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Items: 42


Identification and Characterization of Unique Neutralizing Antibodies to Mouse EGF Receptor.

Jae Huh W, Niitsu H, Carney B, McKinley ET, Houghton JL, Coffey RJ.

Gastroenterology. 2020 Apr;158(5):1500-1502. doi: 10.1053/j.gastro.2019.12.017. Epub 2019 Dec 19. No abstract available.


Magnetic resonance imaging of mean cell size in human breast tumors.

Xu J, Jiang X, Li H, Arlinghaus LR, McKinley ET, Devan SP, Hardy BM, Xie J, Kang H, Chakravarthy AB, Gore JC.

Magn Reson Med. 2020 Jun;83(6):2002-2014. doi: 10.1002/mrm.28056. Epub 2019 Nov 25.


In vivo magnetic resonance imaging of treatment-induced apoptosis.

Jiang X, McKinley ET, Xie J, Li H, Xu J, Gore JC.

Sci Rep. 2019 Jul 2;9(1):9540. doi: 10.1038/s41598-019-45864-y.


Transfer of Functional Cargo in Exomeres.

Zhang Q, Higginbotham JN, Jeppesen DK, Yang YP, Li W, McKinley ET, Graves-Deal R, Ping J, Britain CM, Dorsett KA, Hartman CL, Ford DA, Allen RM, Vickers KC, Liu Q, Franklin JL, Bellis SL, Coffey RJ.

Cell Rep. 2019 Apr 16;27(3):940-954.e6. doi: 10.1016/j.celrep.2019.01.009. Epub 2019 Apr 4.


Mutant KRAS Exosomes Alter the Metabolic State of Recipient Colonic Epithelial Cells.

Zhang Q, Jeppesen DK, Higginbotham JN, Demory Beckler M, Poulin EJ, Walsh AJ, Skala MC, McKinley ET, Manning HC, Hight MR, Schulte ML, Watt KR, Ayers GD, Wolf MM, Andrejeva G, Rathmell JC, Franklin JL, Coffey RJ.

Cell Mol Gastroenterol Hepatol. 2018 Jan 31;5(4):627-629.e6. doi: 10.1016/j.jcmgh.2018.01.013. eCollection 2018. No abstract available.


Interpreting heterogeneity in intestinal tuft cell structure and function.

Banerjee A, McKinley ET, von Moltke J, Coffey RJ, Lau KS.

J Clin Invest. 2018 May 1;128(5):1711-1719. doi: 10.1172/JCI120330. Epub 2018 May 1. Review.


Single-Cell Computational Strategies for Lineage Reconstruction in Tissue Systems.

Herring CA, Chen B, McKinley ET, Lau KS.

Cell Mol Gastroenterol Hepatol. 2018 Feb 13;5(4):539-548. doi: 10.1016/j.jcmgh.2018.01.023. eCollection 2018. Review.


Unsupervised Trajectory Analysis of Single-Cell RNA-Seq and Imaging Data Reveals Alternative Tuft Cell Origins in the Gut.

Herring CA, Banerjee A, McKinley ET, Simmons AJ, Ping J, Roland JT, Franklin JL, Liu Q, Gerdes MJ, Coffey RJ, Lau KS.

Cell Syst. 2018 Jan 24;6(1):37-51.e9. doi: 10.1016/j.cels.2017.10.012. Epub 2017 Nov 15.


Optimized multiplex immunofluorescence single-cell analysis reveals tuft cell heterogeneity.

McKinley ET, Sui Y, Al-Kofahi Y, Millis BA, Tyska MJ, Roland JT, Santamaria-Pang A, Ohland CL, Jobin C, Franklin JL, Lau KS, Gerdes MJ, Coffey RJ.

JCI Insight. 2017 Jun 2;2(11). pii: 93487. doi: 10.1172/jci.insight.93487. eCollection 2017 Jun 2.


Impaired coordination between signaling pathways is revealed in human colorectal cancer using single-cell mass cytometry of archival tissue blocks.

Simmons AJ, Scurrah CR, McKinley ET, Herring CA, Irish JM, Washington MK, Coffey RJ, Lau KS.

Sci Signal. 2016 Oct 11;9(449):rs11.


Cytometry-based single-cell analysis of intact epithelial signaling reveals MAPK activation divergent from TNF-α-induced apoptosis in vivo.

