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Items: 1 to 50 of 132

1.

Intergenic Splicing between Four Adjacent UGT Genes (2B15, 2B29P2, 2B17, 2B29P1) Gives Rise to Variant UGT Proteins That Inhibit Glucuronidation via Protein-Protein Interactions.

Hu DG, Hulin JA, Wijayakumara DD, McKinnon RA, Mackenzie PI, Meech R.

Mol Pharmacol. 2018 Sep;94(3):938-952. doi: 10.1124/mol.118.111773. Epub 2018 Jun 29.

PMID:
29959221
2.

Cooperative Regulation of Intestinal UDP-Glucuronosyltransferases 1A8, -1A9, and 1A10 by CDX2 and HNF4α Is Mediated by a Novel Composite Regulatory Element.

Mubarokah N, Hulin JA, Mackenzie PI, McKinnon RA, Haines AZ, Hu DG, Meech R.

Mol Pharmacol. 2018 May;93(5):541-552. doi: 10.1124/mol.117.110619. Epub 2018 Mar 8.

PMID:
29519853
3.

Regulation of UDP-Glucuronosyltransferase 2B15 by miR-331-5p in Prostate Cancer Cells Involves Canonical and Noncanonical Target Sites.

Wijayakumara DD, Mackenzie PI, McKinnon RA, Hu DG, Meech R.

J Pharmacol Exp Ther. 2018 Apr;365(1):48-59. doi: 10.1124/jpet.117.245936. Epub 2018 Jan 24.

PMID:
29367276
4.

Biosimilarity and Interchangeability: Principles and Evidence: A Systematic Review.

McKinnon RA, Cook M, Liauw W, Marabani M, Marschner IC, Packer NH, Prins JB.

BioDrugs. 2018 Feb;32(1):27-52. doi: 10.1007/s40259-017-0256-z. Review.

5.

Interventions Targeting the Prescribing and Monitoring of Vancomycin for Hospitalized Patients: A Systematic Review Protocol.

Phillips CJ, Wisdom AJ, McKinnon RA, Woodman RJ, Gordon DL.

Infect Dis Ther. 2017 Dec;6(4):557-563. doi: 10.1007/s40121-017-0177-7. Epub 2017 Oct 27. Review.

6.

Sustained improvement in vancomycin dosing and monitoring post-implementation of guidelines: Results of a three-year follow-up after a multifaceted intervention in an Australian teaching hospital.

Phillips CJ, McKinnon RA, Woodman RJ, Gordon DL.

J Infect Chemother. 2018 Feb;24(2):103-109. doi: 10.1016/j.jiac.2017.09.010. Epub 2017 Oct 14.

PMID:
29037461
7.

Predicting response and toxicity to immune checkpoint inhibitors using routinely available blood and clinical markers.

Hopkins AM, Rowland A, Kichenadasse G, Wiese MD, Gurney H, McKinnon RA, Karapetis CS, Sorich MJ.

Br J Cancer. 2017 Sep 26;117(7):913-920. doi: 10.1038/bjc.2017.274. Epub 2017 Aug 24. Review.

8.

Combination breast cancer chemotherapy with doxorubicin and cyclophosphamide damages bone and bone marrow in a female rat model.

Fan C, Georgiou KR, Morris HA, McKinnon RA, Keefe DMK, Howe PR, Xian CJ.

Breast Cancer Res Treat. 2017 Aug;165(1):41-51. doi: 10.1007/s10549-017-4308-3. Epub 2017 May 26.

PMID:
28550626
9.

Integrated care in cancer: What is it, how is it used and where are the gaps? A textual narrative literature synthesis.

Cortis LJ, Ward PR, McKinnon RA, Koczwara B.

Eur J Cancer Care (Engl). 2017 Jul;26(4). doi: 10.1111/ecc.12689. Epub 2017 Apr 20. Review.

PMID:
28426142
10.

Exemestane and Its Active Metabolite 17-Hydroexemestane Induce UDP-Glucuronosyltransferase (UGT) 2B17 Expression in Breast Cancer Cells.

