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Items: 39


Platelet-activating factor (PAF) mediates NLRP3-NEK7 inflammasome induction independently of PAFR.

Deng M, Guo H, Tam JW, Johnson BM, Brickey WJ, New JS, Lenox A, Shi H, Golenbock DT, Koller BH, McKinnon KP, Beutler B, Ting JP.

J Exp Med. 2019 Dec 2;216(12):2838-2853. doi: 10.1084/jem.20190111. Epub 2019 Sep 26.


A nanoparticle-incorporated STING activator enhances antitumor immunity in PD-L1-insensitive models of triple-negative breast cancer.

Cheng N, Watkins-Schulz R, Junkins RD, David CN, Johnson BM, Montgomery SA, Peine KJ, Darr DB, Yuan H, McKinnon KP, Liu Q, Miao L, Huang L, Bachelder EM, Ainslie KM, Ting JP.

JCI Insight. 2018 Nov 15;3(22). pii: 120638. doi: 10.1172/jci.insight.120638.


Impaired bone marrow B-cell development in mice with a bronchiolitis obliterans model of cGVHD.

Kolupaev OV, Dant TA, Bommiasamy H, Bruce DW, Fowler KA, Tilley SL, McKinnon KP, Sarantopoulos S, Blazar BR, Coghill JM, Serody JS.

Blood Adv. 2018 Sep 25;2(18):2307-2319. doi: 10.1182/bloodadvances.2017014977. Epub 2018 Sep 18.


Properly folded and functional PorB from Neisseria gonorrhoeae inhibits dendritic cell stimulation of CD4+ T cell proliferation.

Zhu W, Tomberg J, Knilans KJ, Anderson JE, McKinnon KP, Sempowski GD, Nicholas RA, Duncan JA.

J Biol Chem. 2018 Jul 13;293(28):11218-11229. doi: 10.1074/jbc.RA117.001209. Epub 2018 May 11.


Treg depletion potentiates checkpoint inhibition in claudin-low breast cancer.

Taylor NA, Vick SC, Iglesia MD, Brickey WJ, Midkiff BR, McKinnon KP, Reisdorf S, Anders CK, Carey LA, Parker JS, Perou CM, Vincent BG, Serody JS.

J Clin Invest. 2017 Sep 1;127(9):3472-3483. doi: 10.1172/JCI90499. Epub 2017 Aug 21.


Antigen-capturing nanoparticles improve the abscopal effect and cancer immunotherapy.

Min Y, Roche KC, Tian S, Eblan MJ, McKinnon KP, Caster JM, Chai S, Herring LE, Zhang L, Zhang T, DeSimone JM, Tepper JE, Vincent BG, Serody JS, Wang AZ.

Nat Nanotechnol. 2017 Sep;12(9):877-882. doi: 10.1038/nnano.2017.113. Epub 2017 Jun 26.


T-cell expression of AhR inhibits the maintenance of pTreg cells in the gastrointestinal tract in acute GVHD.

Dant TA, Lin KL, Bruce DW, Montgomery SA, Kolupaev OV, Bommiasamy H, Bixby LM, Woosley JT, McKinnon KP, Gonzalez FJ, Blazar BR, Vincent BG, Coghill JM, Serody JS.

Blood. 2017 Jul 20;130(3):348-359. doi: 10.1182/blood-2016-08-734244. Epub 2017 May 26.


Type 2 innate lymphoid cells treat and prevent acute gastrointestinal graft-versus-host disease.

Bruce DW, Stefanski HE, Vincent BG, Dant TA, Reisdorf S, Bommiasamy H, Serody DA, Wilson JE, McKinnon KP, Shlomchik WD, Armistead PM, Ting JPY, Woosley JT, Blazar BR, Zaiss DMW, McKenzie ANJ, Coghill JM, Serody JS.

J Clin Invest. 2017 May 1;127(5):1813-1825. doi: 10.1172/JCI91816. Epub 2017 Apr 4.


Towards programming immune tolerance through geometric manipulation of phosphatidylserine.

Roberts RA, Eitas TK, Byrne JD, Johnson BM, Short PJ, McKinnon KP, Reisdorf S, Luft JC, DeSimone JM, Ting JP.

Biomaterials. 2015 Dec;72:1-10. doi: 10.1016/j.biomaterials.2015.08.040. Epub 2015 Aug 20.


