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Items: 1 to 50 of 148


Impact of FcγR variants on the response to alemtuzumab in multiple sclerosis.

Keller CW, Ruck T, McHugh D, Pfeuffer S, Gross CC, Korsukewitz C, Melzer N, Klotz L, Meuth SG, Münz C, Nimmerjahn F, Wiendl H, Lünemann JD.

Ann Clin Transl Neurol. 2019 Nov 4. doi: 10.1002/acn3.50935. [Epub ahead of print]


Lysosomotropic-related limitations of the BALB/c 3T3 cell-based neutral red uptake assay and an alternative testing approach for assessing e-liquid cytotoxicity.

Cudazzo G, Smart DJ, McHugh D, Vanscheeuwijck P.

Toxicol In Vitro. 2019 Dec;61:104647. doi: 10.1016/j.tiv.2019.104647. Epub 2019 Sep 10.


A BAC Transgene Expressing Human CFTR under Control of Its Regulatory Elements Rescues Cftr Knockout Mice.

Gawenis LR, Hodges CA, McHugh DR, Valerio DM, Miron A, Cotton CU, Liu J, Walker NM, Strubberg AM, Gillen AE, Mutolo MJ, Kotzamanis G, Bosch J, Harris A, Drumm ML, Clarke LL.

Sci Rep. 2019 Aug 14;9(1):11828. doi: 10.1038/s41598-019-48105-4.


Mode-of-action analysis of the effects induced by nicotine in the in vitro micronucleus assay.

Smart DJ, Helbling FR, Verardo M, McHugh D, Vanscheeuwijck P.

Environ Mol Mutagen. 2019 Dec;60(9):778-791. doi: 10.1002/em.22314. Epub 2019 Aug 30.


Assessing diagnostic error in cerebral venous thrombosis via detailed chart review.

Liberman AL, Bakradze E, Mchugh DC, Esenwa CC, Lipton RB.

Diagnosis (Berl). 2019 Nov 26;6(4):361-367. doi: 10.1515/dx-2019-0003.


Habitat and introduced predators influence the occupancy of small threatened macropods in subtropical Australia.

McHugh D, Goldingay RL, Link J, Letnic M.

Ecol Evol. 2019 Apr 29;9(11):6300-6317. doi: 10.1002/ece3.5203. eCollection 2019 Jun.


Extracellular resistance is sensitive to tissue sodium status; implications for bioimpedance-derived fluid volume parameters in chronic kidney disease.

Mitsides N, McHugh D, Swiecicka A, Mitra R, Brenchley P, Parker GJM, Mitra S.

J Nephrol. 2019 Jun 18. doi: 10.1007/s40620-019-00620-3. [Epub ahead of print]


Co-electrospraying of tumour cell mimicking hollow polymeric microspheres for diffusion magnetic resonance imaging.

Zhou FL, Wu H, McHugh DJ, Wimpenny I, Zhang X, Gough JE, Hubbard Cristinacce PL, Parker GJM.

Mater Sci Eng C Mater Biol Appl. 2019 Aug;101:217-227. doi: 10.1016/j.msec.2019.03.062. Epub 2019 Mar 19.


Evidence for a GPR18 Role in Chemotaxis, Proliferation, and the Course of Wound Closure in the Cornea.

Murataeva N, Daily L, Taylor X, Dhopeshwarkar A, Hu SS, Miller S, McHugh D, Oehler O, Li S, Bonanno JA, Mackie K, Straiker A.

Cornea. 2019 Jul;38(7):905-913. doi: 10.1097/ICO.0000000000001934.


Infection and immune control of human oncogenic γ-herpesviruses in humanized mice.

McHugh D, Caduff N, Murer A, Engelmann C, Deng Y, Zdimerova H, Zens K, Chijioke O, Münz C.

Philos Trans R Soc Lond B Biol Sci. 2019 May 27;374(1773):20180296. doi: 10.1098/rstb.2018.0296.


