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Items: 1 to 50 of 138

1.

Charge site mass spectra: conformation-sensitive components of the electron capture dissociation spectrum of a protein.

Skinner OS, Breuker K, McLafferty FW.

J Am Soc Mass Spectrom. 2013 Jun;24(6):807-10. doi: 10.1007/s13361-013-0603-3. Epub 2013 Apr 3.

2.

Thiamin biosynthesis: still yielding fascinating biological chemistry.

Begley TP, Ealick SE, McLafferty FW.

Biochem Soc Trans. 2012 Jun 1;40(3):555-60. doi: 10.1042/BST20120084. Review.

3.

How ubiquitin unfolds after transfer into the gas phase.

Skinner OS, McLafferty FW, Breuker K.

J Am Soc Mass Spectrom. 2012 Jun;23(6):1011-4. doi: 10.1007/s13361-012-0370-6. Epub 2012 Apr 3.

4.

Femtosecond laser vaporization that preserves protein-folded structure: an unproven idea.

Breuker K, Skinner OS, McLafferty FW.

Proc Natl Acad Sci U S A. 2012 Jan 31;109(5):E206; author reply E207. doi: 10.1073/pnas.1115475109. Epub 2012 Jan 26. No abstract available.

5.

A century of progress in molecular mass spectrometry.

McLafferty FW.

Annu Rev Anal Chem (Palo Alto Calif). 2011;4:1-22. doi: 10.1146/annurev-anchem-061010-114018.

PMID:
21351881
6.

Numerous isomers of serine octamer ions characterized by infrared photodissociation spectroscopy.

Kong X, Lin C, Infusini G, Oh HB, Jiang H, Breuker K, Wu CC, Charkin OP, Chang HC, McLafferty FW.

Chemphyschem. 2009 Oct 19;10(15):2603-6. doi: 10.1002/cphc.200900564. No abstract available.

7.

IgE receptor-mediated alteration of membrane-cytoskeleton interactions revealed by mass spectrometric analysis of detergent-resistant membranes.

Han X, Smith NL, Sil D, Holowka DA, McLafferty FW, Baird BA.

Biochemistry. 2009 Jul 14;48(27):6540-50. doi: 10.1021/bi900181w.

8.

Stepwise evolution of protein native structure with electrospray into the gas phase, 10(-12) to 10(2) s.

Breuker K, McLafferty FW.

Proc Natl Acad Sci U S A. 2008 Nov 25;105(47):18145-52. doi: 10.1073/pnas.0807005105.

9.

Mass spectrometry across the sciences.

McLafferty FW.

Proc Natl Acad Sci U S A. 2008 Nov 25;105(47):18088-9. doi: 10.1073/pnas.0800784105. Epub 2008 Oct 15. No abstract available.

10.

Early structural evolution of native cytochrome c after solvent removal.

Steinberg MZ, Elber R, McLafferty FW, Gerber RB, Breuker K.

Chembiochem. 2008 Oct 13;9(15):2417-23. doi: 10.1002/cbic.200800167.

11.

Top-down identification and characterization of biomolecules by mass spectrometry.

Breuker K, Jin M, Han X, Jiang H, McLafferty FW.

J Am Soc Mass Spectrom. 2008 Aug;19(8):1045-53. doi: 10.1016/j.jasms.2008.05.013. Epub 2008 May 28. Review.

12.

Focus in honor of Roman Zubarev, recipient of the 2007 Biemann Medal.

Brodbelt JS, McLafferty FW, Kelleher NL.

J Am Soc Mass Spectrom. 2008 Jun;19(6):751-2. doi: 10.1016/j.jasms.2008.04.021. No abstract available.

13.

Detecting native folds in mixtures of proteins that contain disulfide bonds.

Narayan M, Welker E, Zhai H, Han X, Xu G, McLafferty FW, Scheraga HA.

Nat Biotechnol. 2008 Apr;26(4):427-9. doi: 10.1038/nbt1380. Epub 2008 Feb 17.

14.

Multi-step evolution of protein conformation on electrospray into the gas phase.

McLafferty FW, Castro S, Breuker K.

Eur J Mass Spectrom (Chichester). 2010;16(3):437-42. doi: 10.1255/ejms.1058.

PMID:
20530828
15.

Top-down MS, a powerful complement to the high capabilities of proteolysis proteomics.

McLafferty FW, Breuker K, Jin M, Han X, Infusini G, Jiang H, Kong X, Begley TP.

FEBS J. 2007 Dec;274(24):6256-68. Epub 2007 Nov 16. Review.

16.

Focus in honor of David E. Clemmer, recipient of the 2006 Biemann medal.

Bierbaum VM, McLafferty FW.

J Am Soc Mass Spectrom. 2007 Jul;18(7):1161-2. Epub 2007 May 13. No abstract available.

