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The relationship between physical examination and ultrasonography for large entheses is best for the Achilles tendon and patellar tendon origin.

Aydin SZ, Bakirci S, Kasapoglu E, Castillo-Gallego C, Alhussain FA, Ash ZR, Kurum E, McGonagle D, Marzo-Ortega H, Gladman D, Eder L.

J Rheumatol. 2019 Sep 1. pii: jrheum.190169. doi: 10.3899/jrheum.190169. [Epub ahead of print]


The novel cytokine Metrnl/IL-41 is elevated in Psoriatic Arthritis synovium and inducible from both entheseal and synovial fibroblasts.

Bridgewood C, Russell T, Weedon H, Baboolal T, Watad A, Sharif K, Cuthbert R, Wittmann M, Wechalekar M, McGonagle D.

Clin Immunol. 2019 Aug 27;208:108253. doi: 10.1016/j.clim.2019.108253. [Epub ahead of print]


Predominant ultrasonographic extracapsular changes in symptomatic psoriatic dactylitis: results from a multicenter cross-sectional study comparing symptomatic and asymptomatic hand dactylitis.

Girolimetto N, Macchioni P, Tinazzi I, Costa L, Peluso R, Tasso M, Bascherini V, Addimanda O, Marchetta A, Possemato N, Salvarani C, McGonagle D, Scarpa R, Caso F.

Clin Rheumatol. 2019 Jul 13. doi: 10.1007/s10067-019-04683-2. [Epub ahead of print]


Response to: 'Synovial cellular and molecular signatures stratify clinical response to csDMARD therapy and predict radiographic progression in early rheumatoid arthritis patients' by Humby et al.

Buch MH, Melville A, McGonagle DG.

Ann Rheum Dis. 2019 Jul 13. pii: annrheumdis-2019-215881. doi: 10.1136/annrheumdis-2019-215881. [Epub ahead of print] No abstract available.


Evidence that systemic therapies for psoriasis may reduce psoriatic arthritis occurrence.

Solmaz D, Ehlebracht A, Karsh J, Bakirci S, McGonagle D, Aydin SZ.

Clin Exp Rheumatol. 2019 Jun 28. [Epub ahead of print]


The role of IL-17A in axial spondyloarthritis and psoriatic arthritis: recent advances and controversies.

McGonagle DG, McInnes IB, Kirkham BW, Sherlock J, Moots R.

Ann Rheum Dis. 2019 Sep;78(9):1167-1178. doi: 10.1136/annrheumdis-2019-215356. Epub 2019 Jul 5. Review.


Gene expression and functional comparison between multipotential stromal cells from lateral and medial condyles of knee osteoarthritis patients.

Sanjurjo-Rodriguez C, Baboolal TG, Burska AN, Ponchel F, El-Jawhari JJ, Pandit H, McGonagle D, Jones E.

Sci Rep. 2019 Jun 27;9(1):9321. doi: 10.1038/s41598-019-45820-w.


The simultaneous analysis of mesenchymal stem cells and early osteocytes accumulation in osteoarthritic femoral head sclerotic bone.

Ilas DC, Churchman SM, Baboolal T, Giannoudis PV, Aderinto J, McGonagle D, Jones E.

Rheumatology (Oxford). 2019 Apr 16. pii: kez130. doi: 10.1093/rheumatology/kez130. [Epub ahead of print]


Identification of senescent cells in multipotent mesenchymal stromal cell cultures: Current methods and future directions.

Zhai W, Yong D, El-Jawhari JJ, Cuthbert R, McGonagle D, Win Naing M, Jones E.

Cytotherapy. 2019 Aug;21(8):803-819. doi: 10.1016/j.jcyt.2019.05.001. Epub 2019 May 25. Review.


Initial assessment of the early arthritis for psoriatic patients diagnostic questionnaire in dermatology clinics in Australia, Korea and China.

Jo SJ, Foley P, Oakley SP, Zhang J, Zheng M, Shin K, McGonagle D, Gisondi P, Tinazzi I, Butcher BE, Handel M.

Int J Rheum Dis. 2019 Aug;22(8):1512-1520. doi: 10.1111/1756-185X.13604. Epub 2019 May 22.


