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Items: 1 to 50 of 159

1.

RiboTag: Ribosomal Tagging Strategy to Analyze Cell-Type-Specific mRNA Expression In Vivo.

Sanz E, Bean JC, Carey DP, Quintana A, McKnight GS.

Curr Protoc Neurosci. 2019 Jun;88(1):e77. doi: 10.1002/cpns.77.

PMID:
31216392
2.

AKAP1 Protects from Cerebral Ischemic Stroke by Inhibiting Drp1-Dependent Mitochondrial Fission.

Flippo KH, Gnanasekaran A, Perkins GA, Ajmal A, Merrill RA, Dickey AS, Taylor SS, McKnight GS, Chauhan AK, Usachev YM, Strack S.

J Neurosci. 2018 Sep 19;38(38):8233-8242. doi: 10.1523/JNEUROSCI.0649-18.2018. Epub 2018 Aug 9.

3.

Targeted deletion of AKAP7 in dentate granule cells impairs spatial discrimination.

Jones BW, Deem J, Younts TJ, Weisenhaus M, Sanford CA, Slack MC, Chin J, Nachmanson D, McKennon A, Castillo PE, McKnight GS.

Elife. 2016 Dec 2;5. pii: e20695. doi: 10.7554/eLife.20695.

4.

Loss of AKAP150 promotes pathological remodelling and heart failure propensity by disrupting calcium cycling and contractile reserve.

Li L, Li J, Drum BM, Chen Y, Yin H, Guo X, Luckey SW, Gilbert ML, McKnight GS, Scott JD, Santana LF, Liu Q.

Cardiovasc Res. 2017 Feb;113(2):147-159. doi: 10.1093/cvr/cvw221. Epub 2016 Nov 17.

5.

Enhanced cAMP-stimulated protein kinase A activity in human fibrolamellar hepatocellular carcinoma.

Riggle KM, Riehle KJ, Kenerson HL, Turnham R, Homma MK, Kazami M, Samelson B, Bauer R, McKnight GS, Scott JD, Yeung RS.

Pediatr Res. 2016 Jul;80(1):110-8. doi: 10.1038/pr.2016.36. Epub 2016 Mar 8.

6.

Hypothalamic PKA regulates leptin sensitivity and adiposity.

Yang L, McKnight GS.

Nat Commun. 2015 Sep 18;6:8237. doi: 10.1038/ncomms9237.

7.

Fertility-regulating Kiss1 neurons arise from hypothalamic POMC-expressing progenitors.

Sanz E, Quintana A, Deem JD, Steiner RA, Palmiter RD, McKnight GS.

J Neurosci. 2015 Apr 8;35(14):5549-56. doi: 10.1523/JNEUROSCI.3614-14.2015.

8.

Expression of a dominant negative PKA mutation in the kidney elicits a diabetes insipidus phenotype.

Gilbert ML, Yang L, Su T, McKnight GS.

Am J Physiol Renal Physiol. 2015 Mar 15;308(6):F627-38. doi: 10.1152/ajprenal.00222.2014. Epub 2015 Jan 13.

9.

Mutations affecting the SAND domain of DEAF1 cause intellectual disability with severe speech impairment and behavioral problems.

Vulto-van Silfhout AT, Rajamanickam S, Jensik PJ, Vergult S, de Rocker N, Newhall KJ, Raghavan R, Reardon SN, Jarrett K, McIntyre T, Bulinski J, Ownby SL, Huggenvik JI, McKnight GS, Rose GM, Cai X, Willaert A, Zweier C, Endele S, de Ligt J, van Bon BW, Lugtenberg D, de Vries PF, Veltman JA, van Bokhoven H, Brunner HG, Rauch A, de Brouwer AP, Carvill GL, Hoischen A, Mefford HC, Eichler EE, Vissers LE, Menten B, Collard MW, de Vries BB.

