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Items: 1 to 50 of 80

1.

Integration of Canonical and Noncanonical Pathways in TLR4 Signaling: Complex Regulation of the Wound Repair Program.

McKeown-Longo PJ, Higgins PJ.

Adv Wound Care (New Rochelle). 2017 Oct 1;6(10):320-329. doi: 10.1089/wound.2017.0736. Review.

2.

TLR4 Ligands Selectively Synergize to Induce Expression of IL-8.

Valenty LM, Longo CM, Horzempa C, Ambesi A, McKeown-Longo PJ.

Adv Wound Care (New Rochelle). 2017 Oct 1;6(10):309-319. doi: 10.1089/wound.2017.0735.

3.

Integrin α4β1 and TLR4 Cooperate to Induce Fibrotic Gene Expression in Response to Fibronectin's EDA Domain.

Kelsh-Lasher RM, Ambesi A, Bertram C, McKeown-Longo PJ.

J Invest Dermatol. 2017 Dec;137(12):2505-2512. doi: 10.1016/j.jid.2017.08.005. Epub 2017 Aug 24.

4.
5.

EDA Fibronectin in Keloids Create a Vicious Cycle of Fibrotic Tumor Formation.

Kelsh RM, McKeown-Longo PJ, Clark RAF.

J Invest Dermatol. 2015 Jul;135(7):1714-1718. doi: 10.1038/jid.2015.155.

6.

Role of EGFR expression levels in the regulation of integrin function by EGF.

Vial D, McKeown-Longo PJ.

Mol Carcinog. 2016 Jun;55(6):1118-23. doi: 10.1002/mc.22346. Epub 2015 Jun 4.

7.

Cryptic activity within the Type III1 domain of fibronectin regulates tissue inflammation and angiogenesis.

Cho C, Kelsh-Lasher R, Ambesi A, McKeown-Longo PJ.

Curr Top Pept Protein Res. 2015;16:37-47.

8.

The α4β1 integrin and the EDA domain of fibronectin regulate a profibrotic phenotype in dermal fibroblasts.

Shinde AV, Kelsh R, Peters JH, Sekiguchi K, Van De Water L, McKeown-Longo PJ.

Matrix Biol. 2015 Jan;41:26-35. doi: 10.1016/j.matbio.2014.11.004. Epub 2014 Nov 26.

9.

Regulation of the innate immune response by fibronectin: synergism between the III-1 and EDA domains.

Kelsh R, You R, Horzempa C, Zheng M, McKeown-Longo PJ.

PLoS One. 2014 Jul 22;9(7):e102974. doi: 10.1371/journal.pone.0102974. eCollection 2014.

10.

Conformational remodeling of the fibronectin matrix selectively regulates VEGF signaling.

Ambesi A, McKeown-Longo PJ.

J Cell Sci. 2014 Sep 1;127(Pt 17):3805-16. doi: 10.1242/jcs.150458. Epub 2014 Jun 30.

11.
12.

Epidermal growth factor (EGF) regulates α5β1 integrin activation state in human cancer cell lines through the p90RSK-dependent phosphorylation of filamin A.

Vial D, McKeown-Longo PJ.

J Biol Chem. 2012 Nov 23;287(48):40371-80. doi: 10.1074/jbc.M112.389577. Epub 2012 Sep 24.

13.

The First Type III Domain of Fibronectin is Associated with the Expression of Cytokines within the Lung Tumor Microenvironment.

Zheng M, Jones DM, Horzempa C, Prasad A, McKeown-Longo PJ.

J Cancer. 2011;2:478-83. Epub 2011 Sep 27.

14.

The first type III repeat in fibronectin activates an inflammatory pathway in dermal fibroblasts.

You R, Zheng M, McKeown-Longo PJ.

J Biol Chem. 2010 Nov 19;285(47):36255-9. doi: 10.1074/jbc.C110.176990. Epub 2010 Oct 5.

15.

Regulation of p38 MAP kinase by anastellin is independent of anastellin's effect on matrix fibronectin.

You R, Klein RM, Zheng M, McKeown-Longo PJ.

Matrix Biol. 2009 Mar;28(2):101-9. doi: 10.1016/j.matbio.2009.01.003. Epub 2009 Feb 4.

16.

Anastellin, the angiostatic fibronectin peptide, is a selective inhibitor of lysophospholipid signaling.

Ambesi A, McKeown-Longo PJ.