Source and Purity of Dengue-Viral Preparations Impact Requirement for Enhancing Antibody to Induce Elevated IL-1β Secretion: A Primary Human Monocyte Model.

Callaway JB, Smith SA, Widman DG, McKinnon KP, Scholle F, Sempowski GD, Dittmer DP, Crowe JE Jr, de Silva AM, Ting JP.

PLoS One. 2015 Aug 24;10(8):e0136708. doi: 10.1371/journal.pone.0136708. eCollection 2015.


Spleen Tyrosine Kinase (Syk) Mediates IL-1β Induction by Primary Human Monocytes during Antibody-enhanced Dengue Virus Infection.

Callaway JB, Smith SA, McKinnon KP, de Silva AM, Crowe JE Jr, Ting JP.

J Biol Chem. 2015 Jul 10;290(28):17306-20. doi: 10.1074/jbc.M115.664136. Epub 2015 Jun 1.


Analysis of human innate immune responses to PRINT fabricated nanoparticles with cross validation using a humanized mouse model.

Robbins GR, Roberts RA, Guo H, Reuter K, Shen T, Sempowski GD, McKinnon KP, Su L, DeSimone JM, Ting JP.

Nanomedicine. 2015 Apr;11(3):589-99. doi: 10.1016/j.nano.2014.11.010. Epub 2015 Jan 14.


Peptide/MHC tetramer-based sorting of CD8⁺ T cells to a leukemia antigen yields clonotypes drawn nonspecifically from an underlying restricted repertoire.

Hunsucker SA, McGary CS, Vincent BG, Enyenihi AA, Waugh JP, McKinnon KP, Bixby LM, Ropp PA, Coghill JM, Wood WA, Gabriel DA, Sarantopoulos S, Shea TC, Serody JS, Alatrash G, Rodriguez-Cruz T, Lizée G, Buntzman AS, Frelinger JA, Glish GL, Armistead PM.

Cancer Immunol Res. 2015 Mar;3(3):228-35. doi: 10.1158/2326-6066.CIR-14-0001. Epub 2015 Jan 9.


CC chemokine receptor 8 potentiates donor Treg survival and is critical for the prevention of murine graft-versus-host disease.

Coghill JM, Fowler KA, West ML, Fulton LM, van Deventer H, McKinnon KP, Vincent BG, Lin K, Panoskaltsis-Mortari A, Cook DN, Blazar BR, Serody JS.

Blood. 2013 Aug 1;122(5):825-36. doi: 10.1182/blood-2012-06-435735. Epub 2013 Jun 24.


Neisseria gonorrhoeae suppresses dendritic cell-induced, antigen-dependent CD4 T cell proliferation.

Zhu W, Ventevogel MS, Knilans KJ, Anderson JE, Oldach LM, McKinnon KP, Hobbs MM, Sempowski GD, Duncan JA.

PLoS One. 2012;7(7):e41260. doi: 10.1371/journal.pone.0041260. Epub 2012 Jul 23.


The SecA2 secretion factor of Mycobacterium tuberculosis promotes growth in macrophages and inhibits the host immune response.

Kurtz S, McKinnon KP, Runge MS, Ting JP, Braunstein M.

Infect Immun. 2006 Dec;74(12):6855-64. Epub 2006 Oct 9.


Cutting edge: rho activation and actin polarization are dependent on plexin-A1 in dendritic cells.

Eun SY, O'Connor BP, Wong AW, van Deventer HW, Taxman DJ, Reed W, Li P, Blum JS, McKinnon KP, Ting JP.

J Immunol. 2006 Oct 1;177(7):4271-5.


Combined donor specific transfusion and anti-CD154 therapy achieves airway allograft tolerance.

Chalermskulrat W, McKinnon KP, Brickey WJ, Neuringer IP, Park RC, Sterka DG, Long BR, McNeillie P, Noelle RJ, Ting JP, Aris RM.

Thorax. 2006 Jan;61(1):61-7. Epub 2005 Oct 27.


A novel viral system for generating antigen-specific T cells.

Moran TP, Collier M, McKinnon KP, Davis NL, Johnston RE, Serody JS.

J Immunol. 2005 Sep 1;175(5):3431-8.


Critical role for CCR5 in the function of donor CD4+CD25+ regulatory T cells during acute graft-versus-host disease.