Am J Hum Genet. 2014 May 1;94(5):649-61. doi: 10.1016/j.ajhg.2014.03.013. Epub 2014 Apr 10.

10.
11.

NR2B subunit of the NMDA glutamate receptor regulates appetite in the parabrachial nucleus.

Wu Q, Zheng R, Srisai D, McKnight GS, Palmiter RD.

Proc Natl Acad Sci U S A. 2013 Sep 3;110(36):14765-70. doi: 10.1073/pnas.1314137110. Epub 2013 Aug 20.

12.

RiboTag analysis of actively translated mRNAs in Sertoli and Leydig cells in vivo.

Sanz E, Evanoff R, Quintana A, Evans E, Miller JA, Ko C, Amieux PS, Griswold MD, McKnight GS.

PLoS One. 2013 Jun 11;8(6):e66179. doi: 10.1371/journal.pone.0066179. Print 2013.

13.

Deficiency of the RIIβ subunit of PKA affects locomotor activity and energy homeostasis in distinct neuronal populations.

Zheng R, Yang L, Sikorski MA, Enns LC, Czyzyk TA, Ladiges WC, McKnight GS.

Proc Natl Acad Sci U S A. 2013 Apr 23;110(17):E1631-40. doi: 10.1073/pnas.1219542110. Epub 2013 Apr 8.

14.

Lack of GPR88 enhances medium spiny neuron activity and alters motor- and cue-dependent behaviors.

Quintana A, Sanz E, Wang W, Storey GP, Güler AD, Wanat MJ, Roller BA, La Torre A, Amieux PS, McKnight GS, Bamford NS, Palmiter RD.

Nat Neurosci. 2012 Nov;15(11):1547-55. doi: 10.1038/nn.3239. Epub 2012 Oct 14.

15.

Cardiomyocytes from AKAP7 knockout mice respond normally to adrenergic stimulation.

Jones BW, Brunet S, Gilbert ML, Nichols CB, Su T, Westenbroek RE, Scott JD, Catterall WA, McKnight GS.

Proc Natl Acad Sci U S A. 2012 Oct 16;109(42):17099-104. doi: 10.1073/pnas.1215219109. Epub 2012 Oct 3.

16.

Molecular properties of Kiss1 neurons in the arcuate nucleus of the mouse.

Gottsch ML, Popa SM, Lawhorn JK, Qiu J, Tonsfeldt KJ, Bosch MA, Kelly MJ, Rønnekleiv OK, Sanz E, McKnight GS, Clifton DK, Palmiter RD, Steiner RA.

Endocrinology. 2011 Nov;152(11):4298-309. doi: 10.1210/en.2011-1521. Epub 2011 Sep 20.

17.

Cell-type specific expression of a dominant negative PKA mutation in mice.

Willis BS, Niswender CM, Su T, Amieux PS, McKnight GS.

PLoS One. 2011 Apr 12;6(4):e18772. doi: 10.1371/journal.pone.0018772.

18.

Platelet microRNA-mRNA coexpression profiles correlate with platelet reactivity.

Nagalla S, Shaw C, Kong X, Kondkar AA, Edelstein LC, Ma L, Chen J, McKnight GS, López JA, Yang L, Jin Y, Bray MS, Leal SM, Dong JF, Bray PF.

Blood. 2011 May 12;117(19):5189-97. doi: 10.1182/blood-2010-09-299719. Epub 2011 Mar 17.

19.

Sympathetic stimulation of adult cardiomyocytes requires association of AKAP5 with a subpopulation of L-type calcium channels.

Nichols CB, Rossow CF, Navedo MF, Westenbroek RE, Catterall WA, Santana LF, McKnight GS.

Circ Res. 2010 Sep 17;107(6):747-56. doi: 10.1161/CIRCRESAHA.109.216127. Epub 2010 Jul 29.

20.

Mutations in AKAP5 disrupt dendritic signaling complexes and lead to electrophysiological and behavioral phenotypes in mice.

