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Items: 40

1.

DNA polymerase eta participates in the mutagenic bypass of adducts induced by benzo[a]pyrene diol epoxide in mammalian cells.

Klarer AC, Stallons LJ, Burke TJ, Skaggs RL, McGregor WG.

PLoS One. 2012;7(6):e39596. doi: 10.1371/journal.pone.0039596. Epub 2012 Jun 20.

2.

Altered Ig hypermutation pattern and frequency in complementary mouse models of DNA polymerase ΞΆ activity.

Daly J, Bebenek K, Watt DL, Richter K, Jiang C, Zhao ML, Ray M, McGregor WG, Kunkel TA, Diaz M.

J Immunol. 2012 Jun 1;188(11):5528-37. doi: 10.4049/jimmunol.1102629. Epub 2012 Apr 30.

3.

Sequential assembly of translesion DNA polymerases at UV-induced DNA damage sites.

Andersen PL, Xu F, Ziola B, McGregor WG, Xiao W.

Mol Biol Cell. 2011 Jul 1;22(13):2373-83. doi: 10.1091/mbc.E10-12-0938. Epub 2011 May 5.

4.

Translesion synthesis polymerases in the prevention and promotion of carcinogenesis.

Stallons LJ, McGregor WG.

J Nucleic Acids. 2010 Sep 22;2010. pii: 643857. doi: 10.4061/2010/643857.

5.

Micro- and nanotechnology approaches for capturing circulating tumor cells.

Panchapakesan B, Caprara R, Velasco V, Loomis J, King B, Xu P, Burkhead T, Sethu P, Stallons LJ, McGregor WG, Rai SN, Kloecker G, Wickstrom E.

Cancer Nanotechnol. 2010;1(1-6):3-11. Epub 2010 Oct 19. Review.

6.

Effect of rapid human N-acetyltransferase 2 haplotype on DNA damage and mutagenesis induced by 2-amino-3-methylimidazo-[4,5-f]quinoline (IQ) and 2-amino-3,8-dimethylimidazo-[4,5-f]quinoxaline (MeIQx).

Metry KJ, Neale JR, Doll MA, Howarth AL, States JC, McGregor WG, Pierce WM Jr, Hein DW.

Mutat Res. 2010 Feb 3;684(1-2):66-73. doi: 10.1016/j.mrfmmm.2009.12.001. Epub 2009 Dec 11.

7.

REV1 is implicated in the development of carcinogen-induced lung cancer.

Dumstorf CA, Mukhopadhyay S, Krishnan E, Haribabu B, McGregor WG.

Mol Cancer Res. 2009 Feb;7(2):247-54. doi: 10.1158/1541-7786.MCR-08-0399. Epub 2009 Jan 27.

8.

RAD18 and associated proteins are immobilized in nuclear foci in human cells entering S-phase with ultraviolet light-induced damage.

Watson NB, Nelson E, Digman M, Thornburg JA, Alphenaar BW, McGregor WG.

Mutat Res. 2008 Dec 15;648(1-2):23-31. doi: 10.1016/j.mrfmmm.2008.09.006. Epub 2008 Sep 24.

9.

RAD18 signals DNA polymerase IOTA to stalled replication forks in cells entering S-phase with DNA damage.

Kakar S, Watson NB, McGregor WG.

Adv Exp Med Biol. 2008;614:137-43. doi: 10.1007/978-0-387-74911-2_16.

PMID:
18290323
10.

Inhibition of DNA replication fork progression and mutagenic potential of 1, N6-ethenoadenine and 8-oxoguanine in human cell extracts.

Tolentino JH, Burke TJ, Mukhopadhyay S, McGregor WG, Basu AK.

Nucleic Acids Res. 2008 Mar;36(4):1300-8. doi: 10.1093/nar/gkm1157. Epub 2008 Jan 9.

11.

2-amino-1-methyl-6-phenylimidazo [4,5-b] pyridine-induced DNA adducts and genotoxicity in chinese hamster ovary (CHO) cells expressing human CYP1A2 and rapid or slow acetylator N-acetyltransferase 2.

Metry KJ, Zhao S, Neale JR, Doll MA, States JC, McGregor WG, Pierce WM Jr, Hein DW.

Mol Carcinog. 2007 Jul;46(7):553-63. Erratum in: Mol Carcinog. 2007 Sep;46(9):818.

PMID:
17295238
12.

Participation of mouse DNA polymerase iota in strand-biased mutagenic bypass of UV photoproducts and suppression of skin cancer.

Dumstorf CA, Clark AB, Lin Q, Kissling GE, Yuan T, Kucherlapati R, McGregor WG, Kunkel TA.

Proc Natl Acad Sci U S A. 2006 Nov 28;103(48):18083-8. Epub 2006 Nov 17.

13.

Gender difference in the activity but not expression of estrogen receptors alpha and beta in human lung adenocarcinoma cells.

Dougherty SM, Mazhawidza W, Bohn AR, Robinson KA, Mattingly KA, Blankenship KA, Huff MO, McGregor WG, Klinge CM.

Endocr Relat Cancer. 2006 Mar;13(1):113-34.

14.

Cytotoxic and mutagenic effects of tobacco-borne free fatty acids.

