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Items: 36

1.

Precise small-molecule cleavage of an r(CUG) repeat expansion in a myotonic dystrophy mouse model.

Angelbello AJ, Rzuczek SG, Mckee KK, Chen JL, Olafson H, Cameron MD, Moss WN, Wang ET, Disney MD.

Proc Natl Acad Sci U S A. 2019 Apr 16;116(16):7799-7804. doi: 10.1073/pnas.1901484116. Epub 2019 Mar 29.

2.

Chimeric protein identification of dystrophic, Pierson and other laminin polymerization residues.

McKee KK, Aleksandrova M, Yurchenco PD.

Matrix Biol. 2018 Apr;67:32-46. doi: 10.1016/j.matbio.2018.01.012. Epub 2018 Mar 3.

3.

Pathogenicity of a Human Laminin β2 Mutation Revealed in Models of Alport Syndrome.

Funk SD, Bayer RH, Malone AF, McKee KK, Yurchenco PD, Miner JH.

J Am Soc Nephrol. 2018 Mar;29(3):949-960. doi: 10.1681/ASN.2017090997. Epub 2017 Dec 20.

4.

Laminin-deficient muscular dystrophy: Molecular pathogenesis and structural repair strategies.

Yurchenco PD, McKee KK, Reinhard JR, Rüegg MA.

Matrix Biol. 2018 Oct;71-72:174-187. doi: 10.1016/j.matbio.2017.11.009. Epub 2017 Nov 27. Review.

PMID:
29191403
5.

Whole Transcriptome Analysis of Notochord-Derived Cells during Embryonic Formation of the Nucleus Pulposus.

Peck SH, McKee KK, Tobias JW, Malhotra NR, Harfe BD, Smith LJ.

Sci Rep. 2017 Sep 5;7(1):10504. doi: 10.1038/s41598-017-10692-5.

6.

Linker proteins restore basement membrane and correct LAMA2-related muscular dystrophy in mice.

Reinhard JR, Lin S, McKee KK, Meinen S, Crosson SC, Sury M, Hobbs S, Maier G, Yurchenco PD, Rüegg MA.

Sci Transl Med. 2017 Jun 28;9(396). pii: eaal4649. doi: 10.1126/scitranslmed.aal4649.

7.

Chimeric protein repair of laminin polymerization ameliorates muscular dystrophy phenotype.

McKee KK, Crosson SC, Meinen S, Reinhard JR, Rüegg MA, Yurchenco PD.

J Clin Invest. 2017 Mar 1;127(3):1075-1089. doi: 10.1172/JCI90854. Epub 2017 Feb 20.

8.

Whole-Genome Sequencing of Invasion-Resistant Cells Identifies Laminin α2 as a Host Factor for Bacterial Invasion.

van Wijk XM, Döhrmann S, Hallström BM, Li S, Voldborg BG, Meng BX, McKee KK, van Kuppevelt TH, Yurchenco PD, Palsson BO, Lewis NE, Nizet V, Esko JD.

MBio. 2017 Jan 10;8(1). pii: e02128-16. doi: 10.1128/mBio.02128-16.

9.

Integrin alpha6 maintains the structural integrity of the kidney collecting system.

Viquez OM, Yazlovitskaya EM, Tu T, Mernaugh G, Secades P, McKee KK, Georges-Labouesse E, De Arcangelis A, Quaranta V, Yurchenco P, Gewin LC, Sonnenberg A, Pozzi A, Zent R.

Matrix Biol. 2017 Jan;57-58:244-257. doi: 10.1016/j.matbio.2016.12.003. Epub 2016 Dec 30.

10.

Structural decoding of netrin-4 reveals a regulatory function towards mature basement membranes.

Reuten R, Patel TR, McDougall M, Rama N, Nikodemus D, Gibert B, Delcros JG, Prein C, Meier M, Metzger S, Zhou Z, Kaltenberg J, McKee KK, Bald T, Tüting T, Zigrino P, Djonov V, Bloch W, Clausen-Schaumann H, Poschl E, Yurchenco PD, Ehrbar M, Mehlen P, Stetefeld J, Koch M.

Nat Commun. 2016 Nov 30;7:13515. doi: 10.1038/ncomms13515.

11.

Potency of irritation by benzylidenemalononitriles in humans correlates with TRPA1 ion channel activation.

Lindsay CD, Green C, Bird M, Jones JT, Riches JR, McKee KK, Sandford MS, Wakefield DA, Timperley CM.

R Soc Open Sci. 2015 Jan 28;2(1):140160. doi: 10.1098/rsos.140160. eCollection 2015 Jan.

12.

Integrin α3β1 regulates kidney collecting duct development via TRAF6-dependent K63-linked polyubiquitination of Akt.

Yazlovitskaya EM, Tseng HY, Viquez O, Tu T, Mernaugh G, McKee KK, Riggins K, Quaranta V, Pathak A, Carter BD, Yurchenco P, Sonnenberg A, Böttcher RT, Pozzi A, Zent R.

