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Chromatin interactions reveal novel gene targets for drug repositioning in rheumatic diseases.

Martin P, Ding J, Duffus K, Gaddi VP, McGovern A, Ray-Jones H, Yarwood A, Worthington J, Barton A, Orozco G.

Ann Rheum Dis. 2019 Aug;78(8):1127-1134. doi: 10.1136/annrheumdis-2018-214649. Epub 2019 May 15.


What to do with diabetes therapies when HbA1c lowering is inadequate: add, switch, or continue? A MASTERMIND study.

McGovern AP, Dennis JM, Shields BM, Hattersley AT, Pearson ER, Jones AG; MASTERMIND Consortium.

BMC Med. 2019 Apr 12;17(1):79. doi: 10.1186/s12916-019-1307-8.


Time trends in prescribing of type 2 diabetes drugs, glycaemic response and risk factors: A retrospective analysis of primary care data, 2010-2017.

Dennis JM, Henley WE, McGovern AP, Farmer AJ, Sattar N, Holman RR, Pearson ER, Hattersley AT, Shields BM, Jones AG; MASTERMIND consortium.

Diabetes Obes Metab. 2019 Jul;21(7):1576-1584. doi: 10.1111/dom.13687. Epub 2019 Apr 4.


The impact of therapy on the risk of asthma in type 2 diabetes.

Rayner LH, Mcgovern A, Sherlock J, Gatenby P, Correa A, Creagh-Brown B, deLusignan S.

Clin Respir J. 2019 May;13(5):299-305. doi: 10.1111/crj.13011. Epub 2019 Apr 2.


Translational review: Neuroimmune mechanisms in cough and emerging therapeutic targets.

McGovern AE, Short KR, Kywe Moe AA, Mazzone SB.

J Allergy Clin Immunol. 2018 Nov;142(5):1392-1402. doi: 10.1016/j.jaci.2018.09.004. Review.


Cholinergic basal forebrain neurons regulate fear extinction consolidation through p75 neurotrophin receptor signaling.

Boskovic Z, Milne MR, Qian L, Clifton HD, McGovern AE, Turnbull MT, Mazzone SB, Coulson EJ.

Transl Psychiatry. 2018 Sep 21;8(1):199. doi: 10.1038/s41398-018-0248-x.


Incidence and prevalence of cardiovascular disease in English primary care: a cross-sectional and follow-up study of the Royal College of General Practitioners (RCGP) Research and Surveillance Centre (RSC).

Hinton W, McGovern A, Coyle R, Han TS, Sharma P, Correa A, Ferreira F, de Lusignan S.

BMJ Open. 2018 Aug 20;8(8):e020282. doi: 10.1136/bmjopen-2017-020282.


Reflex regulation of breathing by the paratrigeminal nucleus via multiple bulbar circuits.

Driessen AK, Farrell MJ, Dutschmann M, Stanic D, McGovern AE, Mazzone SB.

Brain Struct Funct. 2018 Dec;223(9):4005-4022. doi: 10.1007/s00429-018-1732-z. Epub 2018 Aug 16.


Type 2 Diabetes and Asthma: Systematic Review of the Bidirectional Relationship.

Rayner L, McGovern A, Creagh-Brown B, Woodmansey C, de Lusignan S.

Curr Diabetes Rev. 2019;15(2):118-126. doi: 10.2174/1573399814666180711114859.


Type 2 diabetes: A protective factor for COPD?

Rayner LH, McGovern AP, Sherlock J, Gatenby P, Correa A, Creagh-Brown B, de Lusignan S.

Prim Care Diabetes. 2018 Oct;12(5):438-444. doi: 10.1016/j.pcd.2018.05.002. Epub 2018 May 26.


Glycemic control is an important modifiable risk factor for uveitis in patients with diabetes: A retrospective cohort study establishing clinical risk and ophthalmic disease burden.

Ansari AS, de Lusignan S, Hinton W, Munro N, Taylor S, McGovern A.

J Diabetes Complications. 2018 Jun;32(6):602-608. doi: 10.1016/j.jdiacomp.2018.03.008. Epub 2018 Mar 23.


Hippocampal modulation of cardiorespiratory function.

Ajayi IE, McGovern AE, Driessen AK, Kerr NF, Mills PC, Mazzone SB.

Respir Physiol Neurobiol. 2018 Jun;252-253:18-27. doi: 10.1016/j.resp.2018.03.004. Epub 2018 Mar 14.