Measuring tissue sodium concentration: Cross-vendor repeatability and reproducibility of 23 Na-MRI across two sites.

Riemer F, McHugh D, Zaccagna F, Lewis D, McLean MA, Graves MJ, Gilbert FJ, Parker GJM, Gallagher FA.

J Magn Reson Imaging. 2019 Oct;50(4):1278-1284. doi: 10.1002/jmri.26705. Epub 2019 Mar 12.


A phase I study of the antibody drug conjugate ASG-5ME, an SLC44A4-targeting antibody carrying auristatin E, in metastatic castration-resistant prostate cancer.

McHugh D, Eisenberger M, Heath EI, Bruce J, Danila DC, Rathkopf DE, Feldman J, Slovin SF, Anand B, Chu R, Lackey J, Reyno L, Antonarakis ES, Morris MJ.

Invest New Drugs. 2019 Oct;37(5):1052-1060. doi: 10.1007/s10637-019-00731-5. Epub 2019 Feb 6.


Twelve tips for developing and implementing curriculum in dedicated 'collaborative classrooms'.

McHugh D, Hall JM, McLeod KM, Kovelowski CJ, Payne AM.

Med Teach. 2019 Jan 20:1-6. doi: 10.1080/0142159X.2018.1551992. [Epub ahead of print]


Bifrontal Biparietal Cruciate Decompressive Craniectomy in Pediatric Traumatic Brain Injury.

McHugh DC, Fiore SM, Strong N, Egnor MR.

Pediatr Neurosurg. 2019;54(1):6-11. doi: 10.1159/000495067. Epub 2019 Jan 3.


Towards a 'resolution limit' for DW-MRI tumor microstructural models: A simulation study investigating the feasibility of distinguishing between microstructural changes.

McHugh DJ, Hubbard Cristinacce PL, Naish JH, Parker GJM.

Magn Reson Med. 2019 Apr;81(4):2288-2301. doi: 10.1002/mrm.27551. Epub 2018 Oct 19.


Management of Biochemically Recurrent Prostate Cancer: Ensuring the Right Treatment of the Right Patient at the Right Time.

Spratt DE, McHugh DJ, Morris MJ, Morgans AK.

Am Soc Clin Oncol Educ Book. 2018 May 23;38:355-362. doi: 10.1200/EDBK_200319. Review.


Linaclotide improves gastrointestinal transit in cystic fibrosis mice by inhibiting sodium/hydrogen exchanger 3.

McHugh DR, Cotton CU, Moss FJ, Vitko M, Valerio DM, Kelley TJ, Hao S, Jafri A, Drumm ML, Boron WF, Stern RC, McBennett K, Hodges CA.

Am J Physiol Gastrointest Liver Physiol. 2018 Nov 1;315(5):G868-G878. doi: 10.1152/ajpgi.00261.2017. Epub 2018 Aug 17.


Steric interference from intrinsically disordered regions controls dynamin-related protein 1 self-assembly during mitochondrial fission.

Lu B, Kennedy B, Clinton RW, Wang EJ, McHugh D, Stepanyants N, Macdonald PJ, Mears JA, Qi X, Ramachandran R.

Sci Rep. 2018 Jul 18;8(1):10879. doi: 10.1038/s41598-018-29001-9.


Common Features of Regulatory T Cell Specialization During Th1 Responses.

Littringer K, Moresi C, Rakebrandt N, Zhou X, Schorer M, Dolowschiak T, Kirchner F, Rost F, Keller CW, McHugh D, LeibundGut-Landmann S, Robinson MD, Joller N.

Front Immunol. 2018 Jun 13;9:1344. doi: 10.3389/fimmu.2018.01344. eCollection 2018.


A G542X cystic fibrosis mouse model for examining nonsense mutation directed therapies.

McHugh DR, Steele MS, Valerio DM, Miron A, Mann RJ, LePage DF, Conlon RA, Cotton CU, Drumm ML, Hodges CA.

