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Items: 48

1.

Drug Repurposing: The Anthelmintics Niclosamide and Nitazoxanide Are Potent TMEM16A Antagonists That Fully Bronchodilate Airways.

Miner K, Labitzke K, Liu B, Wang P, Henckels K, Gaida K, Elliott R, Chen JJ, Liu L, Leith A, Trueblood E, Hensley K, Xia XZ, Homann O, Bennett B, Fiorino M, Whoriskey J, Yu G, Escobar S, Wong M, Born TL, Budelsky A, Comeau M, Smith D, Phillips J, Johnston JA, McGivern JG, Weikl K, Powers D, Kunzelmann K, Mohn D, Hochheimer A, Sullivan JK.

Front Pharmacol. 2019 Feb 14;10:51. doi: 10.3389/fphar.2019.00051. eCollection 2019.

2.

Quantity, Not Quality: Rapid Adaptation in a Polygenic Trait Proceeded Exclusively through Expression Differentiation.

Margres MJ, Wray KP, Hassinger ATB, Ward MJ, McGivern JJ, Moriarty Lemmon E, Lemmon AR, Rokyta DR.

Mol Biol Evol. 2017 Dec 1;34(12):3099-3110. doi: 10.1093/molbev/msx231.

PMID:
28962003
3.

Nicorandil, a Nitric Oxide Donor and ATP-Sensitive Potassium Channel Opener, Protects Against Dystrophin-Deficient Cardiomyopathy.

Afzal MZ, Reiter M, Gastonguay C, McGivern JV, Guan X, Ge ZD, Mack DL, Childers MK, Ebert AD, Strande JL.

J Cardiovasc Pharmacol Ther. 2016 Nov;21(6):549-562. Epub 2016 Mar 2.

4.

Impact of a cytomegalovirus kinase inhibitor on infection and neuronal progenitor cell differentiation.

Bigley TM, McGivern JV, Ebert AD, Terhune SS.

Antiviral Res. 2016 May;129:67-73. doi: 10.1016/j.antiviral.2016.02.007. Epub 2016 Feb 11.

5.

Expression Differentiation Is Constrained to Low-Expression Proteins over Ecological Timescales.

Margres MJ, Wray KP, Seavy M, McGivern JJ, Herrera ND, Rokyta DR.

Genetics. 2016 Jan;202(1):273-83. doi: 10.1534/genetics.115.180547. Epub 2015 Nov 6.

6.

Pharmaceutical Optimization of Peptide Toxins for Ion Channel Targets: Potent, Selective, and Long-Lived Antagonists of Kv1.3.

Murray JK, Qian YX, Liu B, Elliott R, Aral J, Park C, Zhang X, Stenkilsson M, Salyers K, Rose M, Li H, Yu S, Andrews KL, Colombero A, Werner J, Gaida K, Sickmier EA, Miu P, Itano A, McGivern J, Gegg CV, Sullivan JK, Miranda LP.

J Med Chem. 2015 Sep 10;58(17):6784-802. doi: 10.1021/acs.jmedchem.5b00495. Epub 2015 Aug 31.

PMID:
26288216
7.

Phenotypic integration in the feeding system of the eastern diamondback rattlesnake (Crotalus adamanteus).

Margres MJ, Wray KP, Seavy M, McGivern JJ, Sanader D, Rokyta DR.

Mol Ecol. 2015 Jul;24(13):3405-20. doi: 10.1111/mec.13240. Epub 2015 Jun 15.

PMID:
25988233
8.

JBS special issue on therapeutic antibody discovery and development: biologics come of age.

McGivern JG, Howes R.

J Biomol Screen. 2015 Apr;20(4):433-6. doi: 10.1177/1087057115572999.

PMID:
25805607
9.

The transcriptomic and proteomic basis for the evolution of a novel venom phenotype within the Timber Rattlesnake (Crotalus horridus).

Rokyta DR, Wray KP, McGivern JJ, Margres MJ.

Toxicon. 2015 May;98:34-48. doi: 10.1016/j.toxicon.2015.02.015. Epub 2015 Feb 26.

PMID:
25727380
10.

RNA-seq and high-definition mass spectrometry reveal the complex and divergent venoms of two rear-fanged colubrid snakes.

McGivern JJ, Wray KP, Margres MJ, Couch ME, Mackessy SP, Rokyta DR.

BMC Genomics. 2014 Dec 3;15:1061. doi: 10.1186/1471-2164-15-1061.

11.

Contrasting modes and tempos of venom expression evolution in two snake species.

Margres MJ, McGivern JJ, Seavy M, Wray KP, Facente J, Rokyta DR.

Genetics. 2015 Jan;199(1):165-76. doi: 10.1534/genetics.114.172437. Epub 2014 Nov 11.

12.