Evaluation of the Cepheid® Xpert®C. difficile binary toxin (BT) diagnostic assay.

McGovern AM, Androga GO, Moono P, Collins DA, Foster NF, Chang BJ, Riley TV.

Anaerobe. 2018 Jun;51:12-16. doi: 10.1016/j.anaerobe.2018.03.004. Epub 2018 Mar 11.


Ischaemic stroke, haemorrhage, and mortality in older patients with chronic kidney disease newly started on anticoagulation for atrial fibrillation: a population based study from UK primary care.

Kumar S, de Lusignan S, McGovern A, Correa A, Hriskova M, Gatenby P, Jones S, Goldsmith D, Camm AJ.

BMJ. 2018 Feb 14;360:k342. doi: 10.1136/bmj.k342.


A Class Comparison of Medication Persistence in People with Type 2 Diabetes: A Retrospective Observational Study.

McGovern A, Hinton W, Calderara S, Munro N, Whyte M, de Lusignan S.

Diabetes Ther. 2018 Feb;9(1):229-242. doi: 10.1007/s13300-017-0361-5. Epub 2018 Jan 4.


A neuroanatomical framework for the central modulation of respiratory sensory processing and cough by the periaqueductal grey.

McGovern AE, Ajayi IE, Farrell MJ, Mazzone SB.

J Thorac Dis. 2017 Oct;9(10):4098-4107. doi: 10.21037/jtd.2017.08.119. Review.


Comparison of medication adherence and persistence in type 2 diabetes: A systematic review and meta-analysis.

McGovern A, Tippu Z, Hinton W, Munro N, Whyte M, de Lusignan S.

Diabetes Obes Metab. 2018 Apr;20(4):1040-1043. doi: 10.1111/dom.13160. Epub 2017 Dec 12.


U-shaped relationship between serum phosphate and cardiovascular risk: A retrospective cohort study.

Hayward N, McGovern A, de Lusignan S, Cole N, Hinton W, Jones S.

PLoS One. 2017 Nov 8;12(11):e0184774. doi: 10.1371/journal.pone.0184774. eCollection 2017.


Prevalence of binary toxin positive Clostridium difficile in diarrhoeal humans in the absence of epidemic ribotype 027.

McGovern AM, Androga GO, Knight DR, Watson MW, Elliott B, Foster NF, Chang BJ, Riley TV.

PLoS One. 2017 Nov 8;12(11):e0187658. doi: 10.1371/journal.pone.0187658. eCollection 2017.


Incidence, Demographics, and Clinical Characteristics of Diabetes of the Exocrine Pancreas (Type 3c): A Retrospective Cohort Study.

Woodmansey C, McGovern AP, McCullough KA, Whyte MB, Munro NM, Correa AC, Gatenby PAC, Jones SA, de Lusignan S.

Diabetes Care. 2017 Nov;40(11):1486-1493. doi: 10.2337/dc17-0542. Epub 2017 Aug 31.


Advances in Psychotherapy for Depressed Older Adults.

Raue PJ, McGovern AR, Kiosses DN, Sirey JA.

Curr Psychiatry Rep. 2017 Sep;19(9):57. doi: 10.1007/s11920-017-0812-8. Review.


The association between diabetes, level of glycaemic control and eye infection: Cohort database study.

Ansari AS, de Lusignan S, Hinton W, Munro N, McGovern A.

Prim Care Diabetes. 2017 Oct;11(5):421-429. doi: 10.1016/j.pcd.2017.05.009. Epub 2017 Jun 23.


Rewriting Electron-Transfer Kinetics at Pyrolytic Carbon Electrodes Decorated with Nanometric Ruthenium Oxide.

Parker JF, Kamm GE, McGovern AD, DeSario PA, Rolison DR, Lytle JC, Long JW.

Langmuir. 2017 Sep 19;33(37):9416-9425. doi: 10.1021/acs.langmuir.7b01107. Epub 2017 Jun 15.


Translating Cough Mechanisms Into Better Cough Suppressants.

Keller JA, McGovern AE, Mazzone SB.

Chest. 2017 Oct;152(4):833-841. doi: 10.1016/j.chest.2017.05.016. Epub 2017 May 25. Review.


Measuring Quality of Healthcare Outcomes in Type 2 Diabetes from Routine Data: a Seven-nation Survey Conducted by the IMIA Primary Health Care Working Group.

Hinton W, Liyanage H, McGovern A, Liaw ST, Kuziemsky C, Munro N, de Lusignan S.