Mol Biol Cell. 2015 May 15;26(10):1857-74. doi: 10.1091/mbc.E14-07-1203. Epub 2015 Mar 25.

13.

Perlecan is recruited by dystroglycan to nodes of Ranvier and binds the clustering molecule gliomedin.

Colombelli C, Palmisano M, Eshed-Eisenbach Y, Zambroni D, Pavoni E, Ferri C, Saccucci S, Nicole S, Soininen R, McKee KK, Yurchenco PD, Peles E, Wrabetz L, Feltri ML.

J Cell Biol. 2015 Feb 2;208(3):313-29. doi: 10.1083/jcb.201403111.

14.

A laminin 511 matrix is regulated by TAZ and functions as the ligand for the α6Bβ1 integrin to sustain breast cancer stem cells.

Chang C, Goel HL, Gao H, Pursell B, Shultz LD, Greiner DL, Ingerpuu S, Patarroyo M, Cao S, Lim E, Mao J, McKee KK, Yurchenco PD, Mercurio AM.

Genes Dev. 2015 Jan 1;29(1):1-6. doi: 10.1101/gad.253682.114.

15.

α6β1 and α7β1 integrins are required in Schwann cells to sort axons.

Pellegatta M, De Arcangelis A, D'Urso A, Nodari A, Zambroni D, Ghidinelli M, Matafora V, Williamson C, Georges-Labouesse E, Kreidberg J, Mayer U, McKee KK, Yurchenco PD, Quattrini A, Wrabetz L, Feltri ML.

J Neurosci. 2013 Nov 13;33(46):17995-8007. doi: 10.1523/JNEUROSCI.3179-13.2013.

16.

Schwann cell myelination requires integration of laminin activities.

McKee KK, Yang DH, Patel R, Chen ZL, Strickland S, Takagi J, Sekiguchi K, Yurchenco PD.

J Cell Sci. 2012 Oct 1;125(Pt 19):4609-19. doi: 10.1242/jcs.107995. Epub 2012 Jul 5.

17.

Renal collecting system growth and function depend upon embryonic γ1 laminin expression.

Yang DH, McKee KK, Chen ZL, Mernaugh G, Strickland S, Zent R, Yurchenco PD.

Development. 2011 Oct;138(20):4535-44. doi: 10.1242/dev.071266. Epub 2011 Sep 8.

18.

Scaffold-forming and Adhesive Contributions of Synthetic Laminin-binding Proteins to Basement Membrane Assembly.

McKee KK, Capizzi S, Yurchenco PD.

J Biol Chem. 2009 Mar 27;284(13):8984-94. doi: 10.1074/jbc.M809719200. Epub 2009 Feb 2.

19.

Role of laminin terminal globular domains in basement membrane assembly.

McKee KK, Harrison D, Capizzi S, Yurchenco PD.

J Biol Chem. 2007 Jul 20;282(29):21437-47. Epub 2007 May 21.

20.

Conjugation of LG domains of agrins and perlecan to polymerizing laminin-2 promotes acetylcholine receptor clustering.

Smirnov SP, Barzaghi P, McKee KK, Ruegg MA, Yurchenco PD.

J Biol Chem. 2005 Dec 16;280(50):41449-57. Epub 2005 Oct 11.

21.

Laminin-sulfatide binding initiates basement membrane assembly and enables receptor signaling in Schwann cells and fibroblasts.

Li S, Liquari P, McKee KK, Harrison D, Patel R, Lee S, Yurchenco PD.

J Cell Biol. 2005 Apr 11;169(1):179-89.

22.

Spiro(indoline-3,4'-piperidine) growth hormone secretagogues as ghrelin mimetics.

Palucki BL, Feighner SD, Pong S, McKee KK, Hreniuk DL, Tan C, Howard AD, Van der Ploeg LH, Patchett AA, Nargund RP.

Bioorg Med Chem Lett. 2001 Jul 23;11(14):1955-7.

PMID:
11459669
23.

Growth hormone secretagogue receptor family members and ligands.

Smith RG, Leonard R, Bailey AR, Palyha O, Feighner S, Tan C, Mckee KK, Pong SS, Griffin P, Howard A.

Endocrine. 2001 Feb;14(1):9-14. Review.

PMID:
11322507
24.

Structure-function studies on the new growth hormone-releasing peptide, ghrelin: minimal sequence of ghrelin necessary for activation of growth hormone secretagogue receptor 1a.

Bednarek MA, Feighner SD, Pong SS, McKee KK, Hreniuk DL, Silva MV, Warren VA, Howard AD, Van Der Ploeg LH, Heck JV.

J Med Chem. 2000 Nov 16;43(23):4370-6.

PMID:
11087562
25.

Identification of receptors for neuromedin U and its role in feeding.