Mol Cancer Res. 2009 Feb;7(2):255-65. doi: 10.1158/1541-7786.MCR-08-0195. Epub 2009 Feb 10.

17.

Endostatin and anastellin inhibit distinct aspects of the angiogenic process.

Neskey DM, Ambesi A, Pumiglia KM, McKeown-Longo PJ.

J Exp Clin Cancer Res. 2008 Nov 4;27:61. doi: 10.1186/1756-9966-27-61.

18.

A dual role for caveolin-1 in the regulation of fibronectin matrix assembly by uPAR.

Monaghan-Benson E, Mastick CC, McKeown-Longo PJ.

J Cell Sci. 2008 Nov 15;121(Pt 22):3693-703. doi: 10.1242/jcs.028423. Epub 2008 Oct 28.

19.

PAI1 stimulates assembly of the fibronectin matrix in osteosarcoma cells through crosstalk between the alphavbeta5 and alpha5beta1 integrins.

Vial D, McKeown-Longo PJ.

J Cell Sci. 2008 May 15;121(Pt 10):1661-70. doi: 10.1242/jcs.020149. Epub 2008 Apr 29.

20.

Krüppel-like factor 8 induces epithelial to mesenchymal transition and epithelial cell invasion.

Wang X, Zheng M, Liu G, Xia W, McKeown-Longo PJ, Hung MC, Zhao J.

Cancer Res. 2007 Aug 1;67(15):7184-93.

21.

The fibronectin synergy site modulates TGF-beta-dependent fibroblast contraction.

Meckmongkol TT, Harmon R, McKeown-Longo P, Van De Water L.

Biochem Biophys Res Commun. 2007 Sep 7;360(4):709-14. Epub 2007 Jul 3.

22.

The uPA receptor and the somatomedin B region of vitronectin direct the localization of uPA to focal adhesions in microvessel endothelial cells.

Salasznyk RM, Zappala M, Zheng M, Yu L, Wilkins-Port C, McKeown-Longo PJ.

Matrix Biol. 2007 Jun;26(5):359-70. Epub 2007 Feb 6.

PMID:
17344041
23.

Quantification of fibronectin matrix assembly sites using a novel ELISA assay.

Zheng M, Ambesi A, Yu L, McKeown-Longo PJ.

Matrix Biol. 2007 May;26(4):330-3. Epub 2006 Dec 29.

24.
26.

Cell adhesion regulates Ser/Thr phosphorylation and proteasomal degradation of HEF1.

Zheng M, McKeown-Longo PJ.

J Cell Sci. 2006 Jan 1;119(Pt 1):96-103. Epub 2005 Dec 13.

28.

Vitronectin's basic domain is a syndecan ligand which functions in trans to regulate vitronectin turnover.

Wilkins-Port CE, Sanderson RD, Tominna-Sebald E, McKeown-Longo PJ.

Cell Commun Adhes. 2003 Mar-Apr;10(2):85-103.

PMID:
14681059
29.

The receptor for urokinase-type plasminogen activator regulates fibronectin matrix assembly in human skin fibroblasts.

Monaghan E, Gueorguiev V, Wilkins-Port C, McKeown-Longo PJ.

J Biol Chem. 2004 Jan 9;279(2):1400-7. Epub 2003 Nov 5.

30.

Stimulation of extracellular matrix remodeling by the first type III repeat in fibronectin.

Klein RM, Zheng M, Ambesi A, Van De Water L, McKeown-Longo PJ.

J Cell Sci. 2003 Nov 15;116(Pt 22):4663-74.

31.

Regulation of HEF1 expression and phosphorylation by TGF-beta 1 and cell adhesion.

Zheng M, McKeown-Longo PJ.

J Biol Chem. 2002 Oct 18;277(42):39599-608. Epub 2002 Aug 19.

32.

TGF-beta1-induced PAI-1 gene expression requires MEK activity and cell-to-substrate adhesion.

Kutz SM, Hordines J, McKeown-Longo PJ, Higgins PJ.

J Cell Sci. 2001 Nov;114(Pt 21):3905-14.

33.

Localization of urokinase type plasminogen activator to focal adhesions requires ligation of vitronectin integrin receptors.

Wilcox-Adelman SA, Wilkins-Port CE, McKeown-Longo PJ.

Cell Adhes Commun. 2000;7(6):477-90.

PMID:
11051458
34.

Hepatic fibronectin matrix turnover in rats: involvement of the asialoglycoprotein receptor.

