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Items: 1 to 50 of 159

1.

Communication Needs for Individuals With Rare Diseases Within and Around the Healthcare System of Northern Ireland.

Crowe AL, McKnight AJ, McAneney H.

Front Public Health. 2019 Aug 21;7:236. doi: 10.3389/fpubh.2019.00236. eCollection 2019.

2.

Differential methylation as a diagnostic biomarker of rare renal diseases: a systematic review.

Kerr K, McAneney H, Flanagan C, Maxwell AP, McKnight AJ.

BMC Nephrol. 2019 Aug 16;20(1):320. doi: 10.1186/s12882-019-1517-5.

3.

Genetic Susceptibility to Chronic Kidney Disease - Some More Pieces for the Heritability Puzzle.

Cañadas-Garre M, Anderson K, Cappa R, Skelly R, Smyth LJ, McKnight AJ, Maxwell AP.

Front Genet. 2019 May 31;10:453. doi: 10.3389/fgene.2019.00453. eCollection 2019. Review.

4.

Genomic Mismatch at LIMS1 Locus and Kidney Allograft Rejection.

Steers NJ, Li Y, Drace Z, D'Addario JA, Fischman C, Liu L, Xu K, Na YJ, Neugut YD, Zhang JY, Sterken R, Balderes O, Bradbury D, Ozturk N, Ozay F, Goswami S, Mehl K, Wold J, Jelloul FZ, Rohanizadegan M, Gillies CE, Vasilescu EM, Vlad G, Ko YA, Mohan S, Radhakrishnan J, Cohen DJ, Ratner LE, Scolari F, Susztak K, Sampson MG, Deaglio S, Caliskan Y, Barasch J, Courtney AE, Maxwell AP, McKnight AJ, Ionita-Laza I, Bakker SJL, Snieder H, de Borst MH, D'Agati V, Amoroso A, Gharavi AG, Kiryluk K.

N Engl J Med. 2019 May 16;380(20):1918-1928. doi: 10.1056/NEJMoa1803731.

PMID:
31091373
5.

Protocol for a scoping review of multi-omic analysis for rare diseases.

Kerr K, McAneney H, McKnight AJ.

BMJ Open. 2019 May 5;9(5):e026278. doi: 10.1136/bmjopen-2018-026278.

6.

Genetic associations between genes in the renin-angiotensin-aldosterone system and renal disease: a systematic review and meta-analysis.

Smyth LJ, Cañadas-Garre M, Cappa RC, Maxwell AP, McKnight AJ.

BMJ Open. 2019 May 1;9(4):e026777. doi: 10.1136/bmjopen-2018-026777.

7.

Communication strategies for rare cancers: a systematic review protocol.

Bell C, Kerr K, Moore K, McShane C, Anderson L, McKnight AJ, McAneney H.

Syst Rev. 2019 Apr 23;8(1):102. doi: 10.1186/s13643-019-1017-5.

8.

Socioeconomic position, lifestyle habits and biomarkers of epigenetic aging: a multi-cohort analysis.

Fiorito G, McCrory C, Robinson O, Carmeli C, Rosales CO, Zhang Y, Colicino E, Dugué PA, Artaud F, McKay GJ, Jeong A, Mishra PP, Nøst TH, Krogh V, Panico S, Sacerdote C, Tumino R, Palli D, Matullo G, Guarrera S, Gandini M, Bochud M, Dermitzakis E, Muka T, Schwartz J, Vokonas PS, Just A, Hodge AM, Giles GG, Southey MC, Hurme MA, Young I, McKnight AJ, Kunze S, Waldenberger M, Peters A, Schwettmann L, Lund E, Baccarelli A, Milne RL, Kenny RA, Elbaz A, Brenner H, Kee F, Voortman T, Probst-Hensch N, Lehtimäki T, Elliot P, Stringhini S, Vineis P, Polidoro S; BIOS Consortium; Lifepath consortium.

Aging (Albany NY). 2019 Apr 14;11(7):2045-2070. doi: 10.18632/aging.101900.

9.

Differential methylation in rare ophthalmic disorders: a systematic review protocol.

Kerr K, McAneney H, McKnight AJ.

Syst Rev. 2019 Apr 10;8(1):93. doi: 10.1186/s13643-019-0999-3.

10.

The impact of donor and recipient common clinical and genetic variation on estimated glomerular filtration rate in a European renal transplant population.

Stapleton CP, Heinzel A, Guan W, van der Most PJ, van Setten J, Lord GM, Keating BJ, Israni AK, de Borst MH, Bakker SJL, Snieder H, Weale ME, Delaney F, Hernandez-Fuentes MP, Reindl-Schwaighofer R, Oberbauer R, Jacobson PA, Mark PB, Chapman FA, Phelan PJ, Kennedy C, Sexton D, Murray S, Jardine A, Traynor JP, McKnight AJ, Maxwell AP, Smyth LJ, Oetting WS, Matas AJ, Mannon RB, Schladt DP, Iklé DN, Cavalleri GL, Conlon PJ; UK Ireland Renal Transplant Consortium; DeKAF Genomics and GEN03 Studies; International Genetics and Translational Research in Transplantation Network.

