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Items: 40

1.

Factors influencing decisions by critical care physicians to withdraw life-sustaining treatments in critically ill adult patients with severe traumatic brain injury.

Turgeon AF, Dorrance K, Archambault P, Lauzier F, Lamontagne F, Zarychanski R, Fowler R, Moore L, Lacroix J, English S, Boutin A, Muscedere J, Burns KEA, Griesdale D, McIntyre LA, Scales D, Bernard F, Yamada J, Squires JE; Canadian Traumatic Brain Injury Research Consortium and the Canadian Critical Care Trials Group.

CMAJ. 2019 Jun 17;191(24):E652-E663. doi: 10.1503/cmaj.190154.

2.

Prognostic Value of Glial Fibrillary Acidic Protein in Patients With Moderate and Severe Traumatic Brain Injury: A Systematic Review and Meta-Analysis.

Shemilt M, Boutin A, Lauzier F, Zarychanski R, Moore L, McIntyre LA, Nadeau L, Fergusson DA, Mercier E, Archambault P, Lamontagne F, Perron C, Léger C, Turgeon AF.

Crit Care Med. 2019 Jun;47(6):e522-e529. doi: 10.1097/CCM.0000000000003728.

PMID:
30889029
3.

Effect of age of transfused red blood cells on neurologic outcome following traumatic brain injury (ABLE-tbi Study): a nested study of the Age of Blood Evaluation (ABLE) trial.

Ruel-Laliberté J, Lessard Bonaventure P, Fergusson D, Lacroix J, Zarychanski R, Lauzier F, Tinmouth A, Hébert PC, Green R, Griesdale D, Fowler R, Kramer A, McIntyre LA, Zygun D, Walsh T, Stanworth S, Capellier G, Pili-Floury S, Samain E, Clayton L, Marshall J, Pagliarello G, Sabri E, Neveu X, Léger C, Turgeon AF; Canadian Critical Care Trials Group.

Can J Anaesth. 2019 Jun;66(6):696-705. doi: 10.1007/s12630-019-01326-7. Epub 2019 Feb 26.

PMID:
30809776
4.

Effects of Mesenchymal Stem Cell Treatment on Systemic Cytokine Levels in a Phase 1 Dose Escalation Safety Trial of Septic Shock Patients.

Schlosser K, Wang JP, Dos Santos C, Walley KR, Marshall J, Fergusson DA, Winston BW, Granton J, Watpool I, Stewart DJ, McIntyre LA, Mei SHJ; Canadian Critical Care Trials Group and the Canadian Critical Care Translational Biology Group.

Crit Care Med. 2019 Jul;47(7):918-925. doi: 10.1097/CCM.0000000000003657.

5.

Cellular Immunotherapy for Septic Shock. A Phase I Clinical Trial.

McIntyre LA, Stewart DJ, Mei SHJ, Courtman D, Watpool I, Granton J, Marshall J, Dos Santos C, Walley KR, Winston BW, Schlosser K, Fergusson DA; Canadian Critical Care Trials Group; Canadian Critical Care Translational Biology Group.

Am J Respir Crit Care Med. 2018 Feb 1;197(3):337-347. doi: 10.1164/rccm.201705-1006OC.

PMID:
28960096
6.

High circulating angiopoietin-2 levels exacerbate pulmonary inflammation but not vascular leak or mortality in endotoxin-induced lung injury in mice.

Schlosser K, Taha M, Deng Y, McIntyre LA, Mei SHJ, Stewart DJ.

Thorax. 2018 Mar;73(3):248-261. doi: 10.1136/thoraxjnl-2017-210413. Epub 2017 Sep 25.

7.

Lack of elevation in plasma levels of pro-inflammatory cytokines in common rodent models of pulmonary arterial hypertension: questions of construct validity for human patients.

Schlosser K, Taha M, Deng Y, Jiang B, McIntyre LA, Mei SH, Stewart DJ.

Pulm Circ. 2017 Apr-Jun;7(2):476-485. doi: 10.1177/2045893217705878. Epub 2017 May 12.

8.

Prognostication in critically ill patients with severe traumatic brain injury: the TBI-Prognosis multicentre feasibility study.

Turgeon AF, Lauzier F, Zarychanski R, Fergusson DA, Léger C, McIntyre LA, Bernard F, Rigamonti A, Burns K, Griesdale DE, Green R, Scales DC, Meade MO, Savard M, Shemilt M, Paquet J, Gariépy JL, Lavoie A, Reddy K, Jichici D, Pagliarello G, Zygun D, Moore L; TBI-Prognosis Study Team and the Canadian Critical Care Trials Group.

BMJ Open. 2017 Apr 17;7(4):e013779. doi: 10.1136/bmjopen-2016-013779.

9.

Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016.

