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Items: 13


C-reactive protein and pentraxin-3 binding of factor H-like protein 1 differs from complement factor H: implications for retinal inflammation.

Swinkels M, Zhang JH, Tilakaratna V, Black G, Perveen R, McHarg S, Inforzato A, Day AJ, Clark SJ.

Sci Rep. 2018 Jan 26;8(1):1643. doi: 10.1038/s41598-017-18395-7.


Bruch's Membrane Compartmentalizes Complement Regulation in the Eye with Implications for Therapeutic Design in Age-Related Macular Degeneration.

Clark SJ, McHarg S, Tilakaratna V, Brace N, Bishop PN.

Front Immunol. 2017 Dec 19;8:1778. doi: 10.3389/fimmu.2017.01778. eCollection 2017.


Elevation of brain glucose and polyol-pathway intermediates with accompanying brain-copper deficiency in patients with Alzheimer's disease: metabolic basis for dementia.

Xu J, Begley P, Church SJ, Patassini S, McHarg S, Kureishy N, Hollywood KA, Waldvogel HJ, Liu H, Zhang S, Lin W, Herholz K, Turner C, Synek BJ, Curtis MA, Rivers-Auty J, Lawrence CB, Kellett KA, Hooper NM, Vardy ER, Wu D, Unwin RD, Faull RL, Dowsey AW, Cooper GJ.

Sci Rep. 2016 Jun 9;6:27524. doi: 10.1038/srep27524.


Enrichment of Bruch's Membrane from Human Donor Eyes.

McHarg S, Brace N, Bishop PN, Clark SJ.

J Vis Exp. 2015 Nov 15;(105). doi: 10.3791/53382.


Age-related macular degeneration and the role of the complement system.

McHarg S, Clark SJ, Day AJ, Bishop PN.

Mol Immunol. 2015 Sep;67(1):43-50. doi: 10.1016/j.molimm.2015.02.032. Epub 2015 Mar 21. Review.


Deficient copper concentrations in dried-defatted hepatic tissue from ob/ob mice: A potential model for study of defective copper regulation in metabolic liver disease.

Church SJ, Begley P, Kureishy N, McHarg S, Bishop PN, Bechtold DA, Unwin RD, Cooper GJ.

Biochem Biophys Res Commun. 2015 May 8;460(3):549-54. doi: 10.1016/j.bbrc.2015.03.067. Epub 2015 Mar 20.


Down-regulation of desmosomes in cultured cells: the roles of PKC, microtubules and lysosomal/proteasomal degradation.

McHarg S, Hopkins G, Lim L, Garrod D.

PLoS One. 2014 Oct 7;9(10):e108570. doi: 10.1371/journal.pone.0108570. eCollection 2014.


Diabetic cardiomyopathy is associated with defective myocellular copper regulation and both defects are rectified by divalent copper chelation.

Zhang S, Liu H, Amarsingh GV, Cheung CC, Hogl S, Narayanan U, Zhang L, McHarg S, Xu J, Gong D, Kennedy J, Barry B, Choong YS, Phillips AR, Cooper GJ.

Cardiovasc Diabetol. 2014 Jun 14;13:100. doi: 10.1186/1475-2840-13-100.


An improved and reliable method for isolation of microvascular endothelial cells from human omentum.

Winiarski BK, Acheson N, Gutowski NJ, McHarg S, Whatmore JL.

Microcirculation. 2011 Nov;18(8):635-45. doi: 10.1111/j.1549-8719.2011.00128.x.


Desmosomes: adhesive strength and signalling in health and disease.

Thomason HA, Scothern A, McHarg S, Garrod DR.

Biochem J. 2010 Aug 1;429(3):419-33. doi: 10.1042/BJ20100567. Review.


TILRR, a novel IL-1RI co-receptor, potentiates MyD88 recruitment to control Ras-dependent amplification of NF-kappaB.

Zhang X, Shephard F, Kim HB, Palmer IR, McHarg S, Fowler GJ, O'Neill LA, Kiss-Toth E, Qwarnstrom EE.

J Biol Chem. 2010 Mar 5;285(10):7222-32. doi: 10.1074/jbc.M109.073429. Epub 2009 Nov 25. Erratum in: J Biol Chem. 2010 Jun 4;285(23):18122.


Heterogeneity of phospholipase D activation by angiotensin II, lysophosphatidylcholine, and insulin in human endothelial cells.

McHarg S, Shore AC, Whatmore JL.

Endothelium. 2008 Jul-Aug;15(4):213-8. doi: 10.1080/10623320802228765.


Absorption of the cholic acid-conjugated peptide hormone cholylsecretin from the rat ileum in vivo.

McHarg S, Morton JS, McGinn BJ, Yasin M, Morrison JD.

Acta Physiol Scand. 2004 May;181(1):23-34.


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