Am J Transplant. 2019 Aug;19(8):2262-2273. doi: 10.1111/ajt.15326. Epub 2019 Mar 28.

PMID:
30920136
11.

Validation of differentially methylated microRNAs identified from an epigenome-wide association study; Sanger and next generation sequencing approaches.

Smyth LJ, Maxwell AP, Benson KA, Kilner J, McKay GJ, McKnight AJ.

BMC Res Notes. 2018 Oct 29;11(1):767. doi: 10.1186/s13104-018-3872-x.

12.

Genomic approaches in the search for molecular biomarkers in chronic kidney disease.

Cañadas-Garre M, Anderson K, McGoldrick J, Maxwell AP, McKnight AJ.

J Transl Med. 2018 Oct 25;16(1):292. doi: 10.1186/s12967-018-1664-7. Review.

13.

Proteomic and metabolomic approaches in the search for biomarkers in chronic kidney disease.

Cañadas-Garre M, Anderson K, McGoldrick J, Maxwell AP, McKnight AJ.

J Proteomics. 2019 Feb 20;193:93-122. doi: 10.1016/j.jprot.2018.09.020. Epub 2018 Oct 5.

PMID:
30292816
14.

Information on Genetic Variants Does Not Increase Identification of Individuals at Risk of Esophageal Adenocarcinoma Compared to Clinical Risk Factors.

Kunzmann AT, Cañadas Garre M, Thrift AP, McMenamin ÚC, Johnston BT, Cardwell CR, Anderson LA, Spence AD, Lagergren J, Xie SH, Smyth LJ, McKnight AJ, Coleman HG.

Gastroenterology. 2019 Jan;156(1):43-45. doi: 10.1053/j.gastro.2018.09.038. Epub 2018 Sep 19.

PMID:
30243622
15.

Polygenic risk score as a determinant of risk of non-melanoma skin cancer in a European-descent renal transplant cohort.

Stapleton CP, Birdwell KA, McKnight AJ, Maxwell AP, Mark PB, Sanders ML, Chapman FA, van Setten J, Phelan PJ, Kennedy C, Jardine A, Traynor JP, Keating B, Conlon PJ, Cavalleri GL.

Am J Transplant. 2019 Mar;19(3):801-810. doi: 10.1111/ajt.15057. Epub 2018 Sep 5.

PMID:
30085400
16.

A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes.

van Zuydam NR, Ahlqvist E, Sandholm N, Deshmukh H, Rayner NW, Abdalla M, Ladenvall C, Ziemek D, Fauman E, Robertson NR, McKeigue PM, Valo E, Forsblom C, Harjutsalo V; Finnish Diabetic Nephropathy Study (FinnDiane), Perna A, Rurali E, Marcovecchio ML, Igo RP Jr, Salem RM, Perico N, Lajer M, Käräjämäki A, Imamura M, Kubo M, Takahashi A, Sim X, Liu J, van Dam RM, Jiang G, Tam CHT, Luk AOY, Lee HM, Lim CKP, Szeto CC, So WY, Chan JCN; Hong Kong Diabetes Registry Theme-based Research Scheme Project Group, Ang SF, Dorajoo R, Wang L, Clara TSH, McKnight AJ, Duffy S; Warren 3 and Genetics of Kidneys in Diabetes (GoKinD) Study Group, Pezzolesi MG; GENIE (GEnetics of Nephropathy an International Effort) Consortium, Marre M, Gyorgy B, Hadjadj S, Hiraki LT; Diabetes Control and Complications Trial (DCCT)/Epidemiology of Diabetes Interventions and Complications (EDIC) Research Group, Ahluwalia TS, Almgren P, Schulz CA, Orho-Melander M, Linneberg A, Christensen C, Witte DR, Grarup N, Brandslund I, Melander O, Paterson AD, Tregouet D, Maxwell AP, Lim SC, Ma RCW, Tai ES, Maeda S, Lyssenko V, Tuomi T, Krolewski AS, Rich SS, Hirschhorn JN, Florez JC, Dunger D, Pedersen O, Hansen T, Rossing P, Remuzzi G; SUrrogate markers for Micro- and Macrovascular hard endpoints for Innovative diabetes Tools (SUMMIT) Consortium, Brosnan MJ, Palmer CNA, Groop PH, Colhoun HM, Groop LC, McCarthy MI.

Diabetes. 2018 Jul;67(7):1414-1427. doi: 10.2337/db17-0914. Epub 2018 Apr 27.

17.

Novel risk genes identified in a genome-wide association study for coronary artery disease in patients with type 1 diabetes.

Charmet R, Duffy S, Keshavarzi S, Gyorgy B, Marre M, Rossing P, McKnight AJ, Maxwell AP, Ahluwalia TVS, Paterson AD, Trégouët DA, Hadjadj S.

Cardiovasc Diabetol. 2018 Apr 25;17(1):61. doi: 10.1186/s12933-018-0705-0.

18.

Design and implementation of a custom next generation sequencing panel for selected vitamin D associated genes.