Simmons AJ, Banerjee A, McKinley ET, Scurrah CR, Herring CA, Gewin LS, Masuzaki R, Karp SJ, Franklin JL, Gerdes MJ, Irish JM, Coffey RJ, Lau KS.

Mol Syst Biol. 2016 Aug 29;12(8):881. doi: 10.15252/msb.20167270. No abstract available.


In vivo imaging of cancer cell size and cellularity using temporal diffusion spectroscopy.

Jiang X, Li H, Xie J, McKinley ET, Zhao P, Gore JC, Xu J.

Magn Reson Med. 2017 Jul;78(1):156-164. doi: 10.1002/mrm.26356. Epub 2016 Aug 6.


Cytometry-based single-cell analysis of intact epithelial signaling reveals MAPK activation divergent from TNF-α-induced apoptosis in vivo.

Simmons AJ, Banerjee A, McKinley ET, Scurrah CR, Herring CA, Gewin LS, Masuzaki R, Karp SJ, Franklin JL, Gerdes MJ, Irish JM, Coffey RJ, Lau KS.

Mol Syst Biol. 2015 Oct 30;11(10):835. doi: 10.15252/msb.20156282. Erratum in: Mol Syst Biol. 2016 Aug 29;12(8):881.


Preclinical TSPO Ligand PET to Visualize Human Glioma Xenotransplants: A Preliminary Study.

Buck JR, McKinley ET, Fu A, Abel TW, Thompson RC, Chambless L, Watchmaker JM, Harty JP, Cooper MK, Manning HC.

PLoS One. 2015 Oct 30;10(10):e0141659. doi: 10.1371/journal.pone.0141659. eCollection 2015.


[(18)F]-FLT PET to predict early response to neoadjuvant therapy in KRAS wild-type rectal cancer: a pilot study.

McKinley ET, Watchmaker JM, Chakravarthy AB, Meyerhardt JA, Engelman JA, Walker RC, Washington MK, Coffey RJ, Manning HC.

Ann Nucl Med. 2015 Jul;29(6):535-42. doi: 10.1007/s12149-015-0974-6. Epub 2015 Apr 22.


High-yielding, automated production of 3'-deoxy-3'-[(18)F]fluorothymidine using a modified Bioscan Coincidence FDG reaction module.

Cheung YY, Nickels ML, McKinley ET, Buck JR, Manning HC.

Appl Radiat Isot. 2015 Mar;97:47-51. doi: 10.1016/j.apradiso.2014.11.011. Epub 2014 Dec 15.


3'-Deoxy-3'-[18F]-Fluorothymidine PET imaging reflects PI3K-mTOR-mediated pro-survival response to targeted therapy in colorectal cancer.

McKinley ET, Zhao P, Coffey RJ, Washington MK, Manning HC.

PLoS One. 2014 Sep 23;9(9):e108193. doi: 10.1371/journal.pone.0108193. eCollection 2014.


Inducible loss of one Apc allele in Lrig1-expressing progenitor cells results in multiple distal colonic tumors with features of familial adenomatous polyposis.

Powell AE, Vlacich G, Zhao ZY, McKinley ET, Washington MK, Manning HC, Coffey RJ.

Am J Physiol Gastrointest Liver Physiol. 2014 Jul 1;307(1):G16-23. doi: 10.1152/ajpgi.00358.2013. Epub 2014 May 15.


Global phosphotyrosine proteomics identifies PKCδ as a marker of responsiveness to Src inhibition in colorectal cancer.

McKinley ET, Liu H, McDonald WH, Luo W, Zhao P, Coffey RJ, Hanks SK, Manning HC.

PLoS One. 2013 Nov 8;8(11):e80207. doi: 10.1371/journal.pone.0080207. eCollection 2013.


Limits of [18F]-FLT PET as a biomarker of proliferation in oncology.

McKinley ET, Ayers GD, Smith RA, Saleh SA, Zhao P, Washington MK, Coffey RJ, Manning HC.

PLoS One. 2013;8(3):e58938. doi: 10.1371/journal.pone.0058938. Epub 2013 Mar 15.


Synthesis and structure-activity relationships of 5,6,7-substituted pyrazolopyrimidines: discovery of a novel TSPO PET ligand for cancer imaging.

