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Items: 1 to 50 of 137

1.

Anti-OX40 Antibody Directly Enhances The Function of Tumor-Reactive CD8+ T Cells and Synergizes with PI3Kβ Inhibition in PTEN Loss Melanoma.

Peng W, Williams LJ, Xu C, Melendez B, McKenzie JA, Chen Y, Jackson HL, Voo KS, Mbofung RM, Leahey SE, Wang J, Lizee G, Tawbi HA, Davies MA, Hoos A, Smothers J, Srinivasan R, Paul EM, Yanamandra N, Hwu P.

Clin Cancer Res. 2019 Aug 1. doi: 10.1158/1078-0432.CCR-19-1259. [Epub ahead of print]

PMID:
31371342
2.

Transcriptional profiling of intramembranous and endochondral ossification after fracture in mice.

Coates BA, McKenzie JA, Buettmann EG, Liu X, Gontarz PM, Zhang B, Silva MJ.

Bone. 2019 Oct;127:577-591. doi: 10.1016/j.bone.2019.07.022. Epub 2019 Jul 29.

PMID:
31369916
3.

Synthesis and Evaluation of Novel Pyrazole Ethandiamide Compounds as Inhibitors of Human THP-1 Monocytic Cell Neurotoxicity.

McKenzie JA, Barghash RF, Alsaggaf AT, Kulkarni O, Boudreau K, Menard F, Neeland EG, Klegeris A.

Cells. 2019 Jun 29;8(7). pii: E655. doi: 10.3390/cells8070655.

4.

VEGFA From Early Osteoblast Lineage Cells (Osterix+) Is Required in Mice for Fracture Healing.

Buettmann EG, McKenzie JA, Migotsky N, Sykes DA, Hu P, Yoneda S, Silva MJ.

J Bone Miner Res. 2019 Sep;34(9):1690-1706. doi: 10.1002/jbmr.3755. Epub 2019 Aug 1.

PMID:
31081125
5.

Improving warfarin therapy through implementation of a hospital-based pharmacist managed clinic in Jamaica.

Mckenzie JA, Wilson-Clarke C, Prout J, Campbell J, Douglas RD, Gossell-Williams M.

Pharm Pract (Granada). 2018 Oct-Dec;16(4):1214. doi: 10.18549/PharmPract.2018.04.1214. Epub 2018 Nov 7.

6.

Microbial community composition and dolomite formation in the hypersaline microbial mats of the Khor Al-Adaid sabkhas, Qatar.

DiLoreto ZA, Bontognali TRR, Al Disi ZA, Al-Kuwari HAS, Williford KH, Strohmenger CJ, Sadooni F, Palermo C, Rivers JM, McKenzie JA, Tuite M, Dittrich M.

Extremophiles. 2019 Mar;23(2):201-218. doi: 10.1007/s00792-018-01074-4. Epub 2019 Jan 7.

PMID:
30617527
7.

Modulation of microglial functions by methyl jasmonate.

McKenzie JA, Klegeris A.

Neural Regen Res. 2018 Jul;13(7):1290-1293. doi: 10.4103/1673-5374.235078.

8.

Activation of hedgehog signaling by systemic agonist improves fracture healing in aged mice.

McKenzie JA, Maschhoff C, Liu X, Migotsky N, Silva MJ, Gardner MJ.

J Orthop Res. 2019 Jan;37(1):51-59. doi: 10.1002/jor.24017. Epub 2018 Dec 27.

PMID:
29663560
9.

Increased Tumor Glycolysis Characterizes Immune Resistance to Adoptive T Cell Therapy.

Cascone T, McKenzie JA, Mbofung RM, Punt S, Wang Z, Xu C, Williams LJ, Wang Z, Bristow CA, Carugo A, Peoples MD, Li L, Karpinets T, Huang L, Malu S, Creasy C, Leahey SE, Chen J, Chen Y, Pelicano H, Bernatchez C, Gopal YNV, Heffernan TP, Hu J, Wang J, Amaria RN, Garraway LA, Huang P, Yang P, Wistuba II, Woodman SE, Roszik J, Davis RE, Davies MA, Heymach JV, Hwu P, Peng W.

