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Items: 43

1.

Monoclonal Antibody Targeting Sialyl-di-Lewisa-Containing Internalizing and Noninternalizing Glycoproteins with Cancer Immunotherapy Development Potential.

Tivadar ST, McIntosh RS, Chua JX, Moss R, Parsons T, Zaitoun AM, Madhusudan S, Durrant LG, Vankemmelbeke M.

Mol Cancer Ther. 2020 Mar;19(3):790-801. doi: 10.1158/1535-7163.MCT-19-0221. Epub 2019 Dec 23.

2.

The terminal sialic acid of stage-specific embryonic antigen-4 has a crucial role in binding to a cancer-targeting antibody.

Soliman C, Chua JX, Vankemmelbeke M, McIntosh RS, Guy AJ, Spendlove I, Durrant LG, Ramsland PA.

J Biol Chem. 2020 Jan 24;295(4):1009-1020. doi: 10.1074/jbc.RA119.011518. Epub 2019 Dec 12.

PMID:
31831622
3.

Monoclonal Antibodies Targeting LecLex-Related Glycans with Potent Antitumor Activity.

Chua JX, Vankemmelbeke M, McIntosh RS, Clarke PA, Moss R, Parsons T, Spendlove I, Zaitoun AM, Madhusudan S, Durrant LG.

Clin Cancer Res. 2015 Jul 1;21(13):2963-74. doi: 10.1158/1078-0432.CCR-14-3030. Epub 2015 Mar 16.

4.

Functional effects of CCL3L1 copy number.

Carpenter D, McIntosh RS, Pleass RJ, Armour JA.

Genes Immun. 2012 Jul;13(5):374-9. doi: 10.1038/gene.2012.5. Epub 2012 Apr 5.

5.

Polymeric human Fc-fusion proteins with modified effector functions.

Mekhaiel DN, Czajkowsky DM, Andersen JT, Shi J, El-Faham M, Doenhoff M, McIntosh RS, Sandlie I, He J, Hu J, Shao Z, Pleass RJ.

Sci Rep. 2011;1:124. doi: 10.1038/srep00124. Epub 2011 Oct 19.

6.
7.

The generation and evaluation of recombinant human IgA specific for Plasmodium falciparum merozoite surface protein 1-19 (PfMSP1 19).

Shi J, McIntosh RS, Adame-Gallegos J, Dehal PK, van Egmond M, van de Winkel J, Draper SJ, Forbes EK, Corran PH, Holder AA, Woof JM, Pleass RJ.

BMC Biotechnol. 2011 Jul 22;11:77. doi: 10.1186/1472-6750-11-77.

8.

Inhibition of erythrocyte invasion and Plasmodium falciparum merozoite surface protein 1 processing by human immunoglobulin G1 (IgG1) and IgG3 antibodies.

Lazarou M, Guevara Patiño JA, Jennings RM, McIntosh RS, Shi J, Howell S, Cullen E, Jones T, Adame-Gallegos JR, Chappel JA, McBride JS, Blackman MJ, Holder AA, Pleass RJ.

Infect Immun. 2009 Dec;77(12):5659-67. doi: 10.1128/IAI.00167-09. Epub 2009 Oct 5.

9.

Structural requirements for the interaction of human IgM and IgA with the human Fcalpha/mu receptor.

Ghumra A, Shi J, Mcintosh RS, Rasmussen IB, Braathen R, Johansen FE, Sandlie I, Mongini PK, Areschoug T, Lindahl G, Lewis MJ, Woof JM, Pleass RJ.

Eur J Immunol. 2009 Apr;39(4):1147-56. doi: 10.1002/eji.200839184.

10.

Identification of residues in the Cmu4 domain of polymeric IgM essential for interaction with Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1).

Ghumra A, Semblat JP, McIntosh RS, Raza A, Rasmussen IB, Braathen R, Johansen FE, Sandlie I, Mongini PK, Rowe JA, Pleass RJ.

J Immunol. 2008 Aug 1;181(3):1988-2000.

11.

Proteases from Schistosoma mansoni cercariae cleave IgE at solvent exposed interdomain regions.

Aslam A, Quinn P, McIntosh RS, Shi J, Ghumra A, McKerrow JH, Bunting KA, Dunne DW, Doenhoff MJ, Morrison SL, Zhang K, Pleass RJ.

Mol Immunol. 2008 Jan;45(2):567-74. Epub 2007 Jul 12.

PMID:
17631966
12.

