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Items: 15

1.

Mutations of the BCR-ABL-kinase domain occur in a minority of patients with stable complete cytogenetic response to imatinib.

Sherbenou DW, Wong MJ, Humayun A, McGreevey LS, Harrell P, Yang R, Mauro M, Heinrich MC, Press RD, Druker BJ, Deininger MW.

Leukemia. 2007 Mar;21(3):489-93. Epub 2007 Jan 25.

PMID:
17252009
2.

FLT3 K663Q is a novel AML-associated oncogenic kinase: Determination of biochemical properties and sensitivity to Sunitinib (SU11248).

Schittenhelm MM, Yee KW, Tyner JW, McGreevey L, Haley AD, Town A, Griffith DJ, Bainbridge T, Braziel RM, O'Farrell AM, Cherrington JM, Heinrich MC.

Leukemia. 2006 Nov;20(11):2008-14. Epub 2006 Sep 14.

PMID:
16990784
3.

Activating alleles of JAK3 in acute megakaryoblastic leukemia.

Walters DK, Mercher T, Gu TL, O'Hare T, Tyner JW, Loriaux M, Goss VL, Lee KA, Eide CA, Wong MJ, Stoffregen EP, McGreevey L, Nardone J, Moore SA, Crispino J, Boggon TJ, Heinrich MC, Deininger MW, Polakiewicz RD, Gilliland DG, Druker BJ.

Cancer Cell. 2006 Jul;10(1):65-75.

4.

Phosphoproteomic analysis of AML cell lines identifies leukemic oncogenes.

Walters DK, Goss VL, Stoffregen EP, Gu TL, Lee K, Nardone J, McGreevey L, Heinrich MC, Deininger MW, Polakiewicz R, Druker BJ.

Leuk Res. 2006 Sep;30(9):1097-104. Epub 2006 Feb 7.

PMID:
16464493
5.

PDGFRA mutations in gastrointestinal stromal tumors: frequency, spectrum and in vitro sensitivity to imatinib.

Corless CL, Schroeder A, Griffith D, Town A, McGreevey L, Harrell P, Shiraga S, Bainbridge T, Morich J, Heinrich MC.

J Clin Oncol. 2005 Aug 10;23(23):5357-64. Epub 2005 May 31. Review.

PMID:
15928335
6.

KIT gene deletions at the intron 10-exon 11 boundary in GI stromal tumors.

Corless CL, McGreevey L, Town A, Schroeder A, Bainbridge T, Harrell P, Fletcher JA, Heinrich MC.

J Mol Diagn. 2004 Nov;6(4):366-70.

7.

Synergistic effect of SU11248 with cytarabine or daunorubicin on FLT3 ITD-positive leukemic cells.

Yee KW, Schittenhelm M, O'Farrell AM, Town AR, McGreevey L, Bainbridge T, Cherrington JM, Heinrich MC.

Blood. 2004 Dec 15;104(13):4202-9. Epub 2004 Aug 10.

PMID:
15304385
8.

Effects of MLN518, a dual FLT3 and KIT inhibitor, on normal and malignant hematopoiesis.

Griswold IJ, Shen LJ, La Rosée P, Demehri S, Heinrich MC, Braziel RM, McGreevey L, Haley AD, Giese N, Druker BJ, Deininger MW.

Blood. 2004 Nov 1;104(9):2912-8. Epub 2004 Jul 8.

PMID:
15242881
9.

Detection of ABL kinase domain mutations with denaturing high-performance liquid chromatography.

Deininger MW, McGreevey L, Willis S, Bainbridge TM, Druker BJ, Heinrich MC.

Leukemia. 2004 Apr;18(4):864-71.

PMID:
14973502
10.

KIT mutations are common in testicular seminomas.

Kemmer K, Corless CL, Fletcher JA, McGreevey L, Haley A, Griffith D, Cummings OW, Wait C, Town A, Heinrich MC.

Am J Pathol. 2004 Jan;164(1):305-13.

11.

Kinase mutations and imatinib response in patients with metastatic gastrointestinal stromal tumor.

Heinrich MC, Corless CL, Demetri GD, Blanke CD, von Mehren M, Joensuu H, McGreevey LS, Chen CJ, Van den Abbeele AD, Druker BJ, Kiese B, Eisenberg B, Roberts PJ, Singer S, Fletcher CD, Silberman S, Dimitrijevic S, Fletcher JA.

J Clin Oncol. 2003 Dec 1;21(23):4342-9.

PMID:
14645423
12.

PDGFRA activating mutations in gastrointestinal stromal tumors.

Heinrich MC, Corless CL, Duensing A, McGreevey L, Chen CJ, Joseph N, Singer S, Griffith DJ, Haley A, Town A, Demetri GD, Fletcher CD, Fletcher JA.

Science. 2003 Jan 31;299(5607):708-10. Epub 2003 Jan 9.

13.

SU5416 and SU5614 inhibit kinase activity of wild-type and mutant FLT3 receptor tyrosine kinase.

Yee KW, O'Farrell AM, Smolich BD, Cherrington JM, McMahon G, Wait CL, McGreevey LS, Griffith DJ, Heinrich MC.

Blood. 2002 Oct 15;100(8):2941-9.

PMID:
12351406
14.

KIT mutations are common in incidental gastrointestinal stromal tumors one centimeter or less in size.

Corless CL, McGreevey L, Haley A, Town A, Heinrich MC.

Am J Pathol. 2002 May;160(5):1567-72.

15.

Fine-needle aspiration biopsy diagnosis of gastrointestinal stromal tumors using morphology, immunocytochemistry, and mutational analysis of c-kit.

Rader AE, Avery A, Wait CL, McGreevey LS, Faigel D, Heinrich MC.

Cancer. 2001 Aug 25;93(4):269-75.

PMID:
11507701

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