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Items: 39

1.

A heat-stable microparticle platform for oral micronutrient delivery.

Anselmo AC, Xu X, Buerkli S, Zeng Y, Tang W, McHugh KJ, Behrens AM, Rosenberg E, Duan AR, Sugarman JL, Zhuang J, Collins J, Lu X, Graf T, Tzeng SY, Rose S, Acolatse S, Nguyen TD, Le X, Guerra AS, Freed LE, Weinstock SB, Sears CB, Nikolic B, Wood L, Welkhoff PA, Oxley JD, Moretti D, Zimmermann MB, Langer R, Jaklenec A.

Sci Transl Med. 2019 Nov 13;11(518). pii: eaaw3680. doi: 10.1126/scitranslmed.aaw3680.

PMID:
31723037
2.

IL-22-binding protein exacerbates influenza, bacterial super-infection.

Abood RN, McHugh KJ, Rich HE, Ortiz MA, Tobin JM, Ramanan K, Robinson KM, Bomberger JM, Kolls JK, Manni ML, Pociask DA, Alcorn JF.

Mucosal Immunol. 2019 Sep;12(5):1231-1243. doi: 10.1038/s41385-019-0188-7. Epub 2019 Jul 11.

PMID:
31296910
3.

Computational modeling of retinal hypoxia and photoreceptor degeneration in patients with age-related macular degeneration.

McHugh KJ, Li D, Wang JC, Kwark L, Loo J, Macha V, Farsiu S, Kim LA, Saint-Geniez M.

PLoS One. 2019 Jun 11;14(6):e0216215. doi: 10.1371/journal.pone.0216215. eCollection 2019.

4.

Peroxisome Proliferator-Activated Receptor Gamma (PPAR) Suppresses Inflammation and Bacterial Clearance during Influenza-Bacterial Super-Infection.

Gopal R, Mendy A, Marinelli MA, Richwalls LJ, Seger PJ, Patel S, McHugh KJ, Rich HE, Grousd JA, Forno E, Alcorn JF.

Viruses. 2019 Jun 1;11(6). pii: E505. doi: 10.3390/v11060505.

5.

Interferon Lambda Inhibits Bacterial Uptake during Influenza Superinfection.

Rich HE, McCourt CC, Zheng WQ, McHugh KJ, Robinson KM, Wang J, Alcorn JF.

Infect Immun. 2019 Apr 23;87(5). pii: e00114-19. doi: 10.1128/IAI.00114-19. Print 2019 Mar.

6.

STAT2 Signaling Regulates Macrophage Phenotype During Influenza and Bacterial Super-Infection.

Gopal R, Lee B, McHugh KJ, Rich HE, Ramanan K, Mandalapu S, Clay ME, Seger PJ, Enelow RI, Manni ML, Robinson KM, Rangel-Moreno J, Alcorn JF.

Front Immunol. 2018 Sep 25;9:2151. doi: 10.3389/fimmu.2018.02151. eCollection 2018.

7.

Stabilized single-injection inactivated polio vaccine elicits a strong neutralizing immune response.

Tzeng SY, McHugh KJ, Behrens AM, Rose S, Sugarman JL, Ferber S, Langer R, Jaklenec A.

Proc Natl Acad Sci U S A. 2018 Jun 5;115(23):E5269-E5278. doi: 10.1073/pnas.1720970115. Epub 2018 May 21.

8.

Evaporative Cooling Hydrogel Packaging for Storing Biologics Outside of the Cold Chain.

Ferber S, Behrens AM, McHugh KJ, Rosenberg EM, Linehan AR, Sugarman JL, Jayawardena HSN, Langer R, Jaklenec A.

Adv Healthc Mater. 2018 Jul;7(14):e1800220. doi: 10.1002/adhm.201800220. Epub 2018 May 7.

PMID:
29732715
9.

The inflammasome potentiates influenza/Staphylococcus aureus superinfection in mice.

