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Items: 15

1.

Convergent evolution in floral morphology in a plant ring species, the Caribbean Euphorbia tithymaloides.

Cacho NI, Monteverde-Suárez MJ, McIntyre PJ.

Am J Bot. 2019 Jul;106(7):1032-1045. doi: 10.1002/ajb2.1318. Epub 2019 Jul 7.

PMID:
31281963
2.

Construction of a Shape-Diverse Fragment Set: Design, Synthesis and Screen against Aurora-A Kinase.

Zhang R, McIntyre PJ, Collins PM, Foley DJ, Arter C, von Delft F, Bayliss R, Warriner S, Nelson A.

Chemistry. 2019 May 10;25(27):6831-6839. doi: 10.1002/chem.201900815. Epub 2019 Apr 26.

PMID:
31026091
3.

Type II Kinase Inhibitors Targeting Cys-Gatekeeper Kinases Display Orthogonality with Wild Type and Ala/Gly-Gatekeeper Kinases.

Ocasio CA, Warkentin AA, McIntyre PJ, Barkovich KJ, Vesely C, Spencer J, Shokat KM, Bayliss R.

ACS Chem Biol. 2018 Oct 19;13(10):2956-2965. doi: 10.1021/acschembio.8b00592. Epub 2018 Oct 9.

PMID:
30239186
4.

An Integrated Quantitative Index for Measuring Chronic Multisite Pain: The Multiple Areas of Pain (MAP) Study.

Wallace MS, North J, Grigsby EJ, Kapural L, Sanapati MR, Smith SG, Willoughby C, McIntyre PJ, Cohen SP, Rosenthal RM, Ahmed S, Vallejo R, Ahadian FM, Yearwood TL, Burton AW, Frankoski EJ, Shetake J, Lin S, Hershey B, Rogers B, Mekel-Bobrov N.

Pain Med. 2018 Feb 21. doi: 10.1093/pm/pnx325. [Epub ahead of print]

PMID:
29474648
5.

Characterization of Three Druggable Hot-Spots in the Aurora-A/TPX2 Interaction Using Biochemical, Biophysical, and Fragment-Based Approaches.

McIntyre PJ, Collins PM, Vrzal L, Birchall K, Arnold LH, Mpamhanga C, Coombs PJ, Burgess SG, Richards MW, Winter A, Veverka V, Delft FV, Merritt A, Bayliss R.

ACS Chem Biol. 2017 Nov 17;12(11):2906-2914. doi: 10.1021/acschembio.7b00537. Epub 2017 Oct 30.

6.

An experimental test of local adaptation among cytotypes within a polyploid complex.

McIntyre PJ, Strauss S.

Evolution. 2017 Aug;71(8):1960-1969. doi: 10.1111/evo.13288. Epub 2017 Jun 16.

PMID:
28598499
7.

Switching Aurora-A kinase on and off at an allosteric site.

Bayliss R, Burgess SG, McIntyre PJ.

FEBS J. 2017 Sep;284(18):2947-2954. doi: 10.1111/febs.14069. Epub 2017 Apr 18. Review.

8.

A TPX2 Proteomimetic Has Enhanced Affinity for Aurora-A Due to Hydrocarbon Stapling of a Helix.

Rennie YK, McIntyre PJ, Akindele T, Bayliss R, Jamieson AG.

ACS Chem Biol. 2016 Dec 16;11(12):3383-3390. Epub 2016 Nov 1.

9.

7-(Pyrazol-4-yl)-3H-imidazo[4,5-b]pyridine-based derivatives for kinase inhibition: Co-crystallisation studies with Aurora-A reveal distinct differences in the orientation of the pyrazole N1-substituent.

Bavetsias V, Pérez-Fuertes Y, McIntyre PJ, Atrash B, Kosmopoulou M, O'Fee L, Burke R, Sun C, Faisal A, Bush K, Avery S, Henley A, Raynaud FI, Linardopoulos S, Bayliss R, Blagg J.

Bioorg Med Chem Lett. 2015 Oct 1;25(19):4203-9. doi: 10.1016/j.bmcl.2015.08.003. Epub 2015 Aug 6.

10.

Twentieth-century shifts in forest structure in California: Denser forests, smaller trees, and increased dominance of oaks.

McIntyre PJ, Thorne JH, Dolanc CR, Flint AL, Flint LE, Kelly M, Ackerly DD.

Proc Natl Acad Sci U S A. 2015 Feb 3;112(5):1458-63. doi: 10.1073/pnas.1410186112. Epub 2015 Jan 20.

11.

Mutualist-mediated effects on species' range limits across large geographic scales.

Afkhami ME, McIntyre PJ, Strauss SY.

Ecol Lett. 2014 Oct;17(10):1265-73. doi: 10.1111/ele.12332. Epub 2014 Jul 22.

PMID:
25052023
12.

Cytogeography and genome size variation in the Claytonia perfoliata (Portulacaceae) polyploid complex.

McIntyre PJ.

Ann Bot. 2012 Nov;110(6):1195-203. doi: 10.1093/aob/mcs187. Epub 2012 Sep 7.

13.

Polyploidy associated with altered and broader ecological niches in the Claytonia perfoliata (Portulacaceae) species complex.

McIntyre PJ.

Am J Bot. 2012 Apr;99(4):655-62. doi: 10.3732/ajb.1100466. Epub 2012 Mar 20.

14.

Tall cell papillary thyroid carcinoma metastatic to femur: evidence for thyroid hormone synthesis within the femur.

Lawrence E, Lord ST, Leon Y, McIntyre PJ, Penix J, Grebenev D, Vesely DL.

Am J Med Sci. 2001 Aug;322(2):103-8. Review.

PMID:
11523623
15.

Teaching consultation psychiatry through computerized case simulation.

Jachna JS, Powsner SM, McIntyre PJ, Byck R.

Acad Psychiatry. 1993 Mar;17(1):36-42. doi: 10.1007/BF03341504.

PMID:
24443195

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