Cell Metab. 2018 May 1;27(5):977-987.e4. doi: 10.1016/j.cmet.2018.02.024. Epub 2018 Apr 5.

10.

The RNA-binding Protein MEX3B Mediates Resistance to Cancer Immunotherapy by Downregulating HLA-A Expression.

Huang L, Malu S, McKenzie JA, Andrews MC, Talukder AH, Tieu T, Karpinets T, Haymaker C, Forget MA, Williams LJ, Wang Z, Mbofung RM, Wang ZQ, Davis RE, Lo RS, Wargo JA, Davies MA, Bernatchez C, Heffernan T, Amaria RN, Korkut A, Peng W, Roszik J, Lizée G, Woodman SE, Hwu P.

Clin Cancer Res. 2018 Jul 15;24(14):3366-3376. doi: 10.1158/1078-0432.CCR-17-2483. Epub 2018 Mar 1.

11.

The Effect of Topoisomerase I Inhibitors on the Efficacy of T-Cell-Based Cancer Immunotherapy.

McKenzie JA, Mbofung RM, Malu S, Zhang M, Ashkin E, Devi S, Williams L, Tieu T, Peng W, Pradeep S, Xu C, Zorro Manrique S, Liu C, Huang L, Chen Y, Forget MA, Haymaker C, Bernatchez C, Satani N, Muller F, Roszik J, Kalra A, Heffernan T, Sood A, Hu J, Amaria R, Davis RE, Hwu P.

J Natl Cancer Inst. 2018 Jul 1;110(7):777-786. doi: 10.1093/jnci/djx257.

12.

Gli1 identifies osteogenic progenitors for bone formation and fracture repair.

Shi Y, He G, Lee WC, McKenzie JA, Silva MJ, Long F.

Nat Commun. 2017 Dec 11;8(1):2043. doi: 10.1038/s41467-017-02171-2.

13.

HSP90 inhibition enhances cancer immunotherapy by upregulating interferon response genes.

Mbofung RM, McKenzie JA, Malu S, Zhang M, Peng W, Liu C, Kuiatse I, Tieu T, Williams L, Devi S, Ashkin E, Xu C, Huang L, Zhang M, Talukder AH, Tripathi SC, Khong H, Satani N, Muller FL, Roszik J, Heffernan T, Allison JP, Lizee G, Hanash SM, Proia D, Amaria R, Davis RE, Hwu P.

Nat Commun. 2017 Sep 6;8(1):451. doi: 10.1038/s41467-017-00449-z.

14.

Exogenous hedgehog antagonist delays but does not prevent fracture healing in young mice.

Liu X, McKenzie JA, Maschhoff CW, Gardner MJ, Silva MJ.

Bone. 2017 Oct;103:241-251. doi: 10.1016/j.bone.2017.07.017. Epub 2017 Jul 19.

15.

Endothelial MAPKs Direct ICAM-1 Signaling to Divergent Inflammatory Functions.

Dragoni S, Hudson N, Kenny BA, Burgoyne T, McKenzie JA, Gill Y, Blaber R, Futter CE, Adamson P, Greenwood J, Turowski P.

J Immunol. 2017 May 15;198(10):4074-4085. doi: 10.4049/jimmunol.1600823. Epub 2017 Apr 3.

16.

Neuroinflammation as a Common Mechanism Associated with the Modifiable Risk Factors for Alzheimer's and Parkinson's Diseases.

McKenzie JA, Spielman LJ, Pointer CB, Lowry JR, Bajwa E, Lee CW, Klegeris A.

Curr Aging Sci. 2017;10(3):158-176. doi: 10.2174/1874609810666170315113244. Review.

PMID:
28302047
17.