Rhodes A, Evans LE, Alhazzani W, Levy MM, Antonelli M, Ferrer R, Kumar A, Sevransky JE, Sprung CL, Nunnally ME, Rochwerg B, Rubenfeld GD, Angus DC, Annane D, Beale RJ, Bellinghan GJ, Bernard GR, Chiche JD, Coopersmith C, De Backer DP, French CJ, Fujishima S, Gerlach H, Hidalgo JL, Hollenberg SM, Jones AE, Karnad DR, Kleinpell RM, Koh Y, Lisboa TC, Machado FR, Marini JJ, Marshall JC, Mazuski JE, McIntyre LA, McLean AS, Mehta S, Moreno RP, Myburgh J, Navalesi P, Nishida O, Osborn TM, Perner A, Plunkett CM, Ranieri M, Schorr CA, Seckel MA, Seymour CW, Shieh L, Shukri KA, Simpson SQ, Singer M, Thompson BT, Townsend SR, Van der Poll T, Vincent JL, Wiersinga WJ, Zimmerman JL, Dellinger RP.

Intensive Care Med. 2017 Mar;43(3):304-377. doi: 10.1007/s00134-017-4683-6. Epub 2017 Jan 18.

PMID:
28101605
10.

Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016.

Rhodes A, Evans LE, Alhazzani W, Levy MM, Antonelli M, Ferrer R, Kumar A, Sevransky JE, Sprung CL, Nunnally ME, Rochwerg B, Rubenfeld GD, Angus DC, Annane D, Beale RJ, Bellinghan GJ, Bernard GR, Chiche JD, Coopersmith C, De Backer DP, French CJ, Fujishima S, Gerlach H, Hidalgo JL, Hollenberg SM, Jones AE, Karnad DR, Kleinpell RM, Koh Y, Lisboa TC, Machado FR, Marini JJ, Marshall JC, Mazuski JE, McIntyre LA, McLean AS, Mehta S, Moreno RP, Myburgh J, Navalesi P, Nishida O, Osborn TM, Perner A, Plunkett CM, Ranieri M, Schorr CA, Seckel MA, Seymour CW, Shieh L, Shukri KA, Simpson SQ, Singer M, Thompson BT, Townsend SR, Van der Poll T, Vincent JL, Wiersinga WJ, Zimmerman JL, Dellinger RP.

Crit Care Med. 2017 Mar;45(3):486-552. doi: 10.1097/CCM.0000000000002255.

PMID:
28098591
11.

Predictive value of neuron-specific enolase for prognosis in patients with moderate or severe traumatic brain injury: a systematic review and meta-analysis.

Mercier E, Boutin A, Shemilt M, Lauzier F, Zarychanski R, Fergusson DA, Moore L, McIntyre LA, Archambault P, Légaré F, Rousseau F, Lamontagne F, Nadeau L, Turgeon AF.

CMAJ Open. 2016 Jul 22;4(3):E371-E382. eCollection 2016 Jul-Sep.

12.

Aneurysmal SubArachnoid Hemorrhage-Red Blood Cell Transfusion And Outcome (SAHaRA): a pilot randomised controlled trial protocol.

English SW, Fergusson D, Chassé M, Turgeon AF, Lauzier F, Griesdale D, Algird A, Kramer A, Tinmouth A, Lum C, Sinclair J, Marshall S, Dowlatshahi D, Boutin A, Pagliarello G, McIntyre LA; Canadian Critical Care Trials Group.

BMJ Open. 2016 Dec 7;6(12):e012623. doi: 10.1136/bmjopen-2016-012623.

13.

Resuscitation Prior to Emergency Endotracheal Intubation: Results of a National Survey.

Green RS, Fergusson DA, Turgeon AF, McIntyre LA, Kovacs GJ, Griesdale DE, Zarychanski R, Butler MB, Kureshi N, Erdogan M.

West J Emerg Med. 2016 Sep;17(5):542-8. doi: 10.5811/westjem.2016.6.30503. Epub 2016 Jul 26.

14.

Device and Medication Preferences of Canadian Physicians for Emergent Endotracheal Intubation in Critically Ill Patients.

Green RS, Fergusson DA, Turgeon AF, McIntyre LA, Kovacs GJ, Griesdale DE, Zarychanski R, Butler MB, Kureshi N, Erdogan M.

CJEM. 2017 May;19(3):186-197. doi: 10.1017/cem.2016.361. Epub 2016 Aug 30.

PMID:
27573571
15.

Association of Blood Donor Age and Sex With Recipient Survival After Red Blood Cell Transfusion.

Chassé M, Tinmouth A, English SW, Acker JP, Wilson K, Knoll G, Shehata N, van Walraven C, Forster AJ, Ramsay T, McIntyre LA, Fergusson DA.