Chanawong A, Mackenzie PI, McKinnon RA, Hu DG, Meech R.

J Pharmacol Exp Ther. 2017 Jun;361(3):482-491. doi: 10.1124/jpet.117.240317. Epub 2017 Apr 12.

11.

Regulation of UDP-Glucuronosyltransferases UGT2B4 and UGT2B7 by MicroRNAs in Liver Cancer Cells.

Wijayakumara DD, Mackenzie PI, McKinnon RA, Hu DG, Meech R.

J Pharmacol Exp Ther. 2017 Jun;361(3):386-397. doi: 10.1124/jpet.116.239707. Epub 2017 Apr 7.

12.

The Routine Clinical use of Pharmacogenetic Tests: What it Will Require?

Dias MM, Sorich MJ, Rowland A, Wiese MD, McKinnon RA.

Pharm Res. 2017 Aug;34(8):1544-1550. doi: 10.1007/s11095-017-2128-0. Epub 2017 Feb 24. Review.

PMID:
28236061
13.

Role of the Pharmacist for Improving Self-care and Outcomes in Heart Failure.

Parajuli DR, Franzon J, McKinnon RA, Shakib S, Clark RA.

Curr Heart Fail Rep. 2017 Apr;14(2):78-86. doi: 10.1007/s11897-017-0323-2. Review.

PMID:
28233258
14.

Inhibition of human UDP-glucuronosyltransferase enzymes by lapatinib, pazopanib, regorafenib and sorafenib: Implications for hyperbilirubinemia.

Miners JO, Chau N, Rowland A, Burns K, McKinnon RA, Mackenzie PI, Tucker GT, Knights KM, Kichenadasse G.

Biochem Pharmacol. 2017 Apr 1;129:85-95. doi: 10.1016/j.bcp.2017.01.002. Epub 2017 Jan 6.

PMID:
28065859
15.

Novel Nine-Exon AR Transcripts (Exon 1/Exon 1b/Exons 2-8) in Normal and Cancerous Breast and Prostate Cells.

Hu DG, McKinnon RA, Hulin JA, Mackenzie PI, Meech R.

Int J Mol Sci. 2016 Dec 27;18(1). pii: E40. doi: 10.3390/ijms18010040.

16.

Supplementation with Brazil nuts and green tea extract regulates targeted biomarkers related to colorectal cancer risk in humans.

Hu Y, McIntosh GH, Le Leu RK, Somashekar R, Meng XQ, Gopalsamy G, Bambaca L, McKinnon RA, Young GP.

Br J Nutr. 2016 Dec;116(11):1901-1911. doi: 10.1017/S0007114516003937. Epub 2016 Dec 7.

PMID:
27923410
17.

Kinase inhibitor pharmacokinetics: comprehensive summary and roadmap for addressing inter-individual variability in exposure.

Rowland A, van Dyk M, Mangoni AA, Miners JO, McKinnon RA, Wiese MD, Rowland A, Kichenadasse G, Gurney H, Sorich MJ.

Expert Opin Drug Metab Toxicol. 2017 Jan;13(1):31-49. Epub 2016 Sep 1. Review.

PMID:
27561659
18.

A Fragment-Based Approach for the Computational Prediction of the Nonspecific Binding of Drugs to Hepatic Microsomes.

Nair PC, McKinnon RA, Miners JO.

Drug Metab Dispos. 2016 Nov;44(11):1794-1798. Epub 2016 Aug 19.

19.

A novel approach for the simultaneous quantification of 18 small molecule kinase inhibitors in human plasma: A platform for optimised KI dosing.

van Dyk M, Miners JO, Kichenadasse G, McKinnon RA, Rowland A.

J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Oct 15;1033-1034:17-26. doi: 10.1016/j.jchromb.2016.07.046. Epub 2016 Jul 26.

PMID:
27521531
20.

In vitro metabolism of the anti-inflammatory clerodane diterpenoid polyandric acid A and its hydrolysis product by human liver microsomes and recombinant cytochrome P450 and UDP-glucuronosyltransferase enzymes.