PLoS One. 2018 Jun 20;13(6):e0199573. doi: 10.1371/journal.pone.0199573. eCollection 2018.


Mapping Hypoxia in Renal Carcinoma with Oxygen-enhanced MRI: Comparison with Intrinsic Susceptibility MRI and Pathology.

Little RA, Jamin Y, Boult JKR, Naish JH, Watson Y, Cheung S, Holliday KF, Lu H, McHugh DJ, Irlam J, West CML, Betts GN, Ashton G, Reynolds AR, Maddineni S, Clarke NW, Parker GJM, Waterton JC, Robinson SP, O'Connor JPB.

Radiology. 2018 Sep;288(3):739-747. doi: 10.1148/radiol.2018171531. Epub 2018 Jun 5.


Microstructural imaging of the human brain with a 'super-scanner': 10 key advantages of ultra-strong gradients for diffusion MRI.

Jones DK, Alexander DC, Bowtell R, Cercignani M, Dell'Acqua F, McHugh DJ, Miller KL, Palombo M, Parker GJM, Rudrapatna US, Tax CMW.

Neuroimage. 2018 Nov 15;182:8-38. doi: 10.1016/j.neuroimage.2018.05.047. Epub 2018 May 22. Review.


Conventional-Dose versus High-Dose Chemotherapy for Relapsed Germ Cell Tumors.

McHugh DJ, Feldman DR.

Adv Urol. 2018 Mar 15;2018:7272541. doi: 10.1155/2018/7272541. eCollection 2018. Review.


EBV persistence without its EBNA3A and 3C oncogenes in vivo.

Murer A, McHugh D, Caduff N, Kalchschmidt J, Barros M, Zbinden A, Capaul R, Niedobitek G, Allday M, Chijioke O, Münz C.

PLoS Pathog. 2018 Apr 30;14(4):e1007039. doi: 10.1371/journal.ppat.1007039. eCollection 2018 Apr.


Androgen-deprivation therapy, dementia, and cognitive dysfunction in men with prostate cancer: How much smoke and how much fire?

McHugh DJ, Root JC, Nelson CJ, Morris MJ.

Cancer. 2018 Apr 1;124(7):1326-1334. doi: 10.1002/cncr.31153. Epub 2018 Jan 16. Review.


Vitrectomy with fibrovascular membrane delamination for proliferative diabetic retinopathy with or without preoperative Avastin.

Papavasileiou E, Vasalaki M, Garnavou-Xirou C, Velissaris S, Zygoura V, McHugh D, Jackson TL.

Hell J Nucl Med. 2017 Sep-Dec;20 Suppl:161.


Review article: Idle 'just-in-case' peripheral intravenous cannulas in the emergency department: Is something wrong?

Gledstone-Brown L, McHugh D.

Emerg Med Australas. 2018 Jun;30(3):309-326. doi: 10.1111/1742-6723.12877. Epub 2017 Dec 6. Review.


A Systematic Review of the Efficacy of Levetiracetam in Neonatal Seizures.

McHugh DC, Lancaster S, Manganas LN.

Neuropediatrics. 2018 Feb;49(1):12-17. doi: 10.1055/s-0037-1608653. Epub 2017 Nov 27. Review.


A biomimetic tumor tissue phantom for validating diffusion-weighted MRI measurements.

McHugh DJ, Zhou FL, Wimpenny I, Poologasundarampillai G, Naish JH, Hubbard Cristinacce PL, Parker GJM.

Magn Reson Med. 2018 Jul;80(1):147-158. doi: 10.1002/mrm.27016. Epub 2017 Nov 20.


Humanised mouse models for haematopoiesis and infectious diseases.

Lysenko V, McHugh D, Behrmann L, Rochat MA, Wilk CM, Kovtonyuk L, Bourquin JP, Münz C, Manz MG, Speck R, Theocharides A.

Swiss Med Wkly. 2017 Oct 22;147:w14516. doi: 10.4414/smw.2017.14516. eCollection 2017. Review.