Ultrasonographic evidence of predominance of acute extracapsular and chronic intrasynovial patterns in 100 psoriatic hand dactylitis.

Girolimetto N, Macchioni P, Tinazzi I, Costa L, McGonagle D, Peluso R, Del Puente A, Addimanda O, Marchetta A, Possemato N, Tasso M, Salvarani C, Scarpa R, Caso F.

J Rheumatol. 2019 May 15. pii: jrheum.190046. doi: 10.3899/jrheum.190046. [Epub ahead of print]


The role of obesity on inflammation and damage in spondyloarthritis: a systematic literature review on body mass index and imaging.

Bakirci S, Dabague J, Eder L, McGonagle D, Aydin SZ.

Clin Exp Rheumatol. 2019 Apr 29. [Epub ahead of print] Review.


Autoantibody status in systemic sclerosis patients defines both cancer risk and survival with ANA negativity in cases with concomitant cancer having a worse survival.

Watad A, McGonagle D, Bragazzi NL, Tiosano S, Comaneshter D, Shoenfeld Y, Cohen AD, Amital H.

Oncoimmunology. 2019 Mar 24;8(6):e1588084. doi: 10.1080/2162402X.2019.1588084. eCollection 2019.


Correction to: The IL-23p19/EBI3 heterodimeric cytokine termed IL-39 remains a theoretical cytokine in man.

Bridgewood C, Alase A, Watad A, Wittmann M, Cuthbert R, McGonagle D.

Inflamm Res. 2019 Jun;68(6):427. doi: 10.1007/s00011-019-01242-y.


Recommendations for acquisition and interpretation of MRI of the spine and sacroiliac joints in the diagnosis of axial spondyloarthritis in the UK.

Bray TJP, Jones A, Bennett AN, Conaghan PG, Grainger A, Hodgson R, Hutchinson C, Leandro M, Mandl P, McGonagle D, O'Connor P, Sengupta R, Thomas M, Toms A, Winn N, Hall-Craggs MA, Marzo-Ortega H, Machado PM; British Society of Spondyloarthritis (BRITSpA).

Rheumatology (Oxford). 2019 May 2. pii: kez173. doi: 10.1093/rheumatology/kez173. [Epub ahead of print]


Identification of myeloid cells in the human enthesis as the main source of local IL-23 production.

Bridgewood C, Watad A, Russell T, Palmer TM, Marzo-Ortega H, Khan A, Millner PA, Dunsmuir R, Rao A, Loughenbury P, Wittmann M, Cuthbert RJ, McGonagle DG.

Ann Rheum Dis. 2019 Jul;78(7):929-933. doi: 10.1136/annrheumdis-2018-214944. Epub 2019 Apr 24.


Systemic Sclerosis is Linked to Psoriasis and May Impact on Patients' Survival: A Large Cohort Study.

Watad A, Bragazzi NL, McGonagle D, Damiani G, Comaneshter D, Cohen A, Amital H.

J Clin Med. 2019 Apr 16;8(4). pii: E521. doi: 10.3390/jcm8040521.


The IL-23p19/EBI3 heterodimeric cytokine termed IL-39 remains a theoretical cytokine in man.

Bridgewood C, Alase A, Watad A, Wittmann M, Cuthbert R, McGonagle D.

Inflamm Res. 2019 Jun;68(6):423-426. doi: 10.1007/s00011-019-01235-x. Epub 2019 Apr 13. Erratum in: Inflamm Res. 2019 May 7;:.


Autoimmune/inflammatory syndrome induced by adjuvants (ASIA) demonstrates distinct autoimmune and autoinflammatory disease associations according to the adjuvant subtype: Insights from an analysis of 500 cases.

Watad A, Bragazzi NL, McGonagle D, Adawi M, Bridgewood C, Damiani G, Alijotas-Reig J, Esteve-Valverde E, Quaresma M, Amital H, Shoenfeld Y.

Clin Immunol. 2019 Jun;203:1-8. doi: 10.1016/j.clim.2019.03.007. Epub 2019 Mar 25.


The Impact of Intermittent Fasting (Ramadan Fasting) on Psoriatic Arthritis Disease Activity, Enthesitis, and Dactylitis: A Multicentre Study.