Benson KA, Chand S, Maxwell AP, Smyth LJ, Kilner J, Borrows R, McKnight AJ.

BMC Res Notes. 2017 Jul 28;10(1):348. doi: 10.1186/s13104-017-2664-z.

19.

Development of next generation sequencing panel for UMOD and association with kidney disease.

Bailie C, Kilner J, Maxwell AP, McKnight AJ.

PLoS One. 2017 Jun 13;12(6):e0178321. doi: 10.1371/journal.pone.0178321. eCollection 2017.

20.

Candidate gene analysis of asthma in a population of Arab descent: a case-control study in Jordan.

Almomani BA, Al-Eitan LN, Samrah SM, Al-Quasmi MN, McKnight AJ.

Per Med. 2017 Jan;14(1):51-61. doi: 10.2217/pme-2016-0059. Epub 2016 Nov 30.

PMID:
29749828
21.

The Genetic Landscape of Renal Complications in Type 1 Diabetes.

Sandholm N, Van Zuydam N, Ahlqvist E, Juliusdottir T, Deshmukh HA, Rayner NW, Di Camillo B, Forsblom C, Fadista J, Ziemek D, Salem RM, Hiraki LT, Pezzolesi M, Trégouët D, Dahlström E, Valo E, Oskolkov N, Ladenvall C, Marcovecchio ML, Cooper J, Sambo F, Malovini A, Manfrini M, McKnight AJ, Lajer M, Harjutsalo V, Gordin D, Parkkonen M; The FinnDiane Study Group, Tuomilehto J, Lyssenko V, McKeigue PM, Rich SS, Brosnan MJ, Fauman E, Bellazzi R, Rossing P, Hadjadj S, Krolewski A, Paterson AD; The DCCT/EDIC Study Group, Florez JC, Hirschhorn JN, Maxwell AP; GENIE Consortium, Dunger D, Cobelli C, Colhoun HM, Groop L, McCarthy MI, Groop PH; SUMMIT Consortium.

J Am Soc Nephrol. 2017 Feb;28(2):557-574. doi: 10.1681/ASN.2016020231. Epub 2016 Sep 19.

22.

A Validation Study of Vascular Cognitive Impairment Genetics Meta-Analysis Findings in an Independent Collaborative Cohort.

Skrobot OA, McKnight AJ, Passmore PA, Seripa D, Mecocci P, Panza F, Kalaria R, Wilcock G, Munafò M, Erkinjuntti T, Karhunen P, Pessi T, Martiskainen M, Love S; Genetic and Environmental Risk for Alzheimer’s disease Consortium (GERAD1), Kehoe PG.

J Alzheimers Dis. 2016 Jun 15;53(3):981-9. doi: 10.3233/JAD-150862.

PMID:
27314523
23.

Analysis of single nucleotide polymorphisms implicate mTOR signalling in the development of new-onset diabetes after transplantation.

Chand S, McKnight AJ, Shabir S, Chan W, McCaughan JA, Maxwell AP, Harper L, Borrows R.

BBA Clin. 2016 Jan 8;5:41-5. doi: 10.1016/j.bbacli.2015.12.004. eCollection 2016 Jun.

24.

A HuGE Review and Meta-Analyses of Genetic Associations in New Onset Diabetes after Kidney Transplantation.

Benson KA, Maxwell AP, McKnight AJ.

PLoS One. 2016 Jan 20;11(1):e0147323. doi: 10.1371/journal.pone.0147323. eCollection 2016. Review.

25.

Genetic Evidence for a Causal Role of Obesity in Diabetic Kidney Disease.

Todd JN, Dahlström EH, Salem RM, Sandholm N, Forsblom C; FinnDiane Study Group, McKnight AJ, Maxwell AP, Brennan E, Sadlier D, Godson C, Groop PH, Hirschhorn JN, Florez JC.

Diabetes. 2015 Dec;64(12):4238-46. doi: 10.2337/db15-0254. Epub 2015 Aug 25.

26.

Genetics of diabetic nephropathy: a long road of discovery.

McKnight AJ, Duffy S, Maxwell AP.

Curr Diab Rep. 2015 Jul;15(7):41. doi: 10.1007/s11892-015-0610-9. Review.

PMID:
25971618
27.

Distinct methylation patterns in genes that affect mitochondrial function are associated with kidney disease in blood-derived DNA from individuals with Type 1 diabetes.

Swan EJ, Maxwell AP, McKnight AJ.

Diabet Med. 2015 Aug;32(8):1110-5. doi: 10.1111/dme.12775. Epub 2015 May 10.

PMID:
25850930
28.

Genetic risk factors affecting mitochondrial function are associated with kidney disease in people with Type 1 diabetes.

Swan EJ, Salem RM, Sandholm N, Tarnow L, Rossing P, Lajer M, Groop PH, Maxwell AP, McKnight AJ; GENIE Consortium.

Diabet Med. 2015 Aug;32(8):1104-9. doi: 10.1111/dme.12763. Epub 2015 Apr 13.

29.

Genetic studies of body mass index yield new insights for obesity biology.