The importance of human FcgammaRI in mediating protection to malaria.

McIntosh RS, Shi J, Jennings RM, Chappel JC, de Koning-Ward TF, Smith T, Green J, van Egmond M, Leusen JH, Lazarou M, van de Winkel J, Jones TS, Crabb BS, Holder AA, Pleass RJ.

PLoS Pathog. 2007 May 18;3(5):e72.

13.

Amniotic membrane for ocular surface reconstruction: donor variations and the effect of handling on TGF-beta content.

Hopkinson A, McIntosh RS, Tighe PJ, James DK, Dua HS.

Invest Ophthalmol Vis Sci. 2006 Oct;47(10):4316-22.

PMID:
17003421
14.

Proteomic analysis of amniotic membrane prepared for human transplantation: characterization of proteins and clinical implications.

Hopkinson A, McIntosh RS, Shanmuganathan V, Tighe PJ, Dua HS.

J Proteome Res. 2006 Sep;5(9):2226-35.

PMID:
16944934
15.

Characterization of immunoglobulin binding by schistosomes.

McIntosh RS, Jones FM, Dunne DW, McKerrow JH, Pleass RJ.

Parasite Immunol. 2006 Sep;28(9):407-19.

16.

Antibody- and Fc-receptor-based therapeutics for malaria.

Shi J, McIntosh RS, Pleass RJ.

Clin Sci (Lond). 2006 Jan;110(1):11-9. Review.

PMID:
16336201
17.

Effect of diabetes mellitus and hyperglycemia on the proliferation of human Tenon's capsule fibroblasts: implications for wound healing after glaucoma drainage surgery.

Browning AC, Alibhai A, McIntosh RS, Rotchford AP, Bhan A, Amoaku WM.

Wound Repair Regen. 2005 May-Jun;13(3):295-302.

PMID:
15953049
18.

Optimised two-dimensional electrophoresis procedures for the protein characterisation of structural tissues.

Hopkinson A, McIntosh RS, Layfield R, Keyte J, Dua HS, Tighe PJ.

Proteomics. 2005 May;5(7):1967-79.

PMID:
15816006
19.

The spectrum of antimicrobial peptide expression at the ocular surface.

McIntosh RS, Cade JE, Al-Abed M, Shanmuganathan V, Gupta R, Bhan A, Tighe PJ, Dua HS.

Invest Ophthalmol Vis Sci. 2005 Apr;46(4):1379-85.

PMID:
15790905
20.

Shedding of mutant tumor necrosis factor receptor superfamily 1A associated with tumor necrosis factor receptor-associated periodic syndrome: differences between cell types.

Huggins ML, Radford PM, McIntosh RS, Bainbridge SE, Dickinson P, Draper-Morgan KA, Tighe PJ, Powell RJ, Todd I.

Arthritis Rheum. 2004 Aug;50(8):2651-9.

21.

Treatment of Erdheim-Chester disease with cladribine: a rational approach.

Myra C, Sloper L, Tighe PJ, McIntosh RS, Stevens SE, Gregson RH, Sokal M, Haynes AP, Powell RJ.

Br J Ophthalmol. 2004 Jun;88(6):844-7. Review. No abstract available.

22.

Expression of CD34 and L-selectin on human corneal keratocytes.

Joseph A, Hossain P, Jham S, Jones RE, Tighe P, McIntosh RS, Dua HS.

Invest Ophthalmol Vis Sci. 2003 Nov;44(11):4689-92.

PMID:
14578387
23.

Retroviral activity in Behçet's syndrome and systemic lupus erythematosus detected by a PCR-based reverse transcriptase assay.

McIntosh RS, Huggins ML, Kontogiannis V, Tighe PJ, Powell RJ.

Rheumatol Int. 2001 Oct;21(2):53-7.

PMID:
11732858
24.

Is there loss or qualitative changes in the expression of thyroid peroxidase protein in thyroid epithelial cancer?

Czarnocka B, Pastuszko D, Janota-Bzowski M, Weetman AP, Watson PF, Kemp EH, McIntosh RS, Asghar MS, Jarzab B, Gubala E, Wloch J, Lange D.

Br J Cancer. 2001 Sep 14;85(6):875-80.

25.

Comparative mapping of cloned human and murine antithyroglobulin antibodies: recognition by human antibodies of an immunodominant region.

Estienne V, McIntosh RS, Ruf J, Asghar MS, Watson PF, Carayon P, Weetman AP.