Yearb Med Inform. 2017 Aug;26(1):201-208. doi: 10.15265/IY-2017-005. Epub 2017 Sep 11.


Ethnicity Recording in Primary Care Computerised Medical Record Systems: An Ontological Approach.

Tippu Z, Correa A, Liyanage H, Burleigh D, McGovern A, Van Vlymen J, Jones S, De Lusignan S.

J Innov Health Inform. 2017 Mar 14;23(4):920. doi: 10.14236/jhi.v23i4.920.


Sodium-Glucose Co-transporter 2 (SGLT2) Inhibitor: Comparing Trial Data and Real-World Use.

McGovern A, Feher M, Munro N, de Lusignan S.

Diabetes Ther. 2017 Apr;8(2):365-376. doi: 10.1007/s13300-017-0254-7. Epub 2017 Mar 21.


Sodium-Glucose Co-Transporter-2 (SGLT2) Inhibitors: Comparing Trial and Real World Use (Study Protocol).

McGovern A, Feher M, Munro N, de Lusignan S.

Diabetes Ther. 2017 Apr;8(2):355-363. doi: 10.1007/s13300-017-0229-8. Epub 2017 Jan 30.


Central mechanisms of airway sensation and cough hypersensitivity.

Driessen AK, McGovern AE, Narula M, Yang SK, Keller JA, Farrell MJ, Mazzone SB.

Pulm Pharmacol Ther. 2017 Dec;47:9-15. doi: 10.1016/j.pupt.2017.01.010. Epub 2017 Jan 27. Review.


Association Between Diabetes, Level of Glycemic Control, and Eye Infection: A Cohort Study.

Ansari AS, de Lusignan S, Arrowsmith B, Hinton W, Munro N, McGovern A.

Diabetes Care. 2017 Mar;40(3):e30-e31. doi: 10.2337/dc16-2320. Epub 2016 Dec 29. No abstract available.


Real-world evidence studies into treatment adherence, thresholds for intervention and disparities in treatment in people with type 2 diabetes in the UK.

McGovern A, Hinton W, Correa A, Munro N, Whyte M, de Lusignan S.

BMJ Open. 2016 Nov 24;6(11):e012801. doi: 10.1136/bmjopen-2016-012801.


Identifying Causal Genes at the Multiple Sclerosis Associated Region 6q23 Using Capture Hi-C.

Martin P, McGovern A, Massey J, Schoenfelder S, Duffus K, Yarwood A, Barton A, Worthington J, Fraser P, Eyre S, Orozco G.

PLoS One. 2016 Nov 18;11(11):e0166923. doi: 10.1371/journal.pone.0166923. eCollection 2016.


Capture Hi-C identifies a novel causal gene, IL20RA, in the pan-autoimmune genetic susceptibility region 6q23.

McGovern A, Schoenfelder S, Martin P, Massey J, Duffus K, Plant D, Yarwood A, Pratt AG, Anderson AE, Isaacs JD, Diboll J, Thalayasingam N, Ospelt C, Barton A, Worthington J, Fraser P, Eyre S, Orozco G.

Genome Biol. 2016 Nov 1;17(1):212.


Physician Associate and General Practitioner Consultations: A Comparative Observational Video Study.

de Lusignan S, McGovern AP, Tahir MA, Hassan S, Jones S, Halter M, Joly L, Drennan VM.

PLoS One. 2016 Aug 25;11(8):e0160902. doi: 10.1371/journal.pone.0160902. eCollection 2016.


Association between glycaemic control and common infections in people with Type 2 diabetes: a cohort study.

Hine JL, de Lusignan S, Burleigh D, Pathirannehelage S, McGovern A, Gatenby P, Jones S, Jiang D, Williams J, Elliot AJ, Smith GE, Brownrigg J, Hinchliffe R, Munro N.

Diabet Med. 2017 Apr;34(4):551-557. doi: 10.1111/dme.13205. Epub 2016 Sep 22.


Royal College of General Practitioners Research and Surveillance Centre (RCGP RSC) sentinel network: a cohort profile.

Correa A, Hinton W, McGovern A, van Vlymen J, Yonova I, Jones S, de Lusignan S.

BMJ Open. 2016 Apr 20;6(4):e011092. doi: 10.1136/bmjopen-2016-011092.


Use of FACE-Q to Measure Quality of Life Following Aesthetic Facial Treatments-Reply.

Jacono AA, Chastant RP, McGovern AR.

