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Items: 21


Exposure to the antimicrobial peptide LL-37 produces dendritic cells optimized for immunotherapy.

Findlay EG, Currie AJ, Zhang A, Ovciarikova J, Young L, Stevens H, McHugh BJ, Canel M, Gray M, Milling SWF, Campbell JDM, Savill J, Serrels A, Davidson DJ.

Oncoimmunology. 2019 May 1;8(8):1608106. doi: 10.1080/2162402X.2019.1608106. eCollection 2019.


Cathelicidins and the Onset of Labour.

Boeckel SRV, Hrabalkova L, Baker TL, MacPherson H, Frew L, Boyle AK, McHugh BJ, Wilson K, Norman JE, Dorin JR, Davidson DJ, Stock SJ.

Sci Rep. 2019 May 14;9(1):7356. doi: 10.1038/s41598-019-43766-7.


Cathelicidin is a "fire alarm", generating protective NLRP3-dependent airway epithelial cell inflammatory responses during infection with Pseudomonas aeruginosa.

McHugh BJ, Wang R, Li HN, Beaumont PE, Kells R, Stevens H, Young L, Rossi AG, Gray RD, Dorin JR, Gwyer Findlay EL, Brough D, Davidson DJ.

PLoS Pathog. 2019 Apr 12;15(4):e1007694. doi: 10.1371/journal.ppat.1007694. eCollection 2019 Apr.


An Orally Active Galectin-3 Antagonist Inhibits Lung Adenocarcinoma Growth and Augments Response to PD-L1 Blockade.

Vuong L, Kouverianou E, Rooney CM, McHugh BJ, Howie SEM, Gregory CD, Forbes SJ, Henderson NC, Zetterberg FR, Nilsson UJ, Leffler H, Ford P, Pedersen A, Gravelle L, Tantawi S, Schambye H, Sethi T, MacKinnon AC.

Cancer Res. 2019 Apr 1;79(7):1480-1492. doi: 10.1158/0008-5472.CAN-18-2244. Epub 2019 Jan 23.


Blood Neutrophils Are Reprogrammed in Bronchiectasis.

Bedi P, Davidson DJ, McHugh BJ, Rossi AG, Hill AT.

Am J Respir Crit Care Med. 2018 Oct 1;198(7):880-890. doi: 10.1164/rccm.201712-2423OC.


Microbial Host Interactions and Impaired Wound Healing in Mice and Humans: Defining a Role for BD14 and NOD2.

Williams H, Campbell L, Crompton RA, Singh G, McHugh BJ, Davidson DJ, McBain AJ, Cruickshank SM, Hardman MJ.

J Invest Dermatol. 2018 Oct;138(10):2264-2274. doi: 10.1016/j.jid.2018.04.014. Epub 2018 Apr 30.


IL-1β-Induced Protection of Keratinocytes against Staphylococcus aureus-Secreted Proteases Is Mediated by Human β-Defensin 2.

Wang B, McHugh BJ, Qureshi A, Campopiano DJ, Clarke DJ, Fitzgerald JR, Dorin JR, Weller R, Davidson DJ.

J Invest Dermatol. 2017 Jan;137(1):95-105. doi: 10.1016/j.jid.2016.08.025. Epub 2016 Oct 1.


Differential response to bacteria, and TOLLIP expression, in the human respiratory tract.

Moncayo-Nieto OL, Wilkinson TS, Brittan M, McHugh BJ, Jones RO, Conway Morris A, Walker WS, Davidson DJ, Simpson AJ.

BMJ Open Respir Res. 2014 Sep 11;1(1):e000046. doi: 10.1136/bmjresp-2014-000046. eCollection 2014.


Human cathelicidin production by the cervix.

Frew L, Makieva S, McKinlay AT, McHugh BJ, Doust A, Norman JE, Davidson DJ, Stock SJ.

PLoS One. 2014 Aug 4;9(8):e103434. doi: 10.1371/journal.pone.0103434. eCollection 2014.


Intracranial infantile hemangiopericytoma.