Adawi M, Damiani G, Bragazzi NL, Bridgewood C, Pacifico A, Conic RRZ, Morrone A, Malagoli P, Pigatto PDM, Amital H, McGonagle D, Watad A.

Nutrients. 2019 Mar 12;11(3). pii: E601. doi: 10.3390/nu11030601.


Comment on: Emergence of severe spondyloarthropathy-related entheseal pathology following successful vedolizumab therapy for inflammatory bowel disease: reply.

Dubash S, Marzo-Ortega H, McGonagle D.

Rheumatology (Oxford). 2019 Jun 1;58(6):1115-1117. doi: 10.1093/rheumatology/kez053. No abstract available.


A comparison of apremilast monotherapy and combination therapy for psoriatic arthritis in a real-life setting: Data from the Leeds Combined Psoriatic Service.

Abignano G, Fadl N, Merashli M, Vandevelde C, Freeston J, McGonagle D, Marzo-Ortega H.

J Am Acad Dermatol. 2019 Jun;80(6):1796-1798. doi: 10.1016/j.jaad.2019.02.014. Epub 2019 Feb 13. No abstract available.


Pathophysiology, assessment and treatment of psoriatic dactylitis.

McGonagle D, Tan AL, Watad A, Helliwell P.

Nat Rev Rheumatol. 2019 Feb;15(2):113-122. doi: 10.1038/s41584-018-0147-9. Review.


The advent of IL-17A blockade in ankylosing spondylitis: secukinumab, ixekizumab and beyond.

Dubash S, Bridgewood C, McGonagle D, Marzo-Ortega H.

Expert Rev Clin Immunol. 2019 Feb;15(2):123-134. doi: 10.1080/1744666X.2019.1561281. Epub 2019 Jan 8. Review.


Symptomatic psoriatic dactylitis is associated with ultrasound determined extra-synovial inflammatory features and shorter disease duration.

Girolimetto N, Costa L, Mancarella L, Addimanda O, Bottiglieri P, Santelli F, Meliconi R, Peluso R, Del Puente A, Macchioni P, Salvarani C, McGonagle D, Scarpa R, Caso F.

Clin Rheumatol. 2019 Mar;38(3):903-911. doi: 10.1007/s10067-018-4400-z. Epub 2018 Dec 19.


The Early Phases of Ankylosing Spondylitis: Emerging Insights From Clinical and Basic Science.

Watad A, Bridgewood C, Russell T, Marzo-Ortega H, Cuthbert R, McGonagle D.

Front Immunol. 2018 Nov 16;9:2668. doi: 10.3389/fimmu.2018.02668. eCollection 2018. Review.


Regression of Peripheral Subclinical Enthesopathy in Therapy-Naive Patients Treated With Ustekinumab for Moderate-to-Severe Chronic Plaque Psoriasis: A Fifty-Two-Week, Prospective, Open-Label Feasibility Study.

Savage L, Goodfield M, Horton L, Watad A, Hensor E, Emery P, Wakefield R, Wittmann M, McGonagle D.

Arthritis Rheumatol. 2019 Apr;71(4):626-631. doi: 10.1002/art.40778. Epub 2019 Mar 4.


A Novel Arthroscopic Technique for Intraoperative Mobilization of Synovial Mesenchymal Stem Cells.

Baboolal TG, Khalil-Khan A, Theodorides AA, Wall O, Jones E, McGonagle D.

Am J Sports Med. 2018 Dec;46(14):3532-3540. doi: 10.1177/0363546518803757. Epub 2018 Nov 12.


Advancing research paradigms and pathophysiological pathways in psoriatic arthritis and ankylosing spondylitis: Proceedings of the 2017 Platform for the Exchange of Expertise and Research (PEER) meeting.

Abraham S, Barton A, Eder L, Lim A, McGonagle D, McHugh N, Pennington S, Sengupta R, Siebert S, Bowness P, Schafer PH, Cullen E, FitzGerald O.

Semin Arthritis Rheum. 2019 Jun;48(6):1005-1013. doi: 10.1016/j.semarthrit.2018.10.008. Epub 2018 Oct 15. No abstract available.