Robinson KM, Ramanan K, Clay ME, McHugh KJ, Pilewski MJ, Nickolich KL, Corey C, Shiva S, Wang J, Muzumdar R, Alcorn JF.

JCI Insight. 2018 Apr 5;3(7). pii: 97470. doi: 10.1172/jci.insight.97470. eCollection 2018 Apr 5.

10.

STAT1 Is Required for Suppression of Type 17 Immunity during Influenza and Bacterial Superinfection.

Lee B, Gopal R, Manni ML, McHugh KJ, Mandalapu S, Robinson KM, Alcorn JF.

Immunohorizons. 2017 Aug 1;1(6):81-91. doi: 10.4049/immunohorizons.1700030.

11.

Biocompatible Semiconductor Quantum Dots as Cancer Imaging Agents.

McHugh KJ, Jing L, Behrens AM, Jayawardena S, Tang W, Gao M, Langer R, Jaklenec A.

Adv Mater. 2018 May;30(18):e1706356. doi: 10.1002/adma.201706356. Epub 2018 Feb 22. Review.

PMID:
29468747
12.

Increased mortality from influenza infection in long-chain acyl-CoA dehydrogenase knockout mice.

Shinde A, Luo J, Bharathi SS, Shi H, Beck ME, McHugh KJ, Alcorn JF, Wang J, Goetzman ES.

Biochem Biophys Res Commun. 2018 Mar 4;497(2):700-704. doi: 10.1016/j.bbrc.2018.02.135. Epub 2018 Feb 16.

13.

Fabrication of fillable microparticles and other complex 3D microstructures.

McHugh KJ, Nguyen TD, Linehan AR, Yang D, Behrens AM, Rose S, Tochka ZL, Tzeng SY, Norman JJ, Anselmo AC, Xu X, Tomasic S, Taylor MA, Lu J, Guarecuco R, Langer R, Jaklenec A.

Science. 2017 Sep 15;357(6356):1138-1142. doi: 10.1126/science.aaf7447.

14.

Immunogenicity of pulsatile-release PLGA microspheres for single-injection vaccination.

Guarecuco R, Lu J, McHugh KJ, Norman JJ, Thapa LS, Lydon E, Langer R, Jaklenec A.

Vaccine. 2018 May 24;36(22):3161-3168. doi: 10.1016/j.vaccine.2017.05.094. Epub 2017 Jun 19.

15.

Identification of a synergistic interaction between endothelial cells and retinal pigment epithelium.

Spencer C, Abend S, McHugh KJ, Saint-Geniez M.

J Cell Mol Med. 2017 Oct;21(10):2542-2552. doi: 10.1111/jcmm.13175. Epub 2017 Apr 12.

16.

Novel protective mechanism for interleukin-33 at the mucosal barrier during influenza-associated bacterial superinfection.

Robinson KM, Ramanan K, Clay ME, McHugh KJ, Rich HE, Alcorn JF.

Mucosal Immunol. 2018 Jan;11(1):199-208. doi: 10.1038/mi.2017.32. Epub 2017 Apr 12.

17.

Epigenetic and Transcriptomic Regulation of Lung Repair during Recovery from Influenza Infection.

Pociask DA, Robinson KM, Chen K, McHugh KJ, Clay ME, Huang GT, Benos PV, Janssen-Heininger YMW, Kolls JK, Anathy V, Alcorn JF.

Am J Pathol. 2017 Apr;187(4):851-863. doi: 10.1016/j.ajpath.2016.12.012. Epub 2017 Feb 10.

18.

Parasite diversity of African longfin eel Anguilla mossambica Peters with comments on host response to the monogenean Pseudodactylogyrus anguillae (Yin and Sproston).

McHugh KJ, Weyl OLF, Smit NJ.

J Fish Dis. 2017 Jul;40(7):959-961. doi: 10.1111/jfd.12560. Epub 2016 Oct 10. No abstract available.

