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Items: 24


Antigen Availability Shapes T Cell Differentiation and Function during Tuberculosis.

Moguche AO, Musvosvi M, Penn-Nicholson A, Plumlee CR, Mearns H, Geldenhuys H, Smit E, Abrahams D, Rozot V, Dintwe O, Hoff ST, Kromann I, Ruhwald M, Bang P, Larson RP, Shafiani S, Ma S, Sherman DR, Sette A, Lindestam Arlehamn CS, McKinney DM, Maecker H, Hanekom WA, Hatherill M, Andersen P, Scriba TJ, Urdahl KB.

Cell Host Microbe. 2017 Jun 14;21(6):695-706.e5. doi: 10.1016/j.chom.2017.05.012.


A Quantitative Analysis of Complexity of Human Pathogen-Specific CD4 T Cell Responses in Healthy M. tuberculosis Infected South Africans.

Lindestam Arlehamn CS, McKinney DM, Carpenter C, Paul S, Rozot V, Makgotlho E, Gregg Y, van Rooyen M, Ernst JD, Hatherill M, Hanekom WA, Peters B, Scriba TJ, Sette A.

PLoS Pathog. 2016 Jul 13;12(7):e1005760. doi: 10.1371/journal.ppat.1005760. eCollection 2016 Jul.


T-cell epitope conservation across allergen species is a major determinant of immunogenicity.

Westernberg L, Schulten V, Greenbaum JA, Natali S, Tripple V, McKinney DM, Frazier A, Hofer H, Wallner M, Sallusto F, Sette A, Peters B.

J Allergy Clin Immunol. 2016 Aug;138(2):571-578.e7. doi: 10.1016/j.jaci.2015.11.034. Epub 2016 Feb 13.


Development and validation of a sample sparing strategy for HLA typing utilizing next generation sequencing.

McKinney DM, Fu Z, Le L, Greenbaum JA, Peters B, Sette A.

Hum Immunol. 2015 Dec;76(12):917-22. doi: 10.1016/j.humimm.2015.04.007. Epub 2015 May 28.


A population response analysis approach to assign class II HLA-epitope restrictions.

Paul S, Dillon MBC, Arlehamn CSL, Huang H, Davis MM, McKinney DM, Scriba TJ, Sidney J, Peters B, Sette A.

J Immunol. 2015 Jun 15;194(12):6164-6176. doi: 10.4049/jimmunol.1403074. Epub 2015 May 6.


Development and validation of a broad scheme for prediction of HLA class II restricted T cell epitopes.

Paul S, Lindestam Arlehamn CS, Scriba TJ, Dillon MB, Oseroff C, Hinz D, McKinney DM, Carrasco Pro S, Sidney J, Peters B, Sette A.

J Immunol Methods. 2015 Jul;422:28-34. doi: 10.1016/j.jim.2015.03.022. Epub 2015 Apr 7.


Asymptomatic HLA-A*02:01-restricted epitopes from herpes simplex virus glycoprotein B preferentially recall polyfunctional CD8+ T cells from seropositive asymptomatic individuals and protect HLA transgenic mice against ocular herpes.

Dervillez X, Qureshi H, Chentoufi AA, Khan AA, Kritzer E, Yu DC, Diaz OR, Gottimukkala C, Kalantari M, Villacres MC, Scarfone VM, McKinney DM, Sidney J, Sette A, Nesburn AB, Wechsler SL, BenMohamed L.

J Immunol. 2013 Nov 15;191(10):5124-38. doi: 10.4049/jimmunol.1301415. Epub 2013 Oct 7.


Previously undescribed grass pollen antigens are the major inducers of T helper 2 cytokine-producing T cells in allergic individuals.

Schulten V, Greenbaum JA, Hauser M, McKinney DM, Sidney J, Kolla R, Lindestam Arlehamn CS, Oseroff C, Alam R, Broide DH, Ferreira F, Grey HM, Sette A, Peters B.

Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3459-64. doi: 10.1073/pnas.1300512110. Epub 2013 Feb 11. Erratum in: Proc Natl Acad Sci U S A. 2013 Mar 26;110(13):5269. Ferreira-Briza, Fatima [corrected to Ferreira, Fatima]. Proc Natl Acad Sci U S A. 2013 May 21;110(21):8750.


A strategy to determine HLA class II restriction broadly covering the DR, DP, and DQ allelic variants most commonly expressed in the general population.

McKinney DM, Southwood S, Hinz D, Oseroff C, Arlehamn CS, Schulten V, Taplitz R, Broide D, Hanekom WA, Scriba TJ, Wood R, Alam R, Peters B, Sidney J, Sette A.