CpG-based immunotherapy impairs antitumor activity of BRAF inhibitors in a B-cell-dependent manner.

Huang L, Wang Z, Liu C, Xu C, Mbofung RM, McKenzie JA, Khong H, Hwu P, Peng W.

Oncogene. 2017 Jul 13;36(28):4081-4086. doi: 10.1038/onc.2017.35. Epub 2017 Mar 6.

18.

Loss of scleraxis in mice leads to geometric and structural changes in cortical bone, as well as asymmetry in fracture healing.

McKenzie JA, Buettmann E, Abraham AC, Gardner MJ, Silva MJ, Killian ML.

FASEB J. 2017 Mar;31(3):882-892. doi: 10.1096/fj.201600969R. Epub 2016 Nov 18.

19.

Complementing T-cell Function: An Inhibitory Role of the Complement System in T-cell-Mediated Antitumor Immunity.

Peng W, McKenzie JA, Hwu P.

Cancer Discov. 2016 Sep;6(9):953-5. doi: 10.1158/2159-8290.CD-16-0698.

20.

Loss of PTEN Promotes Resistance to T Cell-Mediated Immunotherapy.

Peng W, Chen JQ, Liu C, Malu S, Creasy C, Tetzlaff MT, Xu C, McKenzie JA, Zhang C, Liang X, Williams LJ, Deng W, Chen G, Mbofung R, Lazar AJ, Torres-Cabala CA, Cooper ZA, Chen PL, Tieu TN, Spranger S, Yu X, Bernatchez C, Forget MA, Haymaker C, Amaria R, McQuade JL, Glitza IC, Cascone T, Li HS, Kwong LN, Heffernan TP, Hu J, Bassett RL Jr, Bosenberg MW, Woodman SE, Overwijk WW, Lizée G, Roszik J, Gajewski TF, Wargo JA, Gershenwald JE, Radvanyi L, Davies MA, Hwu P.

Cancer Discov. 2016 Feb;6(2):202-16. doi: 10.1158/2159-8290.CD-15-0283. Epub 2015 Dec 8.

21.

Hedgehog signaling mediates woven bone formation and vascularization during stress fracture healing.

Kazmers NH, McKenzie JA, Shen TS, Long F, Silva MJ.

Bone. 2015 Dec;81:524-532. doi: 10.1016/j.bone.2015.09.002. Epub 2015 Sep 6.

22.

Bmp2 conditional knockout in osteoblasts and endothelial cells does not impair bone formation after injury or mechanical loading in adult mice.

McBride-Gagyi SH, McKenzie JA, Buettmann EG, Gardner MJ, Silva MJ.

Bone. 2015 Dec;81:533-543. doi: 10.1016/j.bone.2015.09.003. Epub 2015 Sep 5.

23.

Methanogenesis produces strong 13C enrichment in stromatolites of Lagoa Salgada, Brazil: a modern analogue for Palaeo-/Neoproterozoic stromatolites?

Birgel D, Meister P, Lundberg R, Horath TD, Bontognali TR, Bahniuk AM, de Rezende CE, Vasconcelos C, McKenzie JA.

Geobiology. 2015 May;13(3):245-66. doi: 10.1111/gbi.12130. Epub 2015 Mar 13.

PMID:
25773379
24.

Surgical correction of childhood intermittent exotropia and the risk of developing mental illness.

Kilgore KP, Barraza RA, Hodge DO, McKenzie JA, Mohney BG.

Am J Ophthalmol. 2014 Oct;158(4):788-792.e1. doi: 10.1016/j.ajo.2014.06.008. Epub 2014 Jun 19.

25.

Long bone structure and strength depend on BMP2 from osteoblasts and osteocytes, but not vascular endothelial cells.

McBride SH, McKenzie JA, Bedrick BS, Kuhlmann P, Pasteris JD, Rosen V, Silva MJ.

