participants.

Acton RT, Barton JC, Leiendecker-Foster C, Zaun C, McLaren CE, Eckfeldt JH.

Blood Cells Mol Dis. 2010 Apr 15;44(4):252-6. doi: 10.1016/j.bcmd.2010.01.007. Epub 2010 Feb 23.

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