Wysocki CA, Jiang Q, Panoskaltsis-Mortari A, Taylor PA, McKinnon KP, Su L, Blazar BR, Serody JS.

Blood. 2005 Nov 1;106(9):3300-7. Epub 2005 Jul 7.


Dendritic cells can be rapidly expanded ex vivo and safely administered in patients with metastatic breast cancer.

Dees EC, McKinnon KP, Kuhns JJ, Chwastiak KA, Sparks S, Myers M, Collins EJ, Frelinger JA, Van Deventer H, Collichio F, Carey LA, Brecher ME, Graham M, Earp HS, Serody JS.

Cancer Immunol Immunother. 2004 Sep;53(9):777-85. Epub 2004 Jun 8.


CIITA-regulated plexin-A1 affects T-cell-dendritic cell interactions.

Wong AW, Brickey WJ, Taxman DJ, van Deventer HW, Reed W, Gao JX, Zheng P, Liu Y, Li P, Blum JS, McKinnon KP, Ting JP.

Nat Immunol. 2003 Sep;4(9):891-8. Epub 2003 Aug 10.


Regulation and specificity of MHC2TA promoter usage in human primary T lymphocytes and cell line.

Wong AW, Ghosh N, McKinnon KP, Reed W, Piskurich JF, Wright KL, Ting JP.

J Immunol. 2002 Sep 15;169(6):3112-9.


Transfection of macrophage inflammatory protein 1 alpha into B16 F10 melanoma cells inhibits growth of pulmonary metastases but not subcutaneous tumors.

van Deventer HW, Serody JS, McKinnon KP, Clements C, Brickey WJ, Ting JP.

J Immunol. 2002 Aug 1;169(3):1634-9.


Dendritic cells improve the generation of Epstein-Barr virus-specific cytotoxic T lymphocytes for the treatment of posttransplantation lymphoma.

Wheatley GH 3rd, McKinnon KP, Iacobucci M, Mahon S, Gelber C, Lyerly HK.

Surgery. 1998 Aug;124(2):171-6.


[In vitro exposure of a human bronchial epithelial cell line with nitrogen dioxide induces enhanced transcription and liberation of pro-inflammatory cytokines].

Kienast K, McKinnon KP, Madden M, Carter JD, Reed W, Becker S, Devlin RB.

Pneumologie. 1995 Dec;49(12):695-9. German.


Tight junctions and mucin mRNA in BEAS-2B cells.

Noah TL, Yankaskas JR, Carson JL, Gambling TM, Cazares LH, McKinnon KP, Devlin RB.

In Vitro Cell Dev Biol Anim. 1995 Nov;31(10):738-40. No abstract available.


Ozone-induced release of cytokines and fibronectin by alveolar macrophages and airway epithelial cells.

Devlin RB, McKinnon KP, Noah T, Becker S, Koren HS.

Am J Physiol. 1994 Jun;266(6 Pt 1):L612-9.


In vitro ozone exposure increases release of arachidonic acid products from a human bronchial epithelial cell line.

McKinnon KP, Madden MC, Noah TL, Devlin RB.

Toxicol Appl Pharmacol. 1993 Feb;118(2):215-23.


The response of a human bronchial epithelial cell line to histamine: intracellular calcium changes and extracellular release of inflammatory mediators.

Noah TL, Paradiso AM, Madden MC, McKinnon KP, Devlin RB.

Am J Respir Cell Mol Biol. 1991 Nov;5(5):484-92.


Lipopolysaccharide exposure during purification of human monocytes by adherence increases their recovery and cytolytic activity.

Chen AR, Whitaker FS, McKinnon KP, Koren HS.

Cell Immunol. 1986 Nov;103(1):120-32.


Cytolysis of actinomycin D-treated target cells by cell-free supernatants from human monocytes.

McKinnon KP, Chen AR, Argov S, Lane BC, Koren HS.

Immunobiology. 1986 Mar;171(1-2):27-44.


Suppression of mitogen- and tumor-cell-induced lymphocyte stimulation by tumor-associated fetal antigens.

Evans DL, Frank MK, McKinnon KP, Cerrone MC.

Cell Immunol. 1981 Jan 1;57(1):155-74. No abstract available.


Immunological characterizations of tumor-associated fetal antigens.

Evans DL, Frank MK, McKinnon KP, Cerrone M.

Cancer Res. 1979 Jun;39(6 Pt 1):2016-25. No abstract available.

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