PMID:
27723106
19.

Layer-by-Layer Encapsulation of Probiotics for Delivery to the Microbiome.

Anselmo AC, McHugh KJ, Webster J, Langer R, Jaklenec A.

Adv Mater. 2016 Nov;28(43):9486-9490. doi: 10.1002/adma.201603270. Epub 2016 Sep 12.

20.

Thermostabilization of inactivated polio vaccine in PLGA-based microspheres for pulsatile release.

Tzeng SY, Guarecuco R, McHugh KJ, Rose S, Rosenberg EM, Zeng Y, Langer R, Jaklenec A.

J Control Release. 2016 Jul 10;233:101-13. doi: 10.1016/j.jconrel.2016.05.012. Epub 2016 May 11.

21.

A Novel CD4+ T Cell-Dependent Murine Model of Pneumocystis-driven Asthma-like Pathology.

Eddens T, Campfield BT, Serody K, Manni ML, Horne W, Elsegeiny W, McHugh KJ, Pociask D, Chen K, Zheng M, Alcorn JF, Wenzel S, Kolls JK.

Am J Respir Crit Care Med. 2016 Oct 1;194(7):807-820.

22.

Molecular Mechanisms of Airway Hyperresponsiveness in a Murine Model of Steroid-Resistant Airway Inflammation.

Manni ML, Mandalapu S, McHugh KJ, Elloso MM, Dudas PL, Alcorn JF.

J Immunol. 2016 Feb 1;196(3):963-77. doi: 10.4049/jimmunol.1501531. Epub 2016 Jan 4.

23.

Looking Beyond Respiratory Cultures: Microbiome-Cytokine Signatures of Bacterial Pneumonia and Tracheobronchitis in Lung Transplant Recipients.

Shankar J, Nguyen MH, Crespo MM, Kwak EJ, Lucas SK, McHugh KJ, Mounaud S, Alcorn JF, Pilewski JM, Shigemura N, Kolls JK, Nierman WC, Clancy CJ.

Am J Transplant. 2016 Jun;16(6):1766-78. doi: 10.1111/ajt.13676. Epub 2016 Feb 10.

24.

Single-injection vaccines: Progress, challenges, and opportunities.

McHugh KJ, Guarecuco R, Langer R, Jaklenec A.

J Control Release. 2015 Dec 10;219:596-609. doi: 10.1016/j.jconrel.2015.07.029. Epub 2015 Aug 4.

PMID:
26254198
25.

Influenza-induced type I interferon enhances susceptibility to gram-negative and gram-positive bacterial pneumonia in mice.

Lee B, Robinson KM, McHugh KJ, Scheller EV, Mandalapu S, Chen C, Di YP, Clay ME, Enelow RI, Dubin PJ, Alcorn JF.

Am J Physiol Lung Cell Mol Physiol. 2015 Jul 15;309(2):L158-67. doi: 10.1152/ajplung.00338.2014. Epub 2015 May 22.

26.

Long-chain acyl-CoA dehydrogenase deficiency as a cause of pulmonary surfactant dysfunction.

Goetzman ES, Alcorn JF, Bharathi SS, Uppala R, McHugh KJ, Kosmider B, Chen R, Zuo YY, Beck ME, McKinney RW, Skilling H, Suhrie KR, Karunanidhi A, Yeasted R, Otsubo C, Ellis B, Tyurina YY, Kagan VE, Mallampalli RK, Vockley J.

J Biol Chem. 2014 Apr 11;289(15):10668-79. doi: 10.1074/jbc.M113.540260. Epub 2014 Mar 3.

27.

Porous poly(ε-caprolactone) scaffolds for retinal pigment epithelium transplantation.

McHugh KJ, Tao SL, Saint-Geniez M.

Invest Ophthalmol Vis Sci. 2014 Mar 25;55(3):1754-62. doi: 10.1167/iovs.13-12833.

28.