Locke AE, Kahali B, Berndt SI, Justice AE, Pers TH, Day FR, Powell C, Vedantam S, Buchkovich ML, Yang J, Croteau-Chonka DC, Esko T, Fall T, Ferreira T, Gustafsson S, Kutalik Z, Luan J, Mägi R, Randall JC, Winkler TW, Wood AR, Workalemahu T, Faul JD, Smith JA, Zhao JH, Zhao W, Chen J, Fehrmann R, Hedman ÅK, Karjalainen J, Schmidt EM, Absher D, Amin N, Anderson D, Beekman M, Bolton JL, Bragg-Gresham JL, Buyske S, Demirkan A, Deng G, Ehret GB, Feenstra B, Feitosa MF, Fischer K, Goel A, Gong J, Jackson AU, Kanoni S, Kleber ME, Kristiansson K, Lim U, Lotay V, Mangino M, Leach IM, Medina-Gomez C, Medland SE, Nalls MA, Palmer CD, Pasko D, Pechlivanis S, Peters MJ, Prokopenko I, Shungin D, Stančáková A, Strawbridge RJ, Sung YJ, Tanaka T, Teumer A, Trompet S, van der Laan SW, van Setten J, Van Vliet-Ostaptchouk JV, Wang Z, Yengo L, Zhang W, Isaacs A, Albrecht E, Ärnlöv J, Arscott GM, Attwood AP, Bandinelli S, Barrett A, Bas IN, Bellis C, Bennett AJ, Berne C, Blagieva R, Blüher M, Böhringer S, Bonnycastle LL, Böttcher Y, Boyd HA, Bruinenberg M, Caspersen IH, Chen YI, Clarke R, Daw EW, de Craen AJM, Delgado G, Dimitriou M, Doney ASF, Eklund N, Estrada K, Eury E, Folkersen L, Fraser RM, Garcia ME, Geller F, Giedraitis V, Gigante B, Go AS, Golay A, Goodall AH, Gordon SD, Gorski M, Grabe HJ, Grallert H, Grammer TB, Gräßler J, Grönberg H, Groves CJ, Gusto G, Haessler J, Hall P, Haller T, Hallmans G, Hartman CA, Hassinen M, Hayward C, Heard-Costa NL, Helmer Q, Hengstenberg C, Holmen O, Hottenga JJ, James AL, Jeff JM, Johansson Å, Jolley J, Juliusdottir T, Kinnunen L, Koenig W, Koskenvuo M, Kratzer W, Laitinen J, Lamina C, Leander K, Lee NR, Lichtner P, Lind L, Lindström J, Lo KS, Lobbens S, Lorbeer R, Lu Y, Mach F, Magnusson PKE, Mahajan A, McArdle WL, McLachlan S, Menni C, Merger S, Mihailov E, Milani L, Moayyeri A, Monda KL, Morken MA, Mulas A, Müller G, Müller-Nurasyid M, Musk AW, Nagaraja R, Nöthen MM, Nolte IM, Pilz S, Rayner NW, Renstrom F, Rettig R, Ried JS, Ripke S, Robertson NR, Rose LM, Sanna S, Scharnagl H, Scholtens S, Schumacher FR, Scott WR, Seufferlein T, Shi J, Smith AV, Smolonska J, Stanton AV, Steinthorsdottir V, Stirrups K, Stringham HM, Sundström J, Swertz MA, Swift AJ, Syvänen AC, Tan ST, Tayo BO, Thorand B, Thorleifsson G, Tyrer JP, Uh HW, Vandenput L, Verhulst FC, Vermeulen SH, Verweij N, Vonk JM, Waite LL, Warren HR, Waterworth D, Weedon MN, Wilkens LR, Willenborg C, Wilsgaard T, Wojczynski MK, Wong A, Wright AF, Zhang Q; LifeLines Cohort Study, Brennan EP, Choi M, Dastani Z, Drong AW, Eriksson P, Franco-Cereceda A, Gådin JR, Gharavi AG, Goddard ME, Handsaker RE, Huang J, Karpe F, Kathiresan S, Keildson S, Kiryluk K, Kubo M, Lee JY, Liang L, Lifton RP, Ma B, McCarroll SA, McKnight AJ, Min JL, Moffatt MF, Montgomery GW, Murabito JM, Nicholson G, Nyholt DR, Okada Y, Perry JRB, Dorajoo R, Reinmaa E, Salem RM, Sandholm N, Scott RA, Stolk L, Takahashi