Thyroid. 1998 Aug;8(8):643-6.

PMID:
9737357
26.

Analysis of the T-cell receptor Valpha repertoire and cytokine gene expression in Sjögren's syndrome.

Ajjan RA, McIntosh RS, Waterman EA, Watson PF, Franklin CD, Yeoman CM, Weetman AP.

Br J Rheumatol. 1998 Feb;37(2):179-85.

PMID:
9569073
27.

Detection of CD40 on human thyroid follicular cells: analysis of expression and function.

Metcalfe RA, McIntosh RS, Marelli-Berg F, Lombardi G, Lechler R, Weetman AP.

J Clin Endocrinol Metab. 1998 Apr;83(4):1268-74.

PMID:
9543155
28.

Relationship between autoantibody epitopic recognition and immunoglobulin gene usage.

Guo J, Mcintosh RS, Czarnocka B, Weetman AP, Rapoport B, McLachlan SM.

Clin Exp Immunol. 1998 Feb;111(2):408-14.

29.

Analysis of immunoglobulin G kappa antithyroid peroxidase antibodies from different tissues in Hashimoto's thyroiditis.

McIntosh RS, Asghar MS, Kemp EH, Watson PF, Gardas A, Banga JP, Weetman AP.

J Clin Endocrinol Metab. 1997 Nov;82(11):3818-25.

PMID:
9360547
30.

Immunoglobulin G kappa antithyroid peroxidase antibodies in Hashimoto's thyroiditis: epitope-mapping analysis.

Czarnocka B, Janota-Bzowski M, McIntosh RS, Asghar MS, Watson PF, Kemp EH, Carayon P, Weetman AP.

J Clin Endocrinol Metab. 1997 Aug;82(8):2639-44.

PMID:
9253347
31.

Molecular analysis of the antibody response to thyroglobulin and thyroid peroxidase.

McIntosh RS, Weetman AP.

Thyroid. 1997 Jun;7(3):471-87. Review.

PMID:
9226221
32.

The antibody response in human autoimmune thyroid disease.

McIntosh RS, Asghar MS, Weetman AP.

Clin Sci (Lond). 1997 Jun;92(6):529-41. Review.

PMID:
9205412
34.

Intrathyroidal cytokine gene expression in Hashimoto's thyroiditis.

Ajjan RA, Watson PF, McIntosh RS, Weetman AP.

Clin Exp Immunol. 1996 Sep;105(3):523-8.

36.
37.

Lack of association between a polymorphism in the coding region of the thyrotropin receptor gene and Graves' disease.

Watson PF, French A, Pickerill AP, McIntosh RS, Weetman AP.

J Clin Endocrinol Metab. 1995 Mar;80(3):1032-5.

PMID:
7883818
38.

Cloning and analysis of IgM anti-thyroglobulin autoantibodies from patients with Hashimoto's thyroiditis.

McIntosh RS, Tandon N, Metcalfe RA, Weetman AP.

Biochim Biophys Acta. 1994 Nov 29;1227(3):171-6.

PMID:
7986824
39.

T cell responses to orbital antigens in thyroid-associated ophthalmopathy.

Arnold K, Tandon N, McIntosh RS, Elisei R, Ludgate M, Weetman AP.

Clin Exp Immunol. 1994 May;96(2):329-34.

40.

The gamma delta T cell repertoire in Graves' disease and multinodular goitre.

McIntosh RS, Tandon N, Pickerill AP, Davies R, Barnett D, Weetman AP.

Clin Exp Immunol. 1993 Dec;94(3):473-7.

41.

IL-2 receptor-positive intrathyroidal lymphocytes in Graves' disease. Analysis of V alpha transcript microheterogeneity.

McIntosh RS, Tandon N, Pickerill AP, Davies R, Barnett D, Weetman AP.

J Immunol. 1993 Oct 1;151(7):3884-93.

PMID:
8376808
42.

Use of Epstein-Barr virus-based vectors for expression of thyroid auto-antigens in human B-lymphoblastoid cell lines.

McIntosh RS, Mulcahy AF, Hales JM, Diamond AG.

J Autoimmun. 1993 Jun;6(3):353-65.

PMID:
8397716
43.

No restriction of intrathyroidal T cell receptor V alpha families in the thyroid of Graves' disease.

McIntosh RS, Watson PF, Pickerill AP, Davies R, Weetman AP.

Clin Exp Immunol. 1993 Jan;91(1):147-52.

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