Senescence and aging: Causes, consequences, and therapeutic avenues.

McHugh D, Gil J.

J Cell Biol. 2018 Jan 2;217(1):65-77. doi: 10.1083/jcb.201708092. Epub 2017 Nov 7. Review.


Intravitreal gas for symptomatic vitreomacular adhesion: a synthesis of the literature.

Neffendorf JE, Simpson ARH, Steel DHW, Desai R, McHugh DA, Pringle E, Jackson TL.

Acta Ophthalmol. 2018 Nov;96(7):685-691. doi: 10.1111/aos.13547. Epub 2017 Aug 31. Review.


Persistent KSHV Infection Increases EBV-Associated Tumor Formation In Vivo via Enhanced EBV Lytic Gene Expression.

McHugh D, Caduff N, Barros MHM, Rämer PC, Raykova A, Murer A, Landtwing V, Quast I, Styles CT, Spohn M, Fowotade A, Delecluse HJ, Papoudou-Bai A, Lee YM, Kim JM, Middeldorp J, Schulz TF, Cesarman E, Zbinden A, Capaul R, White RE, Allday MJ, Niedobitek G, Blackbourn DJ, Grundhoff A, Münz C.

Cell Host Microbe. 2017 Jul 12;22(1):61-73.e7. doi: 10.1016/j.chom.2017.06.009.


Hemostasis in endoscopic endonasal skull base surgery using the Aquamantys bipolar sealer: Technical note.

Bram R, Fiore S, McHugh D, Samara GJ, Davis RP.

J Clin Neurosci. 2017 Jul;41:81-85. doi: 10.1016/j.jocn.2017.02.061. Epub 2017 Mar 9.


Gas Tamponade for Retinectomy in PVR-Related Retinal Detachments: A Retrospective Study.

Papastavrou VT, Chatziralli I, McHugh D.

Ophthalmol Ther. 2017 Jun;6(1):161-166. doi: 10.1007/s40123-017-0078-6. Epub 2017 Feb 3.


Evaluation of the Tobacco Heating System 2.2. Part 2: Chemical composition, genotoxicity, cytotoxicity, and physical properties of the aerosol.

Schaller JP, Keller D, Poget L, Pratte P, Kaelin E, McHugh D, Cudazzo G, Smart D, Tricker AR, Gautier L, Yerly M, Reis Pires R, Le Bouhellec S, Ghosh D, Hofer I, Garcia E, Vanscheeuwijck P, Maeder S.

Regul Toxicol Pharmacol. 2016 Nov 30;81 Suppl 2:S27-S47. doi: 10.1016/j.yrtph.2016.10.001. Epub 2016 Oct 6.


Genome Sequences of Newly Isolated Mycobacteriophages Forming Cluster S.

Mills ML, Bragg J, Bruce A, Dehn A, Drouin J, Hefner M, Katon D, McHugh D, Zeba F, Bowman CA, Cresawn SG, Jacobs-Sera D, Russell DA, Pope WH, Hatfull GF, Dunbar DA, Zegers GP, Page ST.

Genome Announc. 2016 Sep 29;4(5). pii: e00933-16. doi: 10.1128/genomeA.00933-16.


ATRX binds to atypical chromatin domains at the 3' exons of zinc finger genes to preserve H3K9me3 enrichment.

Valle-García D, Qadeer ZA, McHugh DS, Ghiraldini FG, Chowdhury AH, Hasson D, Dyer MA, Recillas-Targa F, Bernstein E.

Epigenetics. 2016 Jun 2;11(6):398-414. doi: 10.1080/15592294.2016.1169351. Epub 2016 Mar 30.


Ground Truth for Diffusion MRI in Cancer: A Model-Based Investigation of a Novel Tissue-Mimetic Material.

McHugh DJ, Zhou F, Cristinacce PL, Naish JH, Parker GJ.

Inf Process Med Imaging. 2015;24:179-90.