A, Tanaka T, van 't Hooft FM, Vinkhuyzen AAE, Westra HJ, Zheng W, Zondervan KT; ADIPOGen Consortium; AGEN-BMI Working Group; CARDIOGRAMplusC4D Consortium; CKDGen Consortium; GLGC; ICBP; MAGIC Investigators; MuTHER Consortium; MIGen Consortium; PAGE Consortium; ReproGen Consortium; GENIE Consortium; International Endogene Consortium, Heath AC, Arveiler D, Bakker SJL, Beilby J, Bergman RN, Blangero J, Bovet P, Campbell H, Caulfield MJ, Cesana G, Chakravarti A, Chasman DI, Chines PS, Collins FS, Crawford DC, Cupples LA, Cusi D, Danesh J, de Faire U, den Ruijter HM, Dominiczak AF, Erbel R, Erdmann J, Eriksson JG, Farrall M, Felix SB, Ferrannini E, Ferrières J, Ford I, Forouhi NG, Forrester T, Franco OH, Gansevoort RT, Gejman PV, Gieger C, Gottesman O, Gudnason V, Gyllensten U, Hall AS, Harris TB, Hattersley AT, Hicks AA, Hindorff LA, Hingorani AD, Hofman A, Homuth G, Hovingh GK, Humphries SE, Hunt SC, Hyppönen E, Illig T, Jacobs KB, Jarvelin MR, Jöckel KH, Johansen B, Jousilahti P, Jukema JW, Jula AM, Kaprio J, Kastelein JJP, Keinanen-Kiukaanniemi SM, Kiemeney LA, Knekt P, Kooner JS, Kooperberg C, Kovacs P, Kraja AT, Kumari M, Kuusisto J, Lakka TA, Langenberg C, Marchand LL, Lehtimäki T, Lyssenko V, Männistö S, Marette A, Matise TC, McKenzie CA, McKnight B, Moll FL, Morris AD, Morris AP, Murray JC, Nelis M, Ohlsson C, Oldehinkel AJ, Ong KK, Madden PAF, Pasterkamp G, Peden JF, Peters A, Postma DS, Pramstaller PP, Price JF, Qi L, Raitakari OT, Rankinen T, Rao DC, Rice TK, Ridker PM, Rioux JD, Ritchie MD, Rudan I, Salomaa V, Samani NJ, Saramies J, Sarzynski MA, Schunkert H, Schwarz PEH, Sever P, Shuldiner AR, Sinisalo J, Stolk RP, Strauch K, Tönjes A, Trégouët DA, Tremblay A, Tremoli E, Virtamo J, Vohl MC, Völker U, Waeber G, Willemsen G, Witteman JC, Zillikens MC, Adair LS, Amouyel P, Asselbergs FW, Assimes TL, Bochud M, Boehm BO, Boerwinkle E, Bornstein SR, Bottinger EP, Bouchard C, Cauchi S, Chambers JC, Chanock SJ, Cooper RS, de Bakker PIW, Dedoussis G, Ferrucci L, Franks PW, Froguel P, Groop LC, Haiman CA, Hamsten A, Hui J, Hunter DJ, Hveem K, Kaplan RC, Kivimaki M, Kuh D, Laakso M, Liu Y, Martin NG, März W, Melbye M, Metspalu A, Moebus S, Munroe PB, Njølstad I, Oostra BA, Palmer CNA, Pedersen NL, Perola M, Pérusse L, Peters U, Power C, Quertermous T, Rauramaa R, Rivadeneira F, Saaristo TE, Saleheen D, Sattar N, Schadt EE, Schlessinger D, Slagboom PE, Snieder H, Spector TD, Thorsteinsdottir U, Stumvoll M, Tuomilehto J, Uitterlinden AG, Uusitupa M, van der Harst P, Walker M, Wallaschofski H, Wareham NJ, Watkins H, Weir DR, Wichmann HE, Wilson JF, Zanen P, Borecki IB, Deloukas P, Fox CS, Heid IM, O'Connell JR, Strachan DP, Stefansson K, van Duijn CM, Abecasis GR, Franke L, Frayling TM, McCarthy MI, Visscher PM, Scherag A, Willer CJ, Boehnke M, Mohlke KL, Lindgren CM, Beckmann JS, Barroso I, North KE, Ingelsson E, Hirschhorn JN, Loos RJF, Speliotes EK.