Rotundo RF, Vincent PA, McKeown-Longo PJ, Blumenstock FA, Saba TM.

Am J Physiol. 1999 Dec;277(6):G1189-99. doi: 10.1152/ajpgi.1999.277.6.G1189.

PMID:
10600816
35.

Lung matrix incorporation of plasma fibronectin reduces vascular permeability in postsurgical bacteremia.

Resnikoff M, Brien T, Vincent PA, Rotundo RF, Lewis E, McKeown-Longo PJ, Saba TM.

Am J Physiol. 1999 Oct;277(4):L749-59. doi: 10.1152/ajplung.1999.277.4.L749.

PMID:
10516216
36.

The amino-terminal matrix assembly domain of fibronectin stabilizes cell shape and prevents cell cycle progression.

Christopher RA, Judge SR, Vincent PA, Higgins PJ, McKeown-Longo PJ.

J Cell Sci. 1999 Oct;112 ( Pt 19):3225-35.

37.

Inhibition of fibronectin matrix assembly by the heparin-binding domain of vitronectin.

Hocking DC, Sottile J, Reho T, Fässler R, McKeown-Longo PJ.

J Biol Chem. 1999 Sep 17;274(38):27257-64.

38.

Degradation of distinct forms of multimeric vitronectin by human fibroblasts.

Wilkins-Port CE, McKeown-Longo PJ.

Biochim Biophys Acta. 1998 Sep 16;1404(3):353-66.

39.
40.

TNF-alpha-induced matrix Fn disruption and decreased endothelial integrity are independent of Fn proteolysis.

Curtis TM, Rotundo RF, Vincent PA, McKeown-Longo PJ, Saba TM.

Am J Physiol. 1998 Jul;275(1):L126-38. doi: 10.1152/ajplung.1998.275.1.L126.

PMID:
9688944
41.
42.

The alphavbeta5 integrin functions as an endocytic receptor for vitronectin.

Memmo LM, McKeown-Longo P.

J Cell Sci. 1998 Feb;111 ( Pt 4):425-33.

43.

Localization of fibronectin matrix assembly sites on fibroblasts and endothelial cells.

Christopher RA, Kowalczyk AP, McKeown-Longo PJ.

J Cell Sci. 1997 Mar;110 ( Pt 5):569-81.

44.

A novel role for the integrin-binding III-10 module in fibronectin matrix assembly.

Hocking DC, Smith RK, McKeown-Longo PJ.

J Cell Biol. 1996 Apr;133(2):431-44.

45.

Localization of urokinase to focal adhesions by human fibrosarcoma cells synthesizing recombinant vitronectin.

Wilcox SA, Reho T, Higgins PJ, Tominna-Sebald E, McKeown-Longo PJ.

Biochem Cell Biol. 1996;74(6):899-910.

PMID:
9164658
46.

Heparan sulfate proteoglycans function in the binding and degradation of vitronectin by fibroblast monolayers.

Wilkins-Port CE, McKeown-Longo PJ.

Biochem Cell Biol. 1996;74(6):887-97.

PMID:
9164657
47.

Extracellular matrix incorporation of normal and NEM-alkylated fibronectin: liver and spleen deposition.

Rebres RA, McKeown-Longo PJ, Vincent PA, Cho E, Saba TM.

Am J Physiol. 1995 Dec;269(6 Pt 1):G902-12.

PMID:
8572222
48.

Ligation of endothelial alpha v beta 3 integrin increases capillary hydraulic conductivity of rat lung.

Tsukada H, Ying X, Fu C, Ishikawa S, McKeown-Longo P, Albelda S, Bhattacharya S, Bray BA, Bhattacharya J.

Circ Res. 1995 Oct;77(4):651-9.

PMID:
7554109
49.

Alpha v beta 5 integrin receptor-mediated endocytosis of vitronectin is protein kinase C-dependent.

Panetti TS, Wilcox SA, Horzempa C, McKeown-Longo PJ.

J Biol Chem. 1995 Aug 4;270(31):18593-7.

50.

Fibronectin attenuates increased endothelial monolayer permeability after RGD peptide, anti-alpha 5 beta 1, or TNF-alpha exposure.

Curtis TM, McKeown-Longo PJ, Vincent PA, Homan SM, Wheatley EM, Saba TM.

Am J Physiol. 1995 Aug;269(2 Pt 1):L248-60.

PMID:
7544537

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