17.

Biosynthesis of the thioquinolobactin siderophore: an interesting variation on sulfur transfer.

Godert AM, Jin M, McLafferty FW, Begley TP.

J Bacteriol. 2007 Apr;189(7):2941-4. Epub 2007 Jan 5.

18.

Extending top-down mass spectrometry to proteins with masses greater than 200 kilodaltons.

Han X, Jin M, Breuker K, McLafferty FW.

Science. 2006 Oct 6;314(5796):109-12.

19.

Biosynthesis of thiamin thiazole: determination of the regiochemistry of the S/O acyl shift by using 1,4-dideoxy-D-xylulose-5-phosphate.

Chatterjee A, Han X, McLafferty FW, Begley TP.

Angew Chem Int Ed Engl. 2006 May 19;45(21):3507-10. No abstract available.

PMID:
16625663
20.

Stepwise deamidation of ribonuclease A at five sites determined by top down mass spectrometry.

Zabrouskov V, Han X, Welker E, Zhai H, Lin C, van Wijk KJ, Scheraga HA, McLafferty FW.

Biochemistry. 2006 Jan 24;45(3):987-92.

21.

Consecutive ion activation for top down mass spectrometry: improved protein sequencing by nozzle-skimmer dissociation.

Zhai H, Han X, Breuker K, McLafferty FW.

Anal Chem. 2005 Sep 15;77(18):5777-84.

PMID:
16159106
22.

Reconstitution of a new cysteine biosynthetic pathway in Mycobacterium tuberculosis.

Burns KE, Baumgart S, Dorrestein PC, Zhai H, McLafferty FW, Begley TP.

J Am Chem Soc. 2005 Aug 24;127(33):11602-3.

23.

The thermal unfolding of native cytochrome c in the transition from solution to gas phase probed by native electron capture dissociation.

Breuker K, McLafferty FW.

Angew Chem Int Ed Engl. 2005 Aug 5;44(31):4911-4. No abstract available.

PMID:
15999374
24.

Simultaneous kinetic characterization of multiple protein forms by top down mass spectrometry.

Zhai H, Dorrestein PC, Chatterjee A, Begley TP, McLafferty FW.

J Am Soc Mass Spectrom. 2005 Jul;16(7):1052-9.

25.

The mechanism of inactivation of 3-hydroxyanthranilate-3,4-dioxygenase by 4-chloro-3-hydroxyanthranilate.

Colabroy KL, Zhai H, Li T, Ge Y, Zhang Y, Liu A, Ealick SE, McLafferty FW, Begley TP.

Biochemistry. 2005 May 31;44(21):7623-31.

PMID:
15909977
26.

Infrared photodissociation spectroscopy of electrosprayed ions in a Fourier transform mass spectrometer.

Oh HB, Lin C, Hwang HY, Zhai H, Breuker K, Zabrouskov V, Carpenter BK, McLafferty FW.

J Am Chem Soc. 2005 Mar 23;127(11):4076-83.

PMID:
15771545
27.

Reconstitution and biochemical characterization of a new pyridoxal-5'-phosphate biosynthetic pathway.

Burns KE, Xiang Y, Kinsland CL, McLafferty FW, Begley TP.

J Am Chem Soc. 2005 Mar 23;127(11):3682-3.

PMID:
15771487
28.

Mechanistic studies on phosphopantothenoylcysteine decarboxylase: trapping of an enethiolate intermediate with a mechanism-based inactivating agent.

Strauss E, Zhai H, Brand LA, McLafferty FW, Begley TP.

Biochemistry. 2004 Dec 14;43(49):15520-33.

PMID:
15581364
29.
30.

Nonergodic and conformational control of the electron capture dissociation of protein cations.

Breuker K, Oh H, Lin C, Carpenter BK, McLafferty FW.

Proc Natl Acad Sci U S A. 2004 Sep 28;101(39):14011-6. Epub 2004 Sep 20.

31.

Thiamin biosynthesis in Bacillus subtilis: structure of the thiazole synthase/sulfur carrier protein complex.

Settembre EC, Dorrestein PC, Zhai H, Chatterjee A, McLafferty FW, Begley TP, Ealick SE.

Biochemistry. 2004 Sep 21;43(37):11647-57.

PMID:
15362849
32.

Simultaneous characterization of the reductive unfolding pathways of RNase B isoforms by top-down mass spectrometry.

Xu G, Zhai H, Narayan M, McLafferty FW, Scheraga HA.

Chem Biol. 2004 Apr;11(4):517-24.

33.

Dissimilarity in the reductive unfolding pathways of two ribonuclease homologues.

Narayan M, Xu G, Ripoll DR, Zhai H, Breuker K, Wanjalla C, Leung HJ, Navon A, Welker E, McLafferty FW, Scheraga HA.