Nature. 2015 Feb 12;518(7538):197-206. doi: 10.1038/nature14177.

30.

New genetic loci link adipose and insulin biology to body fat distribution.

Shungin D, Winkler TW, Croteau-Chonka DC, Ferreira T, Locke AE, Mägi R, Strawbridge RJ, Pers TH, Fischer K, Justice AE, Workalemahu T, Wu JMW, Buchkovich ML, Heard-Costa NL, Roman TS, Drong AW, Song C, Gustafsson S, Day FR, Esko T, Fall T, Kutalik Z, Luan J, Randall JC, Scherag A, Vedantam S, Wood AR, Chen J, Fehrmann R, Karjalainen J, Kahali B, Liu CT, Schmidt EM, Absher D, Amin N, Anderson D, Beekman M, Bragg-Gresham JL, Buyske S, Demirkan A, Ehret GB, Feitosa MF, Goel A, Jackson AU, Johnson T, Kleber ME, Kristiansson K, Mangino M, Leach IM, Medina-Gomez C, Palmer CD, Pasko D, Pechlivanis S, Peters MJ, Prokopenko I, Stančáková A, Sung YJ, Tanaka T, Teumer A, Van Vliet-Ostaptchouk JV, Yengo L, Zhang W, Albrecht E, Ärnlöv J, Arscott GM, Bandinelli S, Barrett A, Bellis C, Bennett AJ, Berne C, Blüher M, Böhringer S, Bonnet F, Böttcher Y, Bruinenberg M, Carba DB, Caspersen IH, Clarke R, Daw EW, Deelen J, Deelman E, Delgado G, Doney AS, Eklund N, Erdos MR, Estrada K, Eury E, Friedrich N, Garcia ME, Giedraitis V, Gigante B, Go AS, Golay A, Grallert H, Grammer TB, Gräßler J, Grewal J, Groves CJ, Haller T, Hallmans G, Hartman CA, Hassinen M, Hayward C, Heikkilä K, Herzig KH, Helmer Q, Hillege HL, Holmen O, Hunt SC, Isaacs A, Ittermann T, James AL, Johansson I, Juliusdottir T, Kalafati IP, Kinnunen L, Koenig W, Kooner IK, Kratzer W, Lamina C, Leander K, Lee NR, Lichtner P, Lind L, Lindström J, Lobbens S, Lorentzon M, Mach F, Magnusson PK, Mahajan A, McArdle WL, Menni C, Merger S, Mihailov E, Milani L, Mills R, Moayyeri A, Monda KL, Mooijaart SP, Mühleisen TW, Mulas A, Müller G, Müller-Nurasyid M, Nagaraja R, Nalls MA, Narisu N, Glorioso N, Nolte IM, Olden M, Rayner NW, Renstrom F, Ried JS, Robertson NR, Rose LM, Sanna S, Scharnagl H, Scholtens S, Sennblad B, Seufferlein T, Sitlani CM, Smith AV, Stirrups K, Stringham HM, Sundström J, Swertz MA, Swift AJ, Syvänen AC, Tayo BO, Thorand B, Thorleifsson G, Tomaschitz A, Troffa C, van Oort FV, Verweij N, Vonk JM, Waite LL, Wennauer R, Wilsgaard T, Wojczynski MK, Wong A, Zhang Q, Zhao JH, Brennan EP, Choi M, Eriksson P, Folkersen L, Franco-Cereceda A, Gharavi AG, Hedman ÅK, Hivert MF, Huang J, Kanoni S, Karpe F, Keildson S, Kiryluk K, Liang L, Lifton RP, Ma B, McKnight AJ, McPherson R, Metspalu A, Min JL, Moffatt MF, Montgomery GW, Murabito JM, Nicholson G, Nyholt DR, Olsson C, Perry JR, Reinmaa E, Salem RM, Sandholm N, Schadt EE, Scott RA, Stolk L, Vallejo EE, Westra HJ, Zondervan KT; ADIPOGen Consortium; CARDIOGRAMplusC4D Consortium; CKDGen Consortium; GEFOS Consortium; GENIE Consortium; GLGC; ICBP; International Endogene Consortium; LifeLines Cohort Study; MAGIC Investigators; MuTHER Consortium; PAGE Consortium; ReproGen Consortium, Amouyel P, Arveiler D, Bakker SJ, Beilby J, Bergman RN, Blangero J, Brown MJ, Burnier M, Campbell H, Chakravarti A, Chines PS, Claudi-Boehm S, Collins FS, Crawford DC, Danesh J, de Faire U, de Geus EJ, Dörr M, Erbel R, Eriksson JG, Farrall M, Ferrannini E, Ferrières J, Forouhi NG, Forrester T, Franco OH, Gansevoort RT, Gieger C, Gudnason V, Haiman CA, Harris TB, Hattersley AT, Heliövaara M, Hicks AA, Hingorani AD, Hoffmann W, Hofman A, Homuth G, Humphries SE, Hyppönen E, Illig T, Jarvelin MR, Johansen B, Jousilahti P, Jula AM, Kaprio J, Kee F, Keinanen-Kiukaanniemi SM, Kooner JS, Kooperberg C, Kovacs P, Kraja AT, Kumari M, Kuulasmaa K, Kuusisto J, Lakka TA, Langenberg C, Le Marchand L, Lehtimäki T, Lyssenko V, Männistö S, Marette A, Matise TC, McKenzie CA, McKnight B, Musk AW, Möhlenkamp S, Morris AD, Nelis M, Ohlsson C, Oldehinkel AJ, Ong KK, Palmer LJ, Penninx BW, Peters A, Pramstaller PP, Raitakari OT, Rankinen T, Rao DC, Rice TK, Ridker PM, Ritchie MD, Rudan I, Salomaa V, Samani NJ, Saramies J, Sarzynski MA, Schwarz PE, Shuldiner AR, Staessen JA, Steinthorsdottir V, Stolk RP, Strauch K, Tönjes A, Tremblay A, Tremoli E, Vohl MC, Völker U, Vollenweider P, Wilson JF, Witteman JC, Adair LS, Bochud M, Boehm BO, Bornstein SR, Bouchard C, Cauchi S, Caulfield MJ, Chambers JC, Chasman DI, Cooper RS, Dedoussis G, Ferrucci L, Froguel P, Grabe HJ, Hamsten A, Hui J, Hveem K, Jöckel KH, Kivimaki M, Kuh D, Laakso M, Liu Y, März W, Munroe PB, Njølstad I, Oostra BA, Palmer CN, Pedersen NL, Perola M, Pérusse L, Peters U, Power C, Quertermous T, Rauramaa R, Rivadeneira F, Saaristo TE, Saleheen D, Sinisalo J, Slagboom PE, Snieder H, Spector TD, Stefansson K, Stumvoll M, Tuomilehto J, Uitterlinden AG, Uusitupa M, van der Harst P, Veronesi G, Walker M, Wareham NJ, Watkins H, Wichmann HE, Abecasis GR, Assimes TL, Berndt SI, Boehnke M, Borecki IB, Deloukas P, Franke L, Frayling TM, Groop LC, Hunter DJ, Kaplan RC, O'Connell JR, Qi L, Schlessinger D, Strachan DP, Thorsteinsdottir U, van Duijn CM, Willer CJ, Visscher PM, Yang J, Hirschhorn JN, Zillikens MC, McCarthy MI, Speliotes EK, North KE, Fox CS, Barroso I, Franks PW, Ingelsson E, Heid IM, Loos RJ, Cupples LA, Morris AP, Lindgren CM, Mohlke KL.