PLoS One. 2014 May 16;9(5):e96862. doi: 10.1371/journal.pone.0096862. eCollection 2014.

26.

Microbial mediated formation of Fe-carbonate minerals under extreme acidic conditions.

Sánchez-Román M, Fernández-Remolar D, Amils R, Sánchez-Navas A, Schmid T, San Martin-Uriz P, Rodríguez N, McKenzie JA, Vasconcelos C.

Sci Rep. 2014 Apr 23;4:4767. doi: 10.1038/srep04767.

27.

Expression of neonatal Fc receptor in the eye.

Powner MB, McKenzie JA, Christianson GJ, Roopenian DC, Fruttiger M.

Invest Ophthalmol Vis Sci. 2014 Mar 19;55(3):1607-15. doi: 10.1167/iovs.13-12574.

28.

LRG1 promotes angiogenesis by modulating endothelial TGF-β signalling.

Wang X, Abraham S, McKenzie JAG, Jeffs N, Swire M, Tripathi VB, Luhmann UFO, Lange CAK, Zhai Z, Arthur HM, Bainbridge J, Moss SE, Greenwood J.

Nature. 2013 Jul 18;499(7458):306-11. doi: 10.1038/nature12345.

29.

Survivin promotion of melanoma metastasis requires upregulation of α5 integrin.

McKenzie JA, Liu T, Jung JY, Jones BB, Ekiz HA, Welm AL, Grossman D.

Carcinogenesis. 2013 Sep;34(9):2137-44. doi: 10.1093/carcin/bgt155. Epub 2013 May 2.

30.

Intellectual disability in Africa: implications for research and service development.

McKenzie JA, McConkey R, Adnams C.

Disabil Rehabil. 2013 Sep;35(20):1750-5. doi: 10.3109/09638288.2012.751461. Epub 2013 Jan 25.

PMID:
23350758
31.

Disabled people in rural South Africa talk about sexuality.

McKenzie JA.

Cult Health Sex. 2013;15(3):372-86. doi: 10.1080/13691058.2012.748936. Epub 2012 Dec 11.

PMID:
23227824
32.
33.

Angiogenesis is required for stress fracture healing in rats.

Tomlinson RE, McKenzie JA, Schmieder AH, Wohl GR, Lanza GM, Silva MJ.

Bone. 2013 Jan;52(1):212-9. doi: 10.1016/j.bone.2012.09.035. Epub 2012 Oct 5.

34.

Visualization of gene expression in whole mouse retina by in situ hybridization.

Powner MB, Vevis K, McKenzie JA, Gandhi P, Jadeja S, Fruttiger M.

Nat Protoc. 2012 May 10;7(6):1086-96. doi: 10.1038/nprot.2012.050.

PMID:
22576107
35.

Models of intellectual disability: towards a perspective of (poss)ability.

McKenzie JA.

J Intellect Disabil Res. 2013 Apr;57(4):370-9. doi: 10.1111/j.1365-2788.2012.01547.x. Epub 2012 Mar 28.

PMID:
22458334
36.

Sniff nasal inspiratory pressure and sleep disordered breathing in childhood neuromuscular disorders.

Anderson VB, McKenzie JA, Seton C, Fitzgerald DA, Webster RI, North KN, Joffe DA, Young HK.

Neuromuscul Disord. 2012 Jun;22(6):528-33. doi: 10.1016/j.nmd.2012.02.002. Epub 2012 Mar 3.

PMID:
22386707
37.

Role of the apoptotic and mitotic regulator survivin in melanoma.

McKenzie JA, Grossman D.

Anticancer Res. 2012 Feb;32(2):397-404. Review.

PMID:
22287725
38.

Differential gene expression from microarray analysis distinguishes woven and lamellar bone formation in the rat ulna following mechanical loading.

McKenzie JA, Bixby EC, Silva MJ.

PLoS One. 2011;6(12):e29328. doi: 10.1371/journal.pone.0029328. Epub 2011 Dec 22.

39.