Bendikov MY, Miners JO, Simpson BS, Elliot DJ, Semple SJ, Claudie DJ, McKinnon RA, Gillam EMJ, Sykes MJ.

Xenobiotica. 2017 Jun;47(6):461-469. doi: 10.1080/00498254.2016.1203041. Epub 2016 Jul 14.

PMID:
27412850
21.

Cytochrome P450 structure-function: insights from molecular dynamics simulations.

Nair PC, McKinnon RA, Miners JO.

Drug Metab Rev. 2016 Aug;48(3):434-52. doi: 10.1080/03602532.2016.1178771. Epub 2016 May 10. Review.

PMID:
27167388
22.

The impact of a pilot continuing professional development module on hospital pharmacists' preparedness to provide contemporary advice on the clinical use of vancomycin.

Phillips CJ, Wisdom AJ, Eaton VS, Woodman RJ, McKinnon RA.

Springerplus. 2016 Mar 15;5:331. doi: 10.1186/s40064-016-1966-2. eCollection 2016.

23.

Genetic polymorphisms of human UDP-glucuronosyltransferase (UGT) genes and cancer risk.

Hu DG, Mackenzie PI, McKinnon RA, Meech R.

Drug Metab Rev. 2016;48(1):47-69. doi: 10.3109/03602532.2015.1131292. Epub 2016 Feb 1. Review.

PMID:
26828111
24.

Meta-analysis comparing the efficacy of anti-EGFR monoclonal antibody therapy between KRAS G13D and other KRAS mutant metastatic colorectal cancer tumours.

Rowland A, Dias MM, Wiese MD, Kichenadasse G, McKinnon RA, Karapetis CS, Sorich MJ.

Eur J Cancer. 2016 Mar;55:122-30. doi: 10.1016/j.ejca.2015.11.025. Epub 2016 Jan 23. Review.

PMID:
26812186
25.

Obesity-Related Policy/Environmental Interventions: A Systematic Review of Economic Analyses.

McKinnon RA, Siddiqi SM, Chaloupka FJ, Mancino L, Prasad K.

Am J Prev Med. 2016 Apr;50(4):543-549. doi: 10.1016/j.amepre.2015.10.021. Epub 2015 Dec 18. Review.

PMID:
26707464
26.

Reply: Comment on 'Meta-analysis of BRAF mutation as a predictive biomarker of benefit from anti-EGFR monoclonal-antibody therapy for RAS wild-type metastatic colorectal cancer'.

Rowland A, Dias MM, Wiese MD, Kichenadasse G, McKinnon RA, Karapetis CS, Sorich MJ.

Br J Cancer. 2015 Dec 1;113(11):1635. doi: 10.1038/bjc.2015.325. Epub 2015 Sep 10. No abstract available.

27.

Let's Move! Cities, Towns and Counties: Working with Local Elected Officials to Improve Community Food and Physical Activity Environments.

McKinnon RA, Wiedt T, Hoffnagle E, Shrimplin S; Extended Let's Move! Cities, Towns and Counties Team.

Public Health Rep. 2015 Sep-Oct;130(5):426-30. No abstract available.

28.

Impact of Histone Deacetylase Inhibitors on microRNA Expression and Cancer Therapy: A Review.

Ali SR, Humphreys KJ, McKinnon RA, Michael MZ.

Drug Dev Res. 2015 Sep;76(6):296-317. doi: 10.1002/ddr.21268. Epub 2015 Aug 25. Review.

PMID:
26303212
29.

Insights into the UDP-sugar selectivities of human UDP-glycosyltransferases (UGT): a molecular modeling perspective.

Nair PC, Meech R, Mackenzie PI, McKinnon RA, Miners JO.

Drug Metab Rev. 2015 Aug;47(3):335-45. doi: 10.3109/03602532.2015.1071835. Epub 2015 Aug 3. Review.

PMID:
26289097
30.

Insights into the UDP-sugar selectivities of human UDP-glycosyltransferases (UGT): a molecular modeling perspective.