Nature. 2015 Feb 12;518(7538):187-196. doi: 10.1038/nature14132.

31.

Next-generation sequencing of the mitochondrial genome and association with IgA nephropathy in a renal transplant population.

Douglas AP, Vance DR, Kenny EM, Morris DW, Maxwell AP, McKnight AJ.

Sci Rep. 2014 Dec 9;4:7379. doi: 10.1038/srep07379.

32.

SORBS1 gene, a new candidate for diabetic nephropathy: results from a multi-stage genome-wide association study in patients with type 1 diabetes.

Germain M, Pezzolesi MG, Sandholm N, McKnight AJ, Susztak K, Lajer M, Forsblom C, Marre M, Parving HH, Rossing P, Toppila I, Skupien J, Roussel R, Ko YA, Ledo N, Folkersen L, Civelek M, Maxwell AP, Tregouet DA, Groop PH, Tarnow L, Hadjadj S.

Diabetologia. 2015 Mar;58(3):543-8. doi: 10.1007/s00125-014-3459-6. Epub 2014 Dec 6.

33.

Epigenome-wide association study for Parkinson's disease.

Moore K, McKnight AJ, Craig D, O'Neill F.

Neuromolecular Med. 2014 Dec;16(4):845-55. doi: 10.1007/s12017-014-8332-8. Epub 2014 Oct 11.

PMID:
25304910
34.

Whole-mitochondrial genome sequencing in primary open-angle glaucoma using massively parallel sequencing identifies novel and known pathogenic variants.

Sundaresan P, Simpson DA, Sambare C, Duffy S, Lechner J, Dastane A, Dervan EW, Vallabh N, Chelerkar V, Deshpande M, O'Brien C, McKnight AJ, Willoughby CE.

Genet Med. 2015 Apr;17(4):279-84. doi: 10.1038/gim.2014.121. Epub 2014 Sep 18.

PMID:
25232845
35.

Genetic polymorphisms and kidney transplant outcomes.

Chand S, McKnight AJ, Borrows R.

Curr Opin Nephrol Hypertens. 2014 Nov;23(6):605-10. doi: 10.1097/MNH.0000000000000068. Review.

PMID:
25188274
36.

β cell glucotoxic-associated single nucleotide polymorphisms in impaired glucose tolerance and new-onset diabetes after transplantation.

Chand S, Shabir S, Chan W, McCaughan JA, McKnight AJ, Maxwell AP, Borrows R.

Transplantation. 2014 Aug 15;98(3):e19-20. doi: 10.1097/TP.0000000000000268. No abstract available.

PMID:
25089340
37.

Genetic and epigenetic factors influencing chronic kidney disease.

Smyth LJ, Duffy S, Maxwell AP, McKnight AJ.

Am J Physiol Renal Physiol. 2014 Oct 1;307(7):F757-76. doi: 10.1152/ajprenal.00306.2014. Epub 2014 Jul 30. Review.

38.

Novel genetic susceptibility loci for diabetic end-stage renal disease identified through robust naive Bayes classification.

Sambo F, Malovini A, Sandholm N, Stavarachi M, Forsblom C, Mäkinen VP, Harjutsalo V, Lithovius R, Gordin D, Parkkonen M, Saraheimo M, Thorn LM, Tolonen N, Wadén J, He B, Osterholm AM, Tuomilehto J, Lajer M, Salem RM, McKnight AJ; GENIE Consortium, Tarnow L, Panduru NM, Barbarini N, Di Camillo B, Toffolo GM, Tryggvason K, Bellazzi R, Cobelli C; FinnDiane Study Group, Groop PH.

Diabetologia. 2014 Aug;57(8):1611-22. doi: 10.1007/s00125-014-3256-2. Epub 2014 May 29.

PMID:
24871321
39.

Genetic and epigenetic risk factors for diabetic kidney disease.

McKnight AJ, McKay GJ, Maxwell AP.

Adv Chronic Kidney Dis. 2014 May;21(3):287-96. doi: 10.1053/j.ackd.2014.03.010. Review.

PMID:
24780457
40.