Immunogenicity, safety and tolerability of anti-pneumococcal vaccination in systemic lupus erythematosus patients: An evidence-informed and PRISMA compliant systematic review and meta-analysis.

Adawi M, Bragazzi NL, McGonagle D, Watad S, Mahroum N, Damiani G, Conic R, Bridgewood C, Mahagna H, Giacomelli L, Eggenhöffner R, Mahamid M, Pigatto PDM, Amital H, Watad A.

Autoimmun Rev. 2019 Jan;18(1):73-92. doi: 10.1016/j.autrev.2018.08.002. Epub 2018 Nov 5.


Publisher Correction: A novel two-score system for interferon status segregates autoimmune diseases and correlates with clinical features.

El-Sherbiny YM, Psarras A, Md Yusof MY, Hensor EMA, Tooze R, Doody G, Mohamed AAA, McGonagle D, Wittmann M, Emery P, Vital EM.

Sci Rep. 2018 Oct 1;8(1):14846. doi: 10.1038/s41598-018-33062-1.


The burden of depression in systemic sclerosis patients: a nationwide population-based study.

Bragazzi NL, Watad A, Gizunterman A, McGonagle D, Mahagna H, Comaneshter D, Amital H, Cohen AD, Amital D.

J Affect Disord. 2019 Jan 15;243:427-431. doi: 10.1016/j.jad.2018.09.075. Epub 2018 Sep 21.


Greater magnitude of entheseal microdamage and repair in psoriatic arthritis compared with ankylosing spondylitis on ultrasound.

Arslan Alhussain F, Kasapoglu Gunal E, Kurum E, Bakirci S, Ozturk AB, McGonagle D, Aydin SZ.

Rheumatology (Oxford). 2019 Feb 1;58(2):299-303. doi: 10.1093/rheumatology/key238.


Three-dimensional nail imaging by optical coherence tomography: a novel biomarker of response to therapy for nail disease in psoriasis and psoriatic arthritis.

Abignano G, Laws P, Del Galdo F, Marzo-Ortega H, McGonagle D.

Clin Exp Dermatol. 2019 Jun;44(4):462-465. doi: 10.1111/ced.13786. Epub 2018 Sep 23. No abstract available.


Arthritis Mutilans in Systemic Sclerosis.

Abignano G, Mennillo GA, Lettieri G, Padula A, McGonagle D, D'Angelo S.

Arthritis Rheumatol. 2019 Jan;71(1):120. doi: 10.1002/art.40723. Epub 2018 Nov 24. No abstract available.


Mechanistic immunological based classification of rheumatoid arthritis.

McGonagle D, Watad A, Savic S.

Autoimmun Rev. 2018 Nov;17(11):1115-1123. doi: 10.1016/j.autrev.2018.06.001. Epub 2018 Sep 11. Review.


Emergence of severe spondyloarthropathy-related entheseal pathology following successful vedolizumab therapy for inflammatory bowel disease.

Dubash S, Marianayagam T, Tinazzi I, Al-Araimi T, Pagnoux C, Weizman AV, Richette P, Tran Minh ML, Allez M, Singh A, Ciccia F, Hamlin J, Tan AL, Marzo-Ortega H, McGonagle D.

Rheumatology (Oxford). 2019 Jun 1;58(6):963-968. doi: 10.1093/rheumatology/key267.


T cell immunomodulation by clinically used allogeneic human cancellous bone fragments: a potential novel immunotherapy tool.

El-Sherbiny YM, El-Jawhari JJ, Moseley TA, McGonagle D, Jones E.

Sci Rep. 2018 Sep 10;8(1):13535. doi: 10.1038/s41598-018-31979-1.


Acute Unilateral Sacroiliitis Mimicking Infection on Magnetic Resonance Imaging with Response to Nonsteroidal Antiinflammatory Drugs: A Distinct Presentation of Spondyloarthritis?

Dubash S, Pease C, Aslam A, Coady D, McGONAGLE D, Marzo-Ortega H.

J Rheumatol. 2018 Dec;45(12):1708-1710. doi: 10.3899/jrheum.171456. Epub 2018 Aug 15. No abstract available.


Imaging of nuclear magnetic resonance spin-lattice relaxation activation energy in cartilage.