Nair PC, Meech R, Mackenzie PI, McKinnon RA, Miners JO.

Drug Metab Rev. 2015 Aug 3:1-11. [Epub ahead of print]

PMID:
26234632
31.

Regulation of Human UGT2B15 and UGT2B17 by miR-376c in Prostate Cancer Cell Lines.

Wijayakumara DD, Hu DG, Meech R, McKinnon RA, Mackenzie PI.

J Pharmacol Exp Ther. 2015 Sep;354(3):417-25. doi: 10.1124/jpet.115.226118. Epub 2015 Jul 10.

32.

Combination chemotherapy with cyclophosphamide, epirubicin and 5-fluorouracil causes trabecular bone loss, bone marrow cell depletion and marrow adiposity in female rats.

Fan C, Georgiou KR, McKinnon RA, Keefe DM, Howe PR, Xian CJ.

J Bone Miner Metab. 2016 May;34(3):277-90. doi: 10.1007/s00774-015-0679-x. Epub 2015 Jun 9.

PMID:
26056019
33.

Meta-analysis of BRAF mutation as a predictive biomarker of benefit from anti-EGFR monoclonal antibody therapy for RAS wild-type metastatic colorectal cancer.

Rowland A, Dias MM, Wiese MD, Kichenadasse G, McKinnon RA, Karapetis CS, Sorich MJ.

Br J Cancer. 2015 Jun 9;112(12):1888-94. doi: 10.1038/bjc.2015.173. Epub 2015 May 19. Review.

34.

Induction of UDP-glucuronosyltransferase 2B15 gene expression by the major active metabolites of tamoxifen, 4-hydroxytamoxifen and endoxifen, in breast cancer cells.

Chanawong A, Hu DG, Meech R, Mackenzie PI, McKinnon RA.

Drug Metab Dispos. 2015 Jun;43(6):889-97. doi: 10.1124/dmd.114.062935. Epub 2015 Mar 20.

35.

Induction of human UDP-Glucuronosyltransferase 2B7 gene expression by cytotoxic anticancer drugs in liver cancer HepG2 cells.

Hu DG, Mackenzie PI, Lu L, Meech R, McKinnon RA.

Drug Metab Dispos. 2015 May;43(5):660-8. doi: 10.1124/dmd.114.062380. Epub 2015 Feb 23.

36.

Opportunities for public health to increase physical activity among youths.

Piercy KL, Dorn JM, Fulton JE, Janz KF, Lee SM, McKinnon RA, Pate RR, Pfeiffer KA, Young DR, Troiano RP, Lavizzo-Mourey R.

Am J Public Health. 2015 Mar;105(3):421-6. doi: 10.2105/AJPH.2014.302325. Epub 2015 Jan 20.

37.

Geospatial and Contextual Approaches to Energy Balance and Health.

Berrigan D, Hipp JA, Hurvitz PM, James P, Jankowska MM, Kerr J, Laden F, Leonard T, McKinnon RA, Powell-Wiley TM, Tarlov E, Zenk SN; TREC Spatial and Contextual Measures and Modeling Work Group.

Ann GIS. 2015;21(2):157-168. Epub 2015 Mar 13.

38.

A novel function for UDP glycosyltransferase 8: galactosidation of bile acids.

Meech R, Mubarokah N, Shivasami A, Rogers A, Nair PC, Hu DG, McKinnon RA, Mackenzie PI.

Mol Pharmacol. 2015;87(3):442-50. doi: 10.1124/mol.114.093823. Epub 2014 Dec 17.

39.

miR-18a inhibits CDC42 and plays a tumour suppressor role in colorectal cancer cells.

Humphreys KJ, McKinnon RA, Michael MZ.

PLoS One. 2014 Nov 7;9(11):e112288. doi: 10.1371/journal.pone.0112288. eCollection 2014.

40.

Transcriptional regulation of human UDP-glucuronosyltransferase genes.

Hu DG, Meech R, McKinnon RA, Mackenzie PI.