A novel outbred mouse model of 2009 pandemic influenza and bacterial co-infection severity.

McHugh KJ, Mandalapu S, Kolls JK, Ross TM, Alcorn JF.

PLoS One. 2013 Dec 6;8(12):e82865. doi: 10.1371/journal.pone.0082865. eCollection 2013.

29.

Influenza A exacerbates Staphylococcus aureus pneumonia by attenuating IL-1β production in mice.

Robinson KM, Choi SM, McHugh KJ, Mandalapu S, Enelow RI, Kolls JK, Alcorn JF.

J Immunol. 2013 Nov 15;191(10):5153-9. doi: 10.4049/jimmunol.1301237. Epub 2013 Oct 2.

30.

Influenza A virus exacerbates Staphylococcus aureus pneumonia in mice by attenuating antimicrobial peptide production.

Robinson KM, McHugh KJ, Mandalapu S, Clay ME, Lee B, Scheller EV, Enelow RI, Chan YR, Kolls JK, Alcorn JF.

J Infect Dis. 2014 Mar;209(6):865-75. doi: 10.1093/infdis/jit527. Epub 2013 Sep 26.

31.

Topographical control of ocular cell types for tissue engineering.

McHugh KJ, Saint-Geniez M, Tao SL.

J Biomed Mater Res B Appl Biomater. 2013 Nov;101(8):1571-84. doi: 10.1002/jbm.b.32968. Epub 2013 Jun 7. Review.

32.

A novel porous scaffold fabrication technique for epithelial and endothelial tissue engineering.

McHugh KJ, Tao SL, Saint-Geniez M.

J Mater Sci Mater Med. 2013 Jul;24(7):1659-70. doi: 10.1007/s10856-013-4934-1. Epub 2013 Apr 27.

33.

First report of nephrocalcinosis in a wild population of Mugil cephalus L. and Myxus capensis (Valenciennes).

McHugh KJ, Van Dyk JC, Weyl OL, Smit NJ.

J Fish Dis. 2013 Oct;36(10):887-9. doi: 10.1111/jfd.12101. Epub 2013 Mar 18. No abstract available.

PMID:
23496659
34.

IL-22 is essential for lung epithelial repair following influenza infection.

Pociask DA, Scheller EV, Mandalapu S, McHugh KJ, Enelow RI, Fattman CL, Kolls JK, Alcorn JF.

Am J Pathol. 2013 Apr;182(4):1286-96. doi: 10.1016/j.ajpath.2012.12.007. Epub 2013 Mar 11.

35.

Translocator protein blockade reduces prostate tumor growth.

Fafalios A, Akhavan A, Parwani AV, Bies RR, McHugh KJ, Pflug BR.

Clin Cancer Res. 2009 Oct 1;15(19):6177-84. doi: 10.1158/1078-0432.CCR-09-0844. Epub 2009 Sep 29.

36.

The law of unintended consequences: The Joint Commission regulations and the digital rectal examination.

Adams BD, McHugh KJ, Bryson SA, Dabulewicz J.

Ann Emerg Med. 2008 Feb;51(2):197-201, 201.e1. Epub 2007 Oct 25.

PMID:
17961818
37.

Exudative and absorptive permeability in different phases of an experimental colitis condition.

McHugh KJ, Svensjö E, Persson CG.

Scand J Gastroenterol. 1996 Sep;31(9):900-5.

PMID:
8888438
38.

Central interleukin-1 receptors contribute to suppression of feeding after acute colitis in the rat.

McHugh KJ, Collins SM, Weingarten HP.

Am J Physiol. 1994 May;266(5 Pt 2):R1659-63.

PMID:
8203647
39.

On the suppression of food intake in experimental models of colitis in the rat.

McHugh KJ, Weingarten HP, Keenan C, Wallace JL, Collins SM.

Am J Physiol. 1993 May;264(5 Pt 2):R871-6.

PMID:
8498596

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