JAMA Intern Med. 2016 Sep 1;176(9):1307-14. doi: 10.1001/jamainternmed.2016.3324.

PMID:
27398639
16.

Efficacy of Mesenchymal Stromal Cell Therapy for Acute Lung Injury in Preclinical Animal Models: A Systematic Review.

McIntyre LA, Moher D, Fergusson DA, Sullivan KJ, Mei SH, Lalu M, Marshall J, Mcleod M, Griffin G, Grimshaw J, Turgeon A, Avey MT, Rudnicki MA, Jazi M, Fishman J, Stewart DJ; Canadian Critical Care Translational Biology Group.

PLoS One. 2016 Jan 28;11(1):e0147170. doi: 10.1371/journal.pone.0147170. eCollection 2016. Review.

17.

Postintubation hypotension in intensive care unit patients: A multicenter cohort study.

Green RS, Turgeon AF, McIntyre LA, Fox-Robichaud AE, Fergusson DA, Doucette S, Butler MB, Erdogan M; Canadian Critical Care Trials Group (CCCTG).

J Crit Care. 2015 Oct;30(5):1055-60. doi: 10.1016/j.jcrc.2015.06.007. Epub 2015 Jun 16.

PMID:
26117220
18.

Customized Internal Reference Controls for Improved Assessment of Circulating MicroRNAs in Disease.

Schlosser K, McIntyre LA, White RJ, Stewart DJ.

PLoS One. 2015 May 26;10(5):e0127443. doi: 10.1371/journal.pone.0127443. eCollection 2015.

19.

Emergency department management of early sepsis: a national survey of emergency medicine and intensive care consultants.

Jiwaji Z, Brady S, McIntyre LA, Gray A, Walsh TS.

Emerg Med J. 2014 Dec;31(12):1000-5. doi: 10.1136/emermed-2013-202883. Epub 2013 Sep 4.

PMID:
24005642
20.

Intravenous iron therapy for treatment of anaemia.

McIntyre LA, Tinmouth A, Fergusson D.

BMJ. 2013 Sep 3;347:f5378. doi: 10.1136/bmj.f5378. No abstract available.

PMID:
24002811
21.

Comparing diagnostic performance and the utility of clinical vignette-based assessment under testing conditions designed to encourage either automatic or analytic thought.

Ilgen JS, Bowen JL, McIntyre LA, Banh KV, Barnes D, Coates WC, Druck J, Fix ML, Rimple D, Yarris LM, Eva KW.

Acad Med. 2013 Oct;88(10):1545-51. doi: 10.1097/ACM.0b013e3182a31c1e.

PMID:
23969355
22.

Inappropriate medication administration practices in Canadian adult ICUs: a multicenter, cross-sectional observational study.

Kanji S, Lam J, Goddard RD, Johanson C, Singh A, Petrin L, Coons P, McIntyre LA, Turgeon AF.

Ann Pharmacother. 2013 May;47(5):637-43. doi: 10.1345/aph.1R414. Epub 2013 Apr 19.

PMID:
23606550
23.

Predictive value of S-100β protein for prognosis in patients with moderate and severe traumatic brain injury: systematic review and meta-analysis.

Mercier E, Boutin A, Lauzier F, Fergusson DA, Simard JF, Zarychanski R, Moore L, McIntyre LA, Archambault P, Lamontagne F, Légaré F, Randell E, Nadeau L, Rousseau F, Turgeon AF.

BMJ. 2013 Apr 4;346:f1757. doi: 10.1136/bmj.f1757. Review.

24.

Determination of neurologic prognosis and clinical decision making in adult patients with severe traumatic brain injury: a survey of Canadian intensivists, neurosurgeons, and neurologists.

Turgeon AF, Lauzier F, Burns KE, Meade MO, Scales DC, Zarychanski R, Moore L, Zygun DA, McIntyre LA, Kanji S, Hébert PC, Murat V, Pagliarello G, Fergusson DA; Canadian Critical Care Trials Group.

Crit Care Med. 2013 Apr;41(4):1086-93. doi: 10.1097/CCM.0b013e318275d046.

PMID:
23385104
25.

Hemoglobin levels and transfusions in neurocritically ill patients: a systematic review of comparative studies.

Desjardins P, Turgeon AF, Tremblay MH, Lauzier F, Zarychanski R, Boutin A, Moore L, McIntyre LA, English SW, Rigamonti A, Lacroix J, Fergusson DA.

Crit Care. 2012 Dec 12;16(2):R54. doi: 10.1186/cc11293. Review.

26.

Fluid Resuscitation with 5% albumin versus Normal Saline in Early Septic Shock: a pilot randomized, controlled trial.