The changing landscape of diabetic kidney disease: new reflections on phenotype, classification, and disease progression to influence future investigative studies and therapeutic trials.

Ho K, McKnight AJ.

Adv Chronic Kidney Dis. 2014 May;21(3):256-9. doi: 10.1053/j.ackd.2014.03.002. No abstract available.

PMID:
24780452
41.

An excess of risk-increasing low-frequency variants can be a signal of polygenic inheritance in complex diseases.

Chan Y, Lim ET, Sandholm N, Wang SR, McKnight AJ, Ripke S; DIAGRAM Consortium; GENIE Consortium; GIANT Consortium; IIBDGC Consortium; PGC Consortium, Daly MJ, Neale BM, Salem RM, Hirschhorn JN.

Am J Hum Genet. 2014 Mar 6;94(3):437-52. doi: 10.1016/j.ajhg.2014.02.006.

42.

Genome-wide association study of urinary albumin excretion rate in patients with type 1 diabetes.

Sandholm N, Forsblom C, Mäkinen VP, McKnight AJ, Osterholm AM, He B, Harjutsalo V, Lithovius R, Gordin D, Parkkonen M, Saraheimo M, Thorn LM, Tolonen N, Wadén J, Tuomilehto J, Lajer M, Ahlqvist E, Möllsten A, Marcovecchio ML, Cooper J, Dunger D, Paterson AD, Zerbini G, Groop L; SUMMIT Consortium, Tarnow L, Maxwell AP, Tryggvason K, Groop PH; FinnDiane Study Group.

Diabetologia. 2014 Jun;57(6):1143-53. doi: 10.1007/s00125-014-3202-3. Epub 2014 Mar 5.

PMID:
24595857
43.

Genetics of new-onset diabetes after transplantation.

McCaughan JA, McKnight AJ, Maxwell AP.

J Am Soc Nephrol. 2014 May;25(5):1037-49. doi: 10.1681/ASN.2013040383. Epub 2013 Dec 5.

44.

DNA hypermethylation and DNA hypomethylation is present at different loci in chronic kidney disease.

Smyth LJ, McKay GJ, Maxwell AP, McKnight AJ.

Epigenetics. 2014 Mar;9(3):366-76. doi: 10.4161/epi.27161. Epub 2013 Nov 19.

45.

Chromosome 2q31.1 associates with ESRD in women with type 1 diabetes.

Sandholm N, McKnight AJ, Salem RM, Brennan EP, Forsblom C, Harjutsalo V, Mäkinen VP, McKay GJ, Sadlier DM, Williams WW, Martin F, Panduru NM, Tarnow L, Tuomilehto J, Tryggvason K, Zerbini G, Comeau ME, Langefeld CD; FIND Consortium, Godson C, Hirschhorn JN, Maxwell AP, Florez JC, Groop PH; FinnDiane Study Group and the GENIE Consortium.

J Am Soc Nephrol. 2013 Oct;24(10):1537-43. doi: 10.1681/ASN.2012111122. Epub 2013 Sep 12.

46.

Caveolin-1 single nucleotide polymorphism in antineutrophil cytoplasmic antibody associated vasculitis.

Chand S, Holle JU, Hilhorst M, Simmonds MJ, Smith S, Kamesh L, Hewins P, McKnight AJ, Maxwell AP, Cohen Tervaert JW, Wieczorek S, Harper L, Borrows R.

PLoS One. 2013 Jul 19;8(7):e69022. doi: 10.1371/journal.pone.0069022. Print 2013.

47.

Haplotype association analysis of genes within the WNT signalling pathways in diabetic nephropathy.

Kavanagh DH, Savage DA, Patterson CC, McKnight AJ, Crean JK, Maxwell AP, McKay GJ; Warren 3/UK GoKinD Study Group.

BMC Nephrol. 2013 Jun 18;14:126. doi: 10.1186/1471-2369-14-126.

48.

Femur-fibula-fillet of leg chimeric free flap for sacral-pelvic reconstruction.

McKnight AJ, Lewis VO, Rhines LD, Hanasono MM.

J Plast Reconstr Aesthet Surg. 2013 Dec;66(12):1784-7. doi: 10.1016/j.bjps.2013.05.025. Epub 2013 Jun 2.

PMID:
23735291
49.

CD2AP is associated with end-stage renal disease in patients with type 1 diabetes.

Hyvönen ME, Ihalmo P, Sandholm N, Stavarachi M, Forsblom C, McKnight AJ, Lajer M, Maestroni A, Lewis G, Tarnow L, Maestroni S, Zerbini G, Parving HH, Maxwell AP, Groop PH, Lehtonen S.

Acta Diabetol. 2013 Dec;50(6):887-97. doi: 10.1007/s00592-013-0475-9. Epub 2013 May 17.

PMID:
23681557
50.

Comprehensive investigation of the caveolin 2 gene: resequencing and association for kidney transplant outcomes.

McCaughan JA, Duffy S, O'Hagan T, Courtney AE, Borrows R, Conlon PJ, Maxwell AP, McKnight AJ.

PLoS One. 2013 May 7;8(5):e63358. doi: 10.1371/journal.pone.0063358. Print 2013.

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