Weisenhaus M, Allen ML, Yang L, Lu Y, Nichols CB, Su T, Hell JW, McKnight GS.

PLoS One. 2010 Apr 23;5(4):e10325. doi: 10.1371/journal.pone.0010325.

21.

The contribution of AKAP5 in amylase secretion from mouse parotid acini.

Wu CY, DiJulio DH, Jacobson KL, McKnight GS, Watson EL.

Am J Physiol Cell Physiol. 2010 May;298(5):C1151-8. doi: 10.1152/ajpcell.00382.2009. Epub 2010 Feb 17.

22.

Cyclic nucleotides converge on brown adipose tissue differentiation.

Amieux PS, McKnight GS.

Sci Signal. 2010 Jan 12;3(104):pe2. doi: 10.1126/scisignal.3104pe2.

PMID:
20068229
23.

Attenuation of age-related metabolic dysfunction in mice with a targeted disruption of the Cbeta subunit of protein kinase A.

Enns LC, Morton JF, Mangalindan RS, McKnight GS, Schwartz MW, Kaeberlein MR, Kennedy BK, Rabinovitch PS, Ladiges WC.

J Gerontol A Biol Sci Med Sci. 2009 Dec;64(12):1221-31. doi: 10.1093/gerona/glp133. Epub 2009 Sep 23.

24.

Cell-type-specific isolation of ribosome-associated mRNA from complex tissues.

Sanz E, Yang L, Su T, Morris DR, McKnight GS, Amieux PS.

Proc Natl Acad Sci U S A. 2009 Aug 18;106(33):13939-44. doi: 10.1073/pnas.0907143106. Epub 2009 Aug 4.

25.

Disruption of protein kinase A in mice enhances healthy aging.

Enns LC, Morton JF, Treuting PR, Emond MJ, Wolf NS, Dai DF, McKnight GS, Rabinovitch PS, Ladiges WC.

PLoS One. 2009 Jun 18;4(6):e5963. doi: 10.1371/journal.pone.0005963. Erratum in: PLoS One. 2010;5(2) doi: 10.1371/annotation/c7cad2dc-1eca-487e-89ae-151a22d8a0b4. Dai, Dao-Fu [added].

26.

Loss of the Synaptic Vesicle Protein SV2B results in reduced neurotransmission and altered synaptic vesicle protein expression in the retina.

Morgans CW, Kensel-Hammes P, Hurley JB, Burton K, Idzerda R, McKnight GS, Bajjalieh SM.

PLoS One. 2009;4(4):e5230. doi: 10.1371/journal.pone.0005230. Epub 2009 Apr 17.

27.

Specific recruitment of protein kinase A to the immunoglobulin locus regulates class-switch recombination.

Vuong BQ, Lee M, Kabir S, Irimia C, Macchiarulo S, McKnight GS, Chaudhuri J.

Nat Immunol. 2009 Apr;10(4):420-6. doi: 10.1038/ni.1708. Epub 2009 Feb 22.

28.

Tissue-specific PKA inhibition using a chemical genetic approach and its application to studies on sperm capacitation.

Morgan DJ, Weisenhaus M, Shum S, Su T, Zheng R, Zhang C, Shokat KM, Hille B, Babcock DF, McKnight GS.

Proc Natl Acad Sci U S A. 2008 Dec 30;105(52):20740-5. doi: 10.1073/pnas.0810971105. Epub 2008 Dec 12.

29.

AKAP150-anchored PKA activity is important for LTD during its induction phase.

Lu Y, Zhang M, Lim IA, Hall DD, Allen M, Medvedeva Y, McKnight GS, Usachev YM, Hell JW.

J Physiol. 2008 Sep 1;586(17):4155-64. doi: 10.1113/jphysiol.2008.151662. Epub 2008 Jul 10.

30.

Protein kinase A anchoring via AKAP150 is essential for TRPV1 modulation by forskolin and prostaglandin E2 in mouse sensory neurons.