JAMA Facial Plast Surg. 2016 Mar-Apr;18(2):149. doi: 10.1001/jamafacial.2016.0004. No abstract available.


Systematic review of adherence rates by medication class in type 2 diabetes: a study protocol.

McGovern A, Tippu Z, Hinton W, Munro N, Whyte M, de Lusignan S.

BMJ Open. 2016 Feb 29;6(2):e010469. doi: 10.1136/bmjopen-2015-010469.


Infection risk in elderly people with reduced glycaemic control.

McGovern AP, Hine J, de Lusignan S.

Lancet Diabetes Endocrinol. 2016 Apr;4(4):303-4. doi: 10.1016/S2213-8587(16)00043-7. Epub 2016 Feb 16. No abstract available.


Glucose test provenance recording in UK primary care: was that fasted or random?

McGovern AP, Fieldhouse H, Tippu Z, Jones S, Munro N, de Lusignan S.

Diabet Med. 2017 Jan;34(1):93-98. doi: 10.1111/dme.13067. Epub 2016 Feb 11.


Changes in Depression and Stress after Release from a Tobacco-Free Prison in the United States.

van den Berg JJ, Roberts MB, Bock BC, Martin RA, Stein LA, Parker DR, McGovern AR, Shuford SH, Clarke JG.

Int J Environ Res Public Health. 2016 Jan 12;13(1). pii: E114. doi: 10.3390/ijerph13010114.


The Role of the Paratrigeminal Nucleus in Vagal Afferent Evoked Respiratory Reflexes: A Neuroanatomical and Functional Study in Guinea Pigs.

Driessen AK, Farrell MJ, Mazzone SB, McGovern AE.

Front Physiol. 2015 Dec 21;6:378. doi: 10.3389/fphys.2015.00378. eCollection 2015.


Test Accuracy of Informant-Based Cognitive Screening Tests for Diagnosis of Dementia and Multidomain Cognitive Impairment in Stroke.

McGovern A, Pendlebury ST, Mishra NK, Fan Y, Quinn TJ.

Stroke. 2016 Feb;47(2):329-35. doi: 10.1161/STROKEAHA.115.011218. Epub 2015 Dec 17. Review.


Capture Hi-C reveals novel candidate genes and complex long-range interactions with related autoimmune risk loci.

Martin P, McGovern A, Orozco G, Duffus K, Yarwood A, Schoenfelder S, Cooper NJ, Barton A, Wallace C, Fraser P, Worthington J, Eyre S.

Nat Commun. 2015 Nov 30;6:10069. doi: 10.1038/ncomms10069.


Basing approval of drugs for type 2 diabetes on real world outcomes.

McGovern A, Hinchliffe R, Munro N, de Lusignan S.

BMJ. 2015 Nov 3;351:h5829. doi: 10.1136/bmj.h5829. No abstract available.


A systematic study comparing aspirate versus trephine for quantifying plasma cell infiltration in newly-diagnosed myeloma.

Gabriel J, McGovern A, Robinson S, Wright D, Chevassut T.

Br J Haematol. 2016 Sep;174(5):818-20. doi: 10.1111/bjh.13807. Epub 2015 Oct 22. No abstract available.


Multiple neural circuits mediating airway sensations: Recent advances in the neurobiology of the urge-to-cough.

Driessen AK, Farrell MJ, Mazzone SB, McGovern AE.

Respir Physiol Neurobiol. 2016 Jun;226:115-20. doi: 10.1016/j.resp.2015.09.017. Epub 2015 Oct 9. Review.


Depression and Suicidal Ideation During Two Psychosocial Treatments in Older Adults with Major Depression and Dementia.

Kiosses DN, Rosenberg PB, McGovern A, Fonzetti P, Zaydens H, Alexopoulos GS.

J Alzheimers Dis. 2015;48(2):453-62. doi: 10.3233/JAD-150200.


Improving the measurement of longitudinal change in renal function: automated detection of changes in laboratory creatinine assay.

Poh N, McGovern AP, de Lusignan S.

J Innov Health Inform. 2015 Apr 14;22(2):293-301. doi: 10.14236/jhi.v22i2.81.


Cognitive control, reward-related decision making and outcomes of late-life depression treated with an antidepressant.

Alexopoulos GS, Manning K, Kanellopoulos D, McGovern A, Seirup JK, Banerjee S, Gunning F.

Psychol Med. 2015 Oct;45(14):3111-20. doi: 10.1017/S0033291715001075. Epub 2015 Jul 14.

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