J Mol Biol. 2004 May 7;338(4):795-809.

PMID:
15099746
34.

The biosynthesis of the thiazole phosphate moiety of thiamin (vitamin B1): the early steps catalyzed by thiazole synthase.

Dorrestein PC, Zhai H, Taylor SV, McLafferty FW, Begley TP.

J Am Chem Soc. 2004 Mar 17;126(10):3091-6.

PMID:
15012138
35.

Native electron capture dissociation for the structural characterization of noncovalent interactions in native cytochrome C.

Breuker K, McLafferty FW.

Angew Chem Int Ed Engl. 2003 Oct 20;42(40):4900-4. No abstract available.

PMID:
14579433
36.

Biosynthesis of the thiazole moiety of thiamin pyrophosphate (vitamin B1).

Park JH, Dorrestein PC, Zhai H, Kinsland C, McLafferty FW, Begley TP.

Biochemistry. 2003 Oct 28;42(42):12430-8.

PMID:
14567704
37.

A new approach for plant proteomics: characterization of chloroplast proteins of Arabidopsis thaliana by top-down mass spectrometry.

Zabrouskov V, Giacomelli L, van Wijk KJ, McLafferty FW.

Mol Cell Proteomics. 2003 Dec;2(12):1253-60. Epub 2003 Sep 22.

38.

Detection of four oxidation sites in viral prolyl-4-hydroxylase by top-down mass spectrometry.

Ge Y, Lawhorn BG, ElNaggar M, Sze SK, Begley TP, McLafferty FW.

Protein Sci. 2003 Oct;12(10):2320-6.

39.

Plasma electron capture dissociation for the characterization of large proteins by top down mass spectrometry.

Sze SK, Ge Y, Oh H, McLafferty FW.

Anal Chem. 2003 Apr 1;75(7):1599-603.

PMID:
12705591
40.

Top down characterization of secreted proteins from Mycobacterium tuberculosis by electron capture dissociation mass spectrometry.

Ge Y, El-Naggar M, Sze SK, Oh HB, Begley TP, McLafferty FW, Boshoff H, Barry CE 3rd.

J Am Soc Mass Spectrom. 2003 Mar;14(3):253-61.

41.

Secondary and tertiary structures of gaseous protein ions characterized by electron capture dissociation mass spectrometry and photofragment spectroscopy.

Oh H, Breuker K, Sze SK, Ge Y, Carpenter BK, McLafferty FW.

Proc Natl Acad Sci U S A. 2002 Dec 10;99(25):15863-8. Epub 2002 Nov 20.

42.

Sequencing of specific copolymer oligomers by electron-capture-dissociation mass spectrometry.

Cerda BA, Horn DM, Breuker K, McLafferty FW.

J Am Chem Soc. 2002 Aug 7;124(31):9287-91.

PMID:
12149036
43.

Detailed unfolding and folding of gaseous ubiquitin ions characterized by electron capture dissociation.

Breuker K, Oh H, Horn DM, Cerda BA, McLafferty FW.

J Am Chem Soc. 2002 Jun 5;124(22):6407-20.

PMID:
12033872
44.

Top-down mass spectrometry of a 29-kDa protein for characterization of any posttranslational modification to within one residue.

Sze SK, Ge Y, Oh H, McLafferty FW.

Proc Natl Acad Sci U S A. 2002 Feb 19;99(4):1774-9. Epub 2002 Feb 12.

45.

Top down characterization of larger proteins (45 kDa) by electron capture dissociation mass spectrometry.

Ge Y, Lawhorn BG, ElNaggar M, Strauss E, Park JH, Begley TP, McLafferty FW.

J Am Chem Soc. 2002 Jan 30;124(4):672-8.

PMID:
11804498
46.

Kinetic intermediates in the folding of gaseous protein ions characterized by electron capture dissociation mass spectrometry.

Horn DM, Breuker K, Frank AJ, McLafferty FW.

J Am Chem Soc. 2001 Oct 10;123(40):9792-9.

PMID:
11583540
47.
48.

Electrospray ionization mass spectrometry analysis of changes in phospholipids in RBL-2H3 mastocytoma cells during degranulation.

Ivanova PT, Cerda BA, Horn DM, Cohen JS, McLafferty FW, Brown HA.

Proc Natl Acad Sci U S A. 2001 Jun 19;98(13):7152-7.

49.
50.

Electron capture dissociation of gaseous multiply charged ions by Fourier-transform ion cyclotron resonance.

McLafferty FW, Horn DM, Breuker K, Ge Y, Lewis MA, Cerda B, Zubarev RA, Carpenter BK.

J Am Soc Mass Spectrom. 2001 Mar;12(3):245-9. Review.

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