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Items: 45

1.

CtIP is required to initiate replication-dependent interstrand crosslink repair.

Duquette ML, Zhu Q, Taylor ER, Tsay AJ, Shi LZ, Berns MW, McGowan CH.

PLoS Genet. 2012;8(11):e1003050. doi: 10.1371/journal.pgen.1003050. Epub 2012 Nov 8.

2.

Cyclin-dependent kinase subunit (Cks) 1 or Cks2 overexpression overrides the DNA damage response barrier triggered by activated oncoproteins.

Liberal V, Martinsson-Ahlzén HS, Liberal J, Spruck CH, Widschwendter M, McGowan CH, Reed SI.

Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):2754-9. doi: 10.1073/pnas.1102434108. Epub 2011 Jun 22.

3.

Chk2 protects against radiation-induced genomic instability.

MacLaren A, Slavin D, McGowan CH.

Radiat Res. 2009 Oct;172(4):463-72. doi: 10.1667/RR1603.1.

PMID:
19772467
4.

Human SLX4 is a Holliday junction resolvase subunit that binds multiple DNA repair/recombination endonucleases.

Fekairi S, Scaglione S, Chahwan C, Taylor ER, Tissier A, Coulon S, Dong MQ, Ruse C, Yates JR 3rd, Russell P, Fuchs RP, McGowan CH, Gaillard PHL.

Cell. 2009 Jul 10;138(1):78-89. doi: 10.1016/j.cell.2009.06.029.

5.

Claspin and Chk1 regulate replication fork stability by different mechanisms.

Scorah J, McGowan CH.

Cell Cycle. 2009 Apr 1;8(7):1036-43. Epub 2009 Apr 2.

6.

MUS81 generates a subset of MLH1-MLH3-independent crossovers in mammalian meiosis.

Holloway JK, Booth J, Edelmann W, McGowan CH, Cohen PE.

PLoS Genet. 2008 Sep 12;4(9):e1000186. doi: 10.1371/journal.pgen.1000186.

7.

A conserved proliferating cell nuclear antigen-interacting protein sequence in Chk1 is required for checkpoint function.

Scorah J, Dong MQ, Yates JR 3rd, Scott M, Gillespie D, McGowan CH.

J Biol Chem. 2008 Jun 20;283(25):17250-9. doi: 10.1074/jbc.M800369200. Epub 2008 Apr 30.

8.

Cleavage mechanism of human Mus81-Eme1 acting on Holliday-junction structures.

Taylor ER, McGowan CH.

Proc Natl Acad Sci U S A. 2008 Mar 11;105(10):3757-62. doi: 10.1073/pnas.0710291105. Epub 2008 Feb 29.

9.

SUMO-targeted ubiquitin ligases in genome stability.

Prudden J, Pebernard S, Raffa G, Slavin DA, Perry JJ, Tainer JA, McGowan CH, Boddy MN.

EMBO J. 2007 Sep 19;26(18):4089-101. Epub 2007 Aug 30.

10.

A novel form of ataxia oculomotor apraxia characterized by oxidative stress and apoptosis resistance.

Gueven N, Becherel OJ, Howe O, Chen P, Haince JF, Ouellet ME, Poirier GG, Waterhouse N, Fusser M, Epe B, de Murcia JM, de Murcia G, McGowan CH, Parton R, Mothersill C, Grattan-Smith P, Lavin MF.

Cell Death Differ. 2007 Jun;14(6):1149-61. Epub 2007 Mar 9.

11.

Sws1 is a conserved regulator of homologous recombination in eukaryotic cells.

Martín V, Chahwan C, Gao H, Blais V, Wohlschlegel J, Yates JR 3rd, McGowan CH, Russell P.

EMBO J. 2006 Jun 7;25(11):2564-74. Epub 2006 May 18.

12.

Disruption of murine Mus81 increases genomic instability and DNA damage sensitivity but does not promote tumorigenesis.

Dendouga N, Gao H, Moechars D, Janicot M, Vialard J, McGowan CH.

Mol Cell Biol. 2005 Sep;25(17):7569-79.

13.

BLM helicase facilitates Mus81 endonuclease activity in human cells.

Zhang R, Sengupta S, Yang Q, Linke SP, Yanaihara N, Bradsher J, Blais V, McGowan CH, Harris CC.

Cancer Res. 2005 Apr 1;65(7):2526-31.

14.

The DNA damage response: sensing and signaling.

McGowan CH, Russell P.

Curr Opin Cell Biol. 2004 Dec;16(6):629-33. Review.

PMID:
15530773
15.

Running into problems: how cells cope with replicating damaged DNA.

McGowan CH.

Mutat Res. 2003 Nov 27;532(1-2):75-84. Review.

PMID:
14643430
16.
17.

RNA interference inhibition of Mus81 reduces mitotic recombination in human cells.

Blais V, Gao H, Elwell CA, Boddy MN, Gaillard PHL, Russell P, McGowan CH.

Mol Biol Cell. 2004 Feb;15(2):552-62. Epub 2003 Nov 14.

18.

Regulation of the eukaryotic cell cycle.

McGowan CH.

Prog Cell Cycle Res. 2003;5:1-4. Review.

PMID:
14593695
19.

Development and evaluation of a cabrito smoked sausage product.

Cosenza GH, Williams SK, Johnson DD, Sims C, McGowan CH.

Meat Sci. 2003 Jun;64(2):119-24.

PMID:
22062857
20.

Development and evaluation of a fermented cabrito snack stick product.