Immunogenetics. 2013 May;65(5):357-70. doi: 10.1007/s00251-013-0684-y. Epub 2013 Feb 8.


Memory T cells in latent Mycobacterium tuberculosis infection are directed against three antigenic islands and largely contained in a CXCR3+CCR6+ Th1 subset.

Lindestam Arlehamn CS, Gerasimova A, Mele F, Henderson R, Swann J, Greenbaum JA, Kim Y, Sidney J, James EA, Taplitz R, McKinney DM, Kwok WW, Grey H, Sallusto F, Peters B, Sette A.

PLoS Pathog. 2013 Jan;9(1):e1003130. doi: 10.1371/journal.ppat.1003130. Epub 2013 Jan 24.


T cell responses to known allergen proteins are differently polarized and account for a variable fraction of total response to allergen extracts.

Oseroff C, Sidney J, Vita R, Tripple V, McKinney DM, Southwood S, Brodie TM, Sallusto F, Grey H, Alam R, Broide D, Greenbaum JA, Kolla R, Peters B, Sette A.

J Immunol. 2012 Aug 15;189(4):1800-11. doi: 10.4049/jimmunol.1200850. Epub 2012 Jul 11.


Dissecting mechanisms of immunodominance to the common tuberculosis antigens ESAT-6, CFP10, Rv2031c (hspX), Rv2654c (TB7.7), and Rv1038c (EsxJ).

Arlehamn CS, Sidney J, Henderson R, Greenbaum JA, James EA, Moutaftsi M, Coler R, McKinney DM, Park D, Taplitz R, Kwok WW, Grey H, Peters B, Sette A.

J Immunol. 2012 May 15;188(10):5020-31. doi: 10.4049/jimmunol.1103556. Epub 2012 Apr 13.


Molecular determinants of T cell epitope recognition to the common Timothy grass allergen.

Oseroff C, Sidney J, Kotturi MF, Kolla R, Alam R, Broide DH, Wasserman SI, Weiskopf D, McKinney DM, Chung JL, Petersen A, Grey H, Peters B, Sette A.

J Immunol. 2010 Jul 15;185(2):943-55. doi: 10.4049/jimmunol.1000405. Epub 2010 Jun 16.


A novel HIV T helper epitope-based vaccine elicits cytokine-secreting HIV-specific CD4+ T cells in a Phase I clinical trial in HIV-uninfected adults.

Jin X, Newman MJ, De-Rosa S, Cooper C, Thomas E, Keefer M, Fuchs J, Blattner W, Livingston BD, McKinney DM, Noonan E, Decamp A, Defawe OD, Wecker M; NIAID HIV Vaccine Trials Network.

Vaccine. 2009 Nov 23;27(50):7080-6. doi: 10.1016/j.vaccine.2009.09.060. Epub 2009 Sep 26.


Recognition of variant HIV-1 epitopes from diverse viral subtypes by vaccine-induced CTL.

McKinney DM, Skvoretz R, Livingston BD, Wilson CC, Anders M, Chesnut RW, Sette A, Essex M, Novitsky V, Newman MJ.

J Immunol. 2004 Aug 1;173(3):1941-50.


T-lymphocyte epitope identification and their use in vaccine development for HIV-1.

Newman MJ, Livingston B, McKinney DM, Chesnut RW, Sette A.

Front Biosci. 2002 Jun 1;7:d1503-15. Review.


Identification of five different Patr class I molecules that bind HLA supertype peptides and definition of their peptide binding motifs.

McKinney DM, Erickson AL, Walker CM, Thimme R, Chisari FV, Sidney J, Sette A.

J Immunol. 2000 Oct 15;165(8):4414-22.


The antiviral activity of HIV-specific CD8+ CTL clones is limited by elimination due to encounter with HIV-infected targets.

McKinney DM, Lewinsohn DA, Riddell SR, Greenberg PD, Mosier DE.

J Immunol. 1999 Jul 15;163(2):861-7.


Single Dd amino acid substitutions in the H-2Ld molecule identify antibody epitopes.

McKinney DM, Chen P, McMillan M.

Immunogenetics. 1994;39(6):440-3. No abstract available.


Molecular analysis of H-2 class I molecules expressed on the UV-induced tumour 1591.

McKinney DM, McMillan M.

J Immunogenet. 1990 Jun;17(3):177-87.


Molecular characterization of the C3HfB/HeN H-2Kkm2 mutation. Implications for the molecular basis of alloreactivity.

Vogel JM, Davis AC, McKinney DM, McMillan M, Martin WJ, Goodenow RS.

J Exp Med. 1988 Nov 1;168(5):1781-800.

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