Tang D, McKinley ET, Hight MR, Uddin MI, Harp JM, Fu A, Nickels ML, Buck JR, Manning HC.

J Med Chem. 2013 Apr 25;56(8):3429-33. doi: 10.1021/jm4001874. Epub 2013 Apr 3.


Optimal specimen collection and transport methods for the detection of avian influenza virus and Newcastle disease virus.

Spackman E, Pedersen JC, McKinley ET, Gelb J Jr.

BMC Vet Res. 2013 Feb 22;9:35. doi: 10.1186/1746-6148-9-35.


3'-Deoxy-3'-18F-fluorothymidine PET predicts response to (V600E)BRAF-targeted therapy in preclinical models of colorectal cancer.

McKinley ET, Smith RA, Zhao P, Fu A, Saleh SA, Uddin MI, Washington MK, Coffey RJ, Manning HC.

J Nucl Med. 2013 Mar;54(3):424-30. doi: 10.2967/jnumed.112.108456. Epub 2013 Jan 22.


[18F]FLT-PET to predict pharmacodynamic and clinical response to cetuximab therapy in Ménétrier's disease.

McKinley ET, Smith RA, Tanksley JP, Washington MK, Walker R, Coffey RJ, Manning HC.

Ann Nucl Med. 2012 Nov;26(9):757-63. doi: 10.1007/s12149-012-0636-x. Epub 2012 Jul 22.


Quantitative preclinical imaging of TSPO expression in glioma using N,N-diethyl-2-(2-(4-(2-18F-fluoroethoxy)phenyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidin-3-yl)acetamide.

Tang D, Hight MR, McKinley ET, Fu A, Buck JR, Smith RA, Tantawy MN, Peterson TE, Colvin DC, Ansari MS, Nickels M, Manning HC.

J Nucl Med. 2012 Feb;53(2):287-94. doi: 10.2967/jnumed.111.095653. Epub 2012 Jan 17.


Changes in nonstructural protein 3 are associated with attenuation in avian coronavirus infectious bronchitis virus.

Phillips JE, Jackwood MW, McKinley ET, Thor SW, Hilt DA, Acevedol ND, Williams SM, Kissinger JC, Paterson AH, Robertson JS, Lemke C.

Virus Genes. 2012 Feb;44(1):63-74. doi: 10.1007/s11262-011-0668-7. Epub 2011 Sep 10.


H7 avian influenza virus vaccines protect chickens against challenge with antigenically diverse isolates.

Abbas MA, Spackman E, Fouchier R, Smith D, Ahmed Z, Siddique N, Sarmento L, Naeem K, McKinley ET, Hameed A, Rehmani S, Swayne DE.

Vaccine. 2011 Oct 6;29(43):7424-9. doi: 10.1016/j.vaccine.2011.07.064. Epub 2011 Jul 29.


Attenuated live vaccine usage affects accurate measures of virus diversity and mutation rates in avian coronavirus infectious bronchitis virus.

McKinley ET, Jackwood MW, Hilt DA, Kissinger JC, Robertson JS, Lemke C, Paterson AH.

Virus Res. 2011 Jun;158(1-2):225-34. doi: 10.1016/j.virusres.2011.04.006. Epub 2011 Apr 22.


Multispectral fluorescence imaging to assess pH in biological specimens.

Hight MR, Nolting DD, McKinley ET, Lander AD, Wyatt SK, Gonyea M, Zhao P, Manning HC.

J Biomed Opt. 2011 Jan-Feb;16(1):016007. doi: 10.1117/1.3533264.


18FDG-PET predicts pharmacodynamic response to OSI-906, a dual IGF-1R/IR inhibitor, in preclinical mouse models of lung cancer.

McKinley ET, Bugaj JE, Zhao P, Guleryuz S, Mantis C, Gokhale PC, Wild R, Manning HC.

Clin Cancer Res. 2011 May 15;17(10):3332-40. doi: 10.1158/1078-0432.CCR-10-2274. Epub 2011 Jan 21.


Quantitative, preclinical PET of translocator protein expression in glioma using 18F-N-fluoroacetyl-N-(2,5-dimethoxybenzyl)-2-phenoxyaniline.