Cosenza GH, Williams SK, Johnson DD, Sims C, McGowan CH.

Meat Sci. 2003 May;64(1):51-7.

PMID:
22062662
21.

CHK2: a tumor suppressor or not?

McGowan CH.

Cell Cycle. 2002 Nov-Dec;1(6):401-3. Review. No abstract available.

PMID:
12548013
22.

Holliday junction resolution in human cells: two junction endonucleases with distinct substrate specificities.

Constantinou A, Chen XB, McGowan CH, West SC.

EMBO J. 2002 Oct 15;21(20):5577-85.

23.

Mammalian Polo-like kinase 3 (Plk3) is a multifunctional protein involved in stress response pathways.

Bahassi el M, Conn CW, Myer DL, Hennigan RF, McGowan CH, Sanchez Y, Stambrook PJ.

Oncogene. 2002 Sep 26;21(43):6633-40.

24.

Checking in on Cds1 (Chk2): A checkpoint kinase and tumor suppressor.

McGowan CH.

Bioessays. 2002 Jun;24(6):502-11. Review.

PMID:
12111733
25.

Human Mus81-associated endonuclease cleaves Holliday junctions in vitro.

Chen XB, Melchionna R, Denis CM, Gaillard PHL, Blasina A, Van de Weyer I, Boddy MN, Russell P, Vialard J, McGowan CH.

Mol Cell. 2001 Nov;8(5):1117-27.

26.

Serine-345 is required for Rad3-dependent phosphorylation and function of checkpoint kinase Chk1 in fission yeast.

Lopez-Girona A, Tanaka K, Chen XB, Baber BA, McGowan CH, Russell P.

Proc Natl Acad Sci U S A. 2001 Sep 25;98(20):11289-94. Epub 2001 Sep 11.

27.

Threonine-11, phosphorylated by Rad3 and atm in vitro, is required for activation of fission yeast checkpoint kinase Cds1.

Tanaka K, Boddy MN, Chen XB, McGowan CH, Russell P.

Mol Cell Biol. 2001 May;21(10):3398-404.

28.

Threonine 68 is required for radiation-induced phosphorylation and activation of Cds1.

Melchionna R, Chen XB, Blasina A, McGowan CH.

Nat Cell Biol. 2000 Oct;2(10):762-5.

PMID:
11025670
29.

Involvement of the MKK6-p38gamma cascade in gamma-radiation-induced cell cycle arrest.

Wang X, McGowan CH, Zhao M, He L, Downey JS, Fearns C, Wang Y, Huang S, Han J.

Mol Cell Biol. 2000 Jul;20(13):4543-52.

30.

Caffeine inhibits the checkpoint kinase ATM.

Blasina A, Price BD, Turenne GA, McGowan CH.

Curr Biol. 1999 Oct 7;9(19):1135-8.

31.

Cdc25 inhibited in vivo and in vitro by checkpoint kinases Cds1 and Chk1.

Furnari B, Blasina A, Boddy MN, McGowan CH, Russell P.

Mol Biol Cell. 1999 Apr;10(4):833-45.

32.

A human homologue of the checkpoint kinase Cds1 directly inhibits Cdc25 phosphatase.

Blasina A, de Weyer IV, Laus MC, Luyten WH, Parker AE, McGowan CH.

Curr Biol. 1999 Jan 14;9(1):1-10.

33.
34.

Cig2, a B-type cyclin, promotes the onset of S in Schizosaccharomyces pombe.

Mondesert O, McGowan CH, Russell P.

Mol Cell Biol. 1996 Apr;16(4):1527-33.

35.

Cell cycle regulation of human WEE1.

McGowan CH, Russell P.

EMBO J. 1995 May 15;14(10):2166-75.

36.

Effect of sex class on nutrient content of meat from young goat.

Johnson DD, Eastridge JS, Neubauer DR, McGowan CH.

J Anim Sci. 1995 Jan;73(1):296-301.

PMID:
7601747
37.

Protein phosphatase 2C, encoded by ptc1+, is important in the heat shock response of Schizosaccharomyces pombe.

Shiozaki K, Akhavan-Niaki H, McGowan CH, Russell P.

Mol Cell Biol. 1994 Jun;14(6):3742-51.

38.
39.

Evidence for the regulation of exocytic transport by protein phosphorylation.

Davidson HW, McGowan CH, Balch WE.

J Cell Biol. 1992 Mar;116(6):1343-55.

40.

Mammalian protein serine/threonine phosphatase 2C: cDNA cloning and comparative analysis of amino acid sequences.

Mann DJ, Campbell DG, McGowan CH, Cohen PT.

Biochim Biophys Acta. 1992 Feb 28;1130(1):100-4.

PMID:
1311954
41.

p80cdc25 mitotic inducer is the tyrosine phosphatase that activates p34cdc2 kinase in fission yeast.

Millar JB, McGowan CH, Lenaers G, Jones R, Russell P.

EMBO J. 1991 Dec;10(13):4301-9.

42.
43.

Protein phosphatase-2C from rabbit skeletal muscle and liver: an Mg2+-dependent enzyme.

McGowan CH, Cohen P.

Methods Enzymol. 1988;159:416-26. No abstract available.

PMID:
2842606
44.

Primary structure analysis proves that protein phosphatases 2C1 and 2C2 are isozymes.

McGowan CH, Campbell DG, Cohen P.

Biochim Biophys Acta. 1987 Sep 14;930(2):279-82.

PMID:
3040125
45.

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