Schnizler K, Shutov LP, Van Kanegan MJ, Merrill MA, Nichols B, McKnight GS, Strack S, Hell JW, Usachev YM.

J Neurosci. 2008 May 7;28(19):4904-17. doi: 10.1523/JNEUROSCI.0233-08.2008.

31.

Melanocyte-lineage expression of Cre recombinase using Mitf regulatory elements.

Alizadeh A, Fitch KR, Niswender CM, McKnight GS, Barsh GS.

Pigment Cell Melanoma Res. 2008 Feb;21(1):63-9. doi: 10.1111/j.1755-148X.2007.00425.x.

PMID:
18353144
32.

AKAP150 is required for stuttering persistent Ca2+ sparklets and angiotensin II-induced hypertension.

Navedo MF, Nieves-Cintrón M, Amberg GC, Yuan C, Votaw VS, Lederer WJ, McKnight GS, Santana LF.

Circ Res. 2008 Feb 1;102(2):e1-e11. doi: 10.1161/CIRCRESAHA.107.167809. Epub 2008 Jan 3.

PMID:
18174462
33.

Disruption of the RIIbeta subunit of PKA reverses the obesity syndrome of Agouti lethal yellow mice.

Czyzyk TA, Sikorski MA, Yang L, McKnight GS.

Proc Natl Acad Sci U S A. 2008 Jan 8;105(1):276-81. doi: 10.1073/pnas.0710607105. Epub 2008 Jan 2.

34.

Age-dependent requirement of AKAP150-anchored PKA and GluR2-lacking AMPA receptors in LTP.

Lu Y, Allen M, Halt AR, Weisenhaus M, Dallapiazza RF, Hall DD, Usachev YM, McKnight GS, Hell JW.

EMBO J. 2007 Nov 28;26(23):4879-90. Epub 2007 Nov 1.

35.

Alpha4 integrins are type I cAMP-dependent protein kinase-anchoring proteins.

Lim CJ, Han J, Yousefi N, Ma Y, Amieux PS, McKnight GS, Taylor SS, Ginsberg MH.

Nat Cell Biol. 2007 Apr;9(4):415-21. Epub 2007 Mar 18.

PMID:
17369818
36.

PKA, germ cells, and fertility.

Burton KA, McKnight GS.

Physiology (Bethesda). 2007 Feb;22:40-6. Review.

37.

Critical role of cAMP-dependent protein kinase anchoring to the L-type calcium channel Cav1.2 via A-kinase anchor protein 150 in neurons.

Hall DD, Davare MA, Shi M, Allen ML, Weisenhaus M, McKnight GS, Hell JW.

Biochemistry. 2007 Feb 13;46(6):1635-46. Epub 2007 Jan 20.

PMID:
17279627
38.

Reduced sodium current in GABAergic interneurons in a mouse model of severe myoclonic epilepsy in infancy.

Yu FH, Mantegazza M, Westenbroek RE, Robbins CA, Kalume F, Burton KA, Spain WJ, McKnight GS, Scheuer T, Catterall WA.

Nat Neurosci. 2006 Sep;9(9):1142-9. Epub 2006 Aug 20. Erratum in: Nat Neurosci. 2007 Jan;10(1):134.

PMID:
16921370
39.

Psychosis pathways converge via D2high dopamine receptors.

Seeman P, Schwarz J, Chen JF, Szechtman H, Perreault M, McKnight GS, Roder JC, Quirion R, Boksa P, Srivastava LK, Yanai K, Weinshenker D, Sumiyoshi T.

Synapse. 2006 Sep 15;60(4):319-46. Review.

PMID:
16786561
40.

Haploinsufficiency at the protein kinase A RI alpha gene locus leads to fertility defects in male mice and men.

Burton KA, McDermott DA, Wilkes D, Poulsen MN, Nolan MA, Goldstein M, Basson CT, McKnight GS.