Gao X, Qian M, Campian JL, Clark DR, Burke TJ, Eaton JW, McGregor WG.

Free Radic Biol Med. 2006 Jan 1;40(1):165-72. Epub 2005 Oct 17.

PMID:
16337890
15.

Translesion DNA replication proteins as molecular targets for cancer prevention.

Watson NB, Mukhopadhyay S, McGregor WG.

Cancer Lett. 2006 Sep 8;241(1):13-22. Epub 2005 Nov 21. Review.

PMID:
16303242
16.

Telomerase-immortalized human fibroblasts retain UV-induced mutagenesis and p53-mediated DNA damage responses.

Porter PC, Clark DR, McDaniel LD, McGregor WG, States JC.

DNA Repair (Amst). 2006 Jan 5;5(1):61-70. Epub 2005 Sep 1.

PMID:
16140041
17.

REV1 accumulates in DNA damage-induced nuclear foci in human cells and is implicated in mutagenesis by benzo[a]pyrenediolepoxide.

Mukhopadhyay S, Clark DR, Watson NB, Zacharias W, McGregor WG.

Nucleic Acids Res. 2004 Nov 2;32(19):5820-6. Print 2004.

18.
19.

Ribozyme-mediated REV1 inhibition reduces the frequency of UV-induced mutations in the human HPRT gene.

Clark DR, Zacharias W, Panaitescu L, McGregor WG.

Nucleic Acids Res. 2003 Sep 1;31(17):4981-8.

20.

Roles of DNA polymerase zeta and Rev1 protein in eukaryotic mutagenesis and translesion replication.

Lawrence CW, Gibbs PE, Murante RS, Wang XD, Li Z, McManus TP, McGregor WG, Nelson JR, Hinkle DC, Maher VM.

Cold Spring Harb Symp Quant Biol. 2000;65:61-9. Review. No abstract available.

PMID:
12760021
21.

Inhibition of DNA replication and induction of S phase cell cycle arrest by G-rich oligonucleotides.

Xu X, Hamhouyia F, Thomas SD, Burke TJ, Girvan AC, McGregor WG, Trent JO, Miller DM, Bates PJ.

J Biol Chem. 2001 Nov 16;276(46):43221-30. Epub 2001 Sep 12.

22.

2nd Annual Midwest DNA Repair Symposium, University of Louisville, Louisville, KY 20-21 May 2000.

States JC, McGregor WG, Ljungman M.

Mutat Res. 2000 Oct 16;461(2):163-7. No abstract available.

PMID:
11188758
23.

The function of the human homolog of Saccharomyces cerevisiae REV1 is required for mutagenesis induced by UV light.

Gibbs PE, Wang XD, Li Z, McManus TP, McGregor WG, Lawrence CW, Maher VM.

Proc Natl Acad Sci U S A. 2000 Apr 11;97(8):4186-91.

24.

Solution conformation and mutagenic specificity of 1,N6-ethenoadenine.

Basu AK, McNulty JM, McGregor WG.

IARC Sci Publ. 1999;(150):325-33.

PMID:
10626232
25.

DNA repair, DNA replication, and UV mutagenesis.

McGregor WG.

J Investig Dermatol Symp Proc. 1999 Sep;4(1):1-5. Review.

26.

C8-guanine adduct-induced stabilization of a -1 frame shift intermediate in a nonrepetitive DNA sequence.

Nolan SJ, McNulty JM, Krishnasamy R, McGregor WG, Basu AK.

Biochemistry. 1999 Oct 19;38(42):14056-62.

PMID:
10529252
28.

A human homolog of the Saccharomyces cerevisiae REV3 gene, which encodes the catalytic subunit of DNA polymerase zeta.

Gibbs PE, McGregor WG, Maher VM, Nisson P, Lawrence CW.

Proc Natl Acad Sci U S A. 1998 Jun 9;95(12):6876-80.

29.
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35.

Inhibition of mouse retroviral disease by bioactive glutaminase-asparaginase.

Roberts J, McGregor WG.

J Gen Virol. 1991 Feb;72 ( Pt 2):299-305.

PMID:
1704410
36.

Use of PCR amplification of cDNA to study mechanisms of human cell mutagenesis and malignant transformation.

Maher VM, Yang JL, Chen RH, McGregor WG, Lukash L, Scheid JM, Reinhold DS, McCormick JJ.

Environ Mol Mutagen. 1991;18(4):239-44.

PMID:
1748085
37.

Cellular localization of chorionic gonadotropin in human fetal kidney and liver.

Goldsmith PC, McGregor WG, Raymoure WJ, Kuhn RW, Jaffe RB.

J Clin Endocrinol Metab. 1983 Sep;57(3):654-61.

PMID:
6192140
38.

Biologically active chorionic gonadotropin: synthesis by the human fetus.

McGregor WG, Kuhn RW, Jaffe RB.

Science. 1983 Apr 15;220(4594):306-8.

PMID:
6682243
39.
40.

Purification and kinetic characterization of a monovalent cation-activated glycerol dehydrogenase from Aerobacter aerogenes.

McGregor WG, Phillips J, Suelter CH.

J Biol Chem. 1974 May 25;249(10):3132-9. No abstract available.

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