Howard AD, Wang R, Pong SS, Mellin TN, Strack A, Guan XM, Zeng Z, Williams DL Jr, Feighner SD, Nunes CN, Murphy B, Stair JN, Yu H, Jiang Q, Clements MK, Tan CP, McKee KK, Hreniuk DL, McDonald TP, Lynch KR, Evans JF, Austin CP, Caskey CT, Van der Ploeg LH, Liu Q.

Nature. 2000 Jul 6;406(6791):70-4.

PMID:
10894543
26.

Ligand activation domain of human orphan growth hormone (GH) secretagogue receptor (GHS-R) conserved from Pufferfish to humans.

Palyha OC, Feighner SD, Tan CP, McKee KK, Hreniuk DL, Gao YD, Schleim KD, Yang L, Morriello GJ, Nargund R, Patchett AA, Howard AD, Smith RG.

Mol Endocrinol. 2000 Jan;14(1):160-9.

PMID:
10628755
27.

Growth hormone releasing substances: types and their receptors.

Smith RG, Palyha OC, Feighner SD, Tan CP, McKee KK, Hreniuk DL, Yang L, Morriello G, Nargund R, Patchett AA, Howard AD.

Horm Res. 1999;51 Suppl 3:1-8. Review.

PMID:
10592437
28.

Receptor for motilin identified in the human gastrointestinal system.

Feighner SD, Tan CP, McKee KK, Palyha OC, Hreniuk DL, Pong SS, Austin CP, Figueroa D, MacNeil D, Cascieri MA, Nargund R, Bakshi R, Abramovitz M, Stocco R, Kargman S, O'Neill G, Van Der Ploeg LH, Evans J, Patchett AA, Smith RG, Howard AD.

Science. 1999 Jun 25;284(5423):2184-8.

29.

Molecular analysis of a new splice variant of the human melanocortin-1 receptor.

Tan CP, McKee KK, Weinberg DH, MacNeil T, Palyha OC, Feighner SD, Hreniuk DL, Van Der Ploeg LH, MacNeil DJ, Howard AD.

FEBS Lett. 1999 May 21;451(2):137-41.

30.

Cloning and characterization of a human and murine T-cell orphan G-protein-coupled receptor similar to the growth hormone secretagogue and neurotensin receptors.

Tan CP, McKee KK, Liu Q, Palyha OC, Feighner SD, Hreniuk DL, Smith RG, Howard AD.

Genomics. 1998 Sep 1;52(2):223-9.

PMID:
9782091
31.

Cloning and characterization of two human G protein-coupled receptor genes (GPR38 and GPR39) related to the growth hormone secretagogue and neurotensin receptors.

McKee KK, Tan CP, Palyha OC, Liu J, Feighner SD, Hreniuk DL, Smith RG, Howard AD, Van der Ploeg LH.

Genomics. 1997 Dec 15;46(3):426-34.

PMID:
9441746
32.

Structural requirements for the activation of the human growth hormone secretagogue receptor by peptide and nonpeptide secretagogues.

Feighner SD, Howard AD, Prendergast K, Palyha OC, Hreniuk DL, Nargund R, Underwood D, Tata JR, Dean DC, Tan CP, McKee KK, Woods JW, Patchett AA, Smith RG, Van der Ploeg LH.

Mol Endocrinol. 1998 Jan;12(1):137-45.

PMID:
9440817
33.

Distribution of mRNA encoding the growth hormone secretagogue receptor in brain and peripheral tissues.

Guan XM, Yu H, Palyha OC, McKee KK, Feighner SD, Sirinathsinghji DJ, Smith RG, Van der Ploeg LH, Howard AD.

Brain Res Mol Brain Res. 1997 Aug;48(1):23-9.

PMID:
9379845
34.

Molecular cloning and characterization of a new receptor for galanin.

Howard AD, Tan C, Shiao LL, Palyha OC, McKee KK, Weinberg DH, Feighner SD, Cascieri MA, Smith RG, Van Der Ploeg LH, Sullivan KA.

FEBS Lett. 1997 Apr 1;405(3):285-90.

35.

Molecular analysis of rat pituitary and hypothalamic growth hormone secretagogue receptors.

McKee KK, Palyha OC, Feighner SD, Hreniuk DL, Tan CP, Phillips MS, Smith RG, Van der Ploeg LH, Howard AD.

Mol Endocrinol. 1997 Apr;11(4):415-23.

PMID:
9092793
36.

A receptor in pituitary and hypothalamus that functions in growth hormone release.

Howard AD, Feighner SD, Cully DF, Arena JP, Liberator PA, Rosenblum CI, Hamelin M, Hreniuk DL, Palyha OC, Anderson J, Paress PS, Diaz C, Chou M, Liu KK, McKee KK, Pong SS, Chaung LY, Elbrecht A, Dashkevicz M, Heavens R, Rigby M, Sirinathsinghji DJ, Dean DC, Melillo DG, Patchett AA, Nargund R, Griffin PR, DeMartino JA, Gupta SK, Schaeffer JM, Smith RG, Van der Ploeg LH.

Science. 1996 Aug 16;273(5277):974-7.

PMID:
8688086

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