Derivation of myogenic progenitors directly from human pluripotent stem cells using a sphere-based culture.

Hosoyama T, McGivern JV, Van Dyke JM, Ebert AD, Suzuki M.

Stem Cells Transl Med. 2014 May;3(5):564-74. doi: 10.5966/sctm.2013-0143. Epub 2014 Mar 21.

13.

Exploiting pluripotent stem cell technology for drug discovery, screening, safety, and toxicology assessments.

McGivern JV, Ebert AD.

Adv Drug Deliv Rev. 2014 Apr;69-70:170-8. doi: 10.1016/j.addr.2013.11.012. Epub 2013 Dec 2. Review.

PMID:
24309014
14.

Linking the transcriptome and proteome to characterize the venom of the eastern diamondback rattlesnake (Crotalus adamanteus).

Margres MJ, McGivern JJ, Wray KP, Seavy M, Calvin K, Rokyta DR.

J Proteomics. 2014 Jan 16;96:145-58. doi: 10.1016/j.jprot.2013.11.001. Epub 2013 Nov 12.

PMID:
24231107
15.

Spinal muscular atrophy astrocytes exhibit abnormal calcium regulation and reduced growth factor production.

McGivern JV, Patitucci TN, Nord JA, Barabas MA, Stucky CL, Ebert AD.

Glia. 2013 Sep;61(9):1418-1428. doi: 10.1002/glia.22522. Epub 2013 Jul 10.

16.

EZ spheres: a stable and expandable culture system for the generation of pre-rosette multipotent stem cells from human ESCs and iPSCs.

Ebert AD, Shelley BC, Hurley AM, Onorati M, Castiglioni V, Patitucci TN, Svendsen SP, Mattis VB, McGivern JV, Schwab AJ, Sareen D, Kim HW, Cattaneo E, Svendsen CN.

Stem Cell Res. 2013 May;10(3):417-427. doi: 10.1016/j.scr.2013.01.009. Epub 2013 Feb 4.

17.

Inhibition of apoptosis blocks human motor neuron cell death in a stem cell model of spinal muscular atrophy.

Sareen D, Ebert AD, Heins BM, McGivern JV, Ornelas L, Svendsen CN.

PLoS One. 2012;7(6):e39113. doi: 10.1371/journal.pone.0039113. Epub 2012 Jun 19.

18.

A profile of injuries in athletes seeking treatment during a triathlon race series.

Gosling CM, Forbes AB, McGivern J, Gabbe BJ.

Am J Sports Med. 2010 May;38(5):1007-14. doi: 10.1177/0363546509356979.

PMID:
20436054
19.

Toward defining the phosphoproteome of Xenopus laevis embryos.

McGivern JV, Swaney DL, Coon JJ, Sheets MD.

Dev Dyn. 2009 Jun;238(6):1433-43. doi: 10.1002/dvdy.21941.

20.

Spatially restricted translation of the xCR1 mRNA in Xenopus embryos.

Zhang Y, Forinash KD, McGivern J, Fritz B, Dorey K, Sheets MD.

Mol Cell Biol. 2009 Jul;29(13):3791-802. doi: 10.1128/MCB.01865-08. Epub 2009 Apr 13.

21.

Structural basis for RNA recognition by a type II poly(A)-binding protein.

Song J, McGivern JV, Nichols KW, Markley JL, Sheets MD.

Proc Natl Acad Sci U S A. 2008 Oct 7;105(40):15317-22. doi: 10.1073/pnas.0801274105. Epub 2008 Sep 29.

22.

The incidence of heat casualties in sprint triathlon: the tale of two Melbourne race events.

Gosling CM, Gabbe BJ, McGivern J, Forbes AB.

J Sci Med Sport. 2008 Jan;11(1):52-7. Epub 2007 Oct 10.

PMID:
17931972
23.

Advantages of voltage-gated ion channels as drug targets.

McGivern JG.

Expert Opin Ther Targets. 2007 Mar;11(3):265-71.

PMID:
17298286
24.

Ziconotide: a review of its pharmacology and use in the treatment of pain.

McGivern JG.

Neuropsychiatr Dis Treat. 2007 Feb;3(1):69-85.

25.

Pharmacology and drug discovery for T-type calcium channels.

McGivern JG.

CNS Neurol Disord Drug Targets. 2006 Dec;5(6):587-603. Review.

PMID:
17168744
26.

Characteristics of anterior cruciate ligament injuries in Australian football.

Cochrane JL, Lloyd DG, Buttfield A, Seward H, McGivern J.

J Sci Med Sport. 2007 Apr;10(2):96-104. Epub 2006 Jun 27.

PMID:
16807104
27.

Targeting N-type and T-type calcium channels for the treatment of pain.

McGivern JG.