Apelin is required for non-neovascular remodeling in the retina.

McKenzie JA, Fruttiger M, Abraham S, Lange CA, Stone J, Gandhi P, Wang X, Bainbridge J, Moss SE, Greenwood J.

Am J Pathol. 2012 Jan;180(1):399-409. doi: 10.1016/j.ajpath.2011.09.035. Epub 2011 Nov 7.

40.

Hospital nurses' perceptions of the geriatric care environment in one Canadian health care region.

McKenzie JA, Blandford AA, Menec VH, Boltz M, Capezuti E.

J Nurs Scholarsh. 2011 Jun;43(2):181-7. doi: 10.1111/j.1547-5069.2011.01387.x. Epub 2011 Apr 6.

PMID:
21605322
41.

AKT1 G205T genotype influences obesity-related metabolic phenotypes and their responses to aerobic exercise training in older Caucasians.

McKenzie JA, Witkowski S, Ludlow AT, Roth SM, Hagberg JM.

Exp Physiol. 2011 Mar;96(3):338-47. doi: 10.1113/expphysiol.2010.055400. Epub 2010 Nov 19.

42.

Obstructive sleep apnoea and perioperative complications in bariatric patients.

Weingarten TN, Flores AS, McKenzie JA, Nguyen LT, Robinson WB, Kinney TM, Siems BT, Wenzel PJ, Sarr MG, Marienau MS, Schroeder DR, Olson EJ, Morgenthaler TI, Warner DO, Sprung J.

Br J Anaesth. 2011 Jan;106(1):131-9. doi: 10.1093/bja/aeq290. Epub 2010 Oct 18.

43.
44.

Survivin enhances motility of melanoma cells by supporting Akt activation and {alpha}5 integrin upregulation.

McKenzie JA, Liu T, Goodson AG, Grossman D.

Cancer Res. 2010 Oct 15;70(20):7927-37. doi: 10.1158/0008-5472.CAN-10-0194. Epub 2010 Aug 31.

45.

Healing of non-displaced fractures produced by fatigue loading of the mouse ulna.

Martinez MD, Schmid GJ, McKenzie JA, Ornitz DM, Silva MJ.

Bone. 2010 Jun;46(6):1604-12. doi: 10.1016/j.bone.2010.02.030. Epub 2010 Mar 6.

46.

Plasma fetuin-A concentrations in young and older high- and low-active men.

Jenkins NT, McKenzie JA, Hagberg JM, Witkowski S.

Metabolism. 2011 Feb;60(2):265-71. doi: 10.1016/j.metabol.2010.01.026. Epub 2010 Mar 4.

47.

"Hit the ground running": perspectives of new nurses and nurse managers on role transition and integration of new graduates.

Chernomas WM, Care WD, McKenzie JA, Guse L, Currie J.

Nurs Leadersh (Tor Ont). 2010 Jan;22(4):70-86.

PMID:
20160525
48.

Endurance exercise training effects on body fatness, VO2max, HDL-C subfractions, and glucose tolerance are influenced by a PLIN haplotype in older Caucasians.

Jenkins NT, McKenzie JA, Damcott CM, Witkowski S, Hagberg JM.

J Appl Physiol (1985). 2010 Mar;108(3):498-506. doi: 10.1152/japplphysiol.01018.2009. Epub 2009 Oct 22.

49.

Prevalence and sex differences of psychiatric disorders in young adults who had intermittent exotropia as children.

McKenzie JA, Capo JA, Nusz KJ, Diehl NN, Mohney BG.

Arch Ophthalmol. 2009 Jun;127(6):743-7. doi: 10.1001/archophthalmol.2009.68.

50.

How well do headache patients remember? A comparison of self-report measures of headache frequency and severity in patients with migraine.

McKenzie JA, Cutrer FM.

Headache. 2009 May;49(5):669-72. doi: 10.1111/j.1526-4610.2009.01411.x.

PMID:
19456879

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