Foster RJ, Damion RA, Ries ME, Smye SW, McGonagle DG, Binks DA, Radjenovic A.

R Soc Open Sci. 2018 Jul 11;5(7):180221. doi: 10.1098/rsos.180221. eCollection 2018 Jul.


Combined inhibition of tumour necrosis factor-alpha and interleukin-12/23 for long-standing, refractory psoriatic disease: a differential role for cytokine pathways?

De Marco G, McGonagle D, Mathieson HR, Merashli M, Magee C, FitzGerald O, Goodfield M, Marzo-Ortega H.

Rheumatology (Oxford). 2018 Nov 1;57(11):2053-2055. doi: 10.1093/rheumatology/key199. No abstract available.


Spondyloarthritis: new insights into clinical aspects, translational immunology and therapeutics.

Bridgewood C, Watad A, Cuthbert RJ, McGonagle D.

Curr Opin Rheumatol. 2018 Sep;30(5):526-532. doi: 10.1097/BOR.0000000000000529. Review.


Enthesitis: Much More Than Focal Insertion Point Inflammation.

Watad A, Cuthbert RJ, Amital H, McGonagle D.

Curr Rheumatol Rep. 2018 May 30;20(7):41. doi: 10.1007/s11926-018-0751-3. Review.


Similar subclinical enthesitis in celiac and inflammatory bowel diseases by ultrasound suggests a gut enthesis axis independent of spondyloarthropathy spectrum.

Bakirci Ureyen S, Karacaer C, Toka B, Erturk Z, Eminler AT, Kaya M, Tascilar K, Tamer A, Uslan I, Kurum E, McGonagle D, Aydin SZ.

Rheumatology (Oxford). 2018 Aug 1;57(8):1417-1422. doi: 10.1093/rheumatology/key102.


A novel two-score system for interferon status segregates autoimmune diseases and correlates with clinical features.

El-Sherbiny YM, Psarras A, Md Yusof MY, Hensor EMA, Tooze R, Doody G, Mohamed AAA, McGonagle D, Wittmann M, Emery P, Vital EM.

Sci Rep. 2018 Apr 11;8(1):5793. doi: 10.1038/s41598-018-24198-1. Erratum in: Sci Rep. 2018 Oct 1;8(1):14846.


The rationale for Janus kinase inhibitors for the treatment of spondyloarthritis.

Veale DJ, McGonagle D, McInnes IB, Krueger JG, Ritchlin CT, Elewaut D, Kanik KS, Hendrikx T, Berstein G, Hodge J, Telliez JB.

Rheumatology (Oxford). 2019 Feb 1;58(2):197-205. doi: 10.1093/rheumatology/key070.


Assessment of two screening tools to identify psoriatic arthritis in patients with psoriasis.

Coates LC, Savage LJ, Chinoy H, Laws PM, Lovell CR, Korendowych E, Mahmood F, Mathieson HR, McGonagle D, Warren RB, Waxman R, Helliwell PS.

J Eur Acad Dermatol Venereol. 2018 Sep;32(9):1530-1534. doi: 10.1111/jdv.14971. Epub 2018 May 9.


Comprehensive evaluation of finger flexor tendon entheseal soft tissue and bone changes by ultrasound can differentiate psoriatic arthritis and rheumatoid arthritis.

Tinazzi I, McGonagle D, Zabotti A, Chessa D, Marchetta A, Macchioni P.

Clin Exp Rheumatol. 2018 Sep-Oct;36(5):785-790. Epub 2018 Feb 28.


MRI of psoriatic nail disease pre- and post-TNF inhibitor therapy shows persistent subclinical inflammation after 6 months despite good clinical response.

Ash Z, Tan AL, Hodgson RJ, Grainger A, Marzo-Ortega H, McGonagle DG.

RMD Open. 2018 Feb 2;4(1):e000599. doi: 10.1136/rmdopen-2017-000599. eCollection 2018. No abstract available.


New advances in the understanding and treatment of axial spondyloarthritis: from chance to choice.

Dubash S, McGonagle D, Marzo-Ortega H.

Ther Adv Chronic Dis. 2018 Mar;9(3):77-87. doi: 10.1177/2040622317743486. Epub 2017 Dec 14. Review.

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