Drug Metab Rev. 2014 Nov;46(4):421-58. doi: 10.3109/03602532.2014.973037. Epub 2014 Oct 22. Review.

PMID:
25336387
41.

CYP2C19 genotype has a greater effect on adverse cardiovascular outcomes following percutaneous coronary intervention and in Asian populations treated with clopidogrel: a meta-analysis.

Sorich MJ, Rowland A, McKinnon RA, Wiese MD.

Circ Cardiovasc Genet. 2014 Dec;7(6):895-902. doi: 10.1161/CIRCGENETICS.114.000669. Epub 2014 Sep 25.

PMID:
25258374
42.

Extended RAS mutations and anti-EGFR monoclonal antibody survival benefit in metastatic colorectal cancer: a meta-analysis of randomized, controlled trials.

Sorich MJ, Wiese MD, Rowland A, Kichenadasse G, McKinnon RA, Karapetis CS.

Ann Oncol. 2015 Jan;26(1):13-21. doi: 10.1093/annonc/mdu378. Epub 2014 Aug 12. Review.

PMID:
25115304
43.

News from the NIH: research to evaluate "natural experiments" related to obesity and diabetes.

Hunter CM, McKinnon RA, Esposito L.

Transl Behav Med. 2014 Jun;4(2):127-9. doi: 10.1007/s13142-013-0250-z. No abstract available.

44.

The effect of the UGT1A1*28 allele on survival after irinotecan-based chemotherapy: a collaborative meta-analysis.

Dias MM, Pignon JP, Karapetis CS, Boige V, Glimelius B, Kweekel DM, Lara PN, Laurent-Puig P, Martinez-Balibrea E, Páez D, Punt CJ, Redman MW, Toffoli G, Wadelius M, McKinnon RA, Sorich MJ.

Pharmacogenomics J. 2014 Oct;14(5):424-31. doi: 10.1038/tpj.2014.16. Epub 2014 Apr 8.

PMID:
24709690
45.

Polymorphisms and haplotypes of the UDP-glucuronosyltransferase 2B7 gene promoter.

Hu DG, Meech R, Lu L, McKinnon RA, Mackenzie PI.

Drug Metab Dispos. 2014 May;42(5):854-62. doi: 10.1124/dmd.113.056630. Epub 2014 Feb 21.

46.

Polyandric acid A, a clerodane diterpenoid from the Australian medicinal plant Dodonaea polyandra, attenuates pro-inflammatory cytokine secretion in vitro and in vivo.

Simpson BS, Luo X, Costabile M, Caughey GE, Wang J, Claudie DJ, McKinnon RA, Semple SJ.

J Nat Prod. 2014 Jan 24;77(1):85-91. doi: 10.1021/np400704b. Epub 2014 Jan 8.

PMID:
24400858
47.

Dietary assessment in food environment research: a systematic review.

Kirkpatrick SI, Reedy J, Butler EN, Dodd KW, Subar AF, Thompson FE, McKinnon RA.

Am J Prev Med. 2014 Jan;46(1):94-102. doi: 10.1016/j.amepre.2013.08.015. Review.

48.

Sugar-sweetened beverage consumption in the U.S.: novel assessment methodology.

Miller PE, McKinnon RA, Krebs-Smith SM, Subar AF, Chriqui J, Kahle L, Reedy J.

Am J Prev Med. 2013 Oct;45(4):416-21. doi: 10.1016/j.amepre.2013.05.014.

PMID:
24050417
49.

Exploration of the perceptions, barriers and drivers of pharmacogenomics practice among hospital pharmacists in Adelaide, South Australia.

Dias MM, Ward HM, Sorich MJ, McKinnon RA.

Pharmacogenomics J. 2014 Jun;14(3):235-40. doi: 10.1038/tpj.2013.31. Epub 2013 Sep 10.

PMID:
24018620
50.

Learning from both sides: Experiences and opportunities in the investigation of Australian aboriginal medicinal plants.

Simpson BS, Claudie DJ, Smith NM, McKinnon RA, Semple SJ.

J Pharm Pharm Sci. 2013;16(2):259-71. Review.

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