McIntyre LA, Fergusson DA, Cook DJ, Rowe BH, Bagshaw SM, Easton D, Emond M, Finfer S, Fox-Robichaud A, Gaudert C, Green R, Hebert P, Marshall J, Rankin N, Stiell I, Tinmouth A, Pagliarello J, Turgeon AF, Worster A, Zarychanski R; Canadian Critical Care Trials Group.

J Crit Care. 2012 Jun;27(3):317.e1-6. doi: 10.1016/j.jcrc.2011.10.007. Epub 2011 Dec 15.

PMID:
22176806
27.

Perioperative intravenous lidocaine infusion for postoperative pain control: a meta-analysis of randomized controlled trials.

Vigneault L, Turgeon AF, Côté D, Lauzier F, Zarychanski R, Moore L, McIntyre LA, Nicole PC, Fergusson DA.

Can J Anaesth. 2011 Jan;58(1):22-37. doi: 10.1007/s12630-010-9407-0. Review.

PMID:
21061107
28.

Fluid resuscitation in the management of early septic shock (FINESS): a randomized controlled feasibility trial.

McIntyre LA, Fergusson D, Cook DJ, Rankin N, Dhingra V, Granton J, Magder S, Stiell I, Taljaard M, Hebert PC; Canadian Critical Care Trials Group.

Can J Anaesth. 2008 Dec;55(12):819-26. doi: 10.1007/BF03034053.

PMID:
19050085
29.

Blood conservation strategies to reduce the need for red blood cell transfusion in critically ill patients.

Tinmouth AT, McIntyre LA, Fowler RA.

CMAJ. 2008 Jan 1;178(1):49-57. doi: 10.1503/cmaj.071298.

30.

Resuscitating patients with early severe sepsis: a Canadian multicentre observational study.

McIntyre LA, Fergusson D, Cook DJ, Nair RC, Bell D, Dhingra V, Hutton B, Magder S, Hébert PC; Canadian Critical Care Trials Group.

Can J Anaesth. 2007 Oct;54(10):790-8.

PMID:
17934160
31.

A survey of Canadian intensivists' resuscitation practices in early septic shock.

McIntyre LA, Hébert PC, Fergusson D, Cook DJ, Aziz A; Canadian Critical Care Trials Group.

Crit Care. 2007;11(4):R74.

32.

Can we safely restrict transfusion in trauma patients?

McIntyre LA, Hebert PC.

Curr Opin Crit Care. 2006 Dec;12(6):575-83. Review.

PMID:
17077690
33.

Effect of a liberal versus restrictive transfusion strategy on mortality in patients with moderate to severe head injury.

McIntyre LA, Fergusson DA, Hutchison JS, Pagliarello G, Marshall JC, Yetisir E, Hare GM, Hébert PC.

Neurocrit Care. 2006;5(1):4-9.

PMID:
16960287
34.

Reliability of point-of-care testing for glucose measurement in critically ill adults.

Kanji S, Buffie J, Hutton B, Bunting PS, Singh A, McDonald K, Fergusson D, McIntyre LA, Hebert PC.

Crit Care Med. 2005 Dec;33(12):2778-85.

PMID:
16352960
35.

Prolonged therapeutic hypothermia after traumatic brain injury in adults: a systematic review.

McIntyre LA, Fergusson DA, Hébert PC, Moher D, Hutchison JS.

JAMA. 2003 Jun 11;289(22):2992-9. Review.

PMID:
12799408
36.

Perioperative triggers for red cell transfusions.

Engelfriet CP, Reesink HW, McCullough J, Hébert PC, McIntyre LA, Carson JL, Ferreira G, Thurer RL, Brock H, Boyce N, Jones J, Wulf H, Lukasewitz P, Kretschmer V, Walsh TS, McClelland B.

Vox Sang. 2002 May;82(4):215-26. No abstract available.

PMID:
12047519
37.
38.

The role of nitric oxide in proteoglycan turnover by bovine articular cartilage organ cultures.

Stefanovic-Racic M, Morales TI, Taskiran D, McIntyre LA, Evans CH.

J Immunol. 1996 Feb 1;156(3):1213-20.

PMID:
8558000
39.

Articular chondrocytes synthesize nitric oxide in response to cytokines and lipopolysaccharide.

Stadler J, Stefanovic-Racic M, Billiar TR, Curran RD, McIntyre LA, Georgescu HI, Simmons RL, Evans CH.

J Immunol. 1991 Dec 1;147(11):3915-20.

PMID:
1658153
40.

Tumor necrosis factor, macrophage colony-stimulating factor, and interleukin 1 production within sponge matrix allografts.

Ford HR, Hoffman RA, Wing EJ, Magee DM, McIntyre LA, Simmons RL.

Transplantation. 1990 Sep;50(3):460-6.

PMID:
1698320

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