Buck JR, McKinley ET, Hight MR, Fu A, Tang D, Smith RA, Tantawy MN, Peterson TE, Colvin D, Ansari MS, Baldwin RM, Zhao P, Guleryuz S, Manning HC.

J Nucl Med. 2011 Jan;52(1):107-14. doi: 10.2967/jnumed.110.081703. Epub 2010 Dec 13.


The pathogenesis of low pathogenicity H7 avian influenza viruses in chickens, ducks and turkeys.

Spackman E, Gelb J Jr, Preskenis LA, Ladman BS, Pope CR, Pantin-Jackwood MJ, McKinley ET.

Virol J. 2010 Nov 19;7:331. doi: 10.1186/1743-422X-7-331.


The pathogenesis of H3N8 canine influenza virus in chickens, turkeys and ducks.

McKinley ET, Spackman E, Pantin-Jackwood MJ.

Influenza Other Respir Viruses. 2010 Nov;4(6):353-6. doi: 10.1111/j.1750-2659.2010.00165.x. Epub 2010 Aug 24.


Volume of preclinical xenograft tumors is more accurately assessed by ultrasound imaging than manual caliper measurements.

Ayers GD, McKinley ET, Zhao P, Fritz JM, Metry RE, Deal BC, Adlerz KM, Coffey RJ, Manning HC.

J Ultrasound Med. 2010 Jun;29(6):891-901.


Emergence of a group 3 coronavirus through recombination.

Jackwood MW, Boynton TO, Hilt DA, McKinley ET, Kissinger JC, Paterson AH, Robertson J, Lemke C, McCall AW, Williams SM, Jackwood JW, Byrd LA.

Virology. 2010 Mar 1;398(1):98-108. doi: 10.1016/j.virol.2009.11.044.


Infectious bronchitis virus field vaccination coverage and persistence of Arkansas-type viruses in commercial broilers.

Jackwood MW, Hilt DA, McCall AW, Polizzi CN, McKinley ET, Williams SM.

Avian Dis. 2009 Jun;53(2):175-83.


Imaging biomarkers predict response to anti-HER2 (ErbB2) therapy in preclinical models of breast cancer.

Shah C, Miller TW, Wyatt SK, McKinley ET, Olivares MG, Sanchez V, Nolting DD, Buck JR, Zhao P, Ansari MS, Baldwin RM, Gore JC, Schiff R, Arteaga CL, Manning HC.

Clin Cancer Res. 2009 Jul 15;15(14):4712-21. doi: 10.1158/1078-0432.CCR-08-2635. Epub 2009 Jul 7.


Molecular imaging of therapeutic response to epidermal growth factor receptor blockade in colorectal cancer.

Manning HC, Merchant NB, Foutch AC, Virostko JM, Wyatt SK, Shah C, McKinley ET, Xie J, Mutic NJ, Washington MK, LaFleur B, Tantawy MN, Peterson TE, Ansari MS, Baldwin RM, Rothenberg ML, Bornhop DJ, Gore JC, Coffey RJ.

Clin Cancer Res. 2008 Nov 15;14(22):7413-22. doi: 10.1158/1078-0432.CCR-08-0239.


Avian coronavirus infectious bronchitis attenuated live vaccines undergo selection of subpopulations and mutations following vaccination.

McKinley ET, Hilt DA, Jackwood MW.

Vaccine. 2008 Mar 4;26(10):1274-84. doi: 10.1016/j.vaccine.2008.01.006. Epub 2008 Jan 18.


Neuroprotection of MPTP-induced toxicity in zebrafish dopaminergic neurons.

McKinley ET, Baranowski TC, Blavo DO, Cato C, Doan TN, Rubinstein AL.

Brain Res Mol Brain Res. 2005 Nov 30;141(2):128-37. Epub 2005 Oct 4.


Inflammatory myofibroblastic tumor of the gastroesophageal junction in childhood.

SantaCruz KS, McKinley ET, Powell RD Jr, Hermreck AS, Sonnino RE.

Pediatr Pathol Mol Med. 2002 Jan-Feb;21(1):49-56.


Digital constriction bands in pseudoainhum: morphological radiographic, and histological analysis.

Pickus EJ, Lionelli GT, McKinley ET, Lawrence WT, Witt PD.

Ann Plast Surg. 2001 Aug;47(2):194-8.


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