McHugh BJ, Baranoski JF, Malhotra A, Vortmeyer AO, Sze G, Duncan CC.

J Neurosurg Pediatr. 2014 Aug;14(2):149-54. doi: 10.3171/2014.4.PEDS13463. Epub 2014 Jun 6.


Surgical treatment for adult spinal deformity: projected cost effectiveness at 5-year follow-up.

Terran J, McHugh BJ, Fischer CR, Lonner B, Warren D, Glassman S, Bridwell K, Schwab F, Lafage V.

Ochsner J. 2014 Spring;14(1):14-22.


Mannose-binding lectin deficiency and disease severity in non-cystic fibrosis bronchiectasis: a prospective study.

Chalmers JD, McHugh BJ, Doherty C, Smith MP, Govan JR, Kilpatrick DC, Hill AT.

Lancet Respir Med. 2013 May;1(3):224-32. doi: 10.1016/S2213-2600(13)70001-8. Epub 2013 Jan 28.


The human cathelicidin LL-37 has antiviral activity against respiratory syncytial virus.

Currie SM, Findlay EG, McHugh BJ, Mackellar A, Man T, Macmillan D, Wang H, Fitch PM, Schwarze J, Davidson DJ.

PLoS One. 2013 Aug 30;8(8):e73659. doi: 10.1371/journal.pone.0073659. eCollection 2013.


Cost analysis of anterior-posterior circumferential fusion and transforaminal lumbar interbody fusion.

Andres TM, Park JJ, Ricart Hoffiz PA, McHugh BJ, Warren DT, Errico TJ.

Spine J. 2013 Jun;13(6):651-6. doi: 10.1016/j.spinee.2012.11.055. Epub 2013 Jan 23.


Vitamin-D deficiency is associated with chronic bacterial colonisation and disease severity in bronchiectasis.

Chalmers JD, McHugh BJ, Docherty C, Govan JR, Hill AT.

Thorax. 2013 Jan;68(1):39-47. doi: 10.1136/thoraxjnl-2012-202125. Epub 2012 Oct 16.


Congenital os odontoideum arising from the secondary ossification center without prior fracture.

McHugh BJ, Grant RA, Zupon AB, DiLuna ML.

J Neurosurg Spine. 2012 Dec;17(6):594-7. doi: 10.3171/2012.9.SPINE12824. Epub 2012 Oct 5.


Loss of the integrin-activating transmembrane protein Fam38A (Piezo1) promotes a switch to a reduced integrin-dependent mode of cell migration.

McHugh BJ, Murdoch A, Haslett C, Sethi T.

PLoS One. 2012;7(7):e40346. doi: 10.1371/journal.pone.0040346. Epub 2012 Jul 5.


Short- and long-term antibiotic treatment reduces airway and systemic inflammation in non-cystic fibrosis bronchiectasis.

Chalmers JD, Smith MP, McHugh BJ, Doherty C, Govan JR, Hill AT.

Am J Respir Crit Care Med. 2012 Oct 1;186(7):657-65. doi: 10.1164/rccm.201203-0487OC. Epub 2012 Jun 28.


A comprehensive review of MR imaging changes following radiosurgery to 500 brain metastases.

Patel TR, McHugh BJ, Bi WL, Minja FJ, Knisely JP, Chiang VL.

AJNR Am J Neuroradiol. 2011 Nov-Dec;32(10):1885-92. doi: 10.3174/ajnr.A2668. Epub 2011 Sep 15. Review.


Integrin activation by Fam38A uses a novel mechanism of R-Ras targeting to the endoplasmic reticulum.

McHugh BJ, Buttery R, Lad Y, Banks S, Haslett C, Sethi T.

J Cell Sci. 2010 Jan 1;123(Pt 1):51-61. doi: 10.1242/jcs.056424.


Mammalian NOTCH-1 activates beta1 integrins via the small GTPase R-Ras.

Hodkinson PS, Elliott PA, Lad Y, McHugh BJ, MacKinnon AC, Haslett C, Sethi T.

J Biol Chem. 2007 Sep 28;282(39):28991-9001. Epub 2007 Jul 30.

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