Cannabinoid-induced chemotaxis in bovine corneal epithelial cells.

Murataeva N, Li S, Oehler O, Miller S, Dhopeshwarkar A, Hu SS, Bonanno JA, Bradshaw H, Mackie K, McHugh D, Straiker A.

Invest Ophthalmol Vis Sci. 2015 May;56(5):3304-13. doi: 10.1167/iovs.14-15675.


Endogenous opioid inhibition of proliferation of T and B cell subpopulations in response to immunization for experimental autoimmune encephalomyelitis.

McLaughlin PJ, McHugh DP, Magister MJ, Zagon IS.

BMC Immunol. 2015 Apr 24;16:24. doi: 10.1186/s12865-015-0093-0.


Animal models of Epstein Barr virus infection.

Gujer C, Chatterjee B, Landtwing V, Raykova A, McHugh D, Münz C.

Curr Opin Virol. 2015 Aug;13:6-10. doi: 10.1016/j.coviro.2015.03.014. Epub 2015 Apr 2. Review.


Neurodegeneration and unfolded-protein response in mice expressing a membrane-tethered flexible tail of PrP.

Dametto P, Lakkaraju AK, Bridel C, Villiger L, O'Connor T, Herrmann US, Pelczar P, Rülicke T, McHugh D, Adili A, Aguzzi A.

PLoS One. 2015 Feb 6;10(2):e0117412. doi: 10.1371/journal.pone.0117412. eCollection 2015.


Novel endogenous N-acyl amides activate TRPV1-4 receptors, BV-2 microglia, and are regulated in brain in an acute model of inflammation.

Raboune S, Stuart JM, Leishman E, Takacs SM, Rhodes B, Basnet A, Jameyfield E, McHugh D, Widlanski T, Bradshaw HB.

Front Cell Neurosci. 2014 Aug 1;8:195. doi: 10.3389/fncel.2014.00195. eCollection 2014.


Postanalytical tools improve performance of newborn screening by tandem mass spectrometry.

Hall PL, Marquardt G, McHugh DM, Currier RJ, Tang H, Stoway SD, Rinaldo P.

Genet Med. 2014 Dec;16(12):889-95. doi: 10.1038/gim.2014.62. Epub 2014 May 29.


Δ(9)-THC and N-arachidonoyl glycine regulate BV-2 microglial morphology and cytokine release plasticity: implications for signaling at GPR18.

McHugh D, Roskowski D, Xie S, Bradshaw HB.

Front Pharmacol. 2014 Jan 2;4:162. doi: 10.3389/fphar.2013.00162. eCollection 2014.


Infectious diseases in humanized mice.

Leung C, Chijioke O, Gujer C, Chatterjee B, Antsiferova O, Landtwing V, McHugh D, Raykova A, Münz C.

Eur J Immunol. 2013 Sep;43(9):2246-54. doi: 10.1002/eji.201343815. Review.


Safety testing of epimacular brachytherapy with microperimetry and indocyanine green angiography: 12-month results.

Petrarca R, Richardson M, Douiri A, Nau J, McHugh D, Stangos AN, Jackson TL.

Retina. 2013 Jun;33(6):1232-40. doi: 10.1097/IAE.0b013e3182794b22.


Intravitreal tissue plasminogen activator, perfluoropropane (C3F8), and ranibizumab or photodynamic therapy for submacular hemorrhage secondary to wet age-related macular degeneration.

Papavasileiou E, Steel DH, Liazos E, McHugh D, Jackson TL.

Retina. 2013 Apr;33(4):846-53. doi: 10.1097/IAE.0b013e318271f278.


Intravitreal injection of expansile perfluoropropane (c(3)f(8)) for the treatment of vitreomacular traction.

Rodrigues IA, Stangos AN, McHugh DA, Jackson TL.

Am J Ophthalmol. 2013 Feb;155(2):270-276.e2. doi: 10.1016/j.ajo.2012.08.018. Epub 2012 Nov 17.


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