Drug Discov Today. 2006 Mar;11(5-6):245-53. Review.

PMID:
16580601
28.

Voltage-gated calcium channels as targets for the treatment of chronic pain.

McGivern JG, McDonough SI.

Curr Drug Targets CNS Neurol Disord. 2004 Dec;3(6):457-78. Review.

PMID:
15578964
29.

Sequential IV/PO moxifloxacin treatment of patients with severe community-acquired pneumonia.

Lode H, Grossman C, Choudhri S, Haverstock D, McGivern J, Herman-Gnjidic Z, Church D.

Respir Med. 2003 Oct;97(10):1134-42.

30.

Randomized controlled trial of sequential intravenous (i.v.) and oral moxifloxacin compared with sequential i.v. and oral co-amoxiclav with or without clarithromycin in patients with community-acquired pneumonia requiring initial parenteral treatment.

Finch R, Schürmann D, Collins O, Kubin R, McGivern J, Bobbaers H, Izquierdo JL, Nikolaides P, Ogundare F, Raz R, Zuck P, Hoeffken G.

Antimicrob Agents Chemother. 2002 Jun;46(6):1746-54.

31.

Intrinsic and extrinsic risk factors for anterior cruciate ligament injury in Australian footballers.

Orchard J, Seward H, McGivern J, Hood S.

Am J Sports Med. 2001 Mar-Apr;29(2):196-200.

PMID:
11292045
32.

Regulated expression of the rat recombinant P2X(3) receptor in stably transfected CHO-K1 tTA cells.

Lachnit WG, Oglesby IB, Gever JR, Gever M, Huang C, Li XC, Jin H, McGivern JG, Ford AP.

J Auton Nerv Syst. 2000 Jul 3;81(1-3):75-81.

PMID:
10869704
33.

Rainfall, evaporation and the risk of non-contact anterior cruciate ligament injury in the Australian Football League.

Orchard J, Seward H, McGivern J, Hood S.

Med J Aust. 1999 Apr 5;170(7):304-6.

PMID:
10327970
34.

Functional analysis of a voltage-gated sodium channel and its splice variant from rat dorsal root ganglia.

Dietrich PS, McGivern JG, Delgado SG, Koch BD, Eglen RM, Hunter JC, Sangameswaran L.

J Neurochem. 1998 Jun;70(6):2262-72.

35.

Distribution of the tetrodotoxin-resistant sodium channel PN3 in rat sensory neurons in normal and neuropathic conditions.

Novakovic SD, Tzoumaka E, McGivern JG, Haraguchi M, Sangameswaran L, Gogas KR, Eglen RM, Hunter JC.

J Neurosci. 1998 Mar 15;18(6):2174-87. Review.

36.

[3H]-lifarizine, a high affinity probe for inactivated sodium channels.

MacKinnon AC, Wyatt KM, McGivern JG, Sheridan RD, Brown CM.

Br J Pharmacol. 1995 Jul;115(6):1103-9.

37.

Electrophysiological actions of phenytoin on N-methyl-D-aspartate receptor-mediated responses in rat hippocampus in vitro.

Laffling AJ, Scherr P, McGivern JG, Patmore L, Sheridan RD.

Br J Pharmacol. 1995 May;115(1):67-72.

39.
40.

Phorbol ester and lignocaine or pentobarbitone interactions at presynaptic axons.

McGivern J, Scholfield CN.

Neuroreport. 1992 Feb;3(2):139-42.

PMID:
1623161
41.
42.

Phorbol dibutyrate enhances local anaesthetic action.

Austin S, McGivern J, Scholfield CN.

Br J Pharmacol. 1991 Jan;102(1):146-50.

43.
44.

Improved survival in murine lupus as the result of selenium supplementation.

O'Dell JR, McGivern JP, Kay HD, Klassen LW.

Clin Exp Immunol. 1988 Aug;73(2):322-7.

45.

The effect of chelation on the absorption of cadmium from rat intestine in vivo.

McGivern J, Mason J.

J Comp Pathol. 1979 Apr;89(2):293-300. No abstract available.

PMID:
110853
46.

The effect of chelation on the fate of intravenously administered cadmium in rats.

McGivern J, Mason J.

J Comp Pathol. 1979 Jan;89(1):1-9. No abstract available.

PMID:
106075
47.

Sex-ratio distortion and directed alternate segregation of interchange complexes in a mosquito.

McGivern JJ, Rai KS.

J Hered. 1974 Mar-Apr;65(2):71-7. No abstract available.

PMID:
4837304
48.

A radiation-induced paracentric inversion in Aedes aegypti (L.). Cytogenetic and interchromosomal effects.

McGivern JJ, Rai KS.

J Hered. 1972 Sep-Oct;63(5):247-55. No abstract available.

PMID:
4644330

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