Mol Endocrinol. 2006 Oct;20(10):2504-13. Epub 2006 May 25.

41.

Involvement of protein kinase A in patterning of the mouse somatosensory cortex.

Watson RF, Abdel-Majid RM, Barnett MW, Willis BS, Katsnelson A, Gillingwater TH, McKnight GS, Kind PC, Neumann PE.

J Neurosci. 2006 May 17;26(20):5393-401.

42.

Dynamic anchoring of PKA is essential during oocyte maturation.

Newhall KJ, Criniti AR, Cheah CS, Smith KC, Kafer KE, Burkart AD, McKnight GS.

Curr Biol. 2006 Feb 7;16(3):321-7.

43.

Inhibition of protein kinase A in murine enteric neurons causes lethal intestinal pseudo-obstruction.

Howe DG, Clarke CM, Yan H, Willis BS, Schneider DA, McKnight GS, Kapur RP.

J Neurobiol. 2006 Feb 15;66(3):256-72.

44.

Signaling pathways for modulation of mouse sperm motility by adenosine and catecholamine agonists.

Schuh SM, Carlson AE, McKnight GS, Conti M, Hille B, Babcock DF.

Biol Reprod. 2006 Mar;74(3):492-500. Epub 2005 Nov 16.

PMID:
16291925
45.

Cre recombinase-dependent expression of a constitutively active mutant allele of the catalytic subunit of protein kinase A.

Niswender CM, Willis BS, Wallen A, Sweet IR, Jetton TL, Thompson BR, Wu C, Lange AJ, McKnight GS.

Genesis. 2005 Nov;43(3):109-19.

PMID:
16155866
46.

The role of protein kinase A anchoring via the RII alpha regulatory subunit in the murine immune system.

Schillace RV, Andrews SF, Galligan SG, Burton KA, Starks HJ, Bouwer HG, McKnight GS, Davey MP, Carr DW.

J Immunol. 2005 Jun 1;174(11):6847-53.

47.

Deletion of the RIIbeta-subunit of protein kinase A decreases body weight and increases energy expenditure in the obese, leptin-deficient ob/ob mouse.

Newhall KJ, Cummings DE, Nolan MA, McKnight GS.

Mol Endocrinol. 2005 Apr;19(4):982-91. Epub 2004 Dec 23.

PMID:
15618289
48.

Requirement for the RIIbeta isoform of PKA, but not calcium-stimulated adenylyl cyclase, in visual cortical plasticity.

Fischer QS, Beaver CJ, Yang Y, Rao Y, Jakobsdottir KB, Storm DR, McKnight GS, Daw NW.

J Neurosci. 2004 Oct 13;24(41):9049-58.

49.

Comparative PRKAR1A genotype-phenotype analyses in humans with Carney complex and prkar1a haploinsufficient mice.

Veugelers M, Wilkes D, Burton K, McDermott DA, Song Y, Goldstein MM, La Perle K, Vaughan CJ, O'Hagan A, Bennett KR, Meyer BJ, Legius E, Karttunen M, Norio R, Kaariainen H, Lavyne M, Neau JP, Richter G, Kirali K, Farnsworth A, Stapleton K, Morelli P, Takanashi Y, Bamforth JS, Eitelberger F, Noszian I, Manfroi W, Powers J, Mochizuki Y, Imai T, Ko GT, Driscoll DA, Goldmuntz E, Edelberg JM, Collins A, Eccles D, Irvine AD, McKnight GS, Basson CT.

Proc Natl Acad Sci U S A. 2004 Sep 28;101(39):14222-7. Epub 2004 Sep 15.

50.

Sperm-specific protein kinase A catalytic subunit Calpha2 orchestrates cAMP signaling for male fertility.

Nolan MA, Babcock DF, Wennemuth G, Brown W, Burton KA, McKnight GS.

Proc Natl Acad Sci U S A. 2004 Sep 14;101(